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Acta Oto-Laryngologica Volume 128, 2008 - Issue 6
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ORIGINAL ARTICLE

HOX-GFP and WOX-GFP lentivirus vectors for inner ear gene transfer

Laura Pietola Department of Otorhinolaryngology, Helsinki University Central Hospital, Helsinki
,
Antti A. Aarnisalo Department of Otorhinolaryngology, Helsinki University Central Hospital, Helsinki
,
Joonas Joensuu Department of Otorhinolaryngology, Helsinki University Central Hospital, Helsinki
,
Riikka Pellinen Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland
,
Jarmo Wahlfors Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland
&
Jussi Jero Department of Otorhinolaryngology, Helsinki University Central Hospital, HelsinkiCorrespondence[email protected]
, MD
Pages 613-620 | Received 06 Jun 2007, Published online: 08 Jul 2009

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Hildegard Büning, Axel Schambach, Michael Morgan, Axel Rossi, Helena Wichova, Hinrich Staecker, Athanasia Warnecke & Thomas Lenarz. (2020) Challenges and advances in translating gene therapy for hearing disorders. Expert Review of Precision Medicine and Drug Development 5:1, pages 23-34.
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Articles from other publishers (27)

Larissa Nassauer, Hinrich Staecker, Peixin Huang, Bryan Renslo, Madeleine Goblet, Jennifer Harre, Athanasia Warnecke, Juliane W. Schott, Michael Morgan, Melanie Galla & Axel Schambach. (2024) Protection from cisplatin-induced hearing loss with lentiviral vector-mediated ectopic expression of the anti-apoptotic protein BCL-XL. Molecular Therapy - Nucleic Acids 35:1, pages 102157.
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Kübra Kelleci & Eda Golebetmaz. (2023) Regenerative Therapy Approaches and Encountered Problems in Sensorineural Hearing Loss. Current Stem Cell Research & Therapy 18:2, pages 186-201.
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Steven A. Gordon & Richard K. Gurgel. (2021) Past and Future Biologics for Otologic Disorders. Otolaryngologic Clinics of North America 54:4, pages 779-787.
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Gina Na & Jinsei Jung. (2021) Diagnosis and Intervention of Genetic Hearing Loss. Journal of Clinical Otolaryngology Head and Neck Surgery 32:1, pages 5-19.
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Jin Woong Choi. (2021) Inner Ear Gene Therapy in Mouse Models of Genetic Hearing Loss. Korean Journal of Otorhinolaryngology-Head and Neck Surgery 64:4, pages 215-222.
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Evan M. de Joya, Brett M. Colbert, Pei-Ciao Tang, Byron L. Lam, Jun Yang, Susan H. Blanton, Derek M. Dykxhoorn & Xuezhong Liu. (2021) Usher Syndrome in the Inner Ear: Etiologies and Advances in Gene Therapy. International Journal of Molecular Sciences 22:8, pages 3910.
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Justine M. Renauld & Martin L. Basch. (2021) Congenital Deafness and Recent Advances Towards Restoring Hearing Loss. Current Protocols 1:3.
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Ning Ding, Sangsin Lee, Matan Lieber-Kotz, Jie Yang & Xue Gao. (2021) Advances in genome editing for genetic hearing loss. Advanced Drug Delivery Reviews 168, pages 118-133.
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Alaa Koleilat, Colin L. W. Driscoll, Lisa A. Schimmenti & Gayla L. Poling. (2020) Emerging Therapies and Approaches to Treat and Prevent Hearing Loss. Perspectives of the ASHA Special Interest Groups 5:5, pages 1147-1165.
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Sungsu Lee, Anna Dondzillo, Samuel P. Gubbels & Yehoash Raphael. (2020) Practical aspects of inner ear gene delivery for research and clinical applications. Hearing Research 394, pages 107934.
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Gwenaelle G.S. Géléoc & Aziz El-Amraoui. (2020) Disease mechanisms and gene therapy for Usher syndrome. Hearing Research 394, pages 107932.
