6
Views
46
CrossRef citations to date
0
Altmetric
Original Articles

Blood-brain barrier damage in experimental African trypanosomiasis

, , &
Pages 607-616 | Received 01 Jun 1994, Accepted 02 Aug 1994, Published online: 15 Nov 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Dennis J Grab & Peter GE Kennedy. (2008) Traversal of human and animal trypanosomes across the blood-brain barrier. Journal of Neurovirology 14:5, pages 344-351.
Read now

Articles from other publishers (45)

Juan F. Quintana, Matthew C. Sinton, Praveena Chandrasegaran, Lalit Kumar Dubey, John Ogunsola, Moumen Al Samman, Michael Haley, Gail McConnell, Nono-Raymond Kuispond Swar, Dieudonné Mumba Ngoyi, David Bending, Luis de Lecea, Annette MacLeod & Neil A. Mabbott. (2023) The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection. PLOS Biology 21:11, pages e3002389.
Crossref
Samantha Paterson, Antoine Vallatos, Jean Rodgers & William M. Holmes. (2023) Application of diffusion weighted multiple boli ASL to a murine model of human African trypanosomiasis. Scientific Reports 13:1.
Crossref
Neloy Kumar Chakroborty, Sabyasachi Baksi & Arijit Bhattacharya. 2023. Pathobiology of Parasitic Protozoa: Dynamics and Dimensions. Pathobiology of Parasitic Protozoa: Dynamics and Dimensions 61 94 .
Davinson C. Anyogu, Shodeinde V. O. Shoyinka & John I. Ihedioha. (2022) Brain and pituitary-adrenal lesions of Trypanosoma brucei brucei and Trypanosoma congolense infections in the West African Dwarf rams: Is trypanotolerance overrated? . Veterinary Pathology 59:5, pages 773-781.
Crossref
Paul Montague, Barbara Bradley, Jean Rodgers & Peter G. E. Kennedy. (2021) Microarray profiling predicts early neurological and immune phenotypic traits in advance of CNS disease during disease progression in Trypanosoma. b. brucei infected CD1 mouse brains. PLOS Neglected Tropical Diseases 15:11, pages e0009892.
Crossref
Jean RodgersIsrael SteinerPeter G. E Kennedy. (2019) Generation of neuroinflammation in human African trypanosomiasis. Neurology Neuroimmunology & Neuroinflammation 6:6.
Crossref
Paula MacGregor, Andrea L. Gonzalez-Munoz, Fatoumatta Jobe, Martin C. Taylor, Steven Rust, Alan M. Sandercock, Olivia J. S. Macleod, Katrien Van Bocxlaer, Amanda F. Francisco, Francois D’Hooge, Arnaud Tiberghien, Conor S. Barry, Philip Howard, Matthew K. Higgins, Tristan J. Vaughan, Ralph Minter & Mark Carrington. (2019) A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis. PLOS Neglected Tropical Diseases 13:5, pages e0007373.
Crossref
Peter G. E. Kennedy & Jean Rodgers. (2019) Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis. Frontiers in Immunology 10.
Crossref
Jean Rodgers, Barbara Bradley & Peter G.E. Kennedy. (2017) Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis. Methods 127, pages 79-87.
Crossref
Jonathan A. Coles, Elmarie Myburgh, Ryan Ritchie, Alana Hamilton, Jean Rodgers, Jeremy C. Mottram, Michael P. Barrett & James M. Brewer. (2015) Intravital Imaging of a Massive Lymphocyte Response in the Cortical Dura of Mice after Peripheral Infection by Trypanosomes. PLOS Neglected Tropical Diseases 9:4, pages e0003714.
Crossref
Muthusamy Ranjithkumar, Buddhi Chandrasekaran Saravanan, Suresh Chandra Yadav, Rajender Kumar, Rajendra Singh & Sahadeb Dey. (2013) Neurological trypanosomiasis in quinapyramine sulfate-treated horses—a breach of the blood–brain barrier?. Tropical Animal Health and Production 46:2, pages 371-377.
Crossref
Gayathri N. Sekhar, Christopher P. Watson, Mehmet Fidanboylu, Lisa Sanderson & Sarah A. Thomas. 2014. Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders. Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders 245 275 .
Jann Hau & Steven SchapiroIdle Farah, Maina Ngotho, John Kagira, Thomas Kariuki, Maamun Jeneby, Naomi Maina, Michael Gicheru, Hastings Ozwara & Jann Hau. 2013. Handbook of Laboratory Animal Science, Volume III, Third Edition. Handbook of Laboratory Animal Science, Volume III, Third Edition 43 106 .
