Intrinsic circannual rhythm controls protein dynamics in a hibernator to support rapid heat production

Abstract

A proteomics screen of brown adipose tissue in 13-lined ground squirrels reveals protein changes underlying the extreme recruitment and activity cycles characteristic of this organ in small eutherian hibernators. Protein changes precede changes in physiology, indicating endogenous timing rather than ambient temperature controls the annual recruitment-atrophy cycle in this obligate hibernator.

Keywords: :

• 14-3-3 proteins
• adaptation
• fatty acid binding proteins
• hibernation
• Ictidomys tridecemlineatus
• non-shivering thermogenesis
• torpor

This article refers to:

10.4161/temp.29627

Disclosure of Potential Conflicts of Interest

The Author states she has no conflict of interest