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Emerging Microbes & Infections Volume 6, 2017 - Issue 1
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Original Articles

Clinical features and viral quasispecies characteristics associated with infection by the hepatitis B virus G145R immune escape mutant

Yuan XueClinical Virology Research Laboratory, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Pôle Sino-Français de Recherches en Science du Vivant et Génomique, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, ChinaCorrespondence[email protected]
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Ming-Jie WangClinical Virology Research Laboratory, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Pôle Sino-Français de Recherches en Science du Vivant et Génomique, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, ChinaCorrespondence[email protected]
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Zhi-Tao YangClinical Virology Research Laboratory, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Pôle Sino-Français de Recherches en Science du Vivant et Génomique, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China
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De-Min YuClinical Virology Research Laboratory, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Pôle Sino-Français de Recherches en Science du Vivant et Génomique, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China
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Yue HanClinical Virology Research Laboratory, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Pôle Sino-Français de Recherches en Science du Vivant et Génomique, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China
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Dao HuangClinical Virology Research Laboratory, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Pôle Sino-Français de Recherches en Science du Vivant et Génomique, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China
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Dong-Hua ZhangClinical Virology Research Laboratory, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Pôle Sino-Français de Recherches en Science du Vivant et Génomique, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China
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Xin-Xin ZhangClinical Virology Research Laboratory, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Pôle Sino-Français de Recherches en Science du Vivant et Génomique, Ruijin HospitalShanghai Jiaotong University School of Medicine, Shanghai200025, China;Translational Medicine Research Center, Ruijin Hospital NorthShanghai Jiaotong University School of Medicine, Shanghai201800, China
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Pages 1-5 | Received 05 Sep 2016, Accepted 30 Dec 2016, Published online: 15 Jan 2019

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Yan Liu, Yi Zhou, Xiaodong Li, Ming Niu, Rongjuan Chen, Jinman Shao, Lanlan Si, Dan Luo, Yayun Lin, Le Li, Kai Zhang, Xiaohe Xiao, Zhihui Xu, Min Liu, Mengji Lu, Fabien Zoulim & Dongping Xu. (2019) Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice. Emerging Microbes & Infections 8:1, pages 354-365.
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Articles from other publishers (15)

Xin Liu, Shu-xiang Chen, Hui Liu & Jin-li Lou. (2023) Host immunity and HBV S gene mutation in HBsAg-negative HBV-infected patients. Frontiers in Immunology 14.
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Yulia V. Ostankova, Elena N. Serikova, Aleksandr V. Semenov, Elena B. Zueva, Diana E. Valutite, Aleksandr N. Schemelev, Vladimir A. Zurochka & Areg A. Totolian. (2023) Molecular and genetic characterization of the hepatitis B virus full-length genome sequences identified in HBsAg-negative blood donors in Ural Federal District. Journal of microbiology, epidemiology and immunobiology 99:6, pages 637-650.
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Qiao Zhan, Le Chang, Jian Wu, Zhiyuan Zhang, Jinghang Xu, Yanyan Yu, Zhenru Feng & Zheng Zeng. (2022) T-Cell Receptor β Chain and B-Cell Receptor Repertoires in Chronic Hepatitis B Patients with Coexisting HBsAg and Anti-HBs. Pathogens 11:7, pages 727.
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Junna Ye, Peilin Xie, Zhuochao Zhou, Yue Sun, Fan Wang, Yijun You, Jialin Teng, Chengde Yang, Xinxin Zhang & Yue Han. (2022) Protective Role of Rheumatic Diseases Against Hepatitis B Virus Infection and Human Leukocyte Antigen B27 Highlighted. Frontiers in Medicine 9.
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Xia Tang, Wenxun Huang, Juan Kang & Keyue Ding. (2021) Early dynamic changes of quasispecies in the reverse transcriptase region of hepatitis B virus in telbivudine treatment. Antiviral Research 195, pages 105178.
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S. Boumbaly, E. Serikova, Th. A. L. BaldeYu. V. Ostankova, A. N. Schemelev, D. Е. Valutite, E. В. Zueva, A. V. Semenov & A. A. Totolian. (2021) Amino acid substitutions in core and HBsAg regions of hepatitis B virus in patients with monoinfection and HBV/HIV-coinfection in the Republic of Guinea. HIV Infection and Immunosuppressive Disorders 13:3, pages 96-107.
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Mingjie Wang, Jianfeng Li, Xiaonan Zhang, Yue Han, Demin Yu, Donghua Zhang, Zhenghong Yuan, Zhitao Yang, Jinyan Huang & Xinxin Zhang. (2020) An integrated software for virus community sequencing data analysis. BMC Genomics 21:1.
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Bi-Xia Huang, Yan Liu, Zhen-Ping Fan, Lan-Lan Si, Rong-Juan Chen, Jun Wang, Dan Luo, Fu-Sheng Wang, Dong-Ping Xu & Xin-Guang Liu. (2020) Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations. World Journal of Gastroenterology 26:35, pages 5314-5327.
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Dan Luo, Yan Liu, Rongjuan Chen, Ming Niu, Lujie Liu, Xiaodong Li, Qi Li, Bixia Huang, Jun Wang, Dongping Xu & Shumei Lin. (2019) Investigation of hepatitis B virus (HBV) rtS78T/sC69* mutation in a large cohort of chronic HBV-infected patients with nucleoside/nucleotide analogue treatment. Antiviral Research 170, pages 104579.
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Sheng-Wen Huang, Su-Jhen Hung & Jen-Ren Wang. (2019) Application of deep sequencing methods for inferring viral population diversity. Journal of Virological Methods 266, pages 95-102.
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S. Wang, J. Wang, M‐J. Fan, T‐Y. Li, H. Pan, X. Wang, H‐K. Liu, Q‐F. Lin, J‐G. Zhang, L‐P. Guan, D. V. Zhernakova, S. J. O’Brien, Z‐R. Feng, L. Chang, E‐H. Dai, J‐H. Lu, H‐L. Xi, Z. Zeng, Y‐Y. Yu & B‐B. Wang. (2018) Identified OAS 3 gene variants associated with coexistence of HB sAg and anti‐ HB s in chronic HBV infection . Journal of Viral Hepatitis 25:8, pages 904-910.
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