5
Views
73
CrossRef citations to date
0
Altmetric
Original Articles

Light and Electron Microscope Study of Chlorobiphenyl Poisoning

In Mouse and Monkey Liver

Pages 620-632 | Received 27 Jan 1970, Accepted 18 Mar 1970, Published online: 01 May 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Stephanie A. Lister, Barry J. Connell, Ih Chu & Amreek Singh. (2006) PCB 105-induced ultrastructural alterations in the rat liver: A stereological study. Toxicological & Environmental Chemistry 88:2, pages 309-317.
Read now
Amreek Singh, Cornelia Gilroy, Ih Chu & David C. Villeneuve. (1997) Toxicity of PCB 105 in the Rat Liver: An Ultrastructural and Biochemical Study. Ultrastructural Pathology 21:2, pages 143-151.
Read now
Amreek Singh, Ih Chu & David C. Villeneuve. (1996) Subchronic Toxicity of 2,4,4′-Trichlorobiphenyl in the Rat Liver: An Ultrastructural and Biochemical Study. Ultrastructural Pathology 20:3, pages 275-284.
Read now
PatriciaA. Talcott & LorenD. Koller. (1983) The effect of inorganic lead and/or a polychlorinated biphenyl on the developing immune system of mice. Journal of Toxicology and Environmental Health 12:2-3, pages 337-352.
Read now
Amreek Singh, V. E. O. Valli, L. Ritter & D. C. Villeneuve. (1981) Ultrastructural Alterations in the Liver of Rats Fed Photomirex (8-Monohydromirex). Pathology 13:3, pages 487-496.
Read now
Louis Kasza, MorrisA. Weinberger, Celester Carter, DavidE. Hinton, BenjaminF. Trump & EmilioA. Brouwer. (1976) Acute, subacute, and residual effects of polychlorinated biphenyl (PCB) in rats. II. Pathology and electron microscopy of liver and serum enzyme study. Journal of Toxicology and Environmental Health 1:5, pages 689-703.
Read now
D. B. Peakall & R. W. Risebrough. (1975) PCB's and their environmental effects. C R C Critical Reviews in Environmental Control 5:4, pages 469-508.
Read now
Griffith E. Quinby. (1974) To Bi or to Di. Archives of Environmental Health: An International Journal 28:6, pages 359-360.
Read now
Renate D. Kimbrough, M. M. Barnes & J. B. Greig. (1973) The Toxicity of Polychlorinated Polycyclic Compounds and Related Chemicals. CRC Critical Reviews in Toxicology 2:4, pages 445-498.
Read now
Renate D. Kimbrough, Ralph E. Linder & Thomas B. Gaines. (1972) Morphological Changes in Livers of Rats Fed Polychlorinated Biphenyls. Archives of Environmental Health: An International Journal 25:5, pages 354-364.
Read now
Renate D. Kimbrough. (1972) Toxicity of Chlorinated Hydrocarbons and Related Compounds. Archives of Environmental Health: An International Journal 25:2, pages 125-131.
Read now

Articles from other publishers (62)

. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 28 .
Yuval Ramot, Abraham Nyska, Warren Lieuallen, Alex Maly, Gordon Flake, Grace E. Kissling, Amy Brix, David E. Malarkey & Michelle J. Hooth. (2009) Inflammatory and chloracne-like skin lesions in B6C3F1 mice exposed to 3,3′,4,4′-tetrachloroazobenzene for 2 years. Toxicology 265:1-2, pages 1-9.
Crossref
Marı́a Cristina Taira, Marta Blanca Mazzetti, Sandra Marcela Lelli & Leonor Carmen San Martı́n de Viale. (2004) Glycogen metabolism and glucose transport in experimental porphyria. Toxicology 197:2, pages 164-174.
Crossref
Thomas L. Gallant, Amreek Singh & Ih Chu. (2000) PCB 118 induces ultrastructural alterations in the rat liver. Toxicology 145:2-3, pages 127-134.
Crossref
D.L. Arnold, F. Bryce, R. Stapley, P.F. McGuire, D. Burns, J.R. Tanner & K. Karpinski. (1993) Toxicological consequences of aroclor 1254 ingestion by female rhesus (macaca mulatta) monkeys. Part 1A. Prebreeding phase: Clinical health findings. Food and Chemical Toxicology 31:11, pages 799-810.
Crossref
Chandikumar S. Elangbam, Charles W. Qualls & Anthony W. Confer. (1991) Evaluation of ultrastructural hepatic response to environmental toxicants in wild cotton rats (Sigmodon hispidus). Bulletin of Environmental Contamination and Toxicology 47:2, pages 321-328.
