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Annals of Tropical Medicine & Parasitology Volume 31, 1937 - Issue 3
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Original Articles

Studies in Chemotherapy

XVI.—The Trypanocidal Action of Synthalin

E. M. Lourie
&
Warrington Yorke
Pages 435-445 | Received 05 Sep 1937, Published online: 24 Mar 2016

Citations (36)

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R. Wien. (1943) The Pharmacological Actions of Certain Aromatic Diamidines Possessing Trypanocidal Activity. Annals of Tropical Medicine & Parasitology 37:1, pages 1-18.
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Werner Schulemann. (1939) Problems and Progress in Chemotherapy. Annals of Tropical Medicine & Parasitology 33:2, pages 171-195.
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H. King, E. M. Lourie & Warrington Yorke. (1938) Studies in Chemotherapy. Annals of Tropical Medicine & Parasitology 32:2, pages 177-192.
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J. Devine. (1938) Studies in Chemotherapy. Annals of Tropical Medicine & Parasitology 32:2, pages 163-175.
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J. D. Fulton & S. Rickard Christophers. (1938) The Inhibitive Effect of Drugs Upon Oxygen Uptake by Trypanosomes (Trypanosoma Rhodesiense) and Malaria Parasites (Plasmodium Knowlesi). Annals of Tropical Medicine & Parasitology 32:1, pages 77-93.
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S. Rickard Christophers & J. D. Fulton. (1938) Observations on the Respiratory Metabolism of Malaria Parasites and Trypanosomes. Annals of Tropical Medicine & Parasitology 32:1, pages 43-75.
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Articles from other publishers (30)

Marzuq A. Ungogo & Harry P. de Koning. (2024) Drug resistance in animal trypanosomiases: Epidemiology, mechanisms and control strategies. International Journal for Parasitology: Drugs and Drug Resistance 25, pages 100533.
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Harry P. De Koning. (2020) The Drugs of Sleeping Sickness: Their Mechanisms of Action and Resistance, and a Brief History. Tropical Medicine and Infectious Disease 5:1, pages 14.
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Katherine T. Andrews, Gillian Fisher & Tina S. Skinner-Adams. (2014) Drug repurposing and human parasitic protozoan diseases. International Journal for Parasitology: Drugs and Drug Resistance 4:2, pages 95-111.
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Jose A. Garcia-Salcedo, Jane C. Munday, Juan D. Unciti-Broceta & Harry P. de Koning. 2014. Trypanosomes and Trypanosomiasis. Trypanosomes and Trypanosomiasis 217 238 .
Nicola Baker, Harry P. de Koning, Pascal M?ser & David Horn. (2013) Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story. Trends in Parasitology 29:3, pages 110-118.
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Eileen I Short. (1953) CHEMOTHERAPY: THE LABORATORY ASSESSMENT OF NEW DRUGS. Journal of Pharmacy and Pharmacology 5:1, pages 217-238.
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Maxime Mourer, Hugues Massimba Dibama, St?phane Fontanay, Marion Grare, Rapha?l E. Duval, Chantal Finance & Jean-Bernard Regnouf-de-Vains. (2009) p-Guanidinoethyl calixarene and parent phenol derivatives exhibiting antibacterial activities. Synthesis and biological evaluation. Bioorganic & Medicinal Chemistry 17:15, pages 5496-5509.
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Maxime Mourer, Raphaël E. Duval, Chantal Finance & Jean-Bernard Regnouf-de-Vains. (2006) Functional organisation and gain of activity: The case of the antibacterial tetra-para-guanidinoethyl-calix[4]arene. Bioorganic & Medicinal Chemistry Letters 16:11, pages 2960-2963.
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Gour Hari Jana, Sanjay Jain, Sudershan K. Arora & Neelima Sinha. (2005) Synthesis of some diguanidino 1-methyl-2,5-diaryl-1H-pyrroles as antifungal agents. Bioorganic & Medicinal Chemistry Letters 15:15, pages 3592-3595.
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Satyavan Sharma & Nitya Anand. 1997. Approaches to Design and Synthesis of Antiparasitic Drugs. Approaches to Design and Synthesis of Antiparasitic Drugs 455 461 .
Joseph M. Miller. (1989) Diamidine Use in Treatment of Pneumocystis carinii. Infection Control and Hospital Epidemiology 10:8, pages 344-344.
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James Williamson. (1979) Effects of trypanocides on the fine structure of target organisms. Pharmacology & Therapeutics 7:3, pages 445-512.
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L. G. Goodwin & Ellen D. Tierney. (2009) Trypanocidal activity of blood and tissue fluid from normal and infected rabbits treated with curative drugs. Parasitology 74:1, pages 33-45.
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. 1971. All Heal. All Heal 113 133 .
W.B. HUGO. 1971. Inhibition and Destruction of the Microbial Cell. Inhibition and Destruction of the Microbial Cell 121 136 .
Richard S. Bornstein & J. W. Yarbro. (2006) An evaluation of the mechanism of action of pentamidine isethionate. Journal of Surgical Oncology 2:4, pages 393-398.
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A. R. Patel, S. T. Reid, M. H. Bickel, E. Renk, W. G. Stoll & A. KreutzbergerAlfred Kreutzberger. 1968. Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques. Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques 356 445 .
FRANK HAWKING. 1963. Experimental Chemotherapy. Experimental Chemotherapy 129 256 .
Bruce A. Newton. 1963. Metabolic Inhibitors. Metabolic Inhibitors 285 310 .
J. WILLIAMSON & I. M. ROLLO. (2012) DRUG RESISTANCE IN TRYPANOSOMES; CROSS‐RESISTANCE ANALYSES. British Journal of Pharmacology and Chemotherapy 14:4, pages 423-430.
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C. H. Browning. (2010) THE CHEMOTHERAPY OF TRYPANOSOME INFECTIONS. Annals of the New York Academy of Sciences 59:2, pages 198-213.
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Martin Kuna & M. J. Kopac. (2006) THE SYNTHESIS AND PHYSICAL‐CHEMICAL PROPERTIES OF NEW AROMATIC AMIDINES. Annals of the New York Academy of Sciences 58:3, pages 263-292.
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H. P. KaufmannH. P. Kaufmann. 1953. Arzneimittel-Synthese. Arzneimittel-Synthese 518 742 .
THEODOR VON BRAND. 1951. Biochemistry and Physiology of Protozoa. Biochemistry and Physiology of Protozoa 177 234 .
Felix Bergmann, Irwin B. Wilson & David Nachmansohn. (1950) The inhibitory effect of stilbamidine, curare and related compounds and its relationship to the active groups of acetylcholine esterase. Action of stilbamidine upon nerve impulse conduction. Biochimica et Biophysica Acta 6, pages 217-224.
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P. B. MARSHALL. (2012) THE GLUCOSE METABOLISM OF TRYPANOSOMA EVANSI AND THE ACTION OF TRYPANOCIDES . British Journal of Pharmacology and Chemotherapy 3:1, pages 8-14.
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. (1940) BIOLOGICAL APPROACH TO CHEMOTHERAPY. The Lancet 235:6078, pages 369-370.
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. (1940) SEXUAL INTERGRADES. The Lancet 235:6078, pages 369.
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Paul Browning. (2005) The chemotherapeutic action of synthalin in experimental infections with T. brucei and T. congolense . The Journal of Pathology and Bacteriology 46:2, pages 323-329.
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H. King, E.M. Lourie & Warrington Yorke. (1937) NEW TRYPANOCIDAL SUBSTANCES. The Lancet 230:5963, pages 1360-1363.
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