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Clinical Features - Review

Myths and misconceptions concerning contrast media-induced anaphylaxis: a narrative review

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Pages 259-266 | Received 14 Jul 2016, Accepted 11 Jan 2017, Published online: 25 Jan 2017

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Alan A. Peters, Johannes T. Heverhagen & Ingrid B. Boehm. (2022) Delayed hypersensitivity reaction after oral intake of non-ionic iodinated contrast medium. Acta Clinica Belgica 77:4, pages 785-786.
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Lara Chehabeddine, Tala Al Saleh, Marwa Baalbaki, Eman Saleh, Samia J. Khoury & Salem Hannoun. (2019) Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents. Critical Reviews in Toxicology 49:3, pages 262-279.
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Joo Young Lee, Minji Son, Jin Han Kang & Ui Yoon Choi. (2018) Serum interleukin-6 levels as an indicator of aseptic meningitis among children with enterovirus 71-induced hand, foot and mouth disease. Postgraduate Medicine 130:2, pages 258-263.
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Articles from other publishers (34)

Adrian A. Schmid, Martin N. Hungerbühler, Paolo Lombardo & Ingrid B. Boehm. (2024) Intradermal testing of iodinated contrast media: Should we test up to pure or with diluted compounds only?. Fundamental & Clinical Pharmacology.
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Xenofon M. Sakellariou, Christos S. Katsouras, Michail I. Papafaklis, Christos Floros, Lampros K. Michalis & Dimitri Karmpaliotis. (2023) Absolute zero-contrast percutaneous coronary interventions: An intravascular ultrasound-guided case series and literature review. Cardiovascular Revascularization Medicine.
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Paolo Lombardo, Knud Nairz & Ingrid Boehm. (2023) Why mild contrast medium-induced reactions are sometimes over-treated and moderate/severe reactions of internal organs are undertreated: a summary based on RadioComics. Insights into Imaging 14:1.
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Y. Jia, M. Szewczyk-Bieda, R. Greenhalgh & K. Drinkwater. (2023) Preventing post-contrast acute kidney injury and hypersensitivity reactions: UK national audit. Clinical Radiology 78:11, pages e898-e907.
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Ryouichi Chatani, Sakura Kondo, Tadamasa Kamimura, Shinya Suzuki, Eriko Komatsubara, Seiichi Hayashi, Masayuki Hashiguchi, Hayato Kizaki, Shungo Imai & Satoko Hori. (2023) Exploring Factors Affecting the Occurrence of Hypersensitivity Reactions Induced by Nonionic Iodine Contrast Media. The Journal of Clinical Pharmacology 63:9, pages 1002-1008.
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Richard C. Semelka & Miguel Ramalho. (2023) Gadolinium Deposition Disease. Investigative Radiology 58:8, pages 523-529.
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Rocío Sáenz de Santa María, Marina Labella, Gádor Bogas, Inmaculada Doña & María José Torres. (2023) Hypersensitivity to gadolinium-based contrast. Current Opinion in Allergy & Clinical Immunology 23:4, pages 300-306.
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David R. Koeppel & Ingrid B. Boehm. (2023) Shortage of iodinated contrast media: Status and possible chances – A systematic review. European Journal of Radiology 164, pages 110853.
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Huiyan Jiang, Yuan Li, Xiaoyan Wu, Hongming Yu, Xin Zhang, Weihong Ge & Simin Yan. (2023) Pharmacist-led iodinated contrast media infusion risk assessment service. Frontiers in Pharmacology 14.
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Heng Liu, Haiyan Qiu, Junling Liu, Lingru Wang, Li Zhao, Yaling Wang & Xue Li. (2023) Stratified assessment and warning regimen for prevention of acute adverse reactions to iodinated contrast media: results of 150,343 cases in a tertiary hospital. Medical & Biological Engineering & Computing 61:3, pages 709-720.
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Andreas J. Bircher & Kathrin Scherer Hofmeier. (2022) Akute Schwellung im Halsbereich nach iodhaltigem Kontrastmittel – der oft unerkannte Iodmumps anhand von drei Fallbeispielen. Aktuelle Dermatologie 49:01/02, pages 52-57.
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A. Talmon, Y. Tal, J. Moss, I. Hershkowitz, D. Shaham, J. Sosna & A.Y. Hershko. (2022) Clinical impact of allergy and pre-medication in CT studies with low-osmolality intravenous iodinated contrast media. Clinical Radiology 77:3, pages 210-215.
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Richard Bruen, Aaron Stirling, M. Ryan, M. Sheehan & Peter MacMahon. (2021) Shelling the myth: allergies to Iodine containing substances and risk of reaction to Iodinated contrast media. Emergency Radiology 29:1, pages 67-73.
