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Analytical Letters Volume 27, 1994 - Issue 3
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PHARMACEUTICAL ANALYSIS

High-Performance Liquid Chromatographic and Derivative Difference Spectrophotometric Methods for the Determination of Acetaminophen and Its Degradation Product in Aged Pharmaceutical Formulations

Ismail I. Hewala Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, University of Alexandria, Alexandria, 21521, Egypt.
Pages 561-582 | Received 01 Sep 1993, Accepted 27 Oct 1993, Published online: 22 Aug 2006

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Hamid Khan, Mushir Ali, Sayeed Ahmad, Niyaz Ahmad, Alka Ahuja, Sanjula Baboota & Javed Ali. (2012) VALIDATED UPLC/Q-TOF-MS METHOD FOR SIMULTANEOUS DETERMINATION OF ACECLOFENAC, PARACETAMOL, AND THEIR DEGRADATION PRODUCTS IN TABLETS. Journal of Liquid Chromatography & Related Technologies 35:1, pages 109-128.
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Articles from other publishers (26)

Ahmed Habib, Mokhtar M. Mabrouk, Marwa Fekry & Fotouh R. Mansour. (2023) Glycerol-Based Green RP-HPLC Method for Simultaneous Determination of Methionine and Paracetamol in Pharmaceutical Tablets. Chromatographia 86:11-12, pages 707-716.
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Ibrahim A. Naguib, Meral Majed, Maram Albogami, Maram Alshehri, Aseel Bukhari, Hadeel Alshabani, Izzeddin Alsalahat & Heba-Alla H. Abd-ElSalam. (2023) Greenness Assessment of HPLC Analytical Methods with Common Detectors for Assay of Paracetamol and Related Materials in Drug Products and Biological Fluids. Separations 10:5, pages 283.
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Parvateesam Yenda, Naresh Kumar Katari, Santhosh Kumar Ettaboina, Balasubramanian Satheesh, Siva Krishna Muchakayala & Rambabu Gundla. (2023) An effective and stability‐indicating method development and optimization utilizing the Box–Behnken design for the simultaneous determination of acetaminophen, caffeine, and aspirin in tablet formulation. Biomedical Chromatography 37:4.
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Cemil Caner Arıkan, Necla Kulabaş & İlkay Küçükgüzel. (2023) Synthesis and standardization of an impurity of acetaminophen, development and validation of liquid chromatographic method. Journal of Pharmaceutical and Biomedical Analysis 223, pages 115123.
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Sara Fateixa, Otílio Mulandeza, Helena I.S. Nogueira & Tito Trindade. (2022) Raman imaging studies on the stability of Paracetamol tablets under different storage conditions. Vibrational Spectroscopy, pages 103488.
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Thirupathi Dongala, Naresh Kumar Katari, Ashok Kumar Palakurthi & Sreekantha B. Jonnalagadda. (2019) Stability‐indicating HPLC method for simultaneous quantification of 14 impurities in excedrin tablet formulations and identification of new impurity by LC–MS in accelerated stability studies. Biomedical Chromatography 33:10.
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Karim Asadpour-Zeynali, S. Maryam Sajjadi & Fatemeh Taherzadeh. (2016) Second order advantage obtained by spectroelectrochemistry along with novel carbon nanotube modified mesh electrode: Application for determination of acetaminophen in Novafen samples. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 153, pages 674-680.
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O. Calinescu, I. A. Badea, L. Vladescu, V. Meltzer & E. Pincu. (2012) HPLC Separation of Acetaminophen and its Impurities Using A Mixed-mode Reversed-Phase/Cation Exchange Stationary Phase. Journal of Chromatographic Science 50:4, pages 335-342.
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Zemin Xu, Qu Yue, Zhenjing Zhuang & Dan Xiao. (2008) Flow injection amperometric determination of acetaminophen at a gold nanoparticle modified carbon paste electrode. Microchimica Acta 164:3-4, pages 387-393.
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Veronica Sima, Cecilia Cristea, Florina Lăpăduş, I.O. Marian, Ana Marian & R. Săndulescu. (2008) Electroanalytical properties of a novel biosensor modified with zirconium alcoxide porous gels for the detection of acetaminophen. Journal of Pharmaceutical and Biomedical Analysis 48:4, pages 1195-1200.
