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Acta Chirurgica Belgica Volume 103, 2003 - Issue 3
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Experimental Surgery

Influence of Neo-Adjuvant Chemotherapy with 5-Fluorouracil on Colonic Anastomotic Healing: Experimental Study in Rats

M. El-MaltDepartment of Abdominal Surgery, Ghent University Hospital, Ghent University, Belgium.View further author information
,
W. CeelenDepartment of Abdominal Surgery, Ghent University Hospital, Ghent University, Belgium.
,
C. Van den BroeckeDepartment of Pathology, Ghent University Hospital, Ghent University, Belgium.
,
C. CuvelierDepartment of Pathology, Ghent University Hospital, Ghent University, Belgium.
,
S. Van BelleDepartment of Medical Oncology, Ghent University Hospital, Ghent University, Belgium.
,
B. de HemptinneDepartment of Abdominal Surgery, Ghent University Hospital, Ghent University, Belgium.
&
P. PattynDepartment of Abdominal Surgery, Ghent University Hospital, Ghent University, Belgium.
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Pages 309-314 | Published online: 14 Mar 2016

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Murat Ulas, Ilter Ozer, Metin Ercan, Yusuf B. Ozogul, E. Birol Bostanci, Tulay Temucin Keklik, Ummuhani Ozel Turkcu, Ayse Bilgihan & Musa Akoglu. (2009) Effects of CO2 Pneumoperitoneum on Anastomotic Healing in Rats Receiving Preoperative 5-Fluorouracil Neoadjuvant Chemotherapy. Journal of Investigative Surgery 22:6, pages 413-418.
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Articles from other publishers (13)

H.-H. Cheng, Y.-C. Shao, C.-Y. Lin, T.-W. Chiang, M.-C. Chen, T.-Y. Chiu, Y.-L. Huang, C.-C. Chen, C.-P. Chen & F.-F. Chiang. (2023) Impact of chemotherapy on surgical outcomes in ileostomy reversal: a propensity score matching study from a single centre. Techniques in Coloproctology 27:12, pages 1227-1234.
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Motoi Koyama, Akihiko Murata, Yoshiyuki Sakamoto, Hajime Morohashi, Tatsuya Hasebe, Takeshi Saito & Kenichi Hakamada. (2015) Risk Factors for Anastomotic Leakage After Intersphincteric Resection Without a Protective Defunctioning Stoma for Lower Rectal Cancer. Annals of Surgical Oncology 23:S2, pages 249-256.
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Yahya Ekici, Eda Yılmaz Akcay & Gokhan Moray. (2015) Effect of the Bioadhesive, BioGlue, on Impaired Colonic Anastomose Healing in Rats. International Surgery 100:11-12, pages 1375-1381.
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Sheng Li, Yong-lei Zhang, Jia-yuan Sun, Ya-wei Hua & Pei-hong Wu. (2013) Safe temperature range for intraoperative and early postoperative continuous hyperthermic intraperitoneal perfusion in a swine model of experimental distal gastrectomy with Billroth II reconstruction. Journal of Translational Medicine 11:1.
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G M de Jong, R P Bleichrodt, A Eek, W J G Oyen, O C Boerman & T Hendriks. (2011) Experimental study of radioimmunotherapy versus chemotherapy for colorectal cancer . British Journal of Surgery 98:3, pages 436-441.
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Mehmet Uludag, Kursat Ozdilli, Bulent Citgez, Gurkan Yetkin, Osman M. Ipcioglu, Omer Ozcan, Nedim Polat, Abdulcabbar Kartal, Pinar Torun & Adnan Isgor. (2009) Covering the colon anastomoses with amniotic membrane prevents the negative effects of early intraperitoneal 5-FU administration on anastomotic healing. International Journal of Colorectal Disease 25:2, pages 223-232.
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E. A. Rieff, T. Hendriks, H. J. T. Rutten, G. A. P. Nieuwenhuijzen, M. J. E. M. Gosens, A. J. C. van den Brule, S. W. Nienhuijs & I. H. J. T. de Hingh. (2009) Neoadjuvant Radiochemotherapy Increases Matrix Metalloproteinase Activity in Healthy Tissue in Esophageal Cancer Patients. Annals of Surgical Oncology 16:5, pages 1384-1389.
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Jung Wook Huh, Yoon Ah Park & Seung Kook Sohn. (2007) A Diverting Stoma Is Not Necessary when Performing a Handsewn Coloanal Anastomosis for Lower Rectal Cancer. Diseases of the Colon & Rectum 50:7, pages 1040-1046.
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J. O. W. Pelz, J. Doerfer, M. Decker, A. Dimmler, W. Hohenberger & T. Meyer. (2007) Hyperthermic intraperitoneal chemoperfusion (HIPEC) decrease wound strength of colonic anastomosis in a rat model. International Journal of Colorectal Disease 22:8, pages 941-947.
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K. Vasiliadis, M. G. Pramateftakis, K. Blouhos, I. Mantzoros, G. Koliakos, T. Zaraboukas, I. Kanellos, H. Demetriades, D. H. Alamdari & D. Betsis. (2007) Effect of Iloprost on Impaired Anastomotic Healing Caused by 5-Fluorouracil plus Leucovorin. Diseases of the Colon & Rectum 50:6, pages 899-907.
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Harilaos D. Konstantinidis, Aristedis P. Slavakis, Konstantinos D. Ballas, Antonia C. Sioga, Louise D. Economou, Charalampos I. Demertzidis, Theano T. Pissanidou, Zoi S. Athanasiadou & Athanasios K. Sakadamis. (2007) The Effect of Capecitabine on the Healing of Colonic Anastomoses in Rats. Diseases of the Colon & Rectum 50:1, pages 89-96.
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I Gastinger, F Marusch, R Steinert, S Wolff, F Koeckerling & H Lippert. (2005) Protective defunctioning stoma in low anterior resection for rectal carcinoma. British Journal of Surgery 92:9, pages 1137-1142.
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G-Y. Chen, J.Y-Y. Lee & W-C. Chen. (2005) Sclerotic and retracted supravenous hyperpigmentation associated with combination chemotherapy for metastatic breast carcinoma. British Journal of Dermatology 152:6, pages 1383-1385.
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