20
Views
104
CrossRef citations to date
0
Altmetric
Original Articles

Chromosome Studies in Workers Exposed to Benzene or Toluene or Both

, &
Pages 373-378 | Received 31 Mar 1970, Accepted 16 Apr 1970, Published online: 29 Apr 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (15)

Luoping Zhang, David A. Eastmond & Martyn T. Smith. (2002) The Nature of Chromosomal Aberrations Detected in Humans Exposed to Benzene. Critical Reviews in Toxicology 32:1, pages 1-42.
Read now
Robert Snyder. (2000) RECENT DEVELOPMENTS IN THE UNDERSTANDING OF BENZENE TOXICITY AND LEUKEMOGENESIS. Drug and Chemical Toxicology 23:1, pages 13-25.
Read now
Robert Snyder & George F. Kali. (1994) A Perspective on Benzene Leukemogenesis. Critical Reviews in Toxicology 24:3, pages 177-209.
Read now
. (1991) Notice of Intended Changes—Toluene, Trimethylamine, and Vinyl Acetate. Applied Occupational and Environmental Hygiene 6:11, pages 966-977.
Read now
J. Mäki‐Paakkanen, K. Husgafvel‐Pursiainen, P.‐L. Kalliomäki, J. Tuominen & M. Sorsa. (1980) Toluene‐exposed workers and chromosome aberrations. Journal of Toxicology and Environmental Health 6:4, pages 775-781.
Read now
Allen Novak & The STASH Staff. (1980) The Deliberate Inhalation of Volatile Substances. Journal of Psychedelic Drugs 12:2, pages 105-122.
Read now
CarrollA. Synder, BernardD. Goldstein, Arthur Sellakumar, SandraR. Wolman, Isabel Bromberg, MartinN. Erlichman & Sidney Laskin. (1978) Hematotox1city of inhaled benzene to Sprague‐Dawley rats and AKR mice at 300 ppm. Journal of Toxicology and Environmental Health 4:4, pages 605-618.
Read now
James W. Hayden, Richard G. Peterson & James V. Bruckner. (1977) Toxicology of Toluene (Methylbenzene): Review of Current Literature. Clinical Toxicology 11:5, pages 549-559.
Read now
Thomas J. Haley. (1977) Evaluation of the Health Effects of Benzene Inhalation. Clinical Toxicology 11:5, pages 531-548.
Read now
Alessandra Forni, Giovanni Cambiaghi & Gian Carlo Secchi. (1976) Initial Occupational Exposure to Lead. Archives of Environmental Health: An International Journal 31:2, pages 73-78.
Read now
James W. Hayden, Eric G. Comstock & Betsy S. Comstock. (1976) The Clinical Toxicology of Solvent Abuse. Clinical Toxicology 9:2, pages 169-184.
Read now
JohnL. Egle$suffix/text()$suffix/text() & BetheJ. Gochberg. (1976) Respiratory retention of inhaled toluene and benzene in the dog. Journal of Toxicology and Environmental Health 1:3, pages 531-538.
Read now
Robert Snyder, James J. Kocsis & Robert Drew. (1975) Current Concepts of Chronic Benzene Toxicity. CRC Critical Reviews in Toxicology 3:3, pages 265-288.
Read now
Alessandra M. Forni, Anna Cappellini, Emma Pacifico & Enrico C. Vigliani. (1971) Chromosome Changes and Their Evolution in Subjects With Past Exposure to Benzene. Archives of Environmental Health: An International Journal 23:5, pages 385-391.
Read now

Articles from other publishers (89)

. 2024. Handbook of Solvents, Volume 2. Handbook of Solvents, Volume 2 1433 1544 .
Patrick J. Kerzic. 2003. Patty's Toxicology. Patty's Toxicology 1 58 .
. 2019. Handbook of Solvents. Handbook of Solvents 1347 1454 .
Tobias Walser, Ronnie Juraske, Evangelia Demou & Stefanie Hellweg. (2013) Indoor Exposure to Toluene from Printed Matter Matters: Complementary Views from Life Cycle Assessment and Risk Assessment . Environmental Science & Technology 48:1, pages 689-697.
Crossref
. 2014. Handbook of Solvents. Handbook of Solvents 535 633 .
. (2013) An Analysis of Historical Exposures of Pressmen to Airborne Benzene (1938–2006). The Annals of Occupational Hygiene.
Crossref
Peter F. Infante*Eula Bingham. 2003. Patty's Toxicology. Patty's Toxicology 1 68 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 40 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 2 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 318 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 24 .