Crossref
Günter Purschke, Margret Hagens & Wilfried Westheide. (1991) Ultrahistopathology of enchytraeid oligochaetes (annelida) after exposure to pesticides—A means of identification of sublethal effects?. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 100:1-2, pages 119-122.
Crossref
Angela Köhler. (1990) Identification of contaminant-induced cellular and subcellular lesions in the liver of flounder (Platichthys flesus L.) caught at differently polluted estuaries. Aquatic Toxicology 16:4, pages 271-293.
Crossref
Angela Köhler. (1989) Regeneration of contaminant-induced liver lesions in flounder — experimental studies towards the identification of cause-effect relationships. Aquatic Toxicology 14:3, pages 203-232.
Crossref
ERNEST E. McCONNELL. 1989. Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products. Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products 161 193 .
Feroze N. Ghadially. 1988. Ultrastructural Pathology of the Cell and Matrix. Ultrastructural Pathology of the Cell and Matrix 413 571 .
M Wilbrink, J De Vries, N.P.E Vermeulen, C Janse & T.A De Vlieger. (1987) Effects of dihalogenated biphenyls on various functional parameters in the pond snail Lymnaea stagnalis. Comparative Biochemistry and Physiology Part A: Physiology 87:4, pages 1025-1031.
Crossref
Arnold Schecter. (1986) The Binghamton state office building PCB, dioxin and dibenzofuran electrical transformer incident: 1981–1986. Chemosphere 15:9-12, pages 1273-1280.
Crossref
H.K. Reitze & K.A. Seitz. (1985) Light and electron microscopical changes in the liver of mice following treatment with aminotriazole. Experimental pathology 27:1, pages 17-31.
Crossref
Arleen B. Rifkind, Adolfo FirpoJr.Jr. & Daniel R. Alonso. (1984) Coordinate induction of cytochrome P-448 mediated mixed function oxidases and histopathologic changes produced acutely in chick embryo liver by polychlorinated biphenyl congeners. Toxicology and Applied Pharmacology 72:2, pages 343-354.
Crossref
Leander Tryphonas, John Truelove, Zofia Zawidzka, James Wong, Jos Mes, Sylvia Charbonneau, Donald L. Grant & James S. Campbell. (2016) Polychlorinated biphenyl (PCB) Toxicity in Adult Cynomolgus Monkeys (M. fascicularis): A Pilot Study. Toxicologic Pathology 12:1, pages 10-25.
Crossref
Masahiro Kikuchi. (2013) Autopsy of patients with yusho. American Journal of Industrial Medicine 5:1-2, pages 19-30.
Crossref
Monika Baumann, Erhard Deml, Ekkehard Sch�ffer & Helmut Greim. (1983) Effects of polychlorinated biphenyls at low dose levels in rats. Archives of Environmental Contamination and Toxicology 12:5, pages 509-515.
Crossref
K.A. Tarrant, P.J. Bunyan, P.I. Stanley & G.E. Westlake. (1983) The effects of 1,1-di(p-chlorophenyl)-2-chloroethylene (DDMU) on hepatic morphology of Japanese quail. Toxicology and Applied Pharmacology 67:2, pages 184-192.
Crossref
Yoshimasa Nishihara & Kozo Utsumi. (1982) Effects of polychlorinated biphenyls (Kanechlor-400) on the potassium compartmentation and glucose permeability of human erythrocyte membranes. Bulletin of Environmental Contamination and Toxicology 29:2, pages 208-213.
Crossref
Th. Helder. 1982. Chlorinated Dioxins & Related Compounds. Chlorinated Dioxins & Related Compounds 455 462 .
M. Biocca, B.N. Gupta, K. Chae, J.D. McKinney & J.A. Moore. (1981) Toxicity of selected symmetrical hexachlorobiphenyl isomers in the mouse. Toxicology and Applied Pharmacology 58:3, pages 461-474.
Crossref
Haldor T. JonssonJr.Jr., Ernest M. WalkerJr.Jr., William B. Greene, Michael D. Hughson & Gordon R. Hennigar. (1981) Effects of prolonged exposure to dietary DDT and PCB on rat liver morphology. Archives of Environmental Contamination and Toxicology 10:2, pages 171-183.
Crossref
J.F. Narbonne. (1980) Time course of induction of microsomal enzymes following dietary administration of a polychlorinated biphenyl (Phenoclor DP6). Toxicology and Applied Pharmacology 56:1, pages 1-7.
Crossref
J. F. Narbonne. (1979) Effects of age and sex on liver response to Phenoclor DP6, a polychlorinated biphenyl, in the rat. Bulletin of Environmental Contamination and Toxicology 22:1, pages 49-54.
