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Annals of Tropical Medicine & Parasitology Volume 94, 2000 - Issue 3
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Original Articles

Comparative efficacy of chloroquine plus chlorpheniramine alone and in a sequential combination with sulfadoxine-pyrimethamine, for the treatment of acute, uncomplicated, falciparum malaria in children

A. SowunmiDepartment of Pharmacology and Therapeutics and Postgraduate Institute for Medical Research and Training, University of Ibadan, Ibadan, NigeriaCorrespondence[email protected]
,
F. A. FehintolaDepartment of Pharmacology and Therapeutics and Postgraduate Institute for Medical Research and Training, University of Ibadan, Ibadan, Nigeria
,
A. A. AdedejiDepartment of Pharmacology and Therapeutics and Postgraduate Institute for Medical Research and Training, University of Ibadan, Ibadan, Nigeria
,
A. G. FaladeDepartment of Paediatrics, University of Ibadan, Ibadan, Nigeria
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C. O. FaladeDepartment of Pharmacology and Therapeutics and Postgraduate Institute for Medical Research and Training, University of Ibadan, Ibadan, Nigeria
,
O. O. AkinyinkaDepartment of Paediatrics, University of Ibadan, Ibadan, Nigeria
&
A. M. J. OduolaDepartment of Pharmacology and Therapeutics and Postgraduate Institute for Medical Research and Training, University of Ibadan, Ibadan, Nigeria
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Pages 209-217 | Received 28 Feb 2000, Accepted 06 Mar 2000, Published online: 15 Nov 2016

Citations (13)

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Read on this site (4)

A. Sowunmi, B. A. Fateye, A. A. Adedeji, F. A. Fehintola, G. O. Gbotosho, T. C. Happi & A. M. J. Oduola. (2005) Predictors of the failure of treatment with chloroquine plus chlorpheniramine, in children with acute, uncomplicated, Plasmodium falciparum malaria. Annals of Tropical Medicine & Parasitology 99:4, pages 331-338.
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O OLAYEMI, FA FEHINTOLA, A OSUNGBADE, CO AIMAKHU, ES UDOH & AR ADENIJI. (2003) Pattern of chloroquine-induced pruritus in antenatal patients at the University College Hospital, Ibadan. Journal of Obstetrics and Gynaecology 23:5, pages 490-495.
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A. Sowunmi, A. A. Adedeji, C. O. Sowunmi, C. O. Falade, A. G. Falade, B. Ohaeri, T. C. Happi & A. M. J. Oduola. (2001) Clinical characteristics and disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. Annals of Tropical Medicine & Parasitology 95:1, pages 7-18.
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A. Sowunmi, A. A. Adedeji, C. O. Sowunmi, A. G. Falade, A. O. Sijuade & A. M. J. Oduola. (2000) Comparative clinical characteristics and response to oral antimalarial therapy of children with and without Plasmodium falciparum hyperparasitaemia in an endemic area. Annals of Tropical Medicine & Parasitology 94:6, pages 549-558.
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Articles from other publishers (9)

Bing Gan, Leiye Yu, Haifeng Yang, Haizhan Jiao, Bin Pang, Yian Chen, Chen Wang, Rui Lv, Hongli Hu, Zhijian Cao & Ruobing Ren. (2023) Mechanism of agonist-induced activation of the human itch receptor MRGPRX1. PLOS Biology 21:6, pages e3001975.
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Wook-Joo Lee & Won-Sik Shim. (2023) Rg3-enriched Korean red ginseng alleviates chloroquine-induced itch and dry skin pruritus in an MrgprA3-dependent manner in mice. Integrative Medicine Research 12:1, pages 100916.
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Wook-Joo Lee, Young-Sik Kim & Won-Sik Shim. (2018) Korean Red Ginseng extract and ginsenoside Rg3 have anti-pruritic effects on chloroquine-induced itch by inhibition of MrgprA3/TRPA1-mediated pathway. Journal of Ginseng Research 42:4, pages 470-475.
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H. R. Moser & G. J. Giesler. (2014) Characterization of pruriceptive trigeminothalamic tract neurons in rats. Journal of Neurophysiology 111:8, pages 1574-1589.
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Kush N. Patel, Qin Liu, Sonya Meeker, Bradley J. Undem & Xinzhong Dong. (2011) Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch. PLoS ONE 6:5, pages e20559.
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Kush N. Patel & Xinzhong Dong. (2010) Itch: Cells, Molecules, and Circuits. ACS Chemical Neuroscience 2:1, pages 17-25.
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Qin Liu, Zongxiang Tang, Lenka Surdenikova, Seungil Kim, Kush N. Patel, Andrew Kim, Fei Ru, Yun Guan, Hao-Jui Weng, Yixun Geng, Bradley J. Undem, Marian Kollarik, Zhou-Feng Chen, David J. Anderson & Xinzhong Dong. (2009) Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus. Cell 139:7, pages 1353-1365.
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TO Ogungbamigbe, O Ojurongbe, PS Ogunro, BM Okanlawon & SO Kolawole. (2008) Chloroquine resistant Plasmodium falciparum malaria in Osogbo Nigeria: efficacy of amodiaquine + sulfadoxine-pyrimethamine and chloroquine + chlorpheniramine for treatment. Memórias do Instituto Oswaldo Cruz 103:1, pages 79-84.
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A. Sowunmi, A.G. Falade, A.A. Adedeji, A.I. Ayede, B.A. Fateye, C.O. Sowunmi & A.M.J. Oduola. (2001) Comparative Plasmodium falciparum Kinetics during Treatment with Amodiaquine and Chloroquine in Children. Clinical Drug Investigation 21:5, pages 371-381.
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