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Current Eye Research Volume 21, 2000 - Issue 6
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Research Article

Comparison of various calpain inhibitors in reduction of light scattering, protein precipitation and nuclear cataract in vitro

Priya Mathur Dept. of Pharmacology, Dept. of Biotechnology and Dr. R.P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi-29, India and Dept. of Experimental Ophthalmology, University of Bonn, D-53105 Bonn, Germany
,
Suresh K. Gupta Dept. of Pharmacology, Dept. of Biotechnology and Dr. R.P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi-29, India and Dept. of Experimental Ophthalmology, University of Bonn, D-53105 Bonn, Germany
,
Alfred R. Wegener Dept. of Pharmacology, Dept. of Biotechnology and Dr. R.P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi-29, India and Dept. of Experimental Ophthalmology, University of Bonn, D-53105 Bonn, Germany
,
Winrich Breipohl Dept. of Pharmacology, Dept. of Biotechnology and Dr. R.P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi-29, India and Dept. of Experimental Ophthalmology, University of Bonn, D-53105 Bonn, Germany
,
Michael H. Ahrend Dept. of Pharmacology, Dept. of Biotechnology and Dr. R.P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi-29, India and Dept. of Experimental Ophthalmology, University of Bonn, D-53105 Bonn, Germany
,
Yagya D. Sharma Dept. of Pharmacology, Dept. of Biotechnology and Dr. R.P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi-29, India and Dept. of Experimental Ophthalmology, University of Bonn, D-53105 Bonn, Germany
,
Yogendra K. Gupta Dept. of Pharmacology, Dept. of Biotechnology and Dr. R.P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi-29, India and Dept. of Experimental Ophthalmology, University of Bonn, D-53105 Bonn, Germany
&
Rasik B. Vajpayee Dept. of Pharmacology, Dept. of Biotechnology and Dr. R.P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi-29, India and Dept. of Experimental Ophthalmology, University of Bonn, D-53105 Bonn, Germany
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Pages 926-933 | Published online: 02 Jul 2009

Citations (15)

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Hitoshi Shichi. (2004) Cataract formation and prevention. Expert Opinion on Investigational Drugs 13:6, pages 691-701.
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Articles from other publishers (14)

A. Biswas, S. Karmakar, A. Chowdhury & K.P. Das. (2016) Interaction of α-crystallin with some small molecules and its effect on its structure and function. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:1, pages 211-221.
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Arumugam Ramachandran Muralidharan, Chandrabose Selvaraj, Sanjeev Kumar Singh, C. A. Nelson Jesudasan, Pitchairaj Geraldine & Philip A. Thomas. (2013) Virtual screening based on pharmacophoric features of known calpain inhibitors to identify potent inhibitors of calpain. Medicinal Chemistry Research 23:5, pages 2445-2455.
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Raghu Hariharapura, Puttur Santhoshkumar & K. Krishna Sharma. (2013) Profiling of lens protease involved in generation of αA-66-80 crystallin peptide using an internally quenched protease substrate. Experimental Eye Research 109, pages 51-59.
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Jeong A Lim, Sung Ho Hwang, Min Jeong Kim, Sang Soo Kim & Hye Sun Kim. (2012) N‐terminal cleavage fragment of focal adhesion kinase is required to activate the survival signalling pathway in cultured myoblasts under oxidative stress. The FEBS Journal 279:19, pages 3573-3583.
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Guo-Li Xie, Hong Yan & Zi-Fan Lu. (2010) Inhibition of glucocorticoid-induced changes of Na+, K+-ATPase in rat lens by a glucocorticoid receptor antagonist RU486. Experimental Eye Research 91:4, pages 544-549.
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Puttur Santhoshkumar, Padmanabha Udupa, Raju Murugesan & K. Krishna Sharma. (2008) Significance of Interactions of Low Molecular Weight Crystallin Fragments in Lens Aging and Cataract Formation. Journal of Biological Chemistry 283:13, pages 8477-8485.
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Dominic Cuerrier, Tudor Moldoveanu, Robert L. Campbell, Jacqueline Kelly, Bilge Yoruk, Steven H.L. Verhelst, Doron Greenbaum, Matthew Bogyo & Peter L. Davies. (2007) Development of Calpain-specific Inactivators by Screening of Positional Scanning Epoxide Libraries. Journal of Biological Chemistry 282:13, pages 9600-9611.
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Moazez J. Marian, Partha Mukhopadhyay, Douglas Borchman, Daxin Tang & Christopher A. Paterson. (2007) Regulation of sarco/endoplasmic and plasma membrane calcium ATPase gene expression by calcium in cultured human lens epithelial cells. Cell Calcium 41:1, pages 87-95.
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Carmen Drahl, Benjamin F. Cravatt & Erik J. Sorensen. (2005) Protein‐Reactive Natural Products. Angewandte Chemie International Edition 44:36, pages 5788-5809.
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Carmen Drahl, Benjamin F. Cravatt & Erik J. Sorensen. (2005) Proteinreaktive Naturstoffe. Angewandte Chemie 117:36, pages 5936-5958.
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Suman Biswas, Frederick Harris, Sarah Dennison, Jaipaul Singh & David A. Phoenix. (2004) Calpains: targets of cataract prevention?. Trends in Molecular Medicine 10:2, pages 78-84.
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Richard J. Payne, Karina M. Brown, James M. Coxon, James D. Morton, Hannah Yun-Young Lee & Andrew D. Abell. (2004) Peptidic Aldehydes Based on α- and β-Amino Acids: Synthesis, Inhibition of m-Calpain, and Anti-Cataract Properties. Australian Journal of Chemistry 57:9, pages 877.
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Monica M. Lurtz & Charles F. Louis. (2003) Calmodulin and protein kinase C regulate gap junctional coupling in lens epithelial cells. American Journal of Physiology-Cell Physiology 285:6, pages C1475-C1482.
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Priya Mathur, Igor V. Peshenko & Hitoshi Shichi. (2003) Cellular Events Preceding Acetaminophen Cataractogenesis Studied by Confocal Fluorescence Microscopy. Journal of Ocular Pharmacology and Therapeutics 19:5, pages 483-492.
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