Crossref
Martin Fleischer, R�diger Mei�, Horst Robenek & Hermann Themann. (1979) Die altersabh�ngige wirkung polychlorierter biphenyle auf die rattenleberThe age-dependent effects of polychlorinated biphenyls on rat liver. International Archives of Occupational and Environmental Health 44:1, pages 25-43.
Crossref
Marcus Wassermann, Dora Wassermann, Similica Cucos & Howard J. Miller. (1979) WORLD PCBs MAP: STORAGE AND EFFECTS IN MAN AND HIS BIOLOGIC ENVIRONMENT IN THE 1970s. Annals of the New York Academy of Sciences 320:1 Health Effect, pages 69-124.
Crossref
K.K. Kohli, B.N. Gupta, P.W. Albro, H. Mukhtar & J.D. McKinney. (1979) Biochemical effects of pure isomers of hexachlorobiphenyl: Fatty livers and cell structure. Chemico-Biological Interactions 25:2-3, pages 139-156.
Crossref
J.F. Narbonne. (1979) Turnover of liver proteins in Phenoclor DP6-treated rats. Toxicology and Applied Pharmacology 47:2, pages 245-252.
Crossref
. 1979. Potential Industrial Carcinogens and Mutagens. Potential Industrial Carcinogens and Mutagens 286 306 .
J. F. Narbonne. (1979) Effect of polychlorinated biphenyls (phenoclor DP6) onin vitro amino acid incorporation into liver proteins. Bulletin of Environmental Contamination and Toxicology 21:1, pages 322-327.
Crossref
M. Baumann. 1979. Mechanism of Toxic Action on Some Target Organs. Mechanism of Toxic Action on Some Target Organs 311 314 .
Hermann Themann, Martin Fleischer, Klaus Stahl & Rüdiger MeißHermann Themann, Martin Fleischer, Klaus Stahl & Rüdiger Meiß. 1979. Feinstrukturell-morphometrische Untersuchungen mit dem manuell-optischen Bildanalysensystem M.O.P AM 02 der Firma Kontron. Feinstrukturell-morphometrische Untersuchungen mit dem manuell-optischen Bildanalysensystem M.O.P AM 02 der Firma Kontron 31 36 .
David E. Hinton, Hans Glaumann & Benjamin F. Trump. (1978) Studies on the cellular toxicity of polychlorinated biphenyls (PCBs). Virchows Archiv B Cell Pathology 27:1, pages 279-306.
Crossref
K. Sivarajah, C. S. Franklin & W. P. Williams. (2006) Some histopathological effects of Aroclor 1254 on the liver and gonads of rainbow trout, Salmo gairdneri and carp, Cyprinus carpio . Journal of Fish Biology 13:4, pages 411-414.
Crossref
Masahiro Nishizumi. (1978) Acute toxicity of polychlorinated dibenzofurans in CF-1 mice. Toxicology and Applied Pharmacology 45:1, pages 209-212.
Crossref
J. F. Narbonne. (1978) Effect of age and sex on liver response to phenoclor DP6, a polychlorinated biphenyl, in the rat. Bulletin of Environmental Contamination and Toxicology 20:1, pages 662-667.
Crossref
V. Krampl & M. Kontseková. (1978) Effect of polychlorinated biphenyls on the elimination rate of antipyrine from plasma of rats and man. Bulletin of Environmental Contamination and Toxicology 20:1, pages 191-198.
Crossref
Shimada Tsutomu & Sato Ryo. (1978) Covalent binding in vitro of polychlorinated biphenyls to microsomal macromolecules. Biochemical Pharmacology 27:4, pages 585-593.
Crossref
Richard J. Aulerich & Robert K. Ringer. (1977) Current status of PCB toxicity to mink, and effect on their reproduction. Archives of Environmental Contamination and Toxicology 6:1, pages 279-292.
Crossref
M.J. Iatropoulos, G.R. Felt, H.P. Adams, F. Korte & F. Coulston. (1977) Chronic toxicity of 2,5,4′-trichlorobiphenyl in young rhesus monkeys. Toxicology and Applied Pharmacology 41:3, pages 629-638.
Crossref
John W. Carter & Ivan L. Cameron. (1977) Sublethal effects of a pure polychlorobiphenyl on mice. Experimental and Molecular Pathology 26:2, pages 228-250.
Crossref
Thomas Wolff & Sigrun Hesse. (1977) Species differences of mixed-function oxidase induction between rabbits and rats after pretreatment with polychlorinated biphenyls (PCB's). Biochemical Pharmacology 26:8, pages 783-787.
