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Annals of Tropical Medicine & Parasitology Volume 83, 1989 - Issue 5
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Original Articles

Antileishmanial effects of clofazimine and other antimycobacterial agents

A. T. EvansDepartment of Medical Protozoology, London School of Hygiene and Tropical Medicine, Keppel Street, LondonWC1E 7HT, U.K.
,
S. L. CroftDepartment of Medical Protozoology, London School of Hygiene and Tropical Medicine, Keppel Street, LondonWC1E 7HT, U.K.
,
W. PetersDepartment of Medical Protozoology, London School of Hygiene and Tropical Medicine, Keppel Street, LondonWC1E 7HT, U.K.
&
R. A. NealDepartment of Medical Protozoology, London School of Hygiene and Tropical Medicine, Keppel Street, LondonWC1E 7HT, U.K.
Pages 447-454 | Received 18 Feb 1988, Published online: 15 Nov 2016

Citations (15)

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Robert O'connor, J. F. O'sullivan & Richard O'kennedy. (1995) The Pharmacology, Metabolism, and Chemistry of Clofazimine. Drug Metabolism Reviews 27:4, pages 591-614.
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Articles from other publishers (14)

Nooshin Biglari-Moghadam, Hossein Najafzadehvarzi, Tahmineh Gorgani-Firouzjaee & Maryam Ghasemi-Kasman. (2023) Efficacy of clofazimine against acute and chronic Toxoplasma gondii infection in mice. Microbial Pathogenesis 181, pages 106206.
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Ivan Bassanini, Silvia Parapini, Nicoletta Basilico & Anna Sparatore. (2019) Novel Hydrophilic Riminophenazines as Potent Antiprotozoal Agents. ChemMedChem 14:22, pages 1940-1949.
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SILVIA R. B. ULIANA, CRISTIANA T. TRINCONI & ADRIANO C. COELHO. (2017) Chemotherapy of leishmaniasis: present challenges. Parasitology 145:4, pages 464-480.
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Bumduuren Tuvshintulga, Mahmoud AbouLaila, Batdorj Davaasuren, Aki Ishiyama, Thillaiampalam Sivakumar, Naoaki Yokoyama, Masato Iwatsuki, Kazuhiko Otoguro, Satoshi Ōmura & Ikuo Igarashi. (2016) Clofazimine Inhibits the Growth of Babesia and Theileria Parasites In Vitro and In Vivo . Antimicrobial Agents and Chemotherapy 60:5, pages 2739-2746.
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Marcel Kaiser, Pascal Mäser, Leela Pavan Tadoori, Jean-Robert Ioset & Reto Brun. (2015) Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning. PLOS ONE 10:8, pages e0135556.
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Anna Barteselli, Manolo Casagrande, Nicoletta Basilico, Silvia Parapini, Chiara M. Rusconi, Michele Tonelli, Vito Boido, Donatella Taramelli, Fabio Sparatore & Anna Sparatore. (2015) Clofazimine analogs with antileishmanial and antiplasmodial activity. Bioorganic & Medicinal Chemistry 23:1, pages 55-65.
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Michele Tonelli, Federica Novelli, Bruno Tasso, Anna Sparatore, Vito Boido, Fabio Sparatore, Sara Cannas, Paola Molicotti, Stefania Zanetti, Silvia Parapini & Roberta Loddo. (2014) Antitubercular activity of quinolizidinyl/pyrrolizidinylalkyliminophenazines. Bioorganic & Medicinal Chemistry 22:24, pages 6837-6845.
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M. N. S. Saudi, M. M. A. El-Semary, R. Y. Elbayaa, M. I. Jaeda, M. M. Eissa, E. I. Amer & N. M. Baddour. (2010) Synthesis and biological evaluation of a novel class as antileishmanial agent. Medicinal Chemistry Research 21:2, pages 257-267.
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Mohammad Reza Namazi, Ladan Dastgheib, Jaber Mazandarani & Farideh Jowkar. (2010) Clofazimine, an antimycobacterial with potent in vitro and in vivo leishmanicidal activity, is ineffective against cutaneous Leishmania major infection in humans. Journal of the American Academy of Dermatology 62:5, pages 890-892.
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Marcelo Genestra, Aurea Echevarria, Léa Cysne-Finkelstein, Luciana Vignólio-Alves & Leonor L Leon. (2003) Effect of amidine derivatives on nitric oxide production by Leishmania amazonensis promastigotes and axenic amastigotes. Nitric Oxide 8:1, pages 1-6.
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Jack L Arbiser & Samuel L Moschella. (1995) Clofazimine: A review of its medical uses and mechanisms of action. Journal of the American Academy of Dermatology 32:2, pages 241-247.
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A.Tudor Evans & Simon L. Croft. (1994) Antileishmanial actions of tricyclic neuroleptics appear to lack structural specificity. Biochemical Pharmacology 48:3, pages 613-616.
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A. Bourgeade & Y. Nosny. (1994) Leishmaniose viscérale : actualités thérapeutiques. Médecine et Maladies Infectieuses 24:5, pages 614-621.
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M Hooper. (1991) Use of thalidomide in leprosy.. BMJ 303:6814, pages 1404-1405.
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