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Emerging Microbes & Infections Volume 7, 2018 - Issue 1
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Original Articles

Upregulation of HBV transcription by sodium taurocholate cotransporting polypeptide at the postentry step is inhibited by the entry inhibitor Myrcludex B

Kaitao ZhaoState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina;University of Chinese Academy of Sciences100049BeijingChina
,
Shuhui LiuState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina;University of Chinese Academy of Sciences100049BeijingChina
,
Yingshan ChenState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina;University of Chinese Academy of Sciences100049BeijingChina
,
Yongxuan YaoState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina;University of Chinese Academy of Sciences100049BeijingChina
,
Ming ZhouShenzhen Xenotransplantation Research and Development Center, State and Local Joint Cancer Genome Clinical Application of Key Technology Laboratory, Shenzhen Second People’s HospitalFirst Affiliated Hospital of Shenzhen University518035ShenzhenChina
,
Yifei YuanState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina;University of Chinese Academy of Sciences100049BeijingChina
,
Yun WangState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina
,
Rongjuan PeiState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina
,
Jizheng ChenState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina
,
Xue HuState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina
,
Yuan ZhouState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina
,
He ZhaoState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina
,
Mengji LuInstitute of VirologyUniversity Hospital of Essen45147EssenGermany
,
Chunchen WuState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChinaCorrespondence[email protected]
&
Xinwen ChenState Key Laboratory of Virology, Wuhan Institute of VirologyChinese Academy of Sciences430071WuhanChina;University of Chinese Academy of Sciences100049BeijingChinaCorrespondence[email protected]
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Pages 1-14 | Received 04 Jul 2018, Accepted 26 Oct 2018, Published online: 21 Nov 2018

Citations (19)

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Hongli Yang, Fajuan Rui, Rui Li, Shengxia Yin, Qi Xue, Xinyu Hu, Yayun Xu, Chao Wu, Junping Shi & Jie Li. (2022) ADAR1 Inhibits HBV DNA Replication via Regulating miR-122-5p in Palmitic Acid Treated HepG2.2.15 Cells. Diabetes, Metabolic Syndrome and Obesity 15, pages 4035-4047.
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Articles from other publishers (18)