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Michael Morgan, Juliane W. Schott, Axel Rossi, Christian Landgraf, Athanasia Warnecke, Hinrich Staecker, Anke Lesinski-Schiedat, Brigitte Schlegelberger, Hildegard Büning, Bernd Auber & Axel Schambach. (2020) Gene therapy as a possible option to treat hereditary hearing loss. Medizinische Genetik 32:2, pages 149-159.
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Sedigheh Delmaghani & Aziz El-Amraoui. (2020) Inner Ear Gene Therapies Take Off: Current Promises and Future Challenges. Journal of Clinical Medicine 9:7, pages 2309.
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Sonja Kleinlogel, Christian Vogl, Marcus Jeschke, Jakob Neef & Tobias Moser. (2020) Emerging approaches for restoration of hearing and vision. Physiological Reviews.
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Shahar Taiber & Karen B. Avraham. (2019) Genetic Therapies for Hearing Loss: Accomplishments and Remaining Challenges. Neuroscience Letters 713, pages 134527.
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Yin Ren, Lukas D. Landegger & Konstantina M. Stankovic. (2019) Gene Therapy for Human Sensorineural Hearing Loss. Frontiers in Cellular Neuroscience 13.
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Nathanial T Carpena & Min Young Lee. (2018) Genetic Hearing Loss and Gene Therapy. Genomics & Informatics 16:4, pages e20.
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Hena Ahmed, Olga Shubina-Oleinik & Jeffrey R. Holt. (2017) Emerging Gene Therapies for Genetic Hearing Loss. Journal of the Association for Research in Otolaryngology 18:5, pages 649-670.
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Ye Wang, Li Qiao, Yang Chen, Liting Wen, Bo Yue, Jianhua Qiu & Shengxi Wu. (2015) Establishment of a model of cochlear lesions in rats to study potential gene therapy for sensorineural hearing loss. International Journal of Pediatric Otorhinolaryngology 79:12, pages 2147-2154.
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X Chen, X Zhao, Y Hu, F Lan, H Sun, G Fan, Y Sun, J Wu, W Kong & W Kong. (2015) The spread of adenoviral vectors to central nervous system through pathway of cochlea in mimetic aging and young rats. Gene Therapy 22:11, pages 866-875.
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Yu Han, Liu Hong, Cuiping Zhong & Jianhua Qiu. (2015) Construction of recombinant adenoviral vector carrying <i>cyclinA2</i> gene. Drug Discoveries & Therapeutics 9:1, pages 66-69.
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Q Yu, Y Wang, Q Chang, J Wang, S Gong, H Li & X Lin. (2013) Virally expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice. Gene Therapy 21:1, pages 71-80.
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Juan C. Maass, F. Andrés Berndt, José Cánovas & Manuel Kukuljan. (2013) p27Kip1 Knockdown Induces Proliferation in the Organ of Corti in Culture after Efficient shRNA Lentiviral Transduction. Journal of the Association for Research in Otolaryngology 14:4, pages 495-508.
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Yan Wei, Yong Fu, Shaosheng Liu, GuiHua Xia & Song Pan. (2013) Effect of lentiviruses carrying enhanced green fluorescent protein injected into the scala media through a cochleostomy in rats. American Journal of Otolaryngology 34:4, pages 301-307.
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R Sacheli, L Delacroix, P Vandenackerveken, L Nguyen & B Malgrange. (2012) Gene transfer in inner ear cells: a challenging race. Gene Therapy 20:3, pages 237-247.
Crossref
Yunfeng Wang, Yu Sun, Qing Chang, Shoeb Ahmad, Binfei Zhou, Yeunjung Kim, Huawei Li & Xi Lin. (2013) Early postnatal virus inoculation into the scala media achieved extensive expression of exogenous green fluorescent protein in the inner ear and preserved auditory brainstem response thresholds. The Journal of Gene Medicine 15:3-4, pages 123-133.
Crossref
Laura Pietola. (2012) Effects of p27 Kip1 - and p53- shRNAs on kanamycin damaged mouse cochlea . World Journal of Otorhinolaryngology 2:1, pages 1.
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