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AMPHOTERICIN B

Amphotericin B

Still the ‘gold standard’ for antifungal therapy

Pages 151-166 | Published online: 07 Jul 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Briana L. Scott, Chi D. Hornik & Kanecia Zimmerman. (2020) Pharmacokinetic, efficacy, and safety considerations for the use of antifungal drugs in the neonatal population. Expert Opinion on Drug Metabolism & Toxicology 16:7, pages 605-616.
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Rhonda V. Fleming, Hagop M. Kantarjian, Rola Husni, Kenneth Rolston, Joann Lim, Issam Raad, Sherry Pierce, Jorge Cortes & Elihu Estey. (2001) Comparison of Amphotericin B Lipid Complex (ABLC) vs. AmBisome in the Treatment of Suspected or Documented Fungal Infections in Patients with Leukemia. Leukemia & Lymphoma 40:5-6, pages 511-520.
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John W. Hiemenz & Thomas J. Walsh. (1998) Lipid Formulations of Amphotericin. Journal of Liposome Research 8:4, pages 443-467.
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Articles from other publishers (47)

Elsa R. Arias, Vivian Angarita-Villamizar, Yolima Baena, Claudia Parra-Giraldo & Leon D. Perez. (2021) Phospholipid-Conjugated PEG-b-PCL Copolymers as Precursors of Micellar Vehicles for Amphotericin B. Polymers 13:11, pages 1747.
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Jinhua Zhang, Hongjiang Xu, Yuanzhen Dong, Minwei Chen, You Zhang, Wenwen Shangguan, Wenjie Zhao & Jun Feng. (2021) Design, synthesis and biological evaluation of a novel N-aminoacyl derivative of amphotericin B methyl ester as an antifungal agent. European Journal of Medicinal Chemistry 211, pages 113104.
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Angie V. Angarita-Villamizar, Elsa R. Arias, Ivonne L. Diaz & Leon D. Perez. (2021) Amphiphilic copolymers modified with oleic acid and cholesterol by combining ring opening polymerization and click chemistry with improved amphotericin B loading capacity. Journal of Polymer Research 28:1.
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Yeimy J. Rodriguez, Luis F. Quejada, Jean C. Villamil, Yolima Baena, Claudia M. Parra-Giraldo & Leon D. Perez. (2020) Development of Amphotericin B Micellar Formulations Based on Copolymers of Poly(ethylene glycol) and Poly(ε-caprolactone) Conjugated with Retinol. Pharmaceutics 12:3, pages 196.
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Thuyen Truong, Guisheng Zeng, Lin Qingsong, Lim Teck Kwang, Cao Tong, Fong Yee Chan, Yue Wang & Chaminda Jayampath Seneviratne. (2016) Comparative Ploidy Proteomics of Candida albicans Biofilms Unraveled the Role of the AHP1 Gene in the Biofilm Persistence Against Amphotericin B. Molecular & Cellular Proteomics 15:11, pages 3488-3500.
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Grzegorz Czernel, Rafał Typek, Katarzyna Klimek, Aleksandra Czuryło, Andrzej L. Dawidowicz & Mariusz Gagoś. (2016) Catalytic effect of free iron ions and heme-iron on chromophore oxidation of a polyene antibiotic amphotericin B. Journal of Molecular Structure 1111, pages 69-75.
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Santhanam Shanmughapriya, Haridevvenkatesan Sornakumari, Arumugam Lency, Senthil Kavitha & Kalimuthusamy Natarajaseenivasan. (2014) Synergistic effect of amphotericin B and tyrosol on biofilm formed by Candida krusei and Candida tropicalis from intrauterine device users. Medical Mycology 52:8, pages 853-861.
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Sarah S.W. Wong, Lakshman P. Samaranayake & Chaminda J. Seneviratne. (2014) In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules. Drug Discovery Today 19:11, pages 1721-1730.
