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Analytical Letters Volume 14, 1981 - Issue 10
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PHARMACEUTICAL ANALYSIS

Determination of Chlorpromazine and Its Sulfoxide and 7-Hydroxy Metabolites by Ion-Pair High Pressure Liquid Chromatography

D. Stevenson Wolfson Bioanalytical Unit, Robens Institute of Industrial and Environmental Health and Safety, University of Surrey, Guildford, GU2 5XH, U.R.
&
E. Reid Wolfson Bioanalytical Unit, Robens Institute of Industrial and Environmental Health and Safety, University of Surrey, Guildford, GU2 5XH, U.R.
Pages 741-761 | Received 30 Mar 1981, Accepted 02 May 1981, Published online: 05 Dec 2006

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AliA. Ensafi & E. Heydari. (2008) Determination of Some Phenothiazines Compounds in Pharmaceuticals and Human Body Fluid by Electrocatalytic Oxidation at a Glassy Carbon Electrode Using Methylene Blue as a Mediator. Analytical Letters 41:13, pages 2487-2502.
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Articles from other publishers (15)

Balamurugan Karuppaiah, Ramaraj Sukanya, Shen-Ming Chen, Prajakta R. Chavan, Raj Karthik, Mahmudul Hasan, Ahamed Milton & Jae-Jin Shim. (2024) Morphological and electrocatalytic studies on Ni2+ doped MnWO4 microflowers: A dual mode catalyst for the electrochemical sensor and supercapacitor application. Journal of Energy Storage 79, pages 110145.
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I. Jenisha Daisy Priscillal & Sea-Fue Wang. (2023) Highly sensitive amperometric determination of chlorpromazine hydrochloride in blood serum sample employing antimony vanadate nanospheres as electrode modifier. Microchemical Journal 187, pages 108396.
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Raj Karthik, Karuppaiah Balamurugan, Shen-Ming Chen, Ramaraj Sukanya, Prajakta R. Chavan, Van Quang Nguyen, Jae-Jin Shim & Carmel B. Breslin. (2022) Investigation of the electrocatalytic activity of bismuth-substituted pyrochlore Y2Sn2O7 for the voltammetry determination of the antipsychotic drug. Materials Today Chemistry 26, pages 101117.
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Karuppaiah Balamurugan, Raj Karthik, Shen-Ming Chen, Ramaraj Sukanya, Bhuvaneswari Thasma Subramanian, Valsala Madhavan Nair Biju, Jae-Jin Shim & Carmel B. Breslin. (2022) Heterostructures of mixed metal oxides (ZnMnO3/ZnO) synthesized by a wet-chemical approach and their application for the electrochemical detection of the drug chlorpromazine. Composites Part B: Engineering 236, pages 109822.
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Venkata Narayana Palakollu, Rajshekhar Karpoormath, Lei Wang, Jiao-Ning Tang & Chen Liu. (2020) A Versatile and Ultrasensitive Electrochemical Sensing Platform for Detection of Chlorpromazine Based on Nitrogen-Doped Carbon Dots/Cuprous Oxide Composite. Nanomaterials 10:8, pages 1513.
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Limei Zhang, Ju Qin, Qiang Yang, Siqi Wei & Rui Yang. (2019) Cost-effective and facile fluorescent probes for label-free recognition of chlorpromazine hydrochloride and logic gate operation. Journal of Photochemistry and Photobiology A: Chemistry 382, pages 111918.
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Subbiramaniyan Kubendhiran, Rajalakshmi Sakthivel, Shen-Ming Chen, Rajeshkumar Anbazhagan & Hsieh-Chih Tsai. (2019) A novel design and synthesis of ruthenium sulfide decorated activated graphite nanocomposite for the electrochemical determination of antipsychotic drug chlorpromazine. Composites Part B: Engineering 168, pages 282-290.
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Jeyaraj Vinoth Kumar, Raj Karthik, Shen-Ming Chen, Thangavelu Kokulnathan, Subramanian Sakthinathan, Velluchamy Muthuraj, Te-Wei Chiu & Tse-Wei Chen. (2018) Highly selective electrochemical detection of antipsychotic drug chlorpromazine in drug and human urine samples based on peas-like strontium molybdate as an electrocatalyst. Inorganic Chemistry Frontiers 5:3, pages 643-655.
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C. Pistos & James T. Stewart. (2003) Direct injection HPLC method for the determination of selected phenothiazines in plasma using a Hisep column. Biomedical Chromatography 17:7, pages 465-470.
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Ashraf H. Abadi, Syed Rafatullah & Abdullah A. Al-Badr. 1999. 97 165 .
K.K. Midha, G. McKay, B.S. Chakraborty, M. Young, E.M. Hawes, J.W. Hubbard, J.K. Cooper & E.D. Korchinski. (1990) Bioequivalence of two Thorazine Tablet Formulations Using Radioimmunoassay and Gas Chromatographic-mass Spectrometric Methods. Journal of Pharmaceutical Sciences 79:3, pages 196-201.
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T. Loennechen & S.G. Dahl. (1990) High-performance liquid chromatography of levomepromazine (methotrimeprazine) and its main metabolites. Journal of Chromatography A 503, pages 205-215.
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P. S. B. Minty. 1986. Analytical Methods in Human Toxicology. Analytical Methods in Human Toxicology 161 239 .
J.K. Cooper, G. Mckay & K.K. Midha. (1983) Subnanogram Quantitation of Chlorpromazine in Plasma by High-Performance Liquid Chromatography with Electrochemical Detection. Journal of Pharmaceutical Sciences 72:11, pages 1259-1262.
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G. McKay, K. Hall, J.K. Cooper, E.M. Hawes & K.K. Midha. (1982) Gas chromatographic—mass spectrometric procedure for the quantitation of chlorpromazine in plasma and its comparison with a new high-performance liquid chromatographic assay with electrochemical detection. Journal of Chromatography B: Biomedical Sciences and Applications 232:2, pages 275-282.
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