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Original Articles

Potentially Hazardous Residues of Non-Ortho Chlorine Substituted Coplanar PCBs in Human Adipose Tissue

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Pages 11-14 | Received 09 Apr 1987, Accepted 28 Jul 1987, Published online: 03 Aug 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Narayanan Kannan, DetlefE. Schulz-Bull, Gert Petrick, JanC. Duinker, Monika Macht-Hausmann & Otmar Wasserman. (1994) Toxic Chlorobiphenyls in Adipose Tissue and Whole Blood of an Occupationally/Accidentally Exposed Man and the General Population. Archives of Environmental Health: An International Journal 49:5, pages 375-383.
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Richard E. Peterson, H. Michael Theobald & Gary L. Kimmel. (1993) Developmental and Reproductive Toxicity of Dioxins and Related Compounds: Cross-Species Comparisons. Critical Reviews in Toxicology 23:3, pages 283-335.
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H.-S. Jenke, G. Michel, S. Hornhardt & J. Berndt. (1991) Protooncogene expression in rat liver by polychlorinated biphenyls (PCB). Xenobiotica 21:7, pages 945-960.
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Stephen Safe. (1991) Polychlorinated dibenzo‐p‐dioxins and related compounds: Sources, environmental distribution and risk assessment. Journal of Environmental Science and Health, Part C 9:2, pages 261-302.
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Pim De Voogt, DavidE. Wells, Lars Reutergårdh & UdoA. Th. Brinkman. (1990) Review: Biological Activity, Determination and Occurrence of Planar, Mono- and Di-Ortho PCBs. International Journal of Environmental Analytical Chemistry 40:1-4, pages 1-46.
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Shinsuke Tanabe, Narayanan Kannan, Tadaaki Wakimoto, Ryo Tatsukawa, Taku Okamoto & Yoshito Masuda. (1989) Isomer‐specific determination and toxic evaluation of potentially hazardous coplanar PCBs, dibenzofurans and dioxins in the tissues of “Yusho” PCB poisoning victim and in the causal oil. Toxicological & Environmental Chemistry 24:4, pages 215-231.
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Articles from other publishers (52)

Narayanan Kannan, Senthil Kumar Kuruthachalam, Monica Danon-Schaffer & Won Joon Shim. 2014. From Sources to Solution. From Sources to Solution 67 71 .
Ian K. Lai, Yingtao Chai, Donald Simmons, Walter H. Watson, Rommel Tan, Wanda M. Haschek, Kai Wang, Bingxuan Wang, Gabriele Ludewig & Larry W. Robertson. (2011) Dietary Selenium as a Modulator of PCB 126–Induced Hepatotoxicity in Male Sprague-Dawley Rats. Toxicological Sciences 124:1, pages 202-214.
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Jacob de Boer & Robin J Law. (2003) Developments in the use of chromatographic techniques in marine laboratories for the determination of halogenated contaminants and polycyclic aromatic hydrocarbons. Journal of Chromatography A 1000:1-2, pages 223-251.
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Annette G. Trowbridge & Deborah L. Swackhamer. (2009) Preferential biomagnification of aryl hydrocarbon hydroxylase‐ inducing polychlorinated biphenyl congeners in the Lake Michigan, USA, lower food web. Environmental Toxicology and Chemistry 21:2, pages 334-341.
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M. Mariottini, S. Aurigi & S. Focardi. (2000) Congener profile and toxicity assessment of polychlorinated biphenyls in human adipose tissue of Italians and Chileans. Microchemical Journal 67:1-3, pages 63-71.
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Jon R. Inglefield & Timothy J. Shafer. (2000) Perturbation by the PCB Mixture Aroclor 1254 of GABAA Receptor-Mediated Calcium and Chloride Responses during Maturation in Vitro of Rat Neocortical Cells. Toxicology and Applied Pharmacology 164:2, pages 184-195.
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N. Kannan. 2000. Volume 3 Anthropogenic Compounds Part K. Volume 3 Anthropogenic Compounds Part K 127 156 .
