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Original Articles

Exposure to Subcutaneously Implanted Uranium Dioxide Impairs Bone Formation

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Pages 320-325 | Received 27 Sep 2000, Accepted 23 Mar 2001, Published online: 05 Apr 2010

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Melissa A McDiarmid, Marianne Cloeren, Joanna M Gaitens, Stella Hines, Elizabeth Streeten, Richard J. Breyer$suffix/text()$suffix/text(), Clayton H. Brown, Marian Condon, Tracy Roth, Marc Oliver, Lawrence Brown, Moira Dux, Michael R. Lewin-Smith, Frederick Strathmann, Maria A. Velez-Quinones & Patricia Gucer. (2018) Surveillance results and bone effects in the Gulf War depleted uranium-exposed cohort. Journal of Toxicology and Environmental Health, Part A 81:20, pages 1083-1097.
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M. A. McDiarmid, S. M. Engelhardt, C. D. Dorsey, M. Oliver, P. Gucer, J. M. Gaitens, R. Kane, A. Cernich, B. Kaup, D. Hoover, A. A. Gaspari, M. Shvartsbeyn, L. Brown & K. S. Squibb. (2011) Longitudinal Health Surveillance in a Cohort of Gulf War Veterans 18 Years After First Exposure to Depleted Uranium. Journal of Toxicology and Environmental Health, Part A 74:10, pages 678-691.
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M. A. McDiarmid, S. M. Engelhardt, C. D. Dorsey, M. Oliver, P. Gucer, P. D. Wilson, R. Kane, A. Cernich, B. Kaup, L. Anderson, D. Hoover, L. Brown, R. Albertini, R. Gudi & K. S. Squibb. (2008) Surveillance Results of Depleted Uranium–Exposed Gulf War I Veterans: Sixteen Years of Follow-Up. Journal of Toxicology and Environmental Health, Part A 72:1, pages 14-29.
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Marjorie Monleau, Eric Blanchardon, Marie Claraz, François Paquet & Valérie Chazel. (2006) The Effect of Repeated Inhalation on the Distribution of Uranium in Rats. Journal of Toxicology and Environmental Health, Part A 69:17, pages 1629-1649.
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Articles from other publishers (28)