Götz Alexander Westphal, Jürgen Bünger, Nadine Lichey, Dirk Taeger, Angelika Mönnich & Ernst Hallier. (2009) The benzene metabolite para-benzoquinone is genotoxic in human, phorbol-12-acetate-13-myristate induced, peripheral blood mononuclear cells at low concentrations. Archives of Toxicology 83:7, pages 721-729.
Crossref
A. L. González-Yebra, C. Kornhauser, G. Barbosa-Sabanero, E. L. Pérez-Luque, K. Wrobel & K. Wrobel. (2008) Exposure to organic solvents and cytogenetic damage in exfoliated cells of the buccal mucosa from shoe workers. International Archives of Occupational and Environmental Health 82:3, pages 373-380.
Crossref
William W. Au, Ernest Lee & David C. Christiani. (2005) Biomarker Research in Occupational Health. Journal of Occupational and Environmental Medicine 47:2, pages 145-153.
Crossref
Ayla Çelık & Etem Akbaş. (2005) Evaluation of sister chromatid exchange and chromosomal aberration frequencies in peripheral blood lymphocytes of gasoline station attendants. Ecotoxicology and Environmental Safety 60:1, pages 106-112.
Crossref
John Whysner, M Vijayaraj Reddy, Peter M Ross, Melissa Mohan & Elizabeth A Lax. (2004) Genotoxicity of benzene and its metabolites. Mutation Research/Reviews in Mutation Research 566:2, pages 99-130.
Crossref
İsmet Çok, Semra Şardaş, Ela Kadioglu & Eren Ozcagli. (2004) Assessment of DNA damage in glue sniffers by use of the alkaline comet assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 557:2, pages 131-136.
Crossref
Rogene F. Henderson. 2003. Patty's Toxicology. Patty's Toxicology.
Vilena Ka?uba, Ru?ica Rozgaj & Karmela ?entija. (2000) Cytogenetic changes in subjects occupationally exposed to benzene. Chemosphere 40:3, pages 307-310.
Crossref
�nal Egeli, Berrin Tunca, Pinar Tuncel, M�fit Kahraman, Bet�l Sevinir, G�lsah �e�ener, Hasan Batmaz, G�rler Akpinar, �igdem �imen, Taci Cang�l & Rahmi Bilaloglu. (2000) Genotoxic, hematoxic, pathological, and biochemical effects of hexane on Swiss albino rats. Teratogenesis, Carcinogenesis, and Mutagenesis 20:6, pages 329-340.
Crossref
A. Carere, A. Antoccia, D. Cimini, R. Crebelli, F. Degrassi, P. Leopardi, F. Marcon, A. Sgura, C. Tanzarella & A. Zijno. (1998) Genetic effects of petroleum fuels: II. Analysis of chromosome loss and hyperploidy in peripheral lymphocytes of gasoline station attendants. Environmental and Molecular Mutagenesis 32:2, pages 130-138.
Crossref
Martyn T. Smith & Elinor W. Fanning. (1997) Report on the workshop entitled: ?Modeling Chemically induced Leukemia?Implications for Benzene Risk Assessment?. Leukemia Research 21:5, pages 361-374.
Crossref
João Maria G.C. Silva & Renato Santos-Mello. (1996) Chromosomal aberrations in lymphocytes from car painters. Mutation Research/Genetic Toxicology 368:1, pages 21-25.
Crossref
C. C. Hedli, N. R. Rao, K. R. Reuhl, C. M. Witmer & R. Snyder. (1996) Effects of benzene metabolite treatment on granulocytic differentiation and DNA adduct formation in HL-60 cells. Archives of Toxicology 70:3-4, pages 135-144.
Crossref
Martyn T. Smith. 1996. Biological Reactive Intermediates V. Biological Reactive Intermediates V 259 266 .
B. Delahunt, P.B. Bethwaite & J.N. Nacey. (2008) Occupational risk lor renal cell carcinoma. A case‐control study based on the New Zealand Cancer Registry. British Journal of Urology 75:5, pages 578-582.
Crossref
Višnja Karačić, Ljiljana Skender, Branka Bosner‐Cucančić & Ana Bogadi‐Sare. (2007) Possible genotoxicity in low level benzene exposure. American Journal of Industrial Medicine 27:3, pages 379-388.
Crossref
Douglas McGregor. (1994) The genetic toxicology of toluene. Mutation Research/Reviews in Genetic Toxicology 317:3, pages 213-228.
Crossref
Marcus A. Jackson, H. Frank Stack & Michael D. Waters. (1993) The genetic toxicology of putative nongenotoxic carcinogens. Mutation Research/Reviews in Genetic Toxicology 296:3, pages 241-277.
