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Acta Oto-Laryngologica Volume 128, 2008 - Issue 3
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ORIGINAL ARTICLE

Comparisons of cochleotoxicity among three gentamicin compounds following intratympanic application

Masamichi Kobayashi Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Japan; Department of Clinical Science, Otorhinolaryngology, University Hospital of Umeå, Sweden
,
Michihiko Sone Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, JapanCorrespondence[email protected]
, MD,
Masayuki Umemura Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University School of Medicine, Japan
,
Toshitaka Nabeshima Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University School of Medicine, Japan
,
Tsutomu Nakashima Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Japan
&
Sten Hellström Department of Audiology, Karolinska University Hospital, Stockholm, Sweden
Pages 245-249 | Received 25 May 2007, Published online: 08 Jul 2009

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Hirokazu Tanaka, Tohru Tanigawa, Mamoru Suzuki, Koji Otsuka & Shigeru Inafuku. (2010) Effects of MRI contrast agents (Omniscan™) on vestibular end organs. Acta Oto-Laryngologica 130:1, pages 17-24.
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Ance Bārzdiņa, Aiva Plotniece, Arkadij Sobolev, Karlis Pajuste, Dace Bandere & Agnese Brangule. (2024) From Polymeric Nanoformulations to Polyphenols—Strategies for Enhancing the Efficacy and Drug Delivery of Gentamicin. Antibiotics 13:4, pages 305.
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Jonathan Parra, Ainsley Beaton, Ryan F Seipke, Barrie Wilkinson, Matthew I Hutchings & Katherine R Duncan. (2023) Antibiotics from rare actinomycetes, beyond the genus Streptomyces. Current Opinion in Microbiology 76, pages 102385.
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Santanu Jana, Parasuraman Rajasekaran, Klara Haldimann, Andrea Vasella, Erik C. Böttger, Sven N. Hobbie & David Crich. (2023) Synthesis of Gentamicins C1, C2, and C2a and Antiribosomal and Antibacterial Activity of Gentamicins B1, C1, C1a, C2, C2a, C2b, and X2. ACS Infectious Diseases 9:8, pages 1622-1633.
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Mary E. O’Sullivan, Yohan SongRobert GreenhouseRandy LinAdela PerezPatrick J. AtkinsonJacob P. MacDonaldZehra SiddiquiDennis LagascaKate ComstockMarkus E. Huth, Alan G. Cheng & Anthony J. Ricci. (2020) Dissociating antibacterial from ototoxic effects of gentamicin C-subtypes. Proceedings of the National Academy of Sciences 117:51, pages 32423-32432.
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Alec W. Gibson, Il Joon Moon, Justin S. Golub & Jay T. Rubinstein. (2019) A comparison of endolymphatic shunt surgery and intratympanic gentamicin for meniere's disease. The Laryngoscope 130:10, pages 2455-2460.
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Moriah Jospe-Kaufman, Liza Siomin & Micha Fridman. (2020) The relationship between the structure and toxicity of aminoglycoside antibiotics. Bioorganic & Medicinal Chemistry Letters 30:13, pages 127218.
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Xin Xie, Jia-Wei Zhu, Yi Liu & Hui Jiang. (2020) Application of Genetic Engineering Approaches to Improve Bacterial Metabolite Production. Current Protein & Peptide Science 21:5, pages 488-496.
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Zeng Wei, Xianai Shi, Rong Lian, Weibin Wang, Wenrong Hong & Shaobin Guo. (2019) Exclusive Production of Gentamicin C1a from Micromonospora purpurea by Metabolic Engineering. Antibiotics 8:4, pages 267.
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Masaaki Ishikawa, Nadia García-Mateo, Alen Čusak, Iris López-Hernández, Marta Fernández-Martínez, Marcus Müller, Lukas Rüttiger, Wibke Singer, Hubert Löwenheim, Gregor Kosec, Štefan Fujs, Luis Martínez-Martínez, Thomas Schimmang, Hrvoje Petković, Marlies Knipper & M. Beatriz Durán-Alonso. (2019) Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use. Scientific Reports 9:1.
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Sicong LiJunhong GuoAnna RevaFanglu HuangBinbin XiongYuanzhen LiuZixin Deng, Peter F. LeadlayYuhui Sun. (2018) Methyltransferases of gentamicin biosynthesis. Proceedings of the National Academy of Sciences 115:6, pages 1340-1345.
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Rose Richardson, Matthew Smart, Dhani Tracey-White, Andrew R. Webster & Mariya Moosajee. (2017) Mechanism and evidence of nonsense suppression therapy for genetic eye disorders. Experimental Eye Research 155, pages 24-37.
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Yi Yu, Qi Zhang & Zixin Deng. (2017) Parallel pathways in the biosynthesis of aminoglycoside antibiotics. F1000Research 6, pages 723.
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Chuan Huang, Fanglu Huang, Eileen Moison, Junhong Guo, Xinyun Jian, Xiaobo Duan, Zixin Deng, Peter F. Leadlay & Yuhui Sun. (2015) Delineating the Biosynthesis of Gentamicin X2, the Common Precursor of the Gentamicin C Antibiotic Complex. Chemistry & Biology 22:2, pages 251-261.
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Junhong Guo, Fanglu Huang, Chuan Huang, Xiaobo Duan, Xinyun Jian, Finian Leeper, Zixin Deng, Peter F. Leadlay & Yuhui Sun. (2014) Specificity and Promiscuity at the Branch Point in Gentamicin Biosynthesis. Chemistry & Biology 21:5, pages 608-618.
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Koichi Inoue, Yasuko Hattori, Masakazu Horie, Tomoaki Hino & Hisao Oka. (2011) Preparative purification of gentamicin components using high‐speed counter‐current chromatography coupled with electrospray mass spectrometry. Journal of Separation Science 34:12, pages 1484-1488.
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