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Original Articles

Diphenylhydantoin—Induced Hepatic Necrosis

, MD, , MD, , MD & , MD
Pages 128-134 | Published online: 07 Jul 2016

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Timi I. Edeki & David A. Brase. (1995) Phenytoin Disposition and Toxicity: Role of Pharmacogenetic and Interethnic Factors. Drug Metabolism Reviews 27:3, pages 449-469.
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Articles from other publishers (28)

Eita Sasaki, Kentaro Matsuo, Azumi Iida, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima & Tsuyoshi Yokoi. (2013) A Novel Mouse Model for Phenytoin-Induced Liver Injury: Involvement of Immune-Related Factors and P450-Mediated Metabolism. Toxicological Sciences 136:1, pages 250-263.
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Paolo Carfagna, Eleonora Pistella, Vincenzo Paravati & Pietro Serra. (2001) Arthritis as a rare side effect of phenytoin therapy. European Journal of Internal Medicine 12:5, pages 448-450.
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Marius J-M. IlarioJose E. RuizConstantine A. Axiotis. (2000) Acute Fulminant Hepatic Failure in a Woman Treated With Phenytoin and Trimethoprim-Sulfamethoxazole. Archives of Pathology & Laboratory Medicine 124:12, pages 1800-1803.
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Paul Marik. (2012) Anticonvulsant Hypersensitivity Syndrome Occurring as Sepsis with Multiorgan Dysfunction. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 19:3, pages 346-348.
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S. CHOPRA, N.J. LEVELL, G. COWLEY & J.J.H. GILKES. (1996) Systemic corticosteroids in the phenytoin hypersensitivity syndrome. British Journal of Dermatology 134:6, pages 1109-1112.
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S. CHOPRA, N.J. LEVELL, G. COWLEY & J.J.H. GILKES. (1996) Systemic corticosteroids in the phenytoin hypersensitivity syndrome. British Journal of Dermatology 134:6, pages 1109-1112.
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H. J. Zimmerman & K. G. Ishak. 1996. Drug-Induced Hepatotoxicity. Drug-Induced Hepatotoxicity 637 662 .
Ajoy K. Roy, Helen C. Mahoney & Robert A. Levine. (1993) Phenytoin-induced chronic hepatitis. Digestive Diseases and Sciences 38:4, pages 740-743.
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Richard J. Bertz & Denise L. Howrie. (2016) Diazepam by Continuous Intravenous Infusion for Status Epilepticus in Anticonvulsant Hypersensitivity Syndrome. Annals of Pharmacotherapy 27:3, pages 298-301.
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Patricia A. Howard, Phillip L. Engen & Marvin I. Dunn. (2016) Phenytoin Hypersensitivity Syndrome: A Case Report. DICP 25:9, pages 929-932.
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Gary N. Elsasser, Richard H. Hurd & Eugene J. Barone. (2016) Phenytoin Hypersensitivity Syndrome. Journal of Pharmacy Technology 7:1, pages 6-8.
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Maureen A. SmytheGreg S. Umstead. (2017) Phenytoin Hepatotoxicity: A Review of the Literature. DICP 23:1, pages 13-18.
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RJ Riley, JL Maggs, C. Lambert, NR Kitteringham & BK Park. (2012) An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.. British Journal of Clinical Pharmacology 26:5, pages 577-588.
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Emad S. Helmy & Robert Tripplet. (1988) Phenytoin syndrome developing after administration of dilantin for an enflurane-induced seizure. Journal of Oral and Maxillofacial Surgery 46:1, pages 52-58.
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Nancy G. Powers & Stephen H. Carson. (2016) Idiosyncratic Reactions to Phenytoin. Clinical Pediatrics 26:3, pages 120-124.
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Joanne N. Engel, Victor G. Mellul & David B.P. Goodman. (1986) Phenytoin hypersensitivity: A case of severe acute rhabdomyolysis. The American Journal of Medicine 81:5, pages 928-930.
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Marcia C. Fishman, Andrew H. Fischer, Peter H. Arger & Scott H. Saul. (1986) Fatal Diphenylhydantoin-Induced Hepatic Necrosis: Sonographic-Pathologic Correlation. Journal of Clinical Ultrasound 14:9, pages 722-726.
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Stephen P. Spielberg. (1986) In Vitro analysis of idiosyncratic drug reactions. Clinical Biochemistry 19:2, pages 142-144.
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Elizabeth F. Sherertz, Brian V. Jegasothy & Gerald S. Lazarus. (1985) Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Journal of the American Academy of Dermatology 12:1, pages 178-181.
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Alan P. Knutsen, Joseph Anderson, Sataya Satayaviboon & Raymond G. Slavin. (1984) Immunologic aspects of phenobarbital hypersensitivity. The Journal of Pediatrics 105:4, pages 558-563.
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Lennart Gram & Kirsten D. Bentsen. (1983) Hepatic toxicity of antiepileptic drugs: A review. Acta Neurologica Scandinavica 68, pages 81-90.
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Stephen P. Spielberg, Gary B. Gordon, David A. Blake, Daniel A. Goldstein & H. Franklin Herlong. (1981) Predisposition to Phenytoin Hepatotoxicity Assessed in Vitro. New England Journal of Medicine 305:13, pages 722-727.
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I. F. Cook, K. B. Shilkin & W. D. Reed. (2008) Phenytoin Induced Granulomatous Hepatitis. Australian and New Zealand Journal of Medicine 11:4, pages 539-541.
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Harvey W. Aiges, Fredric Daum, Madelyn Olson, Ellen Kahn & Saul Teichberg. (1980) The effects of phenobarbital and diphenylhydantoin on liver function and morphology. The Journal of Pediatrics 97:1, pages 22-26.
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James F. Koren, Gordon R. Randall, R. Samuel Kincaid & James R. Brown. (2016) Phenytoin Hypersensitivity Reaction: Hepatic necrosis. Drug Intelligence & Clinical Pharmacy 14:4, pages 252-257.
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Willis C. Maddrey. (1980) Drag-related Acute and Chronic Hepatitis. Clinics in Gastroenterology 9:1, pages 213-224.
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Sharon R. Lundin, Donald L. Uden & Russell F. Hanson. (2016) Dantrolene-Associated Hepatitis. Drug Intelligence & Clinical Pharmacy 11:5, pages 278-280.
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Terrence J. Lee, Charles N. Carney, James L. Lapis, Thomas Higgins & Harold J. Fallon. (1976) Diphenylhydantoin-Induced Hepatic Necrosis. Gastroenterology 70:3, pages 422-424.
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