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Research Article

IL-13 Suppresses MUC5AC Gene Expression and Mucin Secretion in Nasal Epithelial Cells

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Pages 638-643 | Published online: 08 Jul 2009

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Read on this site (4)

Steve Cornick, Adelaide Tawiah & Kris Chadee. (2015) Roles and regulation of the mucus barrier in the gut. Tissue Barriers 3:1-2.
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Hyun-Jae Woo, Woo Jong Yoo, Chang Hoon Bae, Si-Youn Song, Yong-Woon Kim, So-Young Park & Yong-Dae Kim. (2010) Leptin up-regulates MUC5B expression in human airway epithelial cells via mitogen-activated protein kinase pathway. Experimental Lung Research 36:5, pages 262-269.
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I-Jong Wang, Chun-Yin Wu & Fung-Rong Hu. (2007) Effect of proinflammatory cytokines on the human MUC5AC promoter activity in vitro and in vivo. Clinical Ophthalmology 1:1, pages 71-77.
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Reen Wu, Richart Harper, Cheng-Yuan Kao, Philip Thai, Daphne Wu, Yin Chen & Mary M. J. Chang. (2006) New insights into airway mucous cell differentiation. Journal of Organ Dysfunction 2:1, pages 30-36.
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Articles from other publishers (20)

Hassan Melhem, Daniel Regan-Komito & Jan Hendrik Niess. (2021) Mucins Dynamics in Physiological and Pathological Conditions. International Journal of Molecular Sciences 22:24, pages 13642.
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Martin Schicht, Adrian Reichle, Mirco Schapher, Fabian Garreis, Benedikt Kleinsasser, Malik Aydin, Afsun Sahin, Heinrich Iro & Friedrich Paulsen. (2021) The Translational Role of MUC8 in Salivary Glands: A Potential Biomarker for Salivary Stone Disease?. Diagnostics 11:12, pages 2330.
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Yumin Kim, Soyoung Hwang, Roza Khalmuratova, Sunah Kang, Mingyu Lee, Youngjun Song, Jong-Wan Park, Jaehoon Yu, Hyun-Woo Shin & Yan Lee. (2020) α-Helical cell-penetrating peptide-mediated nasal delivery of resveratrol for inhibition of epithelial-to-mesenchymal transition. Journal of Controlled Release 317, pages 181-194.
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Chaonan Ma & Wei Ma. (2018) Plantamajoside Inhibits Lipopolysaccharide-Induced MUC5AC Expression and Inflammation through Suppressing the PI3K/Akt and NF-κB Signaling Pathways in Human Airway Epithelial Cells. Inflammation 41:3, pages 795-802.
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Surendran Thavagnanam, Jeremy C. Parker, Michael E. McBrien, Grzegorz Skibinski, Michael D Shields & Liam G. Heaney. (2014) Nasal Epithelial Cells Can Act as a Physiological Surrogate for Paediatric Asthma Studies. PLoS ONE 9:1, pages e85802.
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Paula J. Busse, Teng Fei Zhang, Brian Schofield, Saikiran Kilaru, Sangita Patil & Xiu-Min Li. (2009) Decrease in airway mucous gene expression caused by treatment with anti-tumor necrosis factor α in a murine model of allergic asthma. Annals of Allergy, Asthma & Immunology 103:4, pages 295-303.
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Paula J. Busse & John V. Fahy. 2009. Middleton's Allergy: Principles and Practice. Middleton's Allergy: Principles and Practice 659 677 .
George Theodoropoulos & Kermit L. Carraway. (2007) Molecular signaling in the regulation of mucins. Journal of Cellular Biochemistry 102:5, pages 1103-1116.
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Gautam Damera, Baoyun Xia & Goverdhan P Sachdev. (2006) IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling. Respiratory Research 7:1.
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Dong-Won Lee, Shawna A Shirley, Richard F Lockey & Shyam S Mohapatra. (2006) Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline. Respiratory Research 7:1.
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Mahefatiana Andrianifahanana, Nicolas Moniaux & Surinder K. Batra. (2006) Regulation of mucin expression: Mechanistic aspects and implications for cancer and inflammatory diseases. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1765:2, pages 189-222.
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Gautam Damera, Baoyun Xia, Hanumatha R. Ancha & Goverdhan P. Sachdev. (2006) IL-9 Modulated MUC4 Gene and Glycoprotein Expression in Airway Epithelial Cells . Bioscience Reports 26:1, pages 55-67.
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Mary Callaghan Rose & Judith A. Voynow. (2006) Respiratory Tract Mucin Genes and Mucin Glycoproteins in Health and Disease. Physiological Reviews 86:1, pages 245-278.
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Philip Thai, Yin Chen, Gregory Dolganov & Reen Wu. (2005) Differential Regulation of MUC5AC/Muc5ac and hCLCA-1/mGob-5 Expression in Airway Epithelium. American Journal of Respiratory Cell and Molecular Biology 33:6, pages 523-530.
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Douglas A. Kuperman, Xiaozhu Huang, Louis Nguyenvu, Christoph Hölscher, Frank Brombacher & David J. Erle. (2005) IL-4 Receptor Signaling in Clara Cells Is Required for Allergen-Induced Mucus Production. The Journal of Immunology 175:6, pages 3746-3752.
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Paul V. Beum, Hesham Basma, Dhundy R. Bastola & Pi-Wan Cheng. (2005) Mucin biosynthesis: upregulation of core 2 β1,6 N -acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line . American Journal of Physiology-Lung Cellular and Molecular Physiology 288:1, pages L116-L124.
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Michael E Johnson & Paul J Murphy. (2004) Changes in the tear film and ocular surface from dry eye syndrome. Progress in Retinal and Eye Research 23:4, pages 449-474.
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Hazel C. Atherton, Gareth Jones & Henry Danahay. (2003) IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation. American Journal of Physiology-Lung Cellular and Molecular Physiology 285:3, pages L730-L739.
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Yin Chen, Philip Thai, Yu-Hua Zhao, Ye-Shih Ho, Mary M. DeSouza & Reen Wu. (2003) Stimulation of Airway Mucin Gene Expression by Interleukin (IL)-17 through IL-6 Paracrine/Autocrine Loop. Journal of Biological Chemistry 278:19, pages 17036-17043.
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Juan Perez-Vilar, John K. Sheehan & Scott H. Randell. (2003) Making More MUCS. American Journal of Respiratory Cell and Molecular Biology 28:3, pages 267-270.
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