Joanna M. Gaitens, Melissa A. McDiarmid, Katherine S. Squibb, Marian Condon, Jessica F. Hoffman & John F. Kalinich. 2003. Patty's Toxicology. Patty's Toxicology 1 59 .
Tatiana Gritsaenko, Valérie Pierrefite-Carle, Gaëlle Creff, Bastien Simoneau, Agnès Hagège, Delphine Farlay, Sophie Pagnotta, François Orange, Xavier Jaurand, Christophe Den Auwer, Georges F. Carle & Sabine Santucci-Darmanin. (2021) Low doses of uranium and osteoclastic bone resorption: key reciprocal effects evidenced using new in vitro biomimetic models of bone matrix. Archives of Toxicology 95:3, pages 1023-1037.
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Minghao Ma, Ruixia Wang, Lining Xu, Ming Xu & Sijin Liu. (2020) Emerging health risks and underlying toxicological mechanisms of uranium contamination: Lessons from the past two decades. Environment International 145, pages 106107.
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Deanna N. Grimstead, Amy E. Clark & Adam Rezac. (2017) Uranium and Vanadium Concentrations as a Trace Element Method for Identifying Diagenetically Altered Bone in the Inorganic Phase. Journal of Archaeological Method and Theory 25:3, pages 689-704.
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Yuhui Hao, Rui Gao, Binghui Lu, Yonghong Ran, Zhangyou Yang, Jing Liu & Rong Li. (2018) Ghrelin protects against depleted uranium-induced bone damage by increasing osteoprotegerin/RANKL ratio. Toxicology and Applied Pharmacology 343, pages 62-70.
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Tatiana Gritsaenko, Valérie Pierrefite-Carle, Thomas Lorivel, Véronique Breuil, Georges F. Carle & Sabine Santucci-Darmanin. (2017) Natural uranium impairs the differentiation and the resorbing function of osteoclasts. Biochimica et Biophysica Acta (BBA) - General Subjects 1861:4, pages 715-726.
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Yann Guéguen, Laurence Roy, Sabine Hornhardt, Christophe Badie, Janet Hall, Sarah Baatout, Eileen Pernot, Ladislav Tomasek, Olivier Laurent, Teni Ebrahimian, Chrystelle Ibanez, Stephane Grison, Sylwia Kabacik, Dominique Laurier & Maria Gomolka. (2017) Biomarkers for Uranium Risk Assessment for the Development of the CURE (Concerted Uranium Research in Europe) Molecular Epidemiological Protocol. Radiation Research 187:1, pages 107-127.
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Thi-Ngoc Suong Huynh, Claude Vidaud & Agnès Hagège. (2016) Investigation of uranium interactions with calcium phosphate-binding proteins using ICP/MS and CE-ICP/MS. Metallomics 8:11, pages 1185-1192.
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Michael Dermience, Georges Lognay, Françoise Mathieu & Philippe Goyens. (2015) Effects of thirty elements on bone metabolism. Journal of Trace Elements in Medicine and Biology 32, pages 86-106.
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Elias Fattal, Nicolas Tsapis & Guillaume Phan. (2015) Novel drug delivery systems for actinides (uranium and plutonium) decontamination agents. Advanced Drug Delivery Reviews 90, pages 40-54.
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Xabier Arzuaga, Martin Gehlhaus & Jamie Strong. (2015) Modes of action associated with uranium induced adverse effects in bone function and development. Toxicology Letters 236:2, pages 123-130.
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A.C. Callan, A. Devine, L. Qi, J.C. Ng & A.L. Hinwood. (2015) Investigation of the relationship between low environmental exposure to metals and bone mineral density, bone resorption and renal function. International Journal of Hygiene and Environmental Health 218:5, pages 444-451.
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Grégory Chatelain, Damien Bourgeois, Johann Ravaux, Olivier Averseng, Claude Vidaud & Daniel Meyer. (2014) Incorporation of uranium into a biomimetic apatite: physicochemical and biological aspects. JBIC Journal of Biological Inorganic Chemistry 20:3, pages 497-507.
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Grégory Chatelain, Damien Bourgeois, Johann Ravaux, Olivier Averseng, Claude Vidaud & Daniel Meyer. (2013) Alternate dipping preparation of biomimetic apatite layers in the presence of carbonate ions. Biomedical Materials 9:1, pages 015003.
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Ndéye Marième Wade-Gueye, Olivia Delissen, Patrick Gourmelon, Jocelyne Aigueperse, Isabelle Dublineau & Maâmar Souidi. (2012) Chronic exposure to natural uranium via drinking water affects bone in growing rats. Biochimica et Biophysica Acta (BBA) - General Subjects 1820:7, pages 1121-1127.
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Claude Vidaud, Damien Bourgeois & Daniel Meyer. (2012) Bone as Target Organ for Metals: The Case of f-Elements. Chemical Research in Toxicology 25:6, pages 1161-1175.
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Melissa A. McDiarmid, Joanna M. Gaitens & Katherine S. Squibb. 2003. Patty's Toxicology. Patty's Toxicology 769 816 .
Erika Mitchell, Seth Frisbie & Bibudhendra Sarkar. (2011) Exposure to multiple metals from groundwater—a global crisis: Geology, climate change, health effects, testing, and mitigation. Metallomics 3:9, pages 874.
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Sara E. Wagner, James B. Burch, Matteo Bottai, Susan M. Pinney, Robin Puett, Dwayne Porter, John E. Vena & James R. Hébert. (2010) Hypertension and hematologic parameters in a community near a uranium processing facility. Environmental Research 110:8, pages 786-797.
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R. Racine, L. Grandcolas, S. Grison, J. Stefani, O. Delissen, P. Gourmelon, G. Veyssière & M. Souidi. (2010) Cholesterol 7α-hydroxylase (CYP7A1) activity is modified after chronic ingestion of depleted uranium in the rat. The Journal of Steroid Biochemistry and Molecular Biology 120:1, pages 60-66.
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Jason M. Seery, John M. Valosen, John H. Phillips, Dirk L. Slade, Andrea B. Seery, Mary A. Parham, Arthur B. Chasen, Paul J. Cutting & Jose M. Pizarro. (2009) Effects of Metal Fragments on Nerve Healing in Extremity Injuries Using a Rat Peroneal Nerve Model. Journal of the American College of Surgeons 209:2, pages 278-283.
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S. Milgram, M. Carrière, L. Malaval & B. Gouget. (2008) Cellular accumulation and distribution of uranium and lead in osteoblastic cells as a function of their speciation. Toxicology 252:1-3, pages 26-32.
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M M. Pujadas Bigi & A M. Ubios. (2007) CATCH-UP OF DELAYED TOOTH ERUPTION ASSOCIATED WITH URANIUM INTOXICATION. Health Physics 92:4, pages 345-348.
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Valérie Chazel, Pascale Houpert & François Paquet. 2006. Depleted Uranium. Depleted Uranium 21 53 .
Marianela Lewicki, Hugo Paez & Patricia M. Mandalunis. (2006) Effect of lithium carbonate on subchondral bone in sexually mature Wistar rats. Experimental and Toxicologic Pathology 58:2-3, pages 197-201.
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C. B. Bozal, A. B. Martinez, R. L. Cabrini & A. M. Ubios. (2005) Effect of ethane-1-hydroxy-1,1-bisphosphonate (EHBP) on endochondral ossification lesions induced by a lethal oral dose of uranyl nitrate. Archives of Toxicology 79:8, pages 475-481.
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D. Brugge, J.L. deLemos & B. Oldmixon. (2005) Exposure Pathways and Health Effects Associated with Chemical and Radiological Toxicity of Natural Uranium: A Review. Reviews on Environmental Health 20:3.
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Päivi Kurttio, Hannu Komulainen, Aila Leino, Laina Salonen, Anssi Auvinen & Heikki Saha. (2005) Bone as a Possible Target of Chemical Toxicity of Natural Uranium in Drinking Water. Environmental Health Perspectives 113:1, pages 68-72.
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