546
Views
73
CrossRef citations to date
0
Altmetric
Research Article

a-glucosidase Inhibitors From Paraguayan Natural Medicine, Ñangapiry, The Leaves Of Eugenia Uniflora

, , , , , , & show all

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Songsong Zhang, Beibei Qiu, Jinhua Zhu, Weiping Hu, Fanyi Ma, M. Z. H. Khan & Xiuhua Liu. (2018) Rapidly screening of α-glucosidase inhibitors from Dioscorea opposita Thunb. peel based on rGO@Fe3O4 nanocomposites microreactor. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 1335-1342.
Read now
Dauda O. Araromi, Abass O. Alade, Muibat O. Bello, Taofiq Bakare, Bolanle A. Akinwande, Ahmed T. Jameel & Samuel A. Adegbola. (2017) Optimization of oil extraction from Pitanga (Eugenia uniflora L.) leaves using simplex centroid design. Separation Science and Technology 52:8, pages 1341-1349.
Read now
ArthurO. Tucker, SandraK. Jacobsen, MichaelJ. Maciarello & LeslieR. Landrum. (2011) Essential Oils from the Leaves of Eugenia pitanga (O. Berg) Kiaersk. (Myrtaceae) of Paraguay Cultivated in Arizona. Journal of Essential Oil Research 23:4, pages 43-45.
Read now
Gopan Raj, Varughese George & MathurG. Sethuraman. (2011) Chemical Analysis of Essential Oil from the Leaves of Eugenia argentea Bedd. Journal of Essential Oil Research 23:3, pages 55-57.
Read now

Articles from other publishers (69)

Ayomide H. Labulo, Oyinade A. David, Augustine D. Terna, Timileyin P. Omotosho, Nicholas S. Tanko, Ibrahim Hassan, Bosede R. Oluwole & Adeyinka Odebode. (2024) Modulation of physiological and biochemical activities of Eugenia uniflora by green-synthesized silver nanoparticle and melatonin under drought stress. Plant Biotechnology Reports 18:2, pages 289-299.
Crossref
Ayodeji Oluwabunmi Oriola, Gugulethu Mathews Miya, Moganavelli Singh & Adebola Omowunmi Oyedeji. (2023) Flavonol Glycosides from Eugenia uniflora Leaves and Their In Vitro Cytotoxicity, Antioxidant and Anti-Inflammatory Activities. Scientia Pharmaceutica 91:3, pages 42.
Crossref
Mu Chen, Run-Qiang Chen, Yuan Guo, Jian-Xin Chen, Qian Jin, Mei-Hong Chen, Bo-Yong Chen, Zheng-Chao Tu, Wen-Cai Ye & Lei Wang. (2023) Eugenilones A−N: sesquiterpenoids from the fruits of Eugenia uniflora. Phytochemistry 211, pages 113699.
Crossref
Mikhail Elyashberg, Sriram Tyagarajan, Mihir Mandal & Alexei V. Buevich. (2023) Enhancing Efficiency of Natural Product Structure Revision: Leveraging CASE and DFT over Total Synthesis. Molecules 28:9, pages 3796.
Crossref
Yi-Xian Li, Jun-Zhe Wang, Yuna Shimadate, Maki Kise, Atsushi Kato, Yue-Mei Jia, George W.J. Fleet & Chu-Yi Yu. (2022) C-6 fluorinated casuarines as highly potent and selective amyloglucosidase inhibitors: Synthesis and structure-activity relationship study. European Journal of Medicinal Chemistry 244, pages 114852.
Crossref
Stephen G. Pyne. (2022) My 37 years of working with nitrogen heterocycles and alkaloids. Australian Journal of Chemistry 75:11, pages 923-944.
Crossref
Magda Rhayanny Assunção Ferreira, Alessandra Daniele-Silva, Lucas Ferreira de Almeida, Ewelyn Cintya Felipe dos Santos, Janaina Carla Barbosa Machado, Alisson Macário de Oliveira, Matheus de Freitas Fernandes Pedrosa, Patrícia Maria Guedes Paiva, Thiago Henrique Napoleão & Luiz Alberto Lira Soares. (2022) Safety evaluation of aqueous extract from Eugenia uniflora leaves: Acute and subacute toxicity and genotoxicity in vivo assays. Journal of Ethnopharmacology 298, pages 115668.
