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International Journal of Neuroscience Volume 132, 2022 - Issue 11

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Anti-apoptotic effect of silymarin-loaded chitosan nanoparticles on hippocampal caspase-3 and Bcl-2 expression following cerebral ischemia/reperfusion injury

Seyed Reza Mokhtari Sangdehia Department of Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, Iran

Akbar Hajizadeh Moghaddama Department of Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, IranCorrespondence[email protected]

Mojtaba Ranjbarb Faculty of Biotechnology, Amol University of Special Modern Technologies, Amol, Iran

Pages 1102-1109 | Received 13 Aug 2020, Accepted 23 Nov 2020, Published online: 21 Jan 2021

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https://doi.org/10.1080/00207454.2020.1860971
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Foad Feizolahi, Ehsan Arabzadeh, Amir Sarshin, Farshad Falahi, Zahra Dehghannayeri, Ali Ali Askari, Alexei Wong, Fariba Aghaei & Mehdi Zargani. (2024) Effects of Exercise Training and L-Arginine Loaded Chitosan Nanoparticles on Hippocampus Histopathology, β-Secretase Enzyme Function, APP, Tau, Iba1and APOE-4 mRNA in Aging Rats. Neurotoxicity Research 42:2.
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Tita Hariyanti, Ria Margiana, Moaed Emran Al-Gazally, Indrajit Patra, Ghaidaa Raheem Lateef Al-Awsi, Noora Hameed, Dilrabo Kayumova, Mohammad Javed Ansari, Larry Miguel Torres-Criollo, Yasser Fakri Mustafa, Razzagh Abedi-Firouzjah & Bagher Farhood. (2023) The Protective Effects of Silymarin on the Reproductive Toxicity: A Comprehensive Review. Current Medicinal Chemistry 30:39, pages 4421-4449.
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Emre Sahin, Cemal Orhan, Nurhan Sahin, Muralidhara Padigaru, Abhijeet Morde, Mohan Lal, Nanasaheb Dhavan, Fusun Erten, Ahmet Alp Bilgic, Ibrahim Hanifi Ozercan & Kazim Sahin. (2023) Lutein/Zeaxanthin Isomers and Quercetagetin Combination Safeguards the Retina from Photo-Oxidative Damage by Modulating Neuroplasticity Markers and the Nrf2 Pathway. Pharmaceuticals 16:11, pages 1543.
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Alireza Farkhakfar, Shahin Hassanpour & Morteza Zendehdel. (2023) Resveratrol plays neuroprotective role on ketamine-induced schizophrenia-like behaviors and oxidative damage in mice. Neuroscience Letters 813, pages 137436.
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Ali Hanafi, Kazem D. Safa & Shamsali Rezazadeh. (2023) Neural Network-based Optimization of Silybum Marianum Extract-loaded Chitosan Particles: Modeling, Preparation and Antioxidant Evaluation . Current Computer-Aided Drug Design 19:1, pages 2-12.
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Qian Zhang, Meng Jia, YunFu Wang, Qun Wang & Jianping Wu. (2022) Cell Death Mechanisms in Cerebral Ischemia–Reperfusion Injury. Neurochemical Research 47:12, pages 3525-3542.
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Na Wang, Anting Xu, Hao Zhang, Yongju Zhang, Rongcui Sui, Xintai Fan, Lingxiao Hou & Li Shi. (2022) Melatonin Attenuates Cisplatin-Induced Ototoxicity via Regulating the Cell Apoptosis of the Inner Ear. Computational and Mathematical Methods in Medicine 2022, pages 1-9.
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Suraiya Saleem, Rachana Banerjee & Rajaretinam Rajesh Kannan. (2022) Chrysin-Loaded Chitosan Nanoparticle-Mediated Neuroprotection in Aβ 1–42 -Induced Neurodegenerative Conditions in Zebrafish . ACS Chemical Neuroscience 13:13, pages 2017-2034.
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Giftania Wardani, Jusak Nugraha, Mohd. Rais Mustafa, Rochmah Kurnijasanti & Sri Agus Sudjarwo. (2022) Antioxidative Stress and Antiapoptosis Effect of Chitosan Nanoparticles to Protect Cardiac Cell Damage on Streptozotocin-Induced Diabetic Rat. Oxidative Medicine and Cellular Longevity 2022, pages 1-9.
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Amal Halawa, Gehad Elshopakey, Mohamed El‐Adl, Samah Lashen, Nancy Shalaby, Ehab Eldomany, Ahmed Farghali & Shaymaa Rezk. (2021) Chitosan attenuated the neurotoxicity‐induced titanium dioxide nanoparticles in brain of adult rats. Environmental Toxicology 37:3, pages 612-626.
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Lulu Zhang, Yue Xiao, Ruijie Yang, Siyi Wang, ShuangXin Ma, Jianling Liu, Wei Xiao & Yonghua Wang. (2021) Systems pharmacology to reveal multi-scale mechanisms of traditional Chinese medicine for gastric cancer. Scientific Reports 11:1.
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Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang & Ruifen Sun. (2021) EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro . Oncology Letters 22:5.
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Anti-apoptotic effect of silymarin-loaded chitosan nanoparticles on hippocampal caspase-3 and Bcl-2 expression following cerebral ischemia/reperfusion injury

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Anti-apoptotic effect of silymarin-loaded chitosan nanoparticles on hippocampal caspase-3 and Bcl-2 expression following cerebral ischemia/reperfusion injury

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