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Ingrid B. Boehm. (2022) Classification of gadolinium-based contrast agents (GBCAs)-adverse reactions. Magnetic Resonance Imaging 85, pages 1-2.
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Honorio T. Benzon, Timothy P. Maus, Hye-Ryun Kang, David A. Provenzano, Anuj Bhatia, Felix Diehn, Ariana Nelson, Zachary L. McCormick, Benjamin P. Liu, Javier de Andres Ares, Magdalena Anitescu, Kristine Blackham, Arun Bhaskar, Silviu Brill, Jeremy Collins, Ashish Gulve, Robert W. Hurley, Young Hoon Jeon, Jee Youn Moon, Richard L. Rauck, Meghan Rodes, Ryan K. Lee, Vinil Shah, Harsha Shanthanna, Jan van Zundert, Marc Huntoon, James P. Rathmell, Mario Sanchez Borges, Steven P. Cohen & Paul A. Greenberger. (2021) The Use of Contrast Agents in Interventional Pain Procedures: A Multispecialty and Multisociety Practice Advisory on Nephrogenic Systemic Fibrosis, Gadolinium Deposition in the Brain, Encephalopathy After Unintentional Intrathecal Gadolinium Injection, and Hypersensitivity Reactions. Anesthesia & Analgesia 133:2, pages 535-552.
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Bangtao Chen, Fubing Yu, WenChieh Chen, Yong Wang & Fei Hao. (2021) Acute Urticaria in Inpatients Undergoing Non-emergent Coronary Angiography With Corticosteroid Prophylaxis: A Retrospective Study. Frontiers in Medicine 8.
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M. Zanardo, F. Sardanelli, L. Rainford, C.B. Monti, J.G. Murray, F. Secchi & A. Cradock. (2021) Technique and protocols for cardiothoracic time-resolved contrast-enhanced magnetic resonance angiography sequences: a systematic review. Clinical Radiology 76:2, pages 156.e9-156.e18.
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Eun-Young Kim, Seok Jin Choi, Jong-Lyul Ghim, Mi-Yeong Kim, Jung Eun Seol, Minkyung Oh, Chan Sun Park & Jae-Gook Shin. (2021) Associations between HLA-A, -B, and -C alleles and iodinated contrast media–induced hypersensitivity in Koreans. Translational and Clinical Pharmacology 29:2, pages 107.
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Ingrid Boehm & Martin Hungerbühler. (2020) Excretion of iodinated contrast media in human breast milk: surprising results. European Journal of Radiology 128, pages 109045.
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Patrick M Foye, Woon TK Jason, Kevin Y Zheng & Kenneth K Leong. (2021) Low incidence of vascular uptake during ganglion impar sympathetic nerve blocks for coccydynia. Indian Journal of Radiology and Imaging 30:02, pages 181-183.
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Hiroyasu Umakoshi, Takashi Nihashi, Hironori Shimamoto, Takehiro Yamada, Hiroaki Ishiguchi, Akira Takada, Naoki Hirasawa, Shunichi Ishihara, Yasuo Takehara, Shinji Naganawa, Matthew Davenport & Teruhiko Terasawa. (2020) Pharmacologic and non-pharmacologic interventions to prevent hypersensitivity reactions of non-ionic iodinated contrast media: a systematic review protocol. BMJ Open 10:3, pages e033023.
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Nicolette L. Dumas & Kendall P. Crookston. (2020) Radiologic Contrast Reactions and Transfusion Reactions: Recognition, Differentiation, and Treatment. Journal of Radiology Nursing 39:1, pages 32-38.
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Ingrid Boehm & Paolo Lombardo. (2019) Letter to the Editor: how to document adverse reactions induced by gadolinium based contrast agents? A plea for type A and type B reactions. European Radiology 30:3, pages 1755-1756.
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Rik Schrijvers, Pascal Demoly & Anca Mirela Chiriac. (2019) Premedication for Iodinated Contrast Media Induced Immediate Hypersensitivity Reactions. Current Treatment Options in Allergy 6:4, pages 538-553.
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David MacDonald. 2019. Oral and Maxillofacial Radiology. Oral and Maxillofacial Radiology 73 88 .
Paolo Lombardo, Knud Nairz & Ingrid Boehm. (2019) Patients’ safety and the “iodine allergy” – How should we manage patients with iodine allergy before they receive an iodinated contrast medium?. European Journal of Radiology 116, pages 150-151.
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Guy Topaz, Adi Karas, Nuha Kassem, Yona Kitay-Cohen, David Pereg, Lotan Shilo, Adi Zoref-Lorenz & Alon Y. Hershko. (2018) Iodinated Contrast Media Allergy in Patients Hospitalized for Investigation of Chest Pain. The Journal of Allergy and Clinical Immunology: In Practice 6:6, pages 2059-2064.
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Ingrid Böhm. (2018) Pretesting With the Injection of Small Doses of Contrast Media Is Dangerous and Should Be Omitted. Vascular and Endovascular Surgery 52:5, pages 398-399.
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Ingrid Boehm, Martin Hungerbühler & Johannes T. Heverhagen. (2018) Insight into the