Crossref
C. -L. Richer, S. Chakrabarti, M. Sen�cal-Quevillon, M. A. Duhr, X. X. Zhang & R. Tardif. (1993) Cytogenetic effects of low-level exposure to toluene, xylene, and their mixture on human blood lymphocytes. International Archives of Occupational and Environmental Health 64:8, pages 581-585.
Crossref
Renato Santos-Mello & Berenice Cavalcante. (1992) Cytogenetic studies on gas station attendants. Mutation Research/Genetic Toxicology 280:4, pages 285-290.
Crossref
Renato Santos-Mello, João C. Silva, Maria Heloisa Nunes & Maria Aparecida Braga. (1992) Cytogenetics study on coke oven workers with abnormal blood counts. Mutation Research/Genetic Toxicology 280:4, pages 261-269.
Crossref
G. Nise, B. Högstedt, I. Bratt & S. Skerfving. (1991) Cytogenetic effects in rotogravure printers exposed to toluene (and benzene). Mutation Research/Genetic Toxicology 261:3, pages 217-223.
Crossref
P B Bethwaite, N Pearce & J Fraser. (1990) Cancer risks in painters: study based on the New Zealand Cancer Registry.. Occupational and Environmental Medicine 47:11, pages 742-746.
Crossref
Lars Brandt, Ulf Kristoffersson, Håkan Olsson & Felix Mitelman. (2009) Relation between occupational exposure to organic solvents and chromosome aberrations in non‐Hodgkin's lymphoma. European Journal of Haematology 42:3, pages 298-302.
Crossref
ALESSANDRA FORNI. (2006) Benzene and Its Biologic Effects in Humans. Annals of the New York Academy of Sciences 534:1, pages 493-495.
Crossref
Awrence K. Low, J. Ralph Meeks & Carl R. Mackerer. (2016) Health Effects of the Alkylbenzenes. I. Toluene. Toxicology and Industrial Health 4:1, pages 49-75.
Crossref
Michael D. Waters, H. Frank Stack, Ann L. Brady, Paul H.M. Lohman, Lynne Haroun & Harri Vainio. (1988) Use of computerized data listings and activity profiles of genetic and related effects in the review of 195 compounds. Mutation Research/Genetic Toxicology 205:1-4, pages 295-312.
Crossref
George W. Ware. 1988. Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology 9 19 .
Kanokporn Rithidech, William W. Au, V.M. Sadagopa Ramanujam, Elbert B. WhortonJr.Jr. & Marvin S. Legator. (1987) Induction of chromosome aberrations in lymphocytes of mice after subchronic exposure to benzene. Mutation Research/Genetic Toxicology 188:2, pages 135-140.
Crossref
M. Pap & Cs. Varga. (1987) Sister-chromatid exchanges in peripheral lymphocytes of workers occupationally exposed to xylenes. Mutation Research/Genetic Toxicology 187:4, pages 223-225.
Crossref
. (2016) 4: Final Report on the Safety Assessment of Toluene. Journal of the American College of Toxicology 6:1, pages 77-120.
Crossref
William L. Marcus. (2016) Chemical of Current Interest-Benzene. Toxicology and Industrial Health 3:1, pages 205-266.
Crossref
M. Sorsa & J. W. Yager. 1987. Cytogenetics. Cytogenetics 345 360 .
Gregory L. Erexson, James L. Wilmer, William H. Steinhagen & Andrew D. Kligerman. (2006) Induction of cytogenetic damage in rodents after short‐term inhalation of benzene. Environmental Mutagenesis 8:1, pages 29-40.
Crossref
Lawrence Fishbein. (1985) An overview of environmental and toxicological aspects of aromatic hydrocarbons II. Toluene. Science of The Total Environment 42:3, pages 267-288.
Crossref
Mohy Morris Gad‐El‐Karim, V. M. Sadagopa Ramanujam, Ahmed E. Ahmed & Marvin S. Legator. (2007) Benzene myeloclastogenicity: A function of its metabolism. American Journal of Industrial Medicine 7:5-6, pages 475-484.
Crossref
Lawrence Fishbein. (1984) An overview of environmental and toxicological aspects of aromatic hydrocarbons. I. Benzene. Science of The Total Environment 40:1, pages 189-218.
Crossref
H S Brown, D R Bishop & C A Rowan. (1984) The role of skin absorption as a route of exposure for volatile organic compounds (VOCs) in drinking water.. American Journal of Public Health 74:5, pages 479-484.
Crossref
M G Clare, A Yardley-Jones, A C Maclean & B J Dean. (1984) Chromosome analysis from peripheral blood lymphocytes of workers after an acute exposure to benzene.. Occupational and Environmental Medicine 41:2, pages 249-253.