Crossref
Xiaoyan Zhu, Xiaohong Chen, Longshan Qiu, Jianhua Zhu & Jiancai Wang. (2022) Norcantharidin induces ferroptosis via the suppression of NRF2/HO‑1 signaling in ovarian cancer cells. Oncology Letters 24:4.
Crossref
Yi-Xian Li, Jun-Zhe Wang, Yuna Shimadate, Maki Kise, Atsushi Kato, Yue-Mei Jia, George W. J. FleetChu-Yi Yu. (2022) Diastereoselective Synthesis, Glycosidase Inhibition, and Docking Study of C-7-Fluorinated Casuarine and Australine Derivatives. The Journal of Organic Chemistry 87:11, pages 7291-7307.
Crossref
In-Soo Myeong & Won-Hun Ham. (2022) Stereoselective Total Synthesis of (+)-Casuarine via a Functionalized Pyrrolidine. Synthesis 54:10, pages 2473-2479.
Crossref
Manal Fawzy ELKHADRAGY, Nawal Salem Mohammed Al AQEEL, Hany Mohamed YEHIA, Rewaida ABDEL-GABER & Sherifa Shaker HAMED. (2022) Histological and molecular characterization of the protective effect of Eugenia caryophyllata against renal toxicity induced by vitamin D in male wistar rats. Food Science and Technology 42.
Crossref
Yi-Xian Li, Jun-Zhe Wang, Atsushi Kato, Yuna Shimadate, Maki Kise, Yue-Mei Jia, George W. J. Fleet & Chu-Yi Yu. (2021) Stereocomplementary synthesis of casuarine and its 6- epi -, 7- epi -, and 6,7-di epi -stereoisomers . Organic & Biomolecular Chemistry 19:43, pages 9410-9420.
Crossref
Nayara Macêdo Peixoto Araujo, Henrique Silvano Arruda, David de Paulo Farias, Gustavo Molina, Gustavo Araujo Pereira & Glaucia Maria Pastore. (2021) Plants from the genus Eugenia as promising therapeutic agents for the management of diabetes mellitus: A review. Food Research International 142, pages 110182.
Crossref
Leonardo M. Anconatani, Ignacio J. Agudelo, Rafael A. Ricco & Marcelo L. Wagner. 2021. Medicinal and Aromatic Plants of South America Vol. 2. Medicinal and Aromatic Plants of South America Vol. 2 191 203 .
Carla Giovana Luciano, Flávia C. Vargas, Larissa Tessaro, Marco A. Trindade, Lucas Arantes-Pereira, Andrezza M. Fernandes & Paulo José do A. Sobral. 2021. Sustainable Innovation in Food Product Design. Sustainable Innovation in Food Product Design 3 23 .
Camilla Matassini, Camilla Parmeggiani & Francesca Cardona. (2020) New Frontiers on Human Safe Insecticides and Fungicides: An Opinion on Trehalase Inhibitors. Molecules 25:13, pages 3013.
Crossref
Washim Khan, Sultan Zahiruddin & Sayeed Ahmad. 2020. Bioactive Natural Products. Bioactive Natural Products 117 155 .
Luiz Everson da Silva, Camila Confortin, Michele Debiasi Alberton, Diogo Alexandre Siebert & Camila Jeriane Paganelli. 2020. Plant-derived Bioactives. Plant-derived Bioactives 383 393 .
Salehi, Ata, V. Anil Kumar, Sharopov, Ramírez-Alarcón, Ruiz-Ortega, Abdulmajid Ayatollahi, Tsouh Fokou, Kobarfard, Amiruddin Zakaria, Iriti, Taheri, Martorell, Sureda, Setzer, Durazzo, Lucarini, Santini, Capasso, Ostrander, Atta-ur-Rahman, Choudhary, Cho & Sharifi-Rad. (2019) Antidiabetic Potential of Medicinal Plants and Their Active Components. Biomolecules 9:10, pages 551.
