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Analytical Letters Volume 29, 1996 - Issue 10
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PHARMACEUTICAL ANALYSIS

Spectrophotometric Methods for the Determination of Methotrexate in Pharmaceutical Formulations

Chilukuri S.P. Sastry Foods and Drugs Labs, Dept. of Organic Chemistry, Foods, Drugs and Water, Andhra University, Visakhapatnam, 530 003, India
&
Jana S.V.M. Lingeswara Rao Foods and Drugs Labs, Dept. of Organic Chemistry, Foods, Drugs and Water, Andhra University, Visakhapatnam, 530 003, India
Pages 1763-1778 | Received 17 Jan 1996, Accepted 15 Mar 1996, Published online: 18 Aug 2006

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Lenka Janíková-Bandžuchová & Renáta Šelešovská. (2016) Determination of Methotrexate at a Silver Solid Amalgam Electrode by Differential Pulse Voltammetry. Analytical Letters 49:1, pages 122-134.
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Nur Qadri Febrianti, Muhamad Gilang Ramadhan Tunggeng, Indianty Dwi Ramadhany, Rangga Meidianto Asri, Yulia Yusrini Djabir & Andi Dian Permana. (2024) Validation of UV–Vis spectrophotometric and colorimetric methods to quantify methotrexate in plasma and rat skin tissue: Application to in vitro release, ex vivo and in vivo studies from dissolving microarray patch loaded pH-sensitive nanoparticle. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 315, pages 124258.
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Nur Qadri Febrianti, Anugerah Yaumil Ramadhani Aziz, Muhamad Gilang Ramadhan Tunggeng, Indianty Dwi Ramadhany, Nur Syafika, Sumayya Binti Abd Azis, Yulia Yusrini Djabir, Rangga Meidianto Asri & Andi Dian Permana. (2024) Development of pH-Sensitive Nanoparticle Incorporated into Dissolving Microarray Patch for Selective Delivery of Methotrexate. AAPS PharmSciTech 25:4.
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Yanzhong Wang, Shuangshuang Li, Yuzhen Gao, Bo Du, Somayeh Vafaei, Manning Li, Han Wu, Xiangmin Tong & Yirui Chen. (2023) Synthesis of poly (L-cysteine)/g-C3N4 modified glassy carbon electrodes for electrochemical detection of methotrexate as a medicine for treatment of breast cancer in pharmaceutical fluid samples. Chemosphere 331, pages 138769.
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Fariba Garkani Nejad, Hadi Beitollahi & Iran Sheikhshoaie. (2023) Electrochemical sensing of methotrexate in the presence of folic acid using PAMAM dendrimer-functionalized multiwalled carbon nanotube-modified electrode. Analytical Methods 15:26, pages 3196-3205.
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Tingting Zhou, Ziwen Deng, Qing Wang, Hui Li, Shun Li, Xuanming Xu, Yusun Zhou, Shukai Sun, Chao Xuan, Qingwu Tian & Limin Lun. (2022) Magnetic Molecularly Imprinted Polymers for the Rapid and Selective Extraction and Detection of Methotrexatein Serum by HPLC-UV Analysis. Molecules 27:18, pages 6084.
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Somayeh Tajik, Hadi Beitollahi, Saeed Shahsavari & Fariba Garkani Nejad. (2022) Simultaneous and selective electrochemical sensing of methotrexate and folic acid in biological fluids and pharmaceutical samples using Fe3O4/ppy/Pd nanocomposite modified screen printed graphite electrode. Chemosphere 291, pages 132736.
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Mahdi Mollaei, Sayed Mehdi Ghoreishi & Asma Khoobi. (2020) Nano-molar level detection of calcium folinate and methotrexate using a cationic surfactant and multivariate optimization: A simple tool for simultaneous and sensitive analysis. Measurement 152, pages 107362.
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Bhuvanenthiran Mutharani, Palraj Ranganathan, Shen-Ming Chen & Pedaballi Sireesha. (2019) Ultrasound-induced radicals initiated the formation of inorganic–organic Pr2O3/polystyrene hybrid composite for electro-oxidative determination of chemotherapeutic drug methotrexate. Ultrasonics Sonochemistry 56, pages 410-421.
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Deqian Huang, Hai Wu, Yuyang Zhu, Huijuan Su, Hong Zhang, Liangquan Sheng, Zhaodi Liu, Huajie Xu & Chongfu Song. (2019) Sensitive Determination of Anticancer Drug Methotrexate Using Graphite Oxide-Nafion Modified Glassy Carbon Electrode. International Journal of Electrochemical Science 14:4, pages 3792-3804.