Crossref
Mohy Morris Gad-El-Karim, Barbara L. Harper & Marvin S. Legator. (1984) Modifications in the myeloclastogenic effect of benzene in mice with toluene, phenobarbital, 3-methylcholanthrene, Aroclor 1254 and SKF-525A. Mutation Research/Genetic Toxicology 135:3, pages 225-243.
Crossref
J.A. Styles & C.R. Richardson. (1984) Cytogenetic effects of benzene: dosimetric studies on rats exposed to benzene vapour. Mutation Research/Genetic Toxicology 135:3, pages 203-209.
Crossref
B. D. Goldstein. 1983. Assessment of Toxic Agents at the Workplace. Assessment of Toxic Agents at the Workplace 161 173 .
Hans F. Stich, Richard H. C. Sanandand & Miriam P. Rosin. (2006) ADAPTATION OF THE DNA‐REPAIR AND MICRONUCLEUS TESTS TO HUMAN CELL SUSPENSIONS AND EXFOLIATED CELLS*. Annals of the New York Academy of Sciences 407:1, pages 93-105.
Crossref
J. D. Jansen. 1983. The Use of Human Cells for the Evaluation of Risk from Physical and Chemical Agents. The Use of Human Cells for the Evaluation of Risk from Physical and Chemical Agents 63 76 .
Michael D. Waters, Barry E. Howard, Neil E. Garrett, H. Frank Stack & Christine M. Covone-de Serres. 1983. Chemical Mutagens. Chemical Mutagens 261 341 .
Cesare Maltoni, Barbara Conti & Giuliano Cotti. (2007) Benzene: A multipotential carcinogen. Results of long‐term bioassays performed at the bologna institute of oncology. American Journal of Industrial Medicine 4:5, pages 589-630.
Crossref
M. Bauchinger, E. Schmid, J. Dresp, J. Kolin-Gerresheim, R. Hauf & E. Suhr. (1982) Chromosome changes in lymphocytes after occupational exposure to toluene. Mutation Research/Genetic Toxicology 102:4, pages 439-445.
Crossref
H.G.S. van Raalte & P. Grasso. (1982) Hematological, myelotoxic, clastogenic, carcinogenic, and leukemogenic effects of benzene. Regulatory Toxicology and Pharmacology 2:2, pages 153-176.
Crossref
Bernard D. Goldstein & Carroll A. Snyder. 1982. Genotoxic Effects of Airborne Agents. Genotoxic Effects of Airborne Agents 277 289 .
R. R. Tice, T. F. Vogt & D. L. Costa. 1982. Genotoxic Effects of Airborne Agents. Genotoxic Effects of Airborne Agents 257 275 .
EVA MARK-VENDEL, BENKT H?GSTEDT, STAFFAN SKERFVING & FELIX MITELMAN. (2009) Location of chromosome aberrations in bone marrow cells of individuals exposed mainly to petroleum vapors. Hereditas 95:2, pages 235-237.
Crossref
B. H?GSTEDT, B. GULLBERG, E. MARK-VENDEL, F. MITELMAN & S. SKERFVING. (2009) Micronuclei and chromosome aberrations in bone marrow cells and lymphocytes of humans exposed mainly to petroleum vapors. Hereditas 94:2, pages 179-187.
Crossref
David P. Gill & Ahmed E. Ahmed. (1981) Covalent binding of [14C]benzene to cellular organelles and bone marrow nucleic acids. Biochemical Pharmacology 30:10, pages 1127-1131.
Crossref
Toluene R. von Burg. (2006) The updates represent a brief review of the often extensive literature and only pertinent studies have been included. Journal of Applied Toxicology 1:2, pages 140-140.
Crossref
Lawrence Fishbein. (1981) Carcinogenicity and mutagenicity of solvents I. Glycidyl ethers, dioxane, nitroalkanes, dimethylformamide and allyl derivatives. Science of The Total Environment 17:2, pages 97-110.
Crossref
Marvin S. Legator & Stephen J. Rinkus. 1981. Short-Term Tests for Chemical Carcinogens. Short-Term Tests for Chemical Carcinogens 483 504 .
Toshiaki Watanabe, Akira Endo, Yasuo Kato, Shogo Shima, Takao Watanabe & Masayuki Ikeda. (1980) Cytogenetics and cytokinetics of cultured lymphocytes from benzene-exposed workers. International Archives of Occupational and Environmental Health 46:1, pages 31-41.
