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Acta Oto-Laryngologica Volume 129, 2009 - Issue 10
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MOUTH/PHARYNX

A zinc-containing compound, Polaprezinc, is effective for patients with taste disorders: randomized, double-blind, placebo-controlled, multi-center study

Masafumi Sakagami Department of Otolaryngology, Hyogo College of Medicine, Hyogo, JapanCorrespondence[email protected]
,
Minoru Ikeda Department of Otolaryngology, Nihon University School of Medicine, Tokyo, Japan
,
Hiroshi Tomita Department of Otolaryngology, Nihon University School of Medicine, Tokyo, Japan
,
Akihiro Ikui Department of Otolaryngology, Nihon University School of Medicine, Tokyo, Japan
,
Tsunemasa Aiba Division of Otolaryngology, Osaka City General Hospital, Osaka, Japan
,
Noriaki Takeda Department of Otolaryngology, Tokushima University School of Medicine, Tokushima, Japan
,
Akira Inokuchi Department of Otolaryngology, Saga University Faculty of Medicine, Saga, Japan
,
Yuichi Kurono Department of Otolaryngology, Kagoshima University Faculty of Medicine, Kagoshima, Japan
,
Mitsuyoshi Nakashima Department of Pharmacology, Hamamatsu University School of Medicine, Shizuoka, Japan
,
Yuji Shibasaki Zeria Pharmaceutical Co. Ltd, Tokyo, Japan
&
Osamu Yotsuya Zeria Pharmaceutical Co. Ltd, Tokyo, Japan
 show all
Pages 1115-1120 | Received 20 Aug 2008, Published online: 19 Sep 2009

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Xue Gao, Mohammed A Al-Baadani, Minjie Wu, Ningyang Tong, Xinkun Shen, Xi Ding & Jinsong Liu. (2022) Study on the Local Anti-Osteoporosis Effect of Polaprezinc-Loaded Antioxidant Electrospun Membrane. International Journal of Nanomedicine 17, pages 17-29.
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Theng Choon Ooi, Kok Meng Chan & Razinah Sharif. (2017) Antioxidant, Anti-inflammatory, and Genomic Stability Enhancement Effects of Zinc l-carnosine: A Potential Cancer Chemopreventive Agent?. Nutrition and Cancer 69:2, pages 201-210.
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Atsuo Ikeda, Hiroki Sekine, Kyoichi Takao & Minoru Ikeda. (2013) Expression and localization of taste receptor genes in the vallate papillae of rats: effect of zinc deficiency. Acta Oto-Laryngologica 133:9, pages 957-964.
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Tomomi Nin & Kenzo Tsuzuki. (2023) Diagnosis and treatment of taste disorders in Japan. Auris Nasus Larynx.
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Tomoaki Shintani, Kouji Ohta, Toshinori Ando, Yasutaka Hayashido, Souichi Yanamoto, Mikihito Kajiya & Hideki Shiba. (2023) Retrospective study on the therapeutic efficacy of zinc acetate hydrate administration to patients with hypozincemia-induced dysgeusia. BMC Oral Health 23:1.
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Boshra Mozaffar & Iskandar Idris. (2022) A Literature Review of Taste Change and Zinc Deficiency After Bariatric Surgery: Could There Be a Causal Link?. Obesity Surgery 33:1, pages 313-331.
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Mingru Li, Zhen Sun, Hong Zhang & Zhaoyang Liu. (2021) Recent advances on polaprezinc for medical use (Review). Experimental and Therapeutic Medicine 22:6.
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Yasuyuki Nomura, Teruo Toi, Minoru Ikeda, Atsuo Ikeda, Makoto Tanaka & Takeshi Oshima. (2020) Prognostic factors of recovery with medication in patients with taste disorders. PLOS ONE 15:10, pages e0237270.
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Makoto Tanaka. (2017) Taste Disturbance. Journal of Nihon University Medical Association 76:3, pages 153-155.
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Basile N. Landis & Naif H. Alotaibi. (2017) Les troubles du goût. Pratiques en nutrition 13:49, pages 14-17.
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Hiroyuki Yanagisawa, Toru Kawashima, Mai Miyazawa & Tadahiro Ohshiro. (2016) Validity of the copper/zinc ratio as a diagnostic marker for taste disorders associated with zinc deficiency. Journal of Trace Elements in Medicine and Biology 36, pages 80-83.
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MASAFUMI SAKAGAMI. (2012) . Nippon Jibiinkoka Gakkai Kaiho 115:1, pages 8-13.
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Mineo Takei. (2012) The Development of Polaprezinc Researchポラプレジンク研究の展開. YAKUGAKU ZASSHI 132:3, pages 271-277.
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Keiko Onoda, Ryoji Hirai, Kyoichi Takao, Shinichiro Kokubun & Minoru Ikeda. (2011) Patients with hypogeusia show changes in expression of T2R taste receptor genes in their tongues. The Laryngoscope 121:12, pages 2592-2597.
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B.N. Landis & T. Just. (2010) SchmeckstörungenTaste disorders. HNO 58:7, pages 650-655.
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