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Emerging Microbes & Infections Volume 3, 2014 - Issue 1
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Original Articles

A neonatal gnotobiotic pig model of human enterovirus 71 infection and associated immune responses

Xingdong YangDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Guohua LiDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Ke WenDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Tammy BuiDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Fangning LiuDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Jacob KocherDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Bernard S JortnerDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Marlice VonckDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Kevin PelzerDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USA
,
Jie DengLaboratory of Virology, Capital Institute of Pediatrics, Beijing 100020, China
,
Runan ZhuLaboratory of Virology, Capital Institute of Pediatrics, Beijing 100020, China
,
Yuyun LiLaboratory of Virology, Capital Institute of Pediatrics, Beijing 100020, China
,
Yuan QianLaboratory of Virology, Capital Institute of Pediatrics, Beijing 100020, China
&
Lijuan YuanDepartment of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0913, USACorrespondence[email protected]
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Pages 1-12 | Received 23 Sep 2015, Accepted 02 Nov 2015, Published online: 25 Jan 2019

Citations (9)

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Win Kyaw Phyu, Kien Chai Ong & Kum Thong Wong. (2017) Modelling person-to-person transmission in an Enterovirus A71 orally infected hamster model of hand-foot-and-mouth disease and encephalomyelitis. Emerging Microbes & Infections 6:1, pages 1-9.
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Articles from other publishers (8)

Qi Wang, Fei Wang, Yuanhao Zhou, Xiang Li, Shujie Xu, Qian Jin & Weifen Li. (2024) Bacillus amyloliquefaciens SC06 Relieving Intestinal Inflammation by Modulating Intestinal Stem Cells Proliferation and Differentiation via AhR/STAT3 Pathway in LPS-Challenged Piglets . Journal of Agricultural and Food Chemistry 72:12, pages 6096-6109.
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Yuan Teng Hooi, Kien Chai Ong, Soon Hao Tan, David Perera & Kum Thong Wong. (2020) A novel orally infected hamster model for Coxsackievirus A16 hand-foot-and-mouth disease and encephalomyelitis. Laboratory Investigation 100:9, pages 1262-1275.
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Ling-Hong Xiong, Xuewen He, Junjie Xia, Hanwu Ma, Fan Yang, Qian Zhang, Dana Huang, Long Chen, Chunli Wu, Xiaomin Zhang, Zheng Zhao, Chengsong Wan, Renli Zhang & Jinquan Cheng. (2017) Highly Sensitive Naked-Eye Assay for Enterovirus 71 Detection Based on Catalytic Nanoparticle Aggregation and Immunomagnetic Amplification. ACS Applied Materials & Interfaces 9:17, pages 14691-14699.
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Lijuan Yuan, Peter M. Jobst & Mariah Weiss. 2017. Gnotobiotics. Gnotobiotics 349 368 .
Carla Bianca Luena Victorio, Yishi Xu, Qimei Ng, Beng Hooi Chua, Sylvie Alonso, Vincent T. K. Chow & Kaw Bing Chua. (2016) A clinically authentic mouse model of enterovirus 71 (EV-A71)-induced neurogenic pulmonary oedema. Scientific Reports 6:1.
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Aaron J. Prussin, Amit Vikram, Kyle J. Bibby & Linsey C. Marr. (2016) Seasonal Dynamics of the Airborne Bacterial Community and Selected Viruses in a Children’s Daycare Center. PLOS ONE 11:3, pages e0151004.
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Lulu Shao, David D. Fischer, Sukumar Kandasamy, Linda J. Saif & Anastasia N. Vlasova. (2016) Tissue-specific mRNA expression profiles of porcine Toll-like receptors at different ages in germ-free and conventional pigs. Veterinary Immunology and Immunopathology 171, pages 7-16.
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Win Kyaw Phyu, Kien Chai Ong & Kum Thong Wong. (2016) A Consistent Orally-Infected Hamster Model for Enterovirus A71 Encephalomyelitis Demonstrates Squamous Lesions in the Paws, Skin and Oral Cavity Reminiscent of Hand-Foot-and-Mouth Disease. PLOS ONE 11:1, pages e0147463.
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