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Original Articles

Microsomal and cytosolic biotransformation of aflatoxin B1 in four poultry species

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Pages 734-741 | Accepted 01 Sep 2006, Published online: 15 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Mayra Carraro Di Gregorio, Keliani Bordin, Pollyana Cristina Maggio de Castro Souto, Carlos Humberto Corassin & Carlos Augusto Fernandes Oliveira. (2015) Comparative biotransformation of aflatoxin B1 in swine, domestic fowls, and humans. Toxin Reviews 34:3, pages 142-150.
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G.J. Diaz, H.W. Murcia & S.M Cepeda. (2010) Bioactivation of aflatoxin B1 by turkey liver microsomes: responsible cytochrome P450 enzymes. British Poultry Science 51:6, pages 828-837.
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GonzaloJ. Diaz, HansenW. Murcia, SandraM. Cepeda & HermanJ. Boermans. (2010) The role of selected cytochrome P450 enzymes on the bioactivation of aflatoxin B1 by duck liver microsomes. Avian Pathology 39:4, pages 279-285.
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G.J. Diaz, A. Cortés & L. Botero. (2009) Evaluation of the ability of a feed additive to ameliorate the adverse effects of aflatoxins in turkey poults. British Poultry Science 50:2, pages 240-250.
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Articles from other publishers (39)