Crossref
Anthony W. Carroll & Stephen G. Pyne. (2019) The History of the Glycosidase Inhibiting Hyacinthacine C-type Alkaloids: From Discovery to Synthesis.. Current Organic Synthesis 16:4, pages 498-522.
Crossref
Gabriela Silva Moura, Ivan Júnior de Oliveira, Lisandro Tomas da Silva Bonome & Gilmar Franzener. (2018) Eugenia uniflora L.: potential uses as a bioactive plant. Arquivos do Instituto Biológico 85:0.
Crossref
Xiaoli Wang, Fanxing Xu, Henghui Zhang, Liang Peng, Yuhong Zhen, Lili Wang, Yongping Xu, Dongye He & Xiaoyu Li. (2018) Orthogonal test design for optimization of the extraction of essential oil from Asarum heterotropoides var. Mandshuricum and evaluation of its antibacterial activity against periodontal pathogens. 3 Biotech 8:11.
Crossref
Andréia Limana Tambara, Liliana de Los Santos Moraes, Ana Helena Dal Forno, Jean Ramos Boldori, Ana Thalita Gonçalves Soares, Cristiane de Freitas Rodrigues, Lilian Regina Barros Mariutti, Adriana Zerlotti Mercadante, Daiana Silva de Ávila & Cristiane Casagrande Denardin. (2018) Purple pitanga fruit (Eugenia uniflora L.) protects against oxidative stress and increase the lifespan in Caenorhabditis elegans via the DAF-16/FOXO pathway. Food and Chemical Toxicology 120, pages 639-650.
Crossref
Bin Cheng, Yuki Hirokami, Yi-Xian Li, Atsushi Kato, Yue-Mei Jia & Chu-Yi Yu. (2017) Synthesis and glycosidase inhibition of C-7 modified casuarine derivatives. Chinese Chemical Letters 28:8, pages 1701-1704.
Crossref
Paulo R.R. Mesquita, Estéfane C. Nunes, Fábio N. dos Santos, Lucimário P. Bastos, Maria A.P.C. Costa, Frederico de M. Rodrigues & Jailson B. de Andrade. (2017) Discrimination of Eugenia uniflora L. biotypes based on volatile compounds in leaves using HS-SPME/GC–MS and chemometric analysis. Microchemical Journal 130, pages 79-87.
Crossref
Ján Elečko, Jozef Gonda, Miroslava Martinková & Mária Vilková. (2016) Contribution to the synthesis of polyhydroxylated indolizidines starting from sugar isothiocyanates. Tetrahedron: Asymmetry 27:7-8, pages 346-351.
Crossref
Appian Subramoniam. 2016. Plants with Anti-Diabetes Mellitus Properties. Plants with Anti-Diabetes Mellitus Properties 441 567 .
Joseph P. Michael. 2016. 1 498 .
Camilla Parmeggiani, Serena Catarzi, Camilla Matassini, Giampiero D'Adamio, Amelia Morrone, Andrea Goti, Paolo Paoli & Francesca Cardona. (2015) Human Acid β‐Glucosidase Inhibition by Carbohydrate Derived Iminosugars: Towards New Pharmacological Chaperones for Gaucher Disease. ChemBioChem 16:14, pages 2054-2064.
Crossref
Atsushi Kato, Yuki Hirokami, Kyoko Kinami, Yutaro Tsuji, Shota Miyawaki, Isao Adachi, Jackie Hollinshead, Robert J. Nash, J.L. Kiappes, Nicole Zitzmann, Jin K. Cha, Russell J. Molyneux, George W.J. Fleet & Naoki Asano. (2015) Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors. Phytochemistry 111, pages 124-131.
Crossref
Giampiero D'Adamio, Antonella Sgambato, Matilde Forcella, Silvia Caccia, Camilla Parmeggiani, Morena Casartelli, Paolo Parenti, Davide Bini, Laura Cipolla, Paola Fusi & Francesca Cardona. (2015) New synthesis and biological evaluation of uniflorine A derivatives: towards specific insect trehalase inhibitors. Organic & Biomolecular Chemistry 13:3, pages 886-892.
