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Analytical Letters Volume 4, 1971 - Issue 12
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CLINICAL ANALYSIS AND ANALYTICAL BIOCHEMISTRY

Quantitative Determination of Nortriptyline And Desmethylnortriptyline In Human Plasma By Combined Gas Ciiromatography - Mass Spectrometry

Olof Borgå Department of Toxicology Swedish Medical Research Council and Department of Pharmacology, (Division of Clinical Pharmacology), Karolinska Institutet, 104 01, Stockholm 60, Sweden
,
Lena Palmér Department of Toxicology Swedish Medical Research Council and Department of Pharmacology, (Division of Clinical Pharmacology), Karolinska Institutet, 104 01, Stockholm 60, Sweden
,
Allan Linnarsson Department of Toxicology Swedish Medical Research Council and Department of Pharmacology, (Division of Clinical Pharmacology), Karolinska Institutet, 104 01, Stockholm 60, Sweden
&
Bo Holmstedt Department of Toxicology Swedish Medical Research Council and Department of Pharmacology, (Division of Clinical Pharmacology), Karolinska Institutet, 104 01, Stockholm 60, Sweden
Pages 837-849 | Received 22 Sep 1971, Accepted 27 Sep 1971, Published online: 05 Dec 2006

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N. Narasimhachari & RobertO. Friedel. (1979) N-Alkylation of Secondary Amine Tricyclic Antidepressants as a General Method for Their Quantitation by GC-MS-SIM Technique. Preparation of N-Ethyl Derivatives of Desimipramine, Nortriptyline, Protiptyline and Desmethyldoxepin. Analytical Letters 12:1, pages 77-88.
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Roy Carrington & Alberto Frigerio. (1977) Mass Fragmentography in Drug Research. Drug Metabolism Reviews 6:2, pages 243-282.
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FredC. Falkner, BrianJ. Sweetman & J. Throck Watson. (1975) Biomedical Applications of Selected Ion Monitoring. Applied Spectroscopy Reviews 10:1, pages 51-116.
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Christos Tsaconas, Prudent Padieu, Philippe d'Athis, Elizabeth Mocaer & Norbert Bromet. (1989) Gas chromatographic-mass spectrometric assessment of the pharmacokinetics of amineptine and its main metabolite in volunteers with liver impairment. Journal of Chromatography B: Biomedical Sciences and Applications 487, pages 313-329.
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Joseph F. Sayegh. (1986) A simplified radioimmunoassay of plasma nortriptyline in depressed patients compared with high-pressure liquid chromatography and gas-liquid chromatography. Neurochemical Research 11:2, pages 193-206.
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J.Cymerman Craig, Larry D Gruenke & Trong-Lang Nguyen. (1982) Simultaneous analysis of imipramine and its metabolite desipramine in biological fluids. Journal of Chromatography A 239, pages 81-86.
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J.W. Hubbard, K.K. Midha, J.K. Cooper & C. Charette. (1978) Radioimmunoassay for Psychotropic Drugs II: Synthesis and Properties of Haptens for Tricyclic Antidepressants. Journal of Pharmaceutical Sciences 67:11, pages 1571-1578.
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E. Roseland Klein & Peter D. Klein. (1978) A selected bibliography of biomedical and environmental applications of stable isotopes. I—Deuterium 1971-1976. Biological Mass Spectrometry 5:2, pages 91-111.
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Rand G. Jenkins & Robert O. Friedel. (1978) Analysis of Tricyclic Antidepressants in Human Plasma by GLC–Chemical-Ionization Mass Spectrometry with Selected Ion Monitoring. Journal of Pharmaceutical Sciences 67:1, pages 17-23.
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Ian D. Watson & Michael J. Stewart. (1977) Quantitative determination of amitriptyline and nortriptyline in plasma by high-performance liquid chromatography. Journal of Chromatography A 132:1, pages 155-159.
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BRUCE A. SCOGGINS & KAY P. MAGUIRE. 1977. Handbook of Studies on Depression. Handbook of Studies on Depression 157 171 .
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W.A. Garland. (1977) Quantitative Determination of Amitriptyline and Its Principal Metabolite, Nortriptyline, by GLC‐Chemical Ionization Mass Spectrometry. Journal of Pharmaceutical Sciences 66:1, pages 77-81.