Crossref
M. Diaz, Ana Reiser, L. Braier & J. Diez. (1980) Studies on benzene mutagenesis. I. The micronucleus test. Experientia 36:3, pages 297-299.
Crossref
Mary C. White, Peter F. Infante & Bailus WalkerJr.Jr.. (2007) Occupational exposure to benzene: A review of carcinogenic and related health effects following the U.S. Supreme Court decision. American Journal of Industrial Medicine 1:2, pages 233-243.
Crossref
Eivor Elovaara, Kari Hemminki & Harri Vainio. (1979) Effects of methylene chloride, trichloroethane, trichloroethylene, tetrachloroethylene and toluene on the development of chick embryos. Toxicology 12:2, pages 111-119.
Crossref
. 1979. Potential Industrial Carcinogens and Mutagens. Potential Industrial Carcinogens and Mutagens 445 459 .
P. Gerner-Smidt & U. Friedrich. (1978) The mutagenic effect of benzene, toluene and xylene studied by the SCE technique. Mutation Research/Genetic Toxicology 58:2-3, pages 313-316.
Crossref
James D. Green, Basil K.J. Leong & Sidney Laskin. (1978) Inhaled benzene fetotoxicity in rats. Toxicology and Applied Pharmacology 46:1, pages 9-18.
Crossref
Aranka Hudák & György Ungváry. (1978) Embryotoxic effects of benzene and its methyl derivatives: toluene, xylene. Toxicology 11, pages 55-63.
Crossref
B.J. Dean. (1978) Genetic toxicology of benzene, toluene, xylenes and phenols. Mutation Research/Reviews in Genetic Toxicology 47:2, pages 75-97.
Crossref
Robert Snyder, Eun Woo Lee, James J. Kocsis & Charlotte M. Witmer. (1977) Bone marrow depressant and leukemogenic actions of benzene. Life Sciences 21:12, pages 1709-1721.
Crossref
Kingsley Kay. 2011. Comprehensive Physiology. Comprehensive Physiology 181 191 .
F. Funes-Cravioto, B. Kolmodin-Hedman, J. Lindsten, M. Nordenskjöld, C. Zapata-Gayon, B. Lambert, E. Norberg, R. Olin & Å. Swensson. (1977) CHROMOSOME ABERRATIONS AND SISTER-CHROMATID EXCHANGE IN WORKERS IN CHEMICAL LABORATORIES AND A ROTOPRINTING FACTORY AND IN CHILDREN OF WOMEN LABORATORY WORKERS. The Lancet 310:8033, pages 322-325.
Crossref
PeterF. Infante, JosephK. Wagoner, RobertA. Rinsky & RonaldJ. Young. (1977) LEUKÆMIA IN BENZENE WORKERS. The Lancet 310:8028, pages 76-78.
Crossref
E.C. Vigliani & Alessandra Forni. (1976) Benzene and leukemia. Environmental Research 11:1, pages 122-127.
Crossref
Robert W. Miller. 1976. Tumours in Children. Tumours in Children 14 27 .
H. F. Stich, P. Lam, L. W. Lo, D. J. Koropatnick & R. H. C. San. (1975) INVITATION PAPER: THE SEARCH FOR RELEVANT SHORT TERM BIOASSAYS FOR CHEMICAL CARCINOGENS: THE TRIBULATION OF A MODERN SISYPHUS. Canadian Journal of Genetics and Cytology 17:4, pages 471-492.
Crossref
Alan Ducatman, Kurt Hirschhorn & Irving J. Selikoff. (1975) Vinyl chloride exposure and human chromosome aberrations. Mutation Research/Environmental Mutagenesis and Related Subjects 31:3, pages 163-168.
Crossref
B.J. Dean, S.M.A. Doak & H. Somerville. (1975) The potential mutagenicity of dieldrin (HEOD) in mammals. Food and Cosmetics Toxicology 13:3, pages 317-323.
Crossref
S. Skerfving, K. Hansson, C. Mangs, J. Lindsten & N. Ryman. (1974) Methylmercury-induced chromosome damage in man. Environmental Research 7:1, pages 83-98.
Crossref
. 1974. Blood. Blood 291 361 .
H. Frohberg. 1974. Environmental Quality and Safety. Environmental Quality and Safety 57 84 .
P. Alexander, G. Chomette, H. Hamperl, D. K. Hossfeld, L. G. Koss, R. Laumonier, H. F. Oettgen, M. F. Rajewsky, A. A. Sandberg, L. H. Sobin, H. Tulinius & S. WatanabeAvery A. Sandberg & Dieter K. Hossfeld. 1974. Geschwülste · Tumors I. Geschwülste · Tumors I 141 287 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.