J Van Oostdam, A Gilman, E Dewailly, P Usher, B Wheatley, H Kuhnlein, S Neve, J Walker, B Tracy, M Feeley, V Jerome & B Kwavnick. (1999) Human health implications of environmental contaminants in Arctic Canada: a review. Science of The Total Environment 230:1-3, pages 1-82.
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Scott A. Jordan & M.Mark Feeley. (1999) PCB Congener Patterns in Rats Consuming Diets Containing Great Lakes Salmon: Analysis of Fish, Diets, and Adipose Tissue. Environmental Research 80:2, pages S207-S212.
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Stephen Safe. 1999. Toxicology. Toxicology 1191 1197 .
C.S. Hong, J. Xiao, B. Bush & S.D. Shaw. (1998) Environmental occurrence and potential toxicity of planar, mono-, and Di-Ortho polychlorinated biphenyls in the biota. Chemosphere 36:7, pages 1637-1651.
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Gianrico Castello & Giovanni Testini. (1997) Gas chromatographic retention index system for polychlorinated biphenyls: possibilities and limitations. Journal of Chromatography A 787:1-2, pages 215-225.
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Daniel Desaulniers, Raymond Poon, Wendy Phan, Karen Leingartner, Warren G. Foster & IH Chu. (2016) Reproductive and Thyroid Hormone Levels in Rats Following 90-Day Dietary Exposure To Pcb 28 (2,4,4'-Trichlorobiphenyl) or Pcb 77 (3,3',4,4'-Tetrachlorobiphenyl). Toxicology and Industrial Health 13:5, pages 627-638.
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Daehee Kang, Allison Tepper & Donald G. PattersonJrJr. (1997) Coplanar PCBs and the relative contribution of coplanar PCBs, PCDDs, and PCDFs to the total 2,3,7,8-TCDD toxicity equivalents in human serum. Chemosphere 35:3, pages 503-511.
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Barbara J. Bergen, William G. Nelson & Richard J. Pruell. (2009) Comparison of nonplanar and coplanar PCB congener partitioning in seawater and bioaccumulation in blue mussels ( Mytilus edulis ) . Environmental Toxicology and Chemistry 15:9, pages 1517-1523.
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G. Castello & G. Testini. (1996) Determination of retention indices of polychlorobiphenyls by using other compounds detectable by electrondashcapture detection or selected polychlorobiphenyls as the reference series. Journal of Chromatography A 741:2, pages 241-249.
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Warren G. Foster, John F. Jarrell, Edward V. Younglai, Michael G. Wade, Douglas L. Arnold & Scott Jordan. (2016) An Overview of Some Reproductive Toxicology Studies Conducted At Health Canada. Toxicology and Industrial Health 12:3-4, pages 447-459.
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Taha Sinjari, Eva Klasson‐Wehler, Agneta Oskarsson & Per Ola Darnerud. (2009) Milk Transfer and Neonatal Uptake of Coplanar Polychlorinated Biphenyl (PCB) Congeners in Mice. Pharmacology & Toxicology 78:3, pages 181-186.
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S. Marshall Adams & Mark S. GreeleyJrJr. 1996. Interconnections Between Human and Ecosystem Health. Interconnections Between Human and Ecosystem Health 91 102 .
Chikako Kiyohara, Tomio Hirohata & Yoshito Masuda. (1995) Effects of polychlorinated dibenzo-p-dioxin and dibenzofuran congeners in human lymphoblastoid cells on aryl hydrocarbon hydroxylase activity. Chemosphere 31:7, pages 3673-3680.
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F.M. Butterworth, P. Pandey, R.M. McGowen, S. Ali-Sadat & S. Walia. (1995) Genotoxicity of polychlorinated biphenyls (PCBs): recombinogenesis by biotransformation products. Mutation Research/Genetic Toxicology 342:1-2, pages 61-69.
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JS Hughes, GR Biddinger & E MonesPK Scott & KR Trowbridge. 1995. Environmental Toxicology and Risk Assessment: Third Volume. Environmental Toxicology and Risk Assessment: Third Volume 111 132 .