Abhishek Ranga, Aarti Gupta, Laxmi Yadav, Sachin Kumar & Priti Jain. (2023) Advancing beyond reverse transcriptase inhibitors: The new era of hepatitis B polymerase inhibitors. European Journal of Medicinal Chemistry 257, pages 115455.
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Canyu Liu, Kaitao Zhao, Yingshan Chen, Yongxuan Yao, Jielin Tang, Jingjing Wang, Chonghui Xu, Qi Yang, Yi Zheng, Yifei Yuan, Hao Sun, Yongli Zhang, Yuan Zhou, Jizheng Chen, Yun Wang, Chunchen Wu, Rongjuan Pei & Xinwen Chen. (2023) Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx. Journal of Virology 97:5.
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Yingshan Chen, Yongxuan Yao, Kaitao Zhao, Canyu Liu, Yifei Yuan, Hao Sun, Dan Huang, Yi Zheng, Yuan Zhou, Jizheng Chen, Yun Wang, Chunchen Wu, Bixiang Zhang, Yujuan Guan, Feng Li, Rongjuan Pei & Xinwen Chen. (2022) DNA Repair Factor Poly(ADP-Ribose) Polymerase 1 Is a Proviral Factor in Hepatitis B Virus Covalently Closed Circular DNA Formation. Journal of Virology 96:13.
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Shuhui Liu, Kaitao Zhao, Xi Su, Xiaoxiao Gao, Yongxuan Yao, Ranran Kong, Yun Wang, Chunchen Wu, Mengji Lu, Xinwen Chen & Rongjuan Pei. (2022) Enhanced host immune responses in presence of HCV facilitate HBV clearance in coinfection. Virologica Sinica 37:3, pages 408-417.
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Yanhua Tang, Hongyan Liang, Ge Zeng, Sheng Shen & Jian Sun. (2022) Advances in new antivirals for chronic hepatitis B. Chinese Medical Journal 135:5, pages 571-583.
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Shirin Nkongolo, Julius Hollnberger & Stephan Urban. (2022) Bulevirtide als erster spezifischer Wirkstoff gegen Hepatitis-D-Virusinfektionen – Mechanismus und klinische WirkungBulevirtide as the first specific agent against hepatitis D virus infections—mechanism and clinical effect. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 65:2, pages 254-263.
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Wattana Leowattana & Tawithep Leowattana. (2022) Chronic hepatitis B: New potential therapeutic drugs target. World Journal of Virology 11:1, pages 57-72.
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Kaitao Zhao, Zunhui Ke, Hongbing Hu, Yahui Liu, Aixin Li, Rong Hua, Fangteng Guo, Junfeng Xiao, Yu Zhang, Ling Duan, Xin-Fu Yan, Yong-Gui Gao, Bing Liu, Yuchen Xia & Yan Li. (2021) Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1. Microbiology Spectrum 9:1.
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Dongliang Cheng, Bing Han, Wei Zhang & Wei Wu. (2021) Clinical effects of NTCP‐inhibitor myrcludex B. Journal of Viral Hepatitis 28:6, pages 852-858.
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Jing Li, Yangyang Hu, Yifei Yuan, Yinan Zhao, Qiqi Han, Canyu Liu, Xue Hu, Yuan Zhou, Yun Wang, Yu Guo, Chunchen Wu, Xinwen Chen & Rongjuan Pei. (2020) Repurposing of Antazoline Hydrochloride as an Inhibitor of Hepatitis B Virus DNA Secretion. Virologica Sinica 36:3, pages 501-509.
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Georgia-Myrto Prifti, Dimitrios Moianos, Erofili Giannakopoulou, Vasiliki Pardali, John Tavis & Grigoris Zoidis. (2021) Recent Advances in Hepatitis B Treatment. Pharmaceuticals 14:5, pages 417.
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Jiaxuan Zhang, Ning Ling, Yu Lei, Mingli Peng, Peng Hu & Min Chen. (2021) Multifaceted Interaction Between Hepatitis B Virus Infection and Lipid Metabolism in Hepatocytes: A Potential Target of Antiviral Therapy for Chronic Hepatitis B. Frontiers in Microbiology 12.
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Lina Wu, Wenxiong Xu, Xuejun Li, Ying Liu, Lu Wang, Shu Zhu, Fangji Yang, Chan Xie & Liang Peng. (2021) The NTCP p.Ser267Phe Variant Is Associated With a Faster Anti-HBV Effect on First-Line Nucleos(t)ide Analog Treatment. Frontiers in Pharmacology 12.
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Qisong Zhang, Zhuoru He, Zhongqiu Liu & Lingzhi Gong. (2021) Integrated plasma and liver gas chromatography mass spectrometry and liquid chromatography mass spectrometry metabolomics to reveal physiological functions of sodium taurocholate cotransporting polypeptide (NTCP) with an Ntcp knockout mouse model. Journal of Chromatography B 1165, pages 122531.
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Sasan Sakiani, Bilal Asif, Alexander Yang & Christopher Koh. (2020) Role of Nucleic Acid Polymers and Entry Inhibitors in Functional Cure Strategies for HBV. Current Hepatology Reports 19:4, pages 370-381.
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Honggang Xiang, Yanmei Chen, Jifa Zhang, Jin Zhang, Dabo Pan, Bo Liu & Liang Ouyang. (2020) Discovery of a novel sodium taurocholate cotransporting polypeptide (NTCP) inhibitor: Design, synthesis, and anti-proliferative activities. Chinese Chemical Letters 31:6, pages 1422-1426.
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Yifei Yuan, Kaitao Zhao, Yongxuan Yao, Canyu Liu, Yingshan Chen, Jing Li, Yun Wang, Rongjuan Pei, Jizheng Chen, Xue Hu, Yuan Zhou, Chunchen Wu & Xinwen Chen. (2019) HDAC11 restricts HBV replication through epigenetic repression of cccDNA transcription. Antiviral Research 172, pages 104619.
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Alessandro Loglio, Peter Ferenci, Sara Colonia Uceda Renteria, Christine Y.L. Tham, Florian van Bömmel, Marta Borghi, Heidemarie Holzmann, Riccardo Perbellini, Elena Trombetta, Silvia Giovanelli, Letizia Greco, Laura Porretti, Daniele Prati, Ferruccio Ceriotti, Giovanna Lunghi, Antonio Bertoletti & Pietro Lampertico. (2019) Excellent safety and effectiveness of high-dose myrcludex-B monotherapy administered for 48 weeks in HDV-related compensated cirrhosis: A case report of 3 patients. Journal of Hepatology 71:4, pages 834-839.
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