L. MacLean, E. Myburgh, J. Rodgers & H. P. Price. (2013) Imaging A frican trypanosomes . Parasite Immunology 35:9-10, pages 283-294.
Crossref
Krister Kristensson, Willias Masocha & Marina Bentivoglio. 2013. Neuroparasitology and Tropical Neurology. Neuroparasitology and Tropical Neurology 11 22 .
G Caljon, V Caveliers, T Lahoutte, B Stijlemans, GH Ghassabeh, J Van Den Abbeele, I Smolders, P De Baetselier, Y Michotte, S Muyldermans, S Magez & R Clinckers. (2012) Using microdialysis to analyse the passage of monovalent nanobodies through the blood–brain barrier. British Journal of Pharmacology 165:7, pages 2341-2353.
Crossref
Nathalie Geurts, Ghislain Opdenakker & Philippe E. Van den Steen. (2012) Matrix metalloproteinases as therapeutic targets in protozoan parasitic infections. Pharmacology & Therapeutics 133:3, pages 257-279.
Crossref
S. Bisser & B. Courtioux. (2012) La maladie du sommeil, fin d?une ?pid?mie??. Revue Neurologique 168:3, pages 230-238.
Crossref
Barbara Bradley, Jean Rodgers, Barrie Condon, Christopher McCabe, Peter G. E. Kennedy & George Gettinby. (2011) Magnetic Resonance Imaging to Assess Blood–Brain Barrier Damage in Murine Trypanosomiasis. The American Journal of Tropical Medicine and Hygiene 84:2, pages 344-350.
Crossref
Conrad Johanson, Edward Stopa, Paul McMillan, Daniel Roth, Juergen Funk & Georg Krinke. (2010) The Distributional Nexus of Choroid Plexus to Cerebrospinal Fluid, Ependyma and Brain. Toxicologic Pathology 39:1, pages 186-212.
Crossref
JEAN RODGERS. (2009) Trypanosomiasis and the brain. Parasitology 137:14, pages 1995-2006.
Crossref
Hany M. Elsheikha & Naveed Ahmed Khan. (2010) Protozoa traversal of the blood–brain barrier to invade the central nervous system. FEMS Microbiology Reviews 34:4, pages 532-553.
Crossref
Debjani Biswas, Amalesh Choudhury & Kamales Kumar Misra. (2010) Histopathology of Trypanosoma (Trypanozoon) evansi infection in Bandicoot rat. II. Brain and choroid plexus. Proceedings of the Zoological Society 63:1, pages 27-37.
Crossref
Jean Rodgers. (2009) Human African trypanosomiasis, chemotherapy and CNS disease. Journal of Neuroimmunology 211:1-2, pages 16-22.
Crossref
Lisa Sanderson, Murat Dogruel, Jean Rodgers, Barbara Bradley & Sarah Ann Thomas. (2008) The blood–brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain 1 . Journal of Neurochemistry 107:4, pages 1136-1146.
Crossref
David EllisonSebastian Lucas, Jeanne Bell & Leila Chimelli. 2008. Greenfield's Neuropathology Eighth Edition. 2 Volume Set and DVD. Greenfield's Neuropathology Eighth Edition. 2 Volume Set and DVD 1447 1511 .
S. Semballa, M.C. Okomo-Assoumou, P. Holzmuller, P. B?scher, S. Magez, J.L. Lemesre, S. Daulouede, P. Courtois, M. Geffard & P. Vincendeau. (2007) Identification of a tryptophan-like epitope borne by the variable surface glycoprotein (VSG) of African trypanosomes. Experimental Parasitology 115:2, pages 173-180.
Crossref
S. Bisser, O.N. Ouwe-Missi-Oukem-Boyer, F.S. Toure, Z. Taoufiq, B. Bouteille, A. Buguet & D. Mazier. (2006) Harbouring in the brain: A focus on immune evasion mechanisms and their deleterious effects in malaria and human African trypanosomiasis. International Journal for Parasitology 36:5, pages 529-540.
Crossref
Mahalia S. Desruisseaux, Louis M. Weiss, Herbert B. Tanowitz, Adam Mott & Danny A. Milner. 2006. Blood‐Brain Barriers. Blood‐Brain Barriers 671 700 .
Murielle Girard, Stéphanie Giraud, Bertrand Courtioux, Marie-Odile Jauberteau-Marchan & Bernard Bouteille. (2005) Endothelial cell activation in the presence of African trypanosomes. Molecular and Biochemical Parasitology 139:1, pages 41-49.
