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Scientific Communications

Benzidine Exposure as a Cause of Bladder Tumors

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Pages 1-7 | Received 13 Oct 1972, Accepted 19 Feb 1973, Published online: 02 May 2013

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Hyun-Ji Kim, In-Ae Huh, Myungsook Jung & Ho-Sang Shin. (2013) Ultra-trace level determinations of benzidine and dichlorobenzidine residues in surface water by liquid chromatography-electrospray ionization tandem mass spectrometry. International Journal of Environmental Analytical Chemistry 93:9, pages 999-1007.
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Glenn Talaska. (2003) Aromatic Amines and Human Urinary Bladder Cancer: Exposure Sources and Epidemiology. Journal of Environmental Science and Health, Part C 21:1, pages 29-43.
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King‐Thom Chung. (2000) Mutagenicity and carcinogenicity of aromatic amines metabolically produced from Azo Dyes. Journal of Environmental Science and Health, Part C 18:1, pages 51-74.
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David Michaels. (1995) When Science Isn't Enough: Wilhelm Hueper, Robert A. M. Case, and the Limits of Scientific Evidence in Preventing Occupational Bladder Cancer. International Journal of Occupational and Environmental Health 1:3, pages 278-288.
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NeilA. Littlefield, GeorgeL. Wolff & C. J. Nelson. (1985) Influence of genetic composition of test‐animal populations on chronic toxicity studies used for risk estimation. Journal of Toxicology and Environmental Health 15:3-4, pages 357-367.
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JamesM. Gentile, Sherri Brown, Marilyn Aardema, Debra Clark & Harvey Blankespoor. (1985) Modified Mutagen Metabolism in Schistosoma hematobium– Infested Organisms. Archives of Environmental Health: An International Journal 40:1, pages 5-12.
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DavidD. Rutstein, RobertJ. Mullan, ToddM. Frazier, WilliamE. Halperin, JamesM. Melius & JohnP. Sestito. (1984) Sentinel Health Events (Occupational): A Basis for Physician Recognition and Public Health Surveillance. Archives of Environmental Health: An International Journal 39:3, pages 159-168.
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Herman A. J. Schut & Andre Castonguay. (1984) Metabolism of Carcinogenic Amino Derivatives in Various Species and DNA Alkylation by Their Metabolites. Drug Metabolism Reviews 15:4, pages 753-839.
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NeilA. Littlefield, C. J. Nelson & CharlesH. Frith. (1983) Benzidine dihydrochloride: Toxicological assessment in mice during chronic exposures. Journal of Toxicology and Environmental Health 12:4-6, pages 671-685.
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Kathryn E. McLane, Jed Fisher & K. Ramakrishnan. (1983) Reductive Drug Metabolism. Drug Metabolism Reviews 14:4, pages 741-799.
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Edmund Crouch & Richard Wilson. (1979) Interspecies comparison of carcinogenic potency. Journal of Toxicology and Environmental Health 5:6, pages 1095-1118.
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Articles from other publishers (72)

Melissa L Millerick-May, Ling Wang, Carol Rice & Kenneth D Rosenman. (2021) Ongoing risk of bladder cancer among former workers at the last benzidine manufacturing facility in the USA. Occupational and Environmental Medicine 78:9, pages 625-631.
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Judy S. LaKind, Joshua Naiman & Carol J. Burns. (2020) Translation of Exposure and Epidemiology for Risk Assessment: A Shifting Paradigm. International Journal of Environmental Research and Public Health 17:12, pages 4220.
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Yair Lotan, Michel Daudon, Franck Bruyère, Glenn Talaska, Giovanni Strippoli, Richard J. Johnson & Ivan Tack. (2013) Impact of fluid intake in the prevention of urinary system diseases. Current Opinion in Nephrology and Hypertension 22, pages S1-S10.
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Robert J. Turesky & Loic Le Marchand. (2011) Metabolism and Biomarkers of Heterocyclic Aromatic Amines in Molecular Epidemiology Studies: Lessons Learned from Aromatic Amines. Chemical Research in Toxicology 24:8, pages 1169-1214.
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Zhanguang Chen, Guomin Zhang, Xi Chen, Yurui Peng, Yuejuan Lin & Simin Lu. (2011) A resonance light scattering amplification system for determination of trace amounts of benzidine in surface water. Analytical Methods 3:8, pages 1845.
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Hong–Mei Zhang, Yan–Qing Wang & Qiu–Hua Zhou. (2010) Fluorimetric study of interaction of benzidine with trypsin. Journal of Luminescence 130:5, pages 781-786.
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Ki Youn KIM, Jae Hoon ROH, Se Hoon LEE, Jong Uk WON & Chi Nyon KIM. (2009) Effects of Ethanol and Phenobarbital on Hemoglobin Adducts Formation in Rats Exposed to Benzidine and Direct Black 38. Industrial Health 47:4, pages 383-392.
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S.C. Chen, C.S. Lin, S.H. Liang & J.Y. Chuang. (2006) Detection of gentoxicity of benzidine and its derivatives with the Escherichia coli DJ 702 lacZ reversion mutagenicity assay. Letters in Applied Microbiology 43:1, pages 22-26.
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Jin-Seok Bae, Harold S. Freeman, Sarah H. Warren & Larry D. Claxton. (2006) Evaluation of new 2,2′-dimethyl-5,5′-dipropoxybenzidine- and 3,3′-dipropoxybenzidine-based direct dye analogs for mutagenic activity by use of the Salmonella/mammalian mutagenicity assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 603:2, pages 173-185.
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Ho-Sang Shin & Hye-Sil Ahn. (2006) Analysis of Benzidine and Dichlorobenzidine at Trace Levels in Water by Silylation and Gas Chromatography–Mass Spectrometry. Chromatographia 63:1-2, pages 77-84.
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