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M. Claeys, G. Muscettola & S. P. Markey. (1976) Simultaneous measurement of imipramine and desipramine by selected ion recording with deuterated internal standards. Biological Mass Spectrometry 3:3, pages 110-116.
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Michael G. Lee & Brian J. Millard. (1975) A comparison of unlabelled and labelled internal standards for quantification by single and multiple ion monitoring. Biological Mass Spectrometry 2:2, pages 78-81.
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L. D. Gruenke, J. Cymerman Craig & D. M. Bier. (1974) Multiple ion detection by accelerating voltage alternation in conjunction with voltage sweeping. Biological Mass Spectrometry 1:6, pages 418-422.
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D.B. Faber, C. Mulder & W.A. Man in 't Veld. (1974) A thin-layer method for the determination of amitriptyline and nortriptyline in plasma. Journal of Chromatography A 100:1, pages 55-61.
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G. Spiteller & G. Remberg. (1974) Arzneimittelstoffwechseluntersuchungen mit der Massenspektrometrie. Die Naturwissenschaften 61:11, pages 491-499.
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Marie Åsberg. (1974) Individualization of Treatment with Tricyclic Compounds. Medical Clinics of North America 58:5, pages 1083-1091.
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Jørgen Næstof & Niels-Erik Larsen. (1974) Quantitative determination of clonazepam and its metabolites in human plasma by gas chromatography. Journal of Chromatography A 93:1, pages 113-122.
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E.C. HORNING, M.G. HORNING & R.N. STILLWELL. 1974. Advances in Biomedical Engineering. Advances in Biomedical Engineering 1 74 .
S. Archer, S. G. Browne, K. M. Cahill, M. J. Colbourne, D. K. Dastur, Y. Ramamohan, A. S. Dabholkar, A. E. deSa, M. D. Deshmukh, K. G. Kulkarni, S. S. Virdi, E. F. Elslager, F. Hawking, P. A. J. Janssen, B. H. Kean, F. Kradolfer, M. J. Miller, A. N. D. Nanavati, V. N. Rao, R. Rott, M. Sasa, M. V. Sant, W. N. Gatlewar, T. U. K. Menon, C. E. G. Smith, E. A. Steck, B. J. Vakil, N. J. Dalal, D. M. Aviado & G. HorváthGyula Horváth. 1974. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques 399 473 .
Bo Holmstedt & Jan-Erik Lindgren. 1974. Ciba Foundation Symposium 26 - The Poisoned Patient: The Role of the Laboratory. Ciba Foundation Symposium 26 - The Poisoned Patient: The Role of the Laboratory 105 124 .
B. Alexanderson. (1973) Prediction of steady-state plasma levels of nortriptyline from single oral dose kinetics: A study in twins. European Journal of Clinical Pharmacology 6:1, pages 44-53.
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B. Alexanderson, O. Borg� & G. Alv�n. (1973) The availability of orally administered nortriptyline. European Journal of Clinical Pharmacology 5:3, pages 181-185.
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B. Alexanderson & O. Borg�. (1973) Urinary excretion of nortriptyline and five of its metabolites in man after single and multiple oral doses. European Journal of Clinical Pharmacology 5:3, pages 174-180.
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Lena Palmér & Birgitta Kolmodin-Hedman. (1972) Improved quantitative gas chromatographic method for the analysis of small amounts of chlorinated hydrocarbon pesticies in human plasma. Journal of Chromatography A 74:1, pages 21-30.
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A.E. Gordon & A. Frigerio. (1972) Mass fragmentography as an application of gas-liquid chromatography—mass spectrometry in biological research. Journal of Chromatography A 73:2, pages 401-417.
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B. Alexanderson. (1972) Pharmacokinetics of desmethylimipramine and nortriptyline in man after single and multiple oral doses ? A cross-over study. European Journal of Clinical Pharmacology 5:1, pages 1-10.
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Olof Borg» & Mats Garle. (1972) A gas chromatographic method for the quantitative determination of nortriptyline and some of its metabolites in human plasma and urine. Journal of Chromatography A 68:1, pages 77-88.
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