Crossref
Fernanda P.S. Ferreira, Sandra R. Morais, Maria T.F. Bara, Edemilson C. Concei??o, Jos? R. Paula, Thays C. Carvalho, Boniek G. Vaz, Helber B. Costa, Wanderson Rom?o & Maria H. Rezende. (2014) Eugenia calycina Cambess extracts and their fractions: Their antimicrobial activity and the identification of major polar compounds using electrospray ionization FT-ICR mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 99, pages 89-96.
Crossref
Alda Lisa Concia, Livia Gómez, Teodor Parella, Jesús Joglar & Pere Clapés. (2014) Casuarine Stereoisomers from Achiral Substrates: Chemoenzymatic Synthesis and Inhibitory Properties. The Journal of Organic Chemistry 79:11, pages 5386-5389.
Crossref
Hun-Su SeoKyoung Hee KimDae-Yong KimBong-Kyun ParkNam-Shik ShinJae-Hoon KimHeejeong Youn. (2013) GC/MS analysis of high-performance liquid chromatography fractions from Sophora flavescens and Torilis japonica extracts and their in vitro anti-neosporal effects on Neospora caninum . Journal of Veterinary Science 14:3, pages 241.
Crossref
Stephen G. Pyne, Andrew S. Davis, Thunwadee Ritthiwigrom, Christopher W. G. Au, Kongdech Savaspun & Matthew Wotherspoon. (2012) The boronic acid Mannich reaction in alkaloid synthesis. Pure and Applied Chemistry 85:6, pages 1215-1225.
Crossref
Frank Guzman, Mauricio P. Almer?o, Ana P. K?rbes, Guilherme Loss-Morais & Rogerio Margis. (2012) Identification of MicroRNAs from Eugenia uniflora by High-Throughput Sequencing and Bioinformatics Analysis. PLoS ONE 7:11, pages e49811.
Crossref
Sharad Chandrakant Deshmukh, Arundhati Roy & Pinaki Talukdar. (2012) Diastereoselective construction of syn-α-oxyamines via three-component α-oxyaldehyde–dibenzylamine–alkyne coupling reaction: application in the synthesis of (+)-β-conhydrine and its analogues. Organic & Biomolecular Chemistry 10:37, pages 7536.
Crossref
Thunwadee Ritthiwigrom & Stephen G. Pyne. 2012. Bioactive Natural Products. Bioactive Natural Products 1 26 .
Timothy R. Ramadhar & Robert A. Batey. 2011. Boronic Acids. Boronic Acids 427 477 .
Juliano Lemos Bicas, Gustavo Molina, Ana Paula Dionísio, Francisco Fábio Cavalcante Barros, Roger Wagner, Mário Roberto MarósticaJr.Jr. & Gláucia Maria Pastore. (2011) Volatile constituents of exotic fruits from Brazil. Food Research International 44:7, pages 1843-1855.
Crossref
Xue-Kui Liu, Shi Qiu, Yong-Gang Xiang, Yuan-Ping Ruan, Xiao Zheng & Pei-Qiang Huang. (2011) SmI 2 -Mediated Radical Cross-Couplings of α-Hydroxylated Aza-hemiacetals and N , S -Acetals with α,β-Unsaturated Compounds: Asymmetric Synthesis of (+)-Hyacinthacine A 2 , (−)-Uniflorine A, and (+)-7- epi -Casuarine . The Journal of Organic Chemistry 76:12, pages 4952-4963.
Crossref
Felipe S. Malaman, Luiz Alberto B. Moraes, Caroline West, Nilson J. Ferreira & Alessandra L. Oliveira. (2011) Supercritical fluid extracts from the Brazilian cherry (Eugenia uniflora L.): Relationship between the extracted compounds and the characteristic flavour intensity of the fruit. Food Chemistry 124:1, pages 85-92.
Crossref
Bochra Kouidhi, Tarek Zmantar & Amina Bakhrouf. (2010) Anticariogenic and cytotoxic activity of clove essential oil (Eugenia caryophyllata) against a large number of oral pathogens. Annals of Microbiology 60:4, pages 599-604.