Crossref
Y. Takagi, T. Otake, M. Kataoka, Y. Murata, S. Aburada, S. Akasaka, K. Hashimoto, H. Uda & T. Kitaura. (1976) Studies on the transfer and distribution of [14C]polychlorinated biphenyls from maternal to fetal and suckling rats. Toxicology and Applied Pharmacology 38:3, pages 549-558.
Crossref
B. MESSNER, J. BERNDT & J. STILL. (1976) Inhibition of PEP-carboxykinase in rat liver by polychlorinated biphenyl. Nature 263:5578, pages 599-600.
Crossref
Tsutomu Shimada. (2013) Metabolic activation of [14C] polychlorinated biphenyl mixtures by rat liver microsomes. Bulletin of Environmental Contamination and Toxicology 16:1, pages 25-32.
Crossref
Kozo Ishidate & Yasuo Nakazawa. (1976) Effect of polychlorinated biphenyls (PCBs) administration on phospholipid biosynthesis in rat liver. Biochemical Pharmacology 25:11, pages 1255-1260.
Crossref
David S. Madge. (1976) Polychlorinated biphenyls and intestinal absorption of d-glucose in mice. General Pharmacology: The Vascular System 7:1, pages 45-48.
Crossref
D.J. Ecobichon & A.M. Comeau. (1975) Isomerically pure chlorobiphenyl congeners and hepatic function in the rat: Influence of position and degree of chlorination. Toxicology and Applied Pharmacology 33:1, pages 94-105.
Crossref
Yoshinori Itokawa, Ryo Tabei, Kazutaka Kamohara & Kunisato Fujiwara. (1975) Effect of simultaneous administration of polychlorinated biphenyls and alkylbenzene sulfonic acid salt in rats. Archives of Environmental Contamination and Toxicology 3:2, pages 115-131.
Crossref
W. Greb, W. Klein, F. Coulston, L. Golberg & F. Korte. (2013) Beiträge zur Ökologischen Chemie LXXXIII† In Vitro Metabolism of Polychlorinated Biphenyls-14C. Bulletin of Environmental Contamination and Toxicology 13:4, pages 424-432.
Crossref
D. Bierwolf, F. Fey, A. Graffi, E. Hecker, K. von der Helm, K. Kammer, P. N. Magee, B. Micheel, K. Munk, W. Nakahara, A. E. Pegg, R. Preussmann, T. Schramm, H. Sugano, P. F. Swann, V. Wunderlich & T. H. YosidaR. Preussmann. 1975. Geschwülste · Tumors II. Geschwülste · Tumors II 421 594 .
D. J. Ecobichon. 1975. Ecological Toxicology Research. Ecological Toxicology Research 207 214 .
D. L. Grant & W. E. J. Phillips. (1974) The effect of age and sex on the toxicity of aroclorr 1254, a polychlorinated biphenyl, in the rat. Bulletin of Environmental Contamination and Toxicology 12:2, pages 145-152.
Crossref
M.M. Hansell & D.J. Ecobichon. (1974) Effects of chemically pure chlorobiphenyls on the morphology of rat liver. Toxicology and Applied Pharmacology 28:3, pages 418-427.
Crossref
J.V. Bruckner, K.L. Khanna & H.H. Cornish. (1974) Effect of prolonged ingestion of polychlorinated biphenyls on the rat. Food and Cosmetics Toxicology 12:3, pages 323-330.
Crossref
J.V. Bruckner, K.L. Khanna & H.H. Cornish. (1974) Polychlorinated biphenyl-induced alteration of biologic parameters in the rat. Toxicology and Applied Pharmacology 28:2, pages 189-199.
Crossref
J.V. Bruckner, K.L. Khanna & H.H. Cornish. (1973) Biological responses of the rat to polychlorinated biphenyls. Toxicology and Applied Pharmacology 24:3, pages 434-448.
Crossref
Helene C. Cecil, Susan J. Harris, Joel Bitman & G. F. Fries. (1973) Polychlorinated biphenyl-induced decrease in liver vitamin A in Japanese quail and rats. Bulletin of Environmental Contamination and Toxicology 9:3, pages 179-185.
Crossref
J. R. Allen & D. H. Norback. (1973) Polychlorinated Biphenyl- and Triphenyl-Induced Gastric Mucosal Hyperplasia in Primates. Science 179:4072, pages 498-499.
Crossref
Lawrence Fishbein. (1972) Chromatographic and biological aspects of polychlorinated biphenyls. Journal of Chromatography A 68:2, pages 345-426.
Crossref
N. S. Platonow, R. M. Liptrap & H. D. Geissinger. (1972) The distribution and excretion of polychlorinated biphenyls (aroclor 1254) and their effect on urinary gonadal steroid levels in the boar. Bulletin of Environmental Contamination and Toxicology 7:6, pages 358-365.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.