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Original Article

Incorporation of vancomycin-supplemented bone allografts
Radiographical, histopathological and immunohistochemical study in pigs

, , , , &
Pages 505-513 | Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Eivind Witsø, Leif Persen, Pål Benum & Kåre Bergh. (2005) Cortical allograft as a vehicle for antibiotic delivery. Acta Orthopaedica 76:4, pages 481-486.
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Martin A Buttaro, Maria I Gimenez, Graciela Greco, Laura Barcan & Francisco Piccaluga. (2005) High active local levels of vancomycin without nephrotoxicity released from impacted bone allografts in 20 revision hip arthroplasties. Acta Orthopaedica 76:3, pages 336-340.
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Articles from other publishers (30)

Dimitrios Sotiriou, Hampus Stigbrand & Gösta Ullmark. (2020) Is two-stage revision surgery for infected hip arthroplasty worth the suffering, resources and results compared to one-stage?. HIP International 32:2, pages 205-212.
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Marco Govoni, Erwin P. Lamparelli, Maria C. Ciardulli, Antonietta Santoro, Antonio Oliviero, Ida Palazzo, Ernesto Reverchon, Leonardo Vivarelli, Alessandra Maso, Elisa Storni, Maria E. Donati, Gianluca Ruspaggiari, Nicola Maffulli, Milena Fini, Giovanna Della Porta & Dante Dallari. (2020) Demineralized bone matrix paste formulated with biomimetic PLGA microcarriers for the vancomycin hydrochloride controlled delivery: Release profile, citotoxicity and efficacy against S. aureus. International Journal of Pharmaceutics 582, pages 119322.
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Arne Peeters, Guy Putzeys & Lieven Thorrez. (2019) Current Insights in the Application of Bone Grafts for Local Antibiotic Delivery in Bone Reconstruction Surgery. Journal of Bone and Joint Infection 4:5, pages 245-253.
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L. Frommelt. (2017) Anwendung von Antibiotika im KnochenUse of antibiotics in bones. Der Orthopäde 47:1, pages 24-29.
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Marianne Parent, Amandine Magnaudeix, Sylvie Delebassée, Elisabeth Sarre, Eric Champion, Marylène Viana Trecant & Chantal Damia. (2016) Hydroxyapatite microporous bioceramics as vancomycin reservoir: Antibacterial efficiency and biocompatibility investigation. Journal of Biomaterials Applications 31:4, pages 488-498.
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Javad Parvizi, Mohammad Ghazavi & Members of Pre-Op Antibiotics Committee of the Consensus Meeting. (2016) Antibiotic Prophylaxis in Periprosthetic Joint Infection (PJI): Literature Review and World Consensus (Part Six). Shafa Orthopedic Journal In Press:In Press.
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Débora Coraça-Huber, Johann Hausdorfer, Manfred Fille, Michael Nogler & Klaus-Dieter Kühn. (2014) Calcium Carbonate Powder Containing Gentamicin for Mixing With Bone Grafts. Orthopedics 37:8.
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Débora C. Coraça-Huber, Alexander Wurm, Manfred Fille, Johann Hausdorfer, Michael Nogler & Klaus-Dieter Kühn. (2014) Effect of freezing on the release rate of gentamicin palmitate and gentamicin sulfate from bone tissue. Journal of Orthopaedic Research 32:6, pages 842-847.
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Débora C. Coraça-Huber, David Putzer, Manfred Fille, Johann Hausdorfer, Michael Nogler & Klaus-Dieter Kühn. (2013) Gentamicin palmitate as a new antibiotic formulation for mixing with bone tissue and local release. Cell and Tissue Banking 15:1, pages 139-144.
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Erik Hansen, Katherine Belden, Randi Silibovsky, Markus Vogt, William V. Arnold, Goran Bicanic, Stefano A. Bini, Fabio Catani, Jiying Chen, Mohammad T. Ghazavi, Karine M. Godefroy, Paul Holham, Hamid Hosseinzadeh, Kang I.I. Kim, Klaus Kirketerp-Møller, Lars Lidgren, Jian Hao Lin, Jess H. Lonner, Christopher C. Moore, Panayiotis Papagelopoulos, Lazaros Poultsides, R. Lor Randall, Brian Roslund, Khalid Saleh, Julia V. Salmon, Edward M. Schwarz, Jose Stuyck, Annette W. Dahl & Koji Yamada. (2014) Perioperative Antibiotics. The Journal of Arthroplasty 29:2, pages 29-48.
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. (2014) Perioperative Antibiotics. Journal of Orthopaedic Research 32:S1, pages S31-S59.
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Amanda E. Brooks, Benjamin D. Brooks, Sherry N. Davidoff, Paul C. Hogrebe, Mark A. Fisher & David W. Grainger. (2013) Polymer-controlled release of tobramycin from bone graft void filler. Drug Delivery and Translational Research 3:6, pages 518-530.
