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Analytical Letters Volume 6, 1973 - Issue 10
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ANALYTICAL BIOCHEMISTRY AND CLINICAL ANALYSIS

Simultaneous Determination of Tolbutamide and its Metabolites in Biological Fluids

S. B. Matin Department of Pharmacy, School of Pharmacy University of California, San Francisco, California, 94143, U.S.A.
&
M. Rowland Department of Pharmacy, School of Pharmacy University of California, San Francisco, California, 94143, U.S.A.
Pages 865-876 | Received 03 Aug 1973, Accepted 15 Aug 1973, Published online: 06 Dec 2006

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W. Emmett Braselton$suffix/text()$suffix/text(), HerbertC. Ashline & EdwinD. Bransome$suffix/text()$suffix/text(). (1975) Formation of Thermally Stable Derivatives for Determination of Tolbutmide and Chlorpropmide by Gas Chromatography. Analytical Letters 8:5, pages 301-313.
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J B HoustonM K Cassidy. (1982) Rate limiting steps in metabolite kinetics: formation of 5-acetylaminosalicylate after administration of 5-aminosalicylate. Journal of Pharmacy and Pharmacology 34:8, pages 536-538.
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Fátima Ortega, Antonio Quintana, Elena Suárez, John C. Lukas, Nerea Jauregizar, Leire de la Fuente, Maria Luisa Lucero, Ana Gonzalo, Aurelio Orjales & Rosario Calvo. (2005) Pharmacokinetic–Pharmacodynamic Modeling of the Hydroxy Lerisetron Metabolite L6-OH in Rats: An Integrated Parent–Metabolite Model. Pharmaceutical Research 22:11, pages 1769-1782.
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S. L. Ali, H. H. Blume & B. S. Schug. 1996. Oral Antidiabetics. Oral Antidiabetics 73 128 .
YS Krishnaiah, S Satyanarayana & D Visweswaram. (2012) Interaction between tolbutamide and ketoconazole in healthy subjects.. British Journal of Clinical Pharmacology 37:2, pages 205-207.
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John W. Ho & David E. Moody. (1993) Determination of tolbutamide hydroxylation in rat liver microsomes by high-performance liquid chromatography: Effect of psychoactive drugs on in vitro activity. Life Sciences 52:1, pages 21-28.
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A. K. Miller, J. Adir & R. E. Vestal. (1990) Excretion of tolbutamide metabolites in young and old subjects. European Journal of Clinical Pharmacology 38:5, pages 523-524.
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Katalin Csillag, László Vereczkey & Béla Gachályi. (1989) Simple high-performance liquid chromatographic method for the determination of tolbutamide and its metabolites in human plasma and urine using photodiode-array detection. Journal of Chromatography B: Biomedical Sciences and Applications 490, pages 355-363.
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Julie Keal, Creina Stockley & Andrew Somogyi. (1986) Simultaneous determination of tolbutamide and its hydroxy and carboxy metabolites in plasma and urine by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 378, pages 237-241.
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William L. Schary & Malcolm Rowland. (1983) Protein binding and hepatic clearance: Studies with tolbutamide, a drug of low intrinsic clearance, in the isolated perfused rat liver preparation. Journal of Pharmacokinetics and Biopharmaceutics 11:3, pages 225-243.
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Osamu Sugita, Yasufumi Sawada, Yuichi Sugiyama, Tatsuji Iga & Manabu Hanano. (1981) Prediction of drug-drug interaction from In vitro plasma protein binding and metabolism. Biochemical Pharmacology 30:24, pages 3347-3354.
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Wade J. Adams & D. Scott Krueger. (1979) Specific and Sensitive High‐Performance Liquid Chromatographic Determination of Glyburide. Journal of Pharmaceutical Sciences 68:9, pages 1138-1140.
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Aaron D. Kossoy & John L. Occolowitz. (1978) Mass spectrometry ofN-methylsulfonylureas. A re-examination. Biological Mass Spectrometry 5:2, pages 123-127.
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J.J. Thiessen & M. Rowland. (1977) Kinetics of Drug-Drug Interactions in Sheep: Tolbutarnide and Sulfadimethoxine. Journal of Pharmaceutical Sciences 66:8, pages 1063-1070.
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Robert J. Weinkam, Malcolm Rowland & Peter J. Meffin. (1977) Determination of phenylbutazone, tolbutamide and metabolites in plasma and urine using chemical ionization mass spectrometry. Biological Mass Spectrometry 4:1, pages 42-47.
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Dennis J. Weber. (1976) High‐Pressure Liquid Chromatographic Analysis of Tolbutamide in Serum. Journal of Pharmaceutical Sciences 65:10, pages 1502-1505.
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Shaikh B. Matin & James B. Knight. (1974) The use of solid probe chemical ionization mass spectrometry and gas chromatography-chemical ionization mass spectrometry in quantitation of drugs in biological fluids. Determination of tolbutamide and its metabolites in human plasma. Biological Mass Spectrometry 1:5, pages 323-328.
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