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Analytical Letters Volume 31, 1998 - Issue 4
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Original Articles

Diastereomeric Analysis of Bioactive N-Phenylpyrazole-4-acylhydrazone Derivatives by High Resolution Gas Chromatography

A. S. Pereira Ladetec, Institute de Química, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Cidade Universitária, Centro de Tecnologia, Bloco A, Sala 607, Rio de Janeiro, RJ, Brazil
,
F. A. Violante LASSBio Faculdade de Farmácia Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
F. R. Aquino Neto Ladetec, Institute de Química, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Cidade Universitária, Centro de Tecnologia, Bloco A, Sala 607, Rio de Janeiro, RJ, Brazil
,
J. N. Cardoso Ladetec, Institute de Química, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Cidade Universitária, Centro de Tecnologia, Bloco A, Sala 607, Rio de Janeiro, RJ, Brazil
,
C. A.M. Fraga Ladetec, Institute de Química, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Cidade Universitária, Centro de Tecnologia, Bloco A, Sala 607, Rio de Janeiro, RJ, Brazil
&
E. J. Barreiro LASSBio Faculdade de Farmácia Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Pages 719-732 | Received 03 Nov 1997, Accepted 20 Nov 1997, Published online: 22 Aug 2006

Citations (9)

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Ana Paula C. Rodrigues, Luciana M.M. Costa, Bruna L.R. Santos, Rodolfo C. Maia, Ana L.P. Miranda, Eliezer J. Barreiro & Carlos A.M. Fraga. (2012) Novel furfurylidene N-acylhydrazones derived from natural safrole: discovery of LASSBio-1215, a new potent antiplatelet prototype. Journal of Enzyme Inhibition and Medicinal Chemistry 27:1, pages 101-109.
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Articles from other publishers (8)

Natalia de Morais Cordeiro, Rosana H.C.N. Freitas, Carlos Alberto Manssour Fraga & Patricia Dias Fernandes. (2020) New 2-amino-pyridinyl-N-acylhydrazones: Synthesis and identification of their mechanism of anti-inflammatory action. Biomedicine & Pharmacotherapy 123, pages 109739.
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Fanny Nascimento Costa, Tiago F. da Silva, Eduardo Miguez B. Silva, Regina C. R. Barroso, Delson Braz, Eliezer J. Barreiro, Lídia Moreira Lima, Francesco Punzo & Fabio Furlan Ferreira. (2015) Structural feature evolution – from fluids to the solid phase – and crystal morphology study of LASSBio 1601: a cyclohexyl-N-acylhydrazone derivative. RSC Advances 5:50, pages 39889-39898.
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Aline Guerra M. Fraga, Leandro Louback da Silva, Carlos Alberto Manssour Fraga & Eliezer J. Barreiro. (2011) CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. European Journal of Medicinal Chemistry 46:1, pages 349-355.
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Rodolfo C. Maia, Leandro L. Silva, Eduardo F. Mazzeu, Milla M. Fumian, Claudia M. de Rezende, Antonio C. Doriguetto, Rodrigo S. Corrêa, Ana Luisa P. Miranda, Eliezer J. Barreiro & Carlos Alberto Manssour Fraga. (2009) Synthesis and analgesic profile of conformationally constrained N-acylhydrazone analogues: Discovery of novel N-arylideneamino quinazolin-4(3H)-one compounds derived from natural safrole. Bioorganic & Medicinal Chemistry 17:18, pages 6517-6525.
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Anna C. Cunha, Juliana M. Figueiredo, Jorge L.M. Tributino, Ana L.P. Miranda, Helena C. Castro, Russolina B. Zingali, Carlos A.M. Fraga, Maria Cecı́lia B.V. de Souza, Vitor F. Ferreira & Eliezer J. Barreiro. (2003) Antiplatelet properties of novel N-substituted-phenyl-1,2,3-triazole-4-acylhydrazone derivatives. Bioorganic & Medicinal Chemistry 11:9, pages 2051-2059.
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Anna C Cunha, Jorge L.M Tributino, Ana L.P Miranda, Carlos A.M Fraga & Eliezer J Barreiro. (2002) Synthesis and pharmacological evaluation of novel antinociceptive N-substituted-phenylimidazolyl-4-acylhydrazone derivatives. Il Farmaco 57:12, pages 999-1007.
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Alberto dos Santos Pereira & Francisco Radler de Aquino Neto. (1999) High-temperature high-resolution gas chromatography: breaching the barrier to the analysis of polar and high molecular weight compounds. TrAC Trends in Analytical Chemistry 18:2, pages 126-136.
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Alberto S. Pereira, Angelo C. Pinto, Jari N. Cardoso, Francisco R. Aquino Neto, Paulo C. Vieira, João B. Fernandes, M. Fátima das G. F. da Silva & César C. Andrei. (1998) Analysis of Rotenoids by High Temperature High Resolution Gas Chromatography-Mass Spectrometry. Journal of High Resolution Chromatography 21:9, pages 513-518.
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