Validation of a Method for Automated Nucleotide Sequence Analysis and Estimation of the Limits of Detection of Variant Sequences in a Heterogenic DNA Sample

D. J. Kobelt Grünenthal GmbH, Department of Molecular Pharmacology, Zieglerstraβe 6, D-52078, Aachen, Germany Phone: +49 241 569 2462 Fax: +49 241 569 2462

S. M. Hees Grünenthal GmbH, Department of Molecular Pharmacology, Zieglerstraβe 6, D-52078, Aachen, Germany Phone: +49 241 569 2462 Fax: +49 241 569 2462

R. D. Hildebrandt Grünenthal GmbH, Department of Molecular Pharmacology, Zieglerstraβe 6, D-52078, Aachen, Germany Phone: +49 241 569 2462 Fax: +49 241 569 2462

Stephan Wnendt Grünenthal GmbH, Department of Molecular Pharmacology, Zieglerstraβe 6, D-52078, Aachen, Germany Phone: +49 241 569 2462 Fax: +49 241 569 2462

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Validation of a Method for Automated Nucleotide Sequence Analysis and Estimation of the Limits of Detection of Variant Sequences in a Heterogenic DNA Sample

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Validation of a Method for Automated Nucleotide Sequence Analysis and Estimation of the Limits of Detection of Variant Sequences in a Heterogenic DNA Sample

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