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Egyptian Journal of Basic and Applied Sciences Volume 3, 2016 - Issue 1
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Full Length Article

Synthesis and antitumor activity of some new pyrazolo[3,4-d]pyrimidine and pyrazolo[3,4-b]pyridine derivatives

E. Abdel-latifDepartment of Chemistry, Faculty of Science, Mansoura University, ET-35516Mansoura, EgyptCorrespondence[email protected]
,
S. Abdel-fattahDepartment of Chemistry, Faculty of Science, Mansoura University, ET-35516Mansoura, Egypt
,
H.E. GafferTextile Research Division, National Research Centre, 12622Dokki, Giza, Egypt
&
H.A. EtmanDepartment of Chemistry, Faculty of Science, Mansoura University, ET-35516Mansoura, Egypt
Pages 118-124 | Received 08 Oct 2015, Accepted 28 Nov 2015, Published online: 08 Mar 2019

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Manel Dhibi, Emna Khdhiri, Mohamed Ali Ayedi, Souhir Abid & Houcine Ammar. (2022) Microwave-assisted synthesis and reactivity of new 5-amino-1H-pyrazole derivatives bearing 2-furoyl moieties. Synthetic Communications 52:15, pages 1590-1601.
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Ranjana Aggarwal, Suresh Kumar & Gulshan Singh. (2019) Multi-component reaction to access a library of polyfunctionally substituted 4,7-dihydropyrazolo[3,4-b]pyridines. Synthetic Communications 49:7, pages 973-985.
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Articles from other publishers (15)

Nisheeth C. Desai, Ashvinkumar G. Khasiya, Dharmpalsinh J. Jadeja, Jahnvi D. Monapara, Aratiba M. Jethawa, Bharti P. Dave, Sree Kanth Sivan, Vijjulatha Manga, Pravin C. Mhaske & Doongar R. Chaudhary. (2023) Synthesis, Antifungal Ergosterol Inhibition, Antibiofilm Activities, and Molecular Docking on β-Tubulin and Sterol 14-Alpha Demethylase along with DFT-Based Quantum Mechanical Calculation of Pyrazole Containing Fused Pyridine–Pyrimidine Derivatives. ACS Omega 8:41, pages 37781-37797.
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Ghada G. El‐Bana, Wafaa S. Hamama, Hanafi H. Zoorob & Mona E. Ibrahim. (2023) An Efficient Approach for the Synthesis and Antitumor Evaluation of Novel Azo‐ and Anil‐Linked with 3‐Aminopyrazolo[3,4‐b]pyridine. Chemistry & Biodiversity 20:6.
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Asmaa E. Kassab. (2022) Pyrazolo[3,4‐ d ]pyrimidine scaffold: A review on synthetic approaches and EGFR and VEGFR inhibitory activities . Archiv der Pharmazie 356:1.
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G. G. Dubal, P. R. Vachchharajani, M. J. Solanki & V. H. Shah. (2023) Synthesis, Antibacterial, and Antifungal Screening of New Pyrazolo[3,4-d]pyrimidine Derivatives. Russian Journal of General Chemistry 92:12, pages 2734-2739.
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Dorababu Atukuri. (2022) Pyrazolopyridine: An efficient pharmacophore in recent drug design and development. Chemical Biology & Drug Design 100:3, pages 376-388.
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Satbir Mor, Mohini Khatri, Ravinder punia & Suchita Sindhu. (2022) Recent Progress in Anticancer Agents Incorporating Pyrazole Scaffold. Mini-Reviews in Medicinal Chemistry 22:1, pages 115-163.
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Aastha Mahapatra, Tanya Prasad & Tripti Sharma. (2021) Pyrimidine: a review on anticancer activity with key emphasis on SAR. Future Journal of Pharmaceutical Sciences 7:1.
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Adel A.-H. Abdel-Rahman, Amira K. F. Shaban, Ibrahim F. Nassar, Dina S. EL-Kady, Nasser S. M. Ismail, Samy F. Mahmoud, Hanem M. Awad & Wael A. El-Sayed. (2021) Discovery of New Pyrazolopyridine, Furopyridine, and Pyridine Derivatives as CDK2 Inhibitors: Design, Synthesis, Docking Studies, and Anti-Proliferative Activity. Molecules 26:13, pages 3923.
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Sanaa M. Emam, Saeyda A. Abouel‐Enein & Eman M. Abdel‐Satar. (2019) Structural characterization, thermal investigation and biological activity of metal complexes containing Schiff Base ligand (Z)‐3‐(1‐((4,6‐dimethyl‐1H‐pyrazolo[3,4‐b] pyridin‐3‐yl)imino)ethyl)‐4‐hydroxy‐6‐methyl‐2H‐pyran‐2‐one. Applied Organometallic Chemistry 33:5.
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Pramod V. Chavan, Uday V. Desai, Prakash P. Wadgaonkar, Savita R Tapase, Kisan M. Kodam, Amit Choudhari & Dhiman Sarkar. (2019) Click chemistry based multicomponent approach in the synthesis of spirochromenocarbazole tethered 1,2,3-triazoles as potential anticancer agents. Bioorganic Chemistry 85, pages 475-486.
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Khaled R.A. Abdellatif & Rania B. Bakr. (2018) New advances in synthesis and clinical aspects of pyrazolo[3,4-d]pyrimidine scaffolds. Bioorganic Chemistry 78, pages 341-357.
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Nagiri Ravi Kumar, Desireddy Krishna Swaroop, Nagender Punna, Kanugala Sirisha, Thipparapu Ganapathi, Chityal Ganesh Kumar & Banda Narsaiah. (2018) Synthesis of Novel Pyrido[2′, 3′:3,4]Pyrazolo[1, 5‐ a ]Quinazoline Derivatives, Their Biological Evaluation and Molecular Modelling Studies . ChemistrySelect 3:27, pages 7813-7821.
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Ibrahim F. Nassar, Ahmed F. El Farargy & Fathy M. Abdelrazek. (2018) Synthesis and Anticancer Activity of Some New Fused Pyrazoles and Their Glycoside Derivatives. Journal of Heterocyclic Chemistry 55:7, pages 1709-1719.
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H. Surya Prakash Rao, Lakshmi Narayana Adigopula & Krishna Ramadas. (2017) One-Pot Synthesis of Densely Substituted Pyrazolo[3,4- b ]-4,7-dihydropyridines . ACS Combinatorial Science 19:5, pages 279-285.
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P. Nagender, R. Naresh Kumar, G. Malla Reddy, D. Krishna Swaroop, Y. Poornachandra, C. Ganesh Kumar & B. Narsaiah. (2016) Synthesis of novel hydrazone and azole functionalized pyrazolo[3,4-b]pyridine derivatives as promising anticancer agents. Bioorganic & Medicinal Chemistry Letters 26:18, pages 4427-4432.
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