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Tamás Németh, Péter Jankovics, Júlia Németh-Palotás & Hilda Kőszegi-Szalai. (2008) Determination of paracetamol and its main impurity 4-aminophenol in analgesic preparations by micellar electrokinetic chromatography. Journal of Pharmaceutical and Biomedical Analysis 47:4-5, pages 746-749.
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Liqing Zhang & Liming Zhao. (2007) Simultaneous spectrophotometric determination of four components including acetaminophen by Taget Factor Analysis. Journal of Wuhan University of Technology-Mater. Sci. Ed. 22:3, pages 569-571.
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H. Filik & A. Tavman. (2007) A new cloud-point preconcentration approach for the spectrophotometric determination of p-aminophenol in the presence of paracetamol with 2-(2-Hydroxyphenyl)-1H-benzimidazole as a coupling reagent. Journal of Analytical Chemistry 62:6, pages 530-535.
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M. Espinosa Bosch, A.J. Ruiz Sánchez, F. Sánchez Rojas & C. Bosch Ojeda. (2006) Determination of paracetamol: Historical evolution. Journal of Pharmaceutical and Biomedical Analysis 42:3, pages 291-321.
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R. Nageswara Rao & A. Narasaraju. (2006) Rapid Separation and Determination of Process-Related Substances of Paracetamol Using Reversed-Phase HPLC with Photo Diode Array as a Detector. Analytical Sciences 22:2, pages 287-292.
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Zhang Liqing & Wu Xiaohua. (2005) Simultaneous spectrophotometric determination of three components including deoxyschizandrin by partial least squares regression. Journal of Wuhan University of Technology-Mater. Sci. Ed. 20:3, pages 119-121.
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Abdel-Aziz Y. El-Sayed & Najeb A. El-Salem. (2005) Recent Developments of Derivative Spectrophotometry and Their Analytical Applications. Analytical Sciences 21:6, pages 595-614.
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Tomás Pérez-Ruiz, Carmen Martínez-Lozano, Virginia Tomás & Raquel Galera. (2005) Migration behaviour and separation of acetaminophen and p-aminophenol in capillary zone electrophoresis: Analysis of drugs based on acetaminophen. Journal of Pharmaceutical and Biomedical Analysis 38:1, pages 87-93.
Crossref
Mannan Boopathi, Mi-Sook Won & Yoon-Bo Shim. (2004) A sensor for acetaminophen in a blood medium using a Cu(II)-conducting polymer complex modified electrode. Analytica Chimica Acta 512:2, pages 191-197.
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Lotfi Monser & Frida Darghouth. (2002) Simultaneous LC determination of paracetamol and related compounds in pharmaceutical formulations using a carbon-based column. Journal of Pharmaceutical and Biomedical Analysis 27:6, pages 851-860.
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Jalil Tavakoli Afshari & Tsan-Zon Liu. (2001) Rapid spectrophotometric method for the quantitation of acetaminophen in serum. Analytica Chimica Acta 443:1, pages 165-169.
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Yongnian Ni, Chao Liu & Serge Kokot. (2000) Simultaneous kinetic spectrophotometric determination of acetaminophen and phenobarbital by artificial neural networks and partial least squares. Analytica Chimica Acta 419:2, pages 185-196.
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Dan-Ke Xu, Hua Lin & Hong-Yuan Chen. (1997) Amperometric detection of enzymes in capillary zone electrophoresis based on dynamic modification with surfactants. Analytica Chimica Acta 349:1-3, pages 215-219.
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Jan F Van Bocxlaer, Karine M Clauwaert, Willy E Lambert & André P De Leenheer. (1997) Quantitative colorimetric determination of urinary p-aminophenol with an automated analyzer. Clinical Chemistry 43:4, pages 627-634.
Crossref
Yu-zhi Fang, Dajun Long & Jiannong Ye. (1997) Study of acetaminophen by parallel incident spectroelectrochemistry. Analytica Chimica Acta 342:1, pages 13-21.
Crossref
Wenfeng Peng, Tao Li, Huimei Li & Erkang Wang. (1994) Direct injection of urine and determination of acetaminophen by micellar liquid chromatography with a wall-jet cell/carbon fibre microelectrode. Analytica Chimica Acta 298:3, pages 415-421.
Crossref

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