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International Journal of Pharmacognosy Volume 35, 1997 - Issue 2
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Research Article

Oleanolic Acid, a Bioactive Component of the Leaves of Ocimum Gratissimum (Lamiaceae)

C.J. Njoku Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria; Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907-1333, U.S.A.
,
Lu Zeng Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria
,
I.U. Asuzu Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria
,
N.H. Oberlies Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria
&
J.L. McLaughlin Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria
Pages 134-137 | Published online: 29 Sep 2008

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N.O. Agbenin. (2014) Effect of aqueous extract of some plants on soil micro-fauna and micro-flora in vitro. Archives of Phytopathology and Plant Protection 47:2, pages 205-211.
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A. Senthilkumar, S.N. Tikar, N. Gopalan, P. Sundaramoorthy & V. Venkatesalu. (2012) Larvicidal potential of different solvent extracts and oleanolic acid derivative from Coccinia indica against vector mosquitoes. Toxicological & Environmental Chemistry 94:7, pages 1342-1349.
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Basiru Olaitan Ajiboye, Toluwase Hezekiah Fatoki, Precious Ayorinde Akinnusi, Olawale Rasaq Ajuwon, Babatunji Emmanuel Oyinloye, Temitope Olawale Jeje, Olutunmise Victoria Owolabi, Oluwatosin O. Ogedengbe & Claudia Genovese. Molecular docking, MMGBSA, and ADMET studies of phytoconstituents of Ocimum gratissimum on multiple breast cancer targets. Natural Product Research 0:0, pages 1-9.
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Articles from other publishers (20)

Franklyn O. Ohiagu, Paul C. Chikezie, Chinwendu M. Chikezie & Christian E. Enyoh. (2021) Anticancer activity of Nigerian medicinal plants: a review. Future Journal of Pharmaceutical Sciences 7:1.
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Prerna Sharma & Kumud Upadhyaya. (2021) Pharmacognostic and Therapeutic Activities of Genus Ocimum. Anti-Infective Agents 19:1, pages 85-90.
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Eman Maher Zahran, Usama Ramadan Abdelmohsen, Hany Ezzat Khalil, Samar Yehia Desoukey, Mostafa Ahmed Fouad & Mohamed Salah Kamel. (2020) Diversity, phytochemical and medicinal potential of the genus Ocimum L. (Lamiaceae). Phytochemistry Reviews 19:4, pages 907-953.
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Kayode Ezekiel Adewole. (2020) Nigerian antimalarial plants and their anticancer potential: A review. Journal of Integrative Medicine 18:2, pages 92-113.
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Hyun Woo Kil, Taewoong Rho & Kee Dong Yoon. (2019) Phytochemical Study of Aerial Parts of Leea asiatica. Molecules 24:9, pages 1733.
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Renan Gianoti Torres, Livia Casanova, Julia Carvalho, Mariah Celestino Marcondes, Sonia Soares Costa, Mauro Sola-Penna & Patricia Zancan. (2018) Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway. Journal of Bioenergetics and Biomembranes 50:2, pages 93-105.
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Varinder Singh, Aditi Kahol, Inder Pal Singh, Isha Saraf & Richa Shri. (2016) Evaluation of anti-amnesic effect of extracts of selected Ocimum species using in-vitro and in-vivo models. Journal of Ethnopharmacology 193, pages 490-499.
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Wencheng Zhang, Qing Zhang, Xingyuan Zhang, Zeyu Wu, Bing Li, Xiuli Dong & Bingsong Wang. (2016) Preparation and evaluation of molecularly imprinted composite membranes for inducing crystallization of oleanolic acid in supercritical CO 2 . Analytical Methods 8:28, pages 5651-5657.
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de Lima Silva Lenise, Giesel Heldwein Clarissa, Gustavo Brenner Reetz Luiz, Zanella Renato, Maria Soares Pereira Ana & Maria Heinzmann Berta. (2015) Influence of extraction method on antibacterial activity of ethanolic extracts of Ocimum gratissimum L.. Journal of Medicinal Plants Research 9:7, pages 199-206.
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AugustineOseloka Ibegbu, SuleimanMuhammed Eze, PrincessPaschal Livinus, SadeeqAbubaka Adamu, OliverWilson Hamman, UduakEmmanuel Umana & SundayAbraham Musa. (2015) Effect of ethanolic extract of Ocimum gratissimum on sodium nitrite-induced cerebellar cortex toxicity in adult Wistar rats. Journal of Experimental and Clinical Anatomy 14:2, pages 120.
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Udoamaka F. Ezuruike & Jose M. Prieto. (2014) The use of plants in the traditional management of diabetes in Nigeria: Pharmacological and toxicological considerations. Journal of Ethnopharmacology 155:2, pages 857-924.
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Regina Geris, Paulo Roberto Ribeiro, Maurício Da Silva Brandão, Heloísa Helena Garcia Da Silva & Ionizete Garcia Da Silva. 2012. Studies in Natural Products Chemistry Volume 37. Studies in Natural Products Chemistry Volume 37 277 376 .
Ligang Zhou, Jingguo Wang, Kui Wang, Jianmei Xu, Jianglin Zhao, Tijiang Shan & Chao Luo. 2012. 67 114 .
Lien-Chai ChiangWin ChiangMei-Yin ChangLean-Teik NgChun-Ching Lin. (2012) Antileukemic Activity of Selected Natural Products in Taiwan. The American Journal of Chinese Medicine 31:01, pages 37-46.
Crossref
David J. Chitwood. (2002) P HYTOCHEMICAL B ASED S TRATEGIES FOR N EMATODE C ONTROL . Annual Review of Phytopathology 40:1, pages 221-249.
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Emilio L. Ghisalberti. 2002. Bioactive Natural Products. Bioactive Natural Products 425 506 .
Lara O Orafidiya, A.O Oyedele, A.O Shittu & A.A Elujoba. (2001) The formulation of an effective topical antibacterial product containing Ocimum gratissimum leaf essential oil. International Journal of Pharmaceutics 224:1-2, pages 177-183.
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B. B. Fakae, A. M. Campbell, J. Barrett, I. M. Scott, P. H. Teesdale-Spittle, E. Liebau & P. M. Brophy. (2000) Inhibition of glutathione S-transferases (GSTs) from parasitic nematodes by extracts from traditional Nigerian medicinal plants. Phytotherapy Research 14:8, pages 630-634.
Crossref
Jerry L. McLaughlin & Ching-Jer Chang. 1999. Phytochemicals in Human Health Protection, Nutrition, and Plant Defense. Phytochemicals in Human Health Protection, Nutrition, and Plant Defense 89 132 .
C.J. Njoku & I.U. Asuzu. (1998) The anthelmintic effects of the leaf extract of Ocimum gratissimum (L.). Phytomedicine 5:6, pages 485-488.
Crossref

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