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Annals of Tropical Medicine & Parasitology Volume 79, 1985 - Issue 6
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Original Articles

Malaria control by chlorproguanil

I. Clinical effects and susceptibility of Plasmodium falciparum in vivo after seven years of monthly chlorproguanil administration to children in a Liberian village

A. BjörkmanThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
,
J. BrohultThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
,
M. WillcoxThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
,
P. O. PehrsonThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
,
L. RomboThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
,
P. HedmanThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
,
G. HetlandThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
,
E. KollieThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
,
A. P. HansonThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
&
E. BengtssonThe Tekepa Clinical Research and Training Unit of the Liberian Institute for Biomedical Research, Liberia and Department of Infectious Diseases, Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
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Pages 597-601 | Received 06 Jul 1984, Published online: 15 Nov 2016

Citations (13)

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Allan Schapira. (1990) The Resistance of Falciparum Malaria in Africa to 4-Aminoquinolines and Antifolates. Scandinavian Journal of Infectious Diseases 22:sup75, pages 1-64.
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E. Petersen, B. Hogh, A. P. Hanson, A. Bjorkman & H. Flacks. (1990) In vitro and in vivo susceptibility of Plasmodium falciparum isolates from Liberia to pyrimethamine, cycloguanil and chlorcycloguanil. Annals of Tropical Medicine & Parasitology 84:6, pages 563-571.
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Articles from other publishers (11)

Limei Guo & Weike Zhang. (2022) Knowledge mapping of population health: A bibliometric analysis. Heliyon 8:12, pages e12181.
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Irina T. Jovel, Anders Björkman, Cally Roper, Andreas Mårtensson & Johan Ursing. (2017) Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976–78. Malaria Journal 16:1.
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Martin M Meremikwu, Sarah Donegan, David Sinclair, Ekpereonne Esu & Chioma Oringanje. (2012) Intermittent preventive treatment for malaria in children living in areas with seasonal transmission. Cochrane Database of Systematic Reviews.
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Martin M Meremikwu, Sarah Donegan & Ekpereonne Esu. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
MM Meremikwu, AAA Omari & P Garner. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
G. A. T. Targett. (2009) Malaria: drug use and the immune response. Parasitology 105:S1, pages S61-S70.
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S.J. Allen, L.N. Otoo, G.A. Cooke, A. O'Donnell & B.M. Greenwood. (1990) Sensitivity of Plasmodium falciparum to chlorproguanil in Gambian children after five years of continuous chemoprophylaxis. Transactions of the Royal Society of Tropical Medicine and Hygiene 84:2, pages 218.
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B.M. Greenwood, A.M. Greenwood, A.W. Smith, A. Menon, A.K. Bradley, R.W. Snow, F. Sisay, S. Bennett, W.M. Watkins & A.B.H. N'Jie. (1989) A comparative study of Lapudrine® (chlorproguanil) and Maloprim® (pyrimethamine and dapsone) as chemoprophylactics against malaria in Gambian children. Transactions of the Royal Society of Tropical Medicine and Hygiene 83:2, pages 182-188.
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R. B. Taylor, R. R. Moody, N. A. Ochekepe & B. Law. (1987) Determination of chlorproguanil and metabolites in biological fluids. Chromatographia 24:1, pages 560-564.
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M.H. Coosemans, M. Barutwanayo, E. Onori, C. Otoul, B. Gryseels & M. Wéry. (1987) Double-blind study to assess the efficacy of chlorproguanil given alone or in combination with chloroquine for malaria chemoprophylaxis in an area with Plasmodium falciparum resistance to chloroquine, pyrimethamine and cycloguanil. Transactions of the Royal Society of Tropical Medicine and Hygiene 81:1, pages 151-156.
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M.D. Edstein & J.R. Veenendaal. (1987) Chlorproguanil and chlorcycloguanil concentrations in human plasma and urine after Lapudrine® administration. Transactions of the Royal Society of Tropical Medicine and Hygiene 81:1, pages 136-139.
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