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D. C. Cora?a-Huber, J. Hausdorfer, M. Fille & M. Nogler. (2012) Effect of storage temperature on gentamicin release from antibiotic-coated bone chips. Cell and Tissue Banking 14:3, pages 395-400.
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D. C. Coraça-Huber, J. Hausdorfer, M. Fille, M. Steidl & M. Nogler. (2012) Effect of two cleaning processes for bone allografts on gentamicin impregnation and in vitro antibiotic release. Cell and Tissue Banking 14:2, pages 221-229.
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Nina MC Mathijssen, Gerjon Hannink, Peter Pilot, B Wim Schreurs, Rolf M Bloem & Pieter Buma. (2012) Impregnation of bone chips with alendronate and cefazolin, combined with demineralized bone matrix: a bone chamber study in goats. BMC Musculoskeletal Disorders 13:1.
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P. Melicherčík, D. Jahoda, O. Nyč, E. Klapková, V. Barták, I. Landor, D. Pokorný, T. Judl & A. Sosna. (2012) Bone grafts as vancomycin carriers in local therapy of resistant infections. Folia Microbiologica 57:5, pages 459-462.
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Martin A. Buttaro. (2012) Bone Grafting and Two-Stage Revision Total Hip Arthroplasty. HIP International 22:8_suppl, pages 69-74.
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Konstantinos Anagnostakos & Katrin Schr?der. (2012) Antibiotic-Impregnated Bone Grafts in Orthopaedic and Trauma Surgery: A Systematic Review of the Literature. International Journal of Biomaterials 2012, pages 1-9.
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N.J. Hickok, C. Ketonis & C.S. Adams. 2011. Comprehensive Biomaterials. Comprehensive Biomaterials 281 294 .
Nina MC Mathijssen, Pieter LC Petit, Peter Pilot, B Wim Schreurs, Pieter Buma & Rolf M Bloem. (2010) Impregnation of bone chips with antibiotics and storage of antibiotics at different temperatures: an in vitro study. BMC Musculoskeletal Disorders 11:1.
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P. MELICHERČÍK, D. JAHODA, V. BARTÁK, E. KLAPKOVÁ, O. NYČ, D. POKORNÝ, I. Landor, A. Sosna & T. Judl. (2010) In Vitro Assessment of Vancomycin Released from Bone Grafts. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 77:5, pages 411-415.
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Martin A. Buttaro, Agustin J. Guala, Fernando Comba, Federico Suarez & Francisco Piccaluga. (2018) Incidence of Deep Infection in Aseptic Revision THA using Vancomycin-Impregnated Impacted Bone Allograft. HIP International 20:4, pages 535-541.
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Battugs Borkhuu, Andrzej Borowski, Suken A. Shah, Aaron G. Littleton, Kirk W. Dabney & Freeman Miller. (2008) Antibiotic-Loaded Allograft Decreases the Rate of Acute Deep Wound Infection After Spinal Fusion in Cerebral Palsy. Spine 33:21, pages 2300-2304.
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M. ButtaroG. S. AraujoE. S. AraujoF. CombaF. Piccaluga. (2008) Viability of impacted bone allografts under metal mesh at the calcar in revision surgery of the hip. The Journal of Bone and Joint Surgery. British volume 90-B:2, pages 228-231.
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Martin Buttaro, Fernando Comba & Francisco Piccaluga. (2007) Vancomycin-supplemented Cancellous Bone Allografts in Hip Revision Surgery. Clinical Orthopaedics & Related Research 461, pages 74-80.
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E. Witsø. 2007. Infection and Local Treatment in Orthopedic Surgery. Infection and Local Treatment in Orthopedic Surgery 154 159 .
F. CombaM. ButtaroR. PussoF. Piccaluga. (2006) Acetabular reconstruction with impacted bone allografts and cemented acetabular components. The Journal of Bone and Joint Surgery. British volume 88-B:7, pages 865-869.
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Christopher Bibbo & Dipak V. Patel. (2016) The Effect of Demineralized Bone Matrix-Calcium Sulfate with Vancomycin on Calcaneal Fracture Healing and Infection Rates: A Prospective Study. Foot & Ankle International 27:7, pages 487-493.
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M. A. ButtaroA. MorandiH. Garcia RivelloF. Piccaluga. (2005) Histology of vancomycin-supplemented impacted bone allografts in revision total hip arthroplasty. The Journal of Bone and Joint Surgery. British volume 87-B:12, pages 1684-1687.
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M. A. ButtaroR. PussoF. Piccaluga. (2005) Vancomycin-supplemented impacted bone allografts in infected hip arthroplasty. The Journal of Bone and Joint Surgery. British volume 87-B:3, pages 314-319.
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