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Haifeng Zhou, Guoxia Ran, Jean-Francois Masson, Chan Wang, Yuan Zhao & Qijun Song. (2018) Novel tungsten phosphide embedded nitrogen-doped carbon nanotubes: A portable and renewable monitoring platform for anticancer drug in whole blood. Biosensors and Bioelectronics 105, pages 226-235.
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Jincheng Chen, Bo Fu, Tailin Liu, Zhihong Yan & Kang Li. (2017) A Graphene Oxide‐DNA Electrochemical Sensor Based on Glassy Carbon Electrode for Sensitive Determination of Methotrexate. Electroanalysis 30:2, pages 288-295.
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Ali A. Ensafi, Fatemeh Rezaloo & Behzad Rezaei. (2017) CoFe2O4/reduced graphene oxide/ionic liquid modified glassy carbon electrode, a selective and sensitive electrochemical sensor for determination of methotrexate. Journal of the Taiwan Institute of Chemical Engineers 78, pages 45-50.
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N. Swamy & K. Basavaiah. (2017) Spectrophotometric Determination of Rifampicin in Bulk Drug and Pharmaceutical Formulations Based on Redox and Complexation Reactions. Journal of Applied Spectroscopy 84:4, pages 694-703.
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Elham Asadian, Saeed Shahrokhian, Azam Iraji Zad & Fatemeh Ghorbani-Bidkorbeh. (2017) Glassy carbon electrode modified with 3D graphene–carbon nanotube network for sensitive electrochemical determination of methotrexate. Sensors and Actuators B: Chemical 239, pages 617-627.
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N. Swamy, K. N. Prashanth & K. Basavaiah. (2014) Redox-Reaction Based Spectrophotometric Assay of Isoniazid in Pharmaceuticals. ISRN Analytical Chemistry 2014, pages 1-11.
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Deborah Asbahr, Luiz Carlos S. Figueiredo-Filho, Fernando Campanhã Vicentini, Geiser Gabriel Oliveira, Orlando Fatibello-Filho & Craig E. Banks. (2013) Differential pulse adsorptive stripping voltammetric determination of nanomolar levels of methotrexate utilizing bismuth film modified electrodes. Sensors and Actuators B: Chemical 188, pages 334-339.
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Yanwei Wang, Hui Liu, Fei Wang & Yumei Gao. (2012) Electrochemical oxidation behavior of methotrexate at DNA/SWCNT/Nafion composite film-modified glassy carbon electrode. Journal of Solid State Electrochemistry 16:10, pages 3227-3235.
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Fei Wang, Yanwei Wang, Kui Lu, Xiaohan Wei & Baoxian Ye. (2012) Sensitive determination of methotrexate at nano-Au self-assembled monolayer modified electrode. Journal of Electroanalytical Chemistry 674, pages 83-89.
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Renáta Šelešovská, Lenka Bandžuchová & Tomáš Navrátil. (2010) Voltammetric Behavior of Methotrexate Using Mercury Meniscus Modified Silver Solid Amalgam Electrode. Electroanalysis 23:1, pages 177-187.
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Pavagada Ramesh, Kanakapura Basavaiah & Nagaraju Rajendraprasad. (2010) Sensitive and selective spectrophotometric assay of doxycycline hyclate in pharmaceuticals using Folin-Ciocalteu reagent. Acta Pharmaceutica 60:4, pages 445-454.
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D. Abd El-Hady, N. Abo El-Maali, R. Gotti, C. Bertucci, F. Mancini & V. Andrisano. (2005) Methotrexate determination in pharmaceuticals by enantioselective HPLC. Journal of Pharmaceutical and Biomedical Analysis 37:5, pages 919-925.
Crossref
Suzy M Sabry, M Abdel-Hady, M Elsayed, Osama T Fahmy & Hadir M Maher. (2003) Study of stability of methotrexate in acidic solution Spectrofluorimetric determination of methotrexate in pharmaceutical preparations through acid-catalyzed degradation reaction. Journal of Pharmaceutical and Biomedical Analysis 32:3, pages 409-423.
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A. Espinosa-Mansilla, I. Durán Merás, A. Zamora Madera, L. Pedano & C. Ferreyra. (2002) Kinetic fluorimetric determination of the antineoplastic methotrexate (MTX) in human serum. Journal of Pharmaceutical and Biomedical Analysis 29:5, pages 851-858.
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Chilukuri S. P. Sastry & Petla Y. Naidu. (1997) Spectrophotometric estimation of ketotifen fumarate in pharmaceutical formulations. Mikrochimica Acta 127:3-4, pages 219-223.
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Roger K. Gilpin & Lawrence A. Pachla. (1997) Pharmaceuticals and Related Drugs. Analytical Chemistry 69:12, pages 145-164.
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