Crossref
Idle Farah, Maina Ngotho, Thomas Kariuki, Maamun Jeneby, Lawrence Irura, Naomi Maina, John Kagira, Michael Gicheru & Jann Hau. 2004. Handbook of Laboratory Animal Science, Second Edition. Handbook of Laboratory Animal Science, Second Edition 169 223 .
R. Bryan Rock, Genya Gekker, Shuxian Hu, Wen S. Sheng, Maxim Cheeran, James R. Lokensgard & Phillip K. Peterson. (2004) Role of Microglia in Central Nervous System Infections. Clinical Microbiology Reviews 17:4, pages 942-964.
Crossref
A. Darsaud, L. Bourdon, C. Chevrier, M. Keita, B. Bouteille, A. Queyroy, F. Canini, R. Cespuglio, M. Dumas & A. Buguet. (2016) Clinical Follow-Up in the Rat Experimental Model of African-Trypanosomiasis. Experimental Biology and Medicine 228:11, pages 1355-1362.
Crossref
Murielle Girard, Sylvie Bisser, Bertrand Courtioux, Claudine Vermot-Desroches, Bernard Bouteille, John Wijdenes, Jean-Louis Preud'homme & Marie-Odile Jauberteau. (2003) In vitro induction of microglial and endothelial cell apoptosis by cerebrospinal fluids from patients with human African trypanosomiasis. International Journal for Parasitology 33:7, pages 713-720.
Crossref
John D Lonsdale-Eccles & Dennis J Grab. (2002) Trypanosome hydrolases and the blood–brain barrier. Trends in Parasitology 18:1, pages 17-19.
Crossref
S Bisser, V Lejon, P.M Preux, B Bouteille, A Stanghellini, M.O Jauberteau, P Büscher & M Dumas. (2002) Blood–cerebrospinal fluid barrier and intrathecal immunoglobulins compared to field diagnosis of central nervous system involvement in sleeping sickness. Journal of the Neurological Sciences 193:2, pages 127-135.
Crossref
Harry P de Koning. (2001) Transporters in African trypanosomes: role in drug action and resistance. International Journal for Parasitology 31:5-6, pages 512-522.
Crossref
Wei Zheng. (2001) Toxicology of choroid plexus: Special reference to metal-induced neurotoxicities. Microscopy Research and Technique 52:1, pages 89-103.
Crossref
Luc Stoppini, Pierre-Alain Buchs, Reto Brun, Dominique Muller, Sophie Duport, Lorena Parisi & Thomas Seebeck. (2000) Infection of organotypic slice cultures from rat central nervous tissue with Trypanosoma brucei brucei. International Journal of Medical Microbiology 290:1, pages 105-113.
Crossref
N. Quan, J.D.M. Mhlanga, M.B. Whiteside, K. Kristensson & M. Herkenham. (2000) Chronic sodium salicylate treatment exacerbates brain neurodegeneration in rats infected with Trypanosoma brucei. Neuroscience 96:1, pages 181-194.
Crossref
S. Chianella, M. Semprevivo, Z.-C. Peng, D. Zaccheo, M. Bentivoglio & G. Grassi-Zucconi. (1999) Microglia activation in a model of sleep disorder: an immunohistochemical study in the rat brain during Trypanosoma brucei infection. Brain Research 832:1-2, pages 54-62.
Crossref
V. W. Pentreath. 1999. Progress in Human African Trypanosomiasis, Sleeping Sickness. Progress in Human African Trypanosomiasis, Sleeping Sickness 105 117 .
V Lejon, P Büscher, E Magnus, A Moons, I Wouters & N Van Meirvenne. (1998) A semi-quantitative ELISA for detection of Trypanosoma brucei gambiense specific antibodies in serum and cerebrospinal fluid of sleeping sickness patients. Acta Tropica 69:2, pages 151-164.
Crossref
N. Khonde, J. Pépin & B. Mpia. (1997) A seven days course of eflornithine for relapsing Trypanosoma brucei gambiense sleeping sickness. Transactions of the Royal Society of Tropical Medicine and Hygiene 91:2, pages 212-213.
Crossref
V. W. Pentreath, R. A. Alafiatayo, B. Crawley, F. Doua & E. A. Oppenheim. (2009) Endotoxins in the blood and cerebrospinal fluid of patients with African sleeping sickness. Parasitology 112:1, pages 67-73.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.