Advanced search
Publication Cover
Annals of Tropical Medicine & Parasitology Volume 40, 1946 - Issue 1
Journal homepage
5
Views
20
CrossRef citations to date
0
Altmetric
Original Articles

Studies on Synthetic Antimalarial Drugs

XV.—Hydrolytic Determination of Paludrine

A. Spinks From the Research Laboratories, Imperial Chemical Industries Limited, Hexagon House, Manchester
&
Mary M. Tottey From the Research Laboratories, Imperial Chemical Industries Limited, Hexagon House, Manchester
Pages 101-112 | Received 01 Feb 1946, Published online: 22 Mar 2016

Citations (20)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

A. Spinks. (1948) Studies on Synthetic Antimalarial Drugs. Annals of Tropical Medicine & Parasitology 42:2, pages 190-197.
Read now
B. G. Maegraith, Mary M. Tottey, A. R. D. Adams, W. H. Horner Andrews & J. D. King. (1946) The Absorption and Excretion of Paludrine in the Human Subject. Annals of Tropical Medicine & Parasitology 40:3-4, pages 493-506.
Read now

Articles from other publishers (18)

H E Stagg. (1949) The Determination of Proguanil. Journal of Pharmacy and Pharmacology 1:1, pages 391-394.
Crossref
R.B. Taylor, R. Behrens, R.R. Moody & J. Wangboonskul. (1990) Assay method for the simultaneous determination of proguanil, chloroquine and their major metabolites in biological fluids. Journal of Chromatography B: Biomedical Sciences and Applications 527, pages 490-497.
Crossref
SA Ward, WM Watkins, E Mberu, JE Saunders, DK Koech, HM Gilles, RE Howells & AM Breckenridge. (2012) Inter‐subject variability in the metabolism of proguanil to the active metabolite cycloguanil in man.. British Journal of Clinical Pharmacology 27:6, pages 781-787.
Crossref
W.M. Watkins, M. Percy, J.M. Crampton, S. Ward, D. Koech & R.E. Howells. (1988) The changing response of Plasmodium falciparum to antimalarial drugs in East Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene 82:1, pages 21-26.
Crossref
Y Wattanagoon, RB Taylor, RR Moody, NA Ochekpe, S Looareesuwan & NJ White. (2012) Single dose pharmacokinetics of proguanil and its metabolites in healthy subjects.. British Journal of Clinical Pharmacology 24:6, pages 775-780.
Crossref
R.B. Taylor, R.R. Moody & N.A. Ochekpe. (1987) Determination of proguanil and its metabolites cycloguanil and 4-chlorophenylbiguanide in plasma, whole blood and urine by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 416, pages 394-399.
Crossref
M.D. Edstein. (1986) Simultaneous measurement of proguanil and cycloguanil in human plasma by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 380, pages 184-189.
Crossref
L H Schmidt & R N Rossan. (1984) Activities of respository preparations of cycloguanil pamoate and 4,4'-diacetyldiaminodiphenylsulfone, alone and in combination, against infections with Plasmodium cynomolgi in rhesus monkeys. Antimicrobial Agents and Chemotherapy 26:5, pages 611-642.
Crossref
. 1972. Antimalarial Agents - Chemistry and Pharmacology. Antimalarial Agents - Chemistry and Pharmacology 233 250 .
F. Kurzer & E. D. Pitchfork. 1968. Biguanides. Biguanides 375 472 .
J. HILL. 1963. Experimental Chemotherapy. Experimental Chemotherapy 513 601 .
A. F. CROWTHER & A. A. LEVI. (2012) PROGUANIL—THE ISOLATION OF A METABOLITE WITH HIGH ANTIMALARIAL ACTIVITY. British Journal of Pharmacology and Chemotherapy 8:1, pages 93-97.
Crossref
J. FRANCIS & A. SPINKS. (2012) ANTIBACTERIAL ACTION AND METABOLISM OF FIVE SULPHONES. British Journal of Pharmacology and Chemotherapy 5:4, pages 565-583.
Crossref
Robert C. Shultz. (1949) Hydrogenolysis as a Method for Determining Chlorguanide (paludrine). Journal of the American Pharmaceutical Association (Scientific ed.) 38:2, pages 84-85.
Crossref
FRANK HAWKING & WALTER L. M. PERRY. (2012) ACTIVATION OF PALUDRINE. British Journal of Pharmacology and Chemotherapy 3:4, pages 320-325.
Crossref
RUTH BUTLER, D. G. DAVEY & A. SPINKS. (2012) A PRELIMINARY REPORT OF THE TOXICITY AND THE ASSOCIATED BLOOD CONCENTRATIONS OF PALUDRINE* IN LABORATORY ANIMALS. British Journal of Pharmacology and Chemotherapy 2:3, pages 181-188.
Crossref
F. L. ROSE & A. SPINKS. (2012) THE ABSORPTION OF SOME SULPHAGUANIDINE DERIVATIVES IN MICE. British Journal of Pharmacology and Chemotherapy 2:2, pages 65-78.
Crossref
A. Spinks. (2016) Studies on Synthetic Antimalarial Drugs. Annals of Tropical Medicine & Parasitology 41:1, pages 30-38.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.