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Original Articles

Studies on Synthetic Antimalarial Drugs

XIII.—Results of a Preliminary Investigation of the Therapeutic Action of 4888 (Paludrine) on Acute Attacks of Benign Tertian Malaria

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Pages 225-231 | Received 16 Nov 1945, Published online: 22 Mar 2016

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A. E. T. Yeo, M. D. Edstein, G. D. Shanks & K. H. Rieckmann. (1994) A statistical analysis of the antimalarial activity of proguanil and cycloguanil in human volunteers. Annals of Tropical Medicine & Parasitology 88:6, pages 587-594.
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R. E. Howells. (1987) The antimalarial action of chloroquine and mechanisms of resistance. Annals of Tropical Medicine & Parasitology 81:5, pages 629-637.
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W. M. Watkins, D. G. Sixsmith & J. D. Chulay. (1984) The activity of proguanil and its metabolites, cycloguanil and p-chlorophenylbiguanide, against Plasmodium falciparum in vitro. Annals of Tropical Medicine & Parasitology 78:3, pages 273-278.
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A. Halawani, I. Baz & F. Morcos. (1948) Field Trials with New Antimalarial Drugs in Egypt. Annals of Tropical Medicine & Parasitology 42:3-4, pages 304-311.
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A. Spinks. (1948) Studies on Synthetic Antimalarial Drugs. Annals of Tropical Medicine & Parasitology 42:2, pages 190-197.
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W. H. Horner Andrews, D. Gall & B. G. Maegraith. (1947) Studies on Synthetic Antimalarial Drugs. Annals of Tropical Medicine & Parasitology 41:3-4, pages 375-379.
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A. Spinks. (1947) Studies on Synthetic Antimalarial Drugs. Annals of Tropical Medicine & Parasitology 41:1, pages 30-38.
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B. G. Maegraith, Mary M. Tottey, A. R. D. Adams, W. H. Horner Andrews & J. D. King. (1946) The Absorption and Excretion of Paludrine in the Human Subject. Annals of Tropical Medicine & Parasitology 40:3-4, pages 493-506.
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B. G. Maegraith, A. R. D. Adams, J. D. King, R. H. Townshend, T. H. Davey & R. E. Havard. (1945) Studies on Synthetic Antimalarial Drugs. Annals of Tropical Medicine & Parasitology 39:3-4, pages 232-236.
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Articles from other publishers (12)

Mark William Irvine. 2020. Antimalarial Agents. Antimalarial Agents 133 185 .
D.H Molyneux. (1998) The Liverpool School of Tropical Medicine: 100 Years of Parasitological Achievement. Parasitology Today 14:11, pages 440-443.
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David A. Fidock & Thomas E. Wellems. (1997) Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil. Proceedings of the National Academy of Sciences 94:20, pages 10931-10936.
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. 1972. Antimalarial Agents - Chemistry and Pharmacology. Antimalarial Agents - Chemistry and Pharmacology 233 250 .
F. Kurzer & E. D. Pitchfork. 1968. Biguanides. Biguanides 375 472 .
J. HILL. 1963. Experimental Chemotherapy. Experimental Chemotherapy 513 601 .
K.A. Schellenberg & G.R. Coatney. (1961) The influence of antimalarial drugs on nucleic acid synthesis in Plasmodium gallinaceum and Plasmodium berghei. Biochemical Pharmacology 6:3, pages 143-152.
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Quentin M. Geiman. (1948) Malaria. New England Journal of Medicine 239:2, pages 58-64.
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J.F. Monk. (1948) Results of an investigation of the therapeutic action of paludrine and pamaquin on acute attacks of benign tertian malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene 41:5, pages 657-662.
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RUTH BUTLER, D. G. DAVEY & A. SPINKS. (2012) A PRELIMINARY REPORT OF THE TOXICITY AND THE ASSOCIATED BLOOD CONCENTRATIONS OF PALUDRINE* IN LABORATORY ANIMALS. British Journal of Pharmacology and Chemotherapy 2:3, pages 181-188.
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ANN BISHOP & BETTY BIRKETT. (1947) Acquired Resistance to Paludrine in Plasmodium Gallinaceum. Nature 159:4052, pages 884-885.
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EarlJ. King, I.D.P. Wootton & Margaret Gilchrist. (1946) ESTIMATION OF PALUDRINE IN BLOOD. The Lancet 247:6407, pages 886-887.
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