Yuhan Wang, Xinghe Wang & Qingzhu Li. (2023) Aflatoxin B1 in poultry liver: Toxic mechanism. Toxicon 233, pages 107262.
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Vesna Jaćević, Jelena Dumanović, Suliman Y. Alomar, Radmila Resanović, Zoran Milovanović, Eugenie Nepovimova, Qinghua Wu, Tanos Celmar Costa Franca, Wenda Wu & Kamil Kuča. (2023) Research update on aflatoxins toxicity, metabolism, distribution, and detection: A concise overview. Toxicology 492, pages 153549.
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Yu Zhang, Ke-Xin Cao, Qin-Jian Niu, Jiang Deng, Ling Zhao, Mahmoud Mohamed Khalil, Niel Alexander Karrow, Kamil Kuča & Lv-Hui Sun. (2023) Alpha-class glutathione S-transferases involved in the detoxification of aflatoxin B1 in ducklings. Food and Chemical Toxicology 174, pages 113682.
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Yuting Chen, Zhaohong Lu, Boxin Li, Huanhuan Wang, Tikeng Jiang, Mei Xuan, Hui Yang, Jialong Chen, Xiaoshan Liu, Hairong Liang, Yungang Liu & Huanwen Tang. (2023) Human CYP1B1 enzyme-mediated, AhR enhanced activation of aflatoxin B1 for its genotoxicity in human cells. Toxicology Letters 373, pages 132-140.
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Surya Kanta Mishra & Bijaya Kumar Swain. 2022. Aflatoxins - Occurrence, Detection and Novel Detoxification Strategies. Aflatoxins - Occurrence, Detection and Novel Detoxification Strategies.
Avliotis Georgios & Xecotea Anastasia. (2022) The therapeutic impact of the interaction between horses and patients with mental disorders: Veterinary and psychodynamic reflexions in the clinical application of equine assisted therapy. Insights in Veterinary Science 6:1, pages 017-018.
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Lingling Wang, Qiang Huang, Jun Wu, Wanying Wu, Jun Jiang, Hongji Yan, Jieying Huang, Yu Sun & Yiqun Deng. (2022) The metabolism and biotransformation of AFB1: Key enzymes and pathways. Biochemical Pharmacology 199, pages 115005.
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Abdallah A. Ghazalah, Mamduh O. Abd-Elsamee, Kout Elkloub M. E. Moustafa, Mohamed Abdelrazik Khattab & Abd-Elrahim A. A. Rehan. (2021) Effect of Nanosilica and Bentonite as Mycotoxins Adsorbent Agent in Broiler Chickens’ Diet on Growth Performance and Hepatic Histopathology. Animals 11:7, pages 2129.
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Erhan Ayna, Zübeyir Huyut, Omer Faruk Kele&;Zabit Yener & Ramazan Bal. (2021) Protective Effect of Urtica dioica Seeds’ Extract in Experimental Chronic Aflatoxicosis in Broiler Chickens. International Journal of Poultry Science 20:6, pages 256-269.
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M. Tahir KhanM. IrfanH. AhsanS. AliA. MalikA.A. Pech-CervantesZ. CuiY.J. ZhangD.Q. Wei. (2021) CYP1A2, 2A13, and 3A4 network and interaction with aflatoxin B 1 . World Mycotoxin Journal 14:2, pages 179-189.
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Amir Ismail, Michael N. Routledge, Carlos Augusto Fernandes de Oliveira, Khalid Rehman Hakeem & Candida P. Shirima. 2021. Aflatoxins in Food. Aflatoxins in Food 1 18 .
Magdalena Buszewska-Forajta. (2020) Mycotoxins, invisible danger of feedstuff with toxic effect on animals. Toxicon 182, pages 34-53.
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Yuhua Shan. 2020. Aflatoxin B1 Occurrence, Detection and Toxicological Effects. Aflatoxin B1 Occurrence, Detection and Toxicological Effects.
Md Atiqul Haque, Yihui Wang, Zhiqiang Shen, Xiaohui Li, Muhammad Kashif Saleemi & Cheng He. (2020) Mycotoxin contamination and control strategy in human, domestic animal and poultry: A review. Microbial Pathogenesis 142, pages 104095.
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Hansen W. Murcia & Gonzalo J. Diaz. (2020) In vitro hepatic aflatoxicol production is related to a higher resistance to aflatoxin B1 in poultry. Scientific Reports 10:1.
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Benjámin Kövesi, Mátyás Cserháti, Márta Erdélyi, Erika Zándoki, Miklós Mézes & Krisztián Balogh. (2020) Lack of Dose- and Time-Dependent Effects of Aflatoxin B1 on Gene Expression and Enzymes Associated with Lipid Peroxidation and the Glutathione Redox System in Chicken. Toxins 12:2, pages 84.
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Ferenc Peles, Péter Sipos, Zoltán Győri, Walter P. Pfliegler, Federica Giacometti, Andrea Serraino, Giampiero Pagliuca, Teresa Gazzotti & István Pócsi. (2019) Adverse Effects, Transformation and Channeling of Aflatoxins Into Food Raw Materials in Livestock. Frontiers in Microbiology 10.
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Bruno Solis-Cruz, Daniel Hernandez-Patlan, Billy M. Hargis & Guillermo Tellez. 2019. Mycotoxins - Impact and Management Strategies. Mycotoxins - Impact and Management Strategies.
Gonzalo J. Diaz & Hansen W. Murcia. (2019) An unusually high production of hepatic aflatoxin B1-dihydrodiol, the possible explanation for the high susceptibility of ducks to aflatoxin B1. Scientific Reports 9:1.
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Marianne Lauwers, Siska Croubels, Ben Letor, Christos Gougoulias & Mathias Devreese. (2019) Biomarkers for Exposure as A Tool for Efficacy Testing of A Mycotoxin Detoxifier in Broiler Chickens and Pigs. Toxins 11:4, pages 187.
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Ahmed Fouad, Dong Ruan, HebatAllah El-Senousey, Wei Chen, Shouqun Jiang & Chuntian Zheng. (2019) Harmful Effects and Control Strategies of Aflatoxin B1 Produced by Aspergillus flavus and Aspergillus parasiticus Strains on Poultry: Review. Toxins 11:3, pages 176.
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Blake R. Rushing & Mustafa I. Selim. (2019) Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods. Food and Chemical Toxicology 124, pages 81-100.
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Bingxuan Jia, Song Yu, Qinghua Wu & Aibo Wu. 2019. Food Safety & Mycotoxins. Food Safety & Mycotoxins 79 100 .
Arnau Vidal, Marcel Mengelers, Shupeng Yang, Sarah De Saeger & Marthe De Boevre. (2018) Mycotoxin Biomarkers of Exposure: A Comprehensive Review. Comprehensive Reviews in Food Science and Food Safety 17:5, pages 1127-1155.
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He Wang, Ishfaq Muhammad, Wei Li, Xiaoqi Sun, Ping Cheng & Xiuying Zhang. (2018) Sensitivity of Arbor Acres broilers and chemoprevention of aflatoxin B 1 -induced liver injury by curcumin, a natural potent inducer of phase-II enzymes and Nrf2. Environmental Toxicology and Pharmacology 59, pages 94-104.
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Arya Sobhakumari, Robert H. Poppenga & Snehal Tawde. 2018. Veterinary Toxicology. Veterinary Toxicology 711 731 .
A.P. Magnoli, M.C. Rodriguez, M.L. González Pereyra, V.L. Poloni, M.F. Peralta, A.J. Nilson, R.D. Miazzo, G. Bagnis, S.M. Chiacchiera & L.R. Cavaglieri. (2017) Use of yeast (Pichia kudriavzevii) as a novel feed additive to ameliorate the effects of aflatoxin B1 on broiler chicken performance. Mycotoxin Research 33:4, pages 273-283.
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Andrea Molina Alvarado, Rebeca Zamora-Sanabria & Fabio Granados-Chinchilla. 2017. Aflatoxin-Control, Analysis, Detection and Health Risks. Aflatoxin-Control, Analysis, Detection and Health Risks.
Carlos Augusto Fernandes de Oliveira, Diane Valganon de Neeff, Ágatha Cristina de Pinho Carão & Carlos Humberto Corassin. 2017. Egg Innovations and Strategies for Improvements. Egg Innovations and Strategies for Improvements 581 596 .
Melissa Monson, Roger Coulombe & Kent Reed. (2015) Aflatoxicosis: Lessons from Toxicity and Responses to Aflatoxin B1 in Poultry. Agriculture 5:3, pages 742-777.
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Vlastimil Dohnal, Qinghua Wu & Kamil Kuča. (2014) Metabolism of aflatoxins: key enzymes and interindividual as well as interspecies differences. Archives of Toxicology 88:9, pages 1635-1644.
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Melissa S. Monson, Robert E. Settlage, Kevin W. McMahon, Kristelle M. Mendoza, Sumit Rawal, Hani S. El-Nezami, Roger A. Coulombe & Kent M. Reed. (2014) Response of the Hepatic Transcriptome to Aflatoxin B1 in Domestic Turkey (Meleagris gallopavo). PLoS ONE 9:6, pages e100930.
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Brett R. Bunderson, Ji Eun Kim, Amanda Croasdell, Kristelle M. Mendoza, Kent M. Reed & Roger A. CoulombeJr.Jr.. (2013) Heterologous expression and functional characterization of avian mu-class glutathione S-transferases. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 158:2, pages 109-116.
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Robert H. Poppenga & Snehal Tawde. 2012. Veterinary Toxicology. Veterinary Toxicology 856 886 .
Sumit Rawal, Ji Eun Kim & Roger CoulombeJr.Jr.. (2010) Aflatoxin B1 in poultry: Toxicology, metabolism and prevention. Research in Veterinary Science 89:3, pages 325-331.
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G.J. Diaz, H.W. Murcia & S.M. Cepeda. (2010) Cytochrome P450 enzymes involved in the metabolism of aflatoxin B1 in chickens and quail. Poultry Science 89:11, pages 2461-2469.
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