E.G. van der Velde, J.A. Marsman, A.P.J.M. de Jong, R. Hoogerbrugge & A.K.D. Liem. (1994) Analysis and occurrence of toxic planar PCBs, PCDDs and PCDFs in milk by use of carbosphere activated carbon. Chemosphere 28:4, pages 693-702.
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H. Michael Theobald & Richard E. Peterson. 1994. Dioxins and Health. Dioxins and Health 309 346 .
K.K. Himberg. (1993) Coplanar polychlorinated biphenyls in some Finnish food commodities. Chemosphere 27:7, pages 1235-1243.
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N. Kannan, G. Petrick, D.E. Schultz-Bull & J.C. Duinker. (1993) Chromatographic techniques in accurate analysis of chlorobiphenyls. Journal of Chromatography A 642:1-2, pages 425-434.
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K. Mayura, C.B. Spainhour, L. Howie, S. Safe & T.D. Phillips. (1993) Teratogenicity and immunotoxicity of 3,3′,4,4′,5-pentachlorobiphenyl in C57BL/6 mice. Toxicology 77:1-2, pages 123-131.
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Nobuyoshi Yamashita, Shinsuke Tanabe, James P. Ludwig, Hiroko Kurita, Matthew E. Ludwig & Ryo Tatsukawa. (1993) Embryonic abnormalities and organochlorine contamination in double-crested cormorants (Phalacrocorax auritus) and Caspian terns (Hydroprogne caspia) from the upper Great Lakes in 1988. Environmental Pollution 79:2, pages 163-173.
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Ulf G. Ahlborg, Abraham Brouwer, Marilyn A. Fingerhut, Joseph L. Jacobson, Sandra W. Jacobson, Sean W. Kennedy, Antonius A.F. Kettrup, Jan H. Koeman, Hermann Poiger, Christoffer Rappe, Stephen H. Safe, Richard F. Seegal, Jouko Tuomisto & Martin van den Berg. (1992) Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept. European Journal of Pharmacology: Environmental Toxicology and Pharmacology 228:4, pages 179-199.
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C.S. Creaser, F. Krokos & J.R. Startin. (1992) Analytical methods for the determination of non-ortho substituted chlorobiphenyls: A review. Chemosphere 25:12, pages 1981-2008.
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A. Hesso, M. Hämeilä, J. Tornaeus, A.P.J.M. de Jong & A.K.D. Liem. (1992) Polychlorinated dioxins, furans and non-ortho polychlorinated biphenyls in blood of exposed laboratory personnel. Chemosphere 25:7-10, pages 1053-1059.
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A.K.D. Liem, R.A. Baumann, A.P.J.M. de Jong, E.G. van der Velde & P. van Zoonen. (1992) Analysis of organic micropollutants in the lipid fraction of foodstuffs. Journal of Chromatography A 624:1-2, pages 317-339.
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Erkki Mannila. (1992) Synthesis and structure verification of two previously uncharacterized pentachlorobiphenyls: PCB 108 and PCB 127. Chemosphere 25:3, pages 271-276.
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Chia-Swee Hong, Brian Bush & Ju Xiao. (1992) Coplanar PCBs in fish and mussels from marine and estuarine waters of New York State. Ecotoxicology and Environmental Safety 23:1, pages 118-131.
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Kopponen Päivi, Mannila Erkki & Kärenlampi Sirpa. (1992) Induction of aryl hydrocarbon hydroxylase AHH by two previously uncharacterized pentachlorinated biphenyls in a mouse and a rat hepatoma cell line. Chemosphere 24:2, pages 201-210.
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Yoshito Masuda. (2016) Toxic Evaluation of Chlorinated Aromatic Hydrocarbons in Human Environments. Toxicology and Industrial Health 7:5-6, pages 137-141.
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David T. Williams & Guy L. LeBel. (1991) Coplanar polychlorinated biphenyl residues in human adipose tissue samples from Ontario municipalities. Chemosphere 22:11, pages 1019-1028.