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Chris Stockmann, Jonathan E. Constance, Jessica K. Roberts, Jared Olson, Elizabeth H. Doby, Krow Ampofo, Justin Stiers, Michael G. Spigarelli & Catherine M. T. Sherwin. (2014) Pharmacokinetics and Pharmacodynamics of Antifungals in Children and their Clinical Implications. Clinical Pharmacokinetics 53:5, pages 429-454.
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Rabkwan Chuealee, Timothy Scott Wiedmann & Teerapol Srichana. (2011) Physicochemical Properties and Antifungal Activity of Amphotericin B Incorporated in Cholesteryl Carbonate Esters. Journal of Pharmaceutical Sciences 100:5, pages 1727-1735.
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Esther Segal & Daniel Elad. 2010. Topley & Wilson's Microbiology and Microbial Infections. Topley & Wilson's Microbiology and Microbial Infections.
Mehmet Turgut, Yelda ?zsunar, Serkan ?nc?Orhan Aky?z, Mustafa B. Ertu?rul, Cengiz Tekin, Berna G?ltekin & Serhan Sakarya. (2008) Invasive fungal granuloma of the brain caused by Aspergillus fumigatus: a case report and review of the literature. Surgical Neurology 69:2, pages 169-174.
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Ran D. Goldman, Michael Ong, Jacob Wolpin, Christopher Parshuram, Gideon Koren & John Doyle. (2007) Pharmacological Risk Factors for Amphotericin B Nephrotoxicity in Children. The Journal of Clinical Pharmacology 47:8, pages 1049-1054.
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Ran D. Goldman & Gideon Koren. (2004) Amphotericin B Nephrotoxicity in Children. Journal of Pediatric Hematology/Oncology 26:7, pages 421-426.
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Ruta Petraitiene, Vidmantas Petraitis, Caron A. Lyman, Andreas H. Groll, Diana Mickiene, Joanne Peter, John Bacher, Kristin Roussillon, Melissa Hemmings, Derrek Armstrong, Nilo A. Avila & Thomas J. Walsh. (2004) Efficacy, Safety, and Plasma Pharmacokinetics of Escalating Dosages of Intravenously Administered Ravuconazole Lysine Phosphoester for Treatment of Experimental Pulmonary Aspergillosis in Persistently Neutropenic Rabbits. Antimicrobial Agents and Chemotherapy 48:4, pages 1188-1196.
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H. Vanden Bossche, M. Engelen & F. Rochette. (2003) Antifungal agents of use in animal health - chemical, biochemical and pharmacological aspects. Journal of Veterinary Pharmacology and Therapeutics 26:1, pages 5-29.
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Vidmantas Petraitis, Ruta Petraitiene, Andreas H. Groll, Kristin Roussillon, Melissa Hemmings, Caron A. Lyman, Tin Sein, John Bacher, Ihor Bekersky & Thomas J. Walsh. (2002) Comparative Antifungal Activities and Plasma Pharmacokinetics of Micafungin (FK463) against Disseminated Candidiasis and Invasive Pulmonary Aspergillosis in Persistently Neutropenic Rabbits. Antimicrobial Agents and Chemotherapy 46:6, pages 1857-1869.
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Ruta Petraitiene, Vidmantas Petraitis, Andreas H. Groll, Tin Sein, Stephen Piscitelli, Myrna Candelario, Aida Field-Ridley, Nilo Avila, John Bacher & Thomas J. Walsh. (2001) Antifungal Activity and Pharmacokinetics of Posaconazole (SCH 56592) in Treatment and Prevention of Experimental Invasive Pulmonary Aspergillosis: Correlation with Galactomannan Antigenemia. Antimicrobial Agents and Chemotherapy 45:3, pages 857-869.
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Samir BouzBouz & Janine Cossy. (2000) Enantioselective Allyltitanation. Efficient Synthesis of the C1−C14 Polyol Subunit of Amphotericin B. Organic Letters 2:25, pages 3975-3977.
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Ruta Petraitiene, Vidmantas Petraitis, Andreas H. Groll, Myrna Candelario, Tin Sein, Aaron Bell, Caron A. Lyman, Carl L. McMillian, John Bacher & Thomas J. Walsh. (1999) Antifungal Activity of LY303366, a Novel Echinocandin B, in Experimental Disseminated Candidiasis in Rabbits. Antimicrobial Agents and Chemotherapy 43:9, pages 2148-2155.
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