Crossref
Thunwadee Ritthiwigrom, Robert J. Nash & Stephen G. Pyne. (2010) Synthesis of polyhydroxylated pyrrolizidine and indolizidine compounds and their glycosidase inhibitory activities. Tetrahedron 66:48, pages 9340-9347.
Crossref
CAMILA A. PEIXOTO, ALESSANDRA L. OLIVEIRA & FERNANDO A. CABRAL. (2009) COMPOSITION OF SUPERCRITICAL CARBON DIOXIDE EXTRACTS OF PITANGA ( EUGENIA UNIFLORA L.) LEAVES . Journal of Food Process Engineering 33:5, pages 848-860.
Crossref
Thunwadee Ritthiwigrom, Anthony C. Willis & Stephen G. Pyne. (2009) Total Synthesis of Uniflorine A, Casuarine, Australine, 3- epi -Australine, and 3,7-Di- epi -australine from a Common Precursor . The Journal of Organic Chemistry 75:3, pages 815-824.
Crossref
Alan D. Elbein & Russell J. Molyneux. 2010. Comprehensive Natural Products II. Comprehensive Natural Products II 225 260 .
Tibor CserhátiTibor Cserháti. 2010. Chromatography of Aroma Compounds and Fragrances. Chromatography of Aroma Compounds and Fragrances 13 268 .
Camilla Parmeggiani, Daniele Martella, Francesca Cardona & Andrea Goti. (2009) Total Synthesis of (−)-Uniflorine A. Journal of Natural Products 72:11, pages 2058-2060.
Crossref
Alessandra L. Oliveira, Eliana S. Kamimura & Jos? A. Rabi. (2009) Response surface analysis of extract yield and flavour intensity of Brazilian cherry (Eugenia uniflora L.) obtained by supercritical carbon dioxide extraction. Innovative Food Science & Emerging Technologies 10:2, pages 189-194.
Crossref
Sebastian Stecko, Jolanta Solecka & Marek Chmielewski. (2009) Synthesis of casuarine-related derivatives via 1,3-dipolar cycloaddition between a cyclic nitrone and an unsaturated γ-lactone. Carbohydrate Research 344:2, pages 167-176.
Crossref
Antonio P. Souza, Maria R. Marques, Talal S. Mahmoud, Bruno A. Caputo, Gabriel M. Canhete, Carla B. Leite & Dênis P. de Lima. (2008) Bioprospecting insecticidal compounds from plants native to Mato Grosso do Sul, Brazil. Acta Botanica Brasilica 22:4, pages 1136-1140.
Crossref
Ige Joseph Kade, Emmanuel Oluwafemi Ibukun, Cristina Wayne Nogueira & Joao Batista Teixeira da Rocha. (2008) Sun-drying diminishes the antioxidative potentials of leaves of Eugenia uniflora against formation of thiobarbituric acid reactive substances induced in homogenates of rat brain and liver. Experimental and Toxicologic Pathology 60:4-5, pages 365-371.
Crossref
Thunwadee Ritthiwigrom & Stephen G. Pyne. (2008) Synthesis of (+)-Uniflorine A: A Structural Reassignment and a Configurational Assignment. Organic Letters 10:13, pages 2769-2771.
Crossref
Andrew S. Davis, Thunwadee Ritthiwigrom & Stephen G. Pyne. (2008) Synthetic and spectroscopic studies on the structures of uniflorines A and B: structural revision to 1,2,6,7-tetrahydroxy-3-hydroxymethylpyrrolizidine alkaloids. Tetrahedron 64:21, pages 4868-4879.
Crossref
Stephen G. Pyne, Christopher W. G. Au, Andrew S. Davis, Ian R. Morgan, Thunwadee Ritthiwigrom & Arife Yazici. (2008) Exploiting the borono-Mannich reaction in bioactive alkaloid synthesis. Pure and Applied Chemistry 80:4, pages 751-762.
Crossref
Joseph P. Michael. (2008) Indolizidine and quinolizidine alkaloids. Nat. Prod. Rep. 25:1, pages 139-165.
Crossref
Anders E. Håkansson, Jeroen van Ameijde, Graeme Horne, Robert J. Nash, Mark R. Wormald, Atsushi Kato, Gurdyal S. Besra, Sudagar Gurcha & George W.J. Fleet. (2008) Synthesis of the naringinase inhibitors l-swainsonine and related 6-C-methyl-l-swainsonine analogues: (6R)-C-methyl-l-swainsonine is a more potent inhibitor of l-rhamnosidase by an order of magnitude than l-swainsonine. Tetrahedron Letters 49:1, pages 179-184.
Crossref
K. S. Ajish Kumar, Vinod D. Chaudhari, Vedavati. G. Puranik & Dilip D. Dhavale. (2007) Synthesis and Glycosidase Inhibitory Studies of Pentahydroxyindolizidines: D ‐Glucose‐Derived Aziridine‐2‐carboxylate Approach . European Journal of Organic Chemistry 2007:29, pages 4895-4901.
Crossref
Kamel Chaieb, Tarek Zmantar, Riadh Ksouri, Hafedh Hajlaoui, Kacem Mahdouani, Chedly Abdelly & Amina Bakhrouf. (2007) Antioxidant properties of the essential oil of Eugenia caryophyllata and its antifungal activity against a large number of clinical Candida species . Mycoses 50:5, pages 403-406.
Crossref
Ma Isabel Torres-S?nchez, Pastora Borrachero, Francisca Cabrera-Escribano, Manuel G?mez-Guill?n, Manuel Angulo-?lvarez, Eleuterio ?lvarez, Sylvain Favre & Pierre Vogel. (2007) Efficient synthesis of 2,6,7,8-tetrahydroxyindolizidines (castanospermine analogues) via the dipolar cycloadditions of N-benzyl-C-(tetrofuranos-4-yl)nitrones to methyl acrylate. Tetrahedron: Asymmetry 18:15, pages 1809-1827.
Crossref
Narayan S. Karanjule, Shankar D. Markad & Dilip D. Dhavale. (2006) Synthesis of Pentahydroxy Indolizidine Alkaloids Using Ring Closing Metathesis:  Attempts To Find the Correct Structure of Uniflorine A. The Journal of Organic Chemistry 71:16, pages 6273-6276.
Crossref
Alessandra L. Oliveira, Roberta B. Lopes, Fernando A. Cabral & Marcos N. Eberlin. (2006) Volatile compounds from pitanga fruit (Eugenia uniflora L.). Food Chemistry 99:1, pages 1-5.
Crossref
Zhiming Zhao, Ling Song & Patrick S. Mariano. (2005) A concise sequential photochemical-metathesis approach for the synthesis of (+)-castanospermine and possible uniflorine-A stereoisomers. Tetrahedron 61:37, pages 8888-8894.
Crossref
Joseph P. Michael. (2005) Indolizidine and quinolizidine alkaloids. Natural Product Reports 22:5, pages 603.
Crossref
Andrew S. Davis, Stephen G. Pyne, Brian W. Skelton & Allan H. White. (2004) Synthesis of Putative Uniflorine A. The Journal of Organic Chemistry 69:9, pages 3139-3143.
Crossref
G. Coelho de Souza, A.P.S. Haas, G.L. von Poser, E.E.S. Schapoval & E. Elisabetsky. (2004) Ethnopharmacological studies of antimicrobial remedies in the south of Brazil. Journal of Ethnopharmacology 90:1, pages 135-143.
Crossref
Mariangela T. Auricchio & Elfried. M. Bacchi. (2003) Folhas de Eugenia uniflora L. (pitanga): propriedades farmacobotânicas, químicas e farmacológicas. Revista do Instituto Adolfo Lutz 62:1, pages 55-61.
Crossref
K. Morioka, H. Nojima, F. Kurosaki, M. Arisawa, Y. Kuraishi & Y. Momose. (2000) Hypotensive action of Ñangapiry, a Paraguayan Natural Medicine, in rodents. Phytomedicine 7:2, pages 99-103.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.