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W. Sonzogni, L. Maack, T. Gibson, D. Degenhardt, H. Anderson & B. Fiore. (1991) Polychlorinated biphenyl congeners in blood of Wisconsin sport fish consumers. Archives of Environmental Contamination and Toxicology 20:1, pages 56-60.
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Erkki Sippola & Kimmo Himberg. (1991) Determination of toxic PCB congeners in biological samples by multidimensional gas chromatography-mass spectrometry (GC/GC/MS). Fresenius' Journal of Analytical Chemistry 339:7, pages 510-512.
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Chikako Kiyohara, Noriko Mohri, Tomio Hirohata, Koichi Haraguchi & Yoshito Masuda. (2009) In Vitro Effects of Methylsulfonyl Polychlorinated Biphenyls and 7,8‐Benzoflavone on Aryl Hydrocarbon Hydroxylase Activity in Human Lymphoblastoid Cells . Pharmacology & Toxicology 66:4, pages 273-276.
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Chia-Swee Hong & Brian Bush. (1990) Determination of mono- and non-ortho coplanar PCBs in fish. Chemosphere 21:1-2, pages 173-181.
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K. Norén, Ȧ Lundén, J. Sjövall & Ȧ Bergman. (1990) Coplanar polychlorinated biphenyls in Swedish human milk. Chemosphere 20:7-9, pages 935-941.
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B. Bush, R. W. Streeter & R. J. Sloan. (1990) Polychlorobiphenyl (PCB) congeners in striped bass (Morone saxatilis) from marine and estuarine waters of New York State determined by capillary gas chromatography. Archives of Environmental Contamination and Toxicology 19:1, pages 49-61.
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Narayanan Kannan, Shinsuke Tanabe, Mitsuhiro Ono & Ryo Tatsukawa. (1989) Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean. Archives of Environmental Contamination and Toxicology 18:6, pages 850-857.
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Shinsuke Tanabe, Narayanan Kannan, Minoru Fukushima, Taku Okamoto, Tadaaki Wakimoto & Ryo Tatsukawa. (1989) Persistent organochlorines in Japanese coastal waters: An introspective summary from a Far East developed nation. Marine Pollution Bulletin 20:7, pages 344-352.
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Narayanan Kannan, Shinsuke Tanabe, Taku Okamoto, Ryo Tatsukawa & David J.H. Phillips. (1989) Polychlorinated biphenyls (PCBs) in sediments in Hong Kong: A congener-specific approach to the study of coplanar PCBs in aquatic ecosystems. Environmental Pollution 62:2-3, pages 223-235.
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Narayanan Kannan, Shinsuke Tanabe, Ryo Tatsukawa & David J.H. Phillips. (1989) Persistency of highly toxic coplanar PCBs in aquatic ecosystems: Uptake and release kinetics of coplanar PCBs in green-lipped mussels (Perna viridis Linnaeus). Environmental Pollution 56:1, pages 65-76.
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Stephen Safe. (1989) Polychlorinated biphenyls (PCBs): mutagenicity and carcinogenicity. Mutation Research/Reviews in Genetic Toxicology 220:1, pages 31-47.
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Björn Brunström. (1989) Toxicity of coplanar polychlorinated biphenyls in avian embryos. Chemosphere 19:1-6, pages 765-768.
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Shinsuke Tanabe, Narayanan Kannan, Mitsuhiro Ono & Ryo Tatsukawa. (1989) Toxic threat to marine mammals: Increasing toxic potential of non-ortho and mono-ortho coplanar PCBs from land to ocean. Chemosphere 18:1-6, pages 485-490.
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N. Kannan, S. Tanabe & R. Tatsukawa. (1988) Toxic potential of non-ortho and mono-ortho coplanar PCBs in commercial PCB preparations: “2,3,7,8-T4 CDD toxicity equivalence factors approach”. Bulletin of Environmental Contamination and Toxicology 41:2, pages 267-276.
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Shinsuke Tanabe. (1988) PCB problems in the future: Foresight from current knowledge. Environmental Pollution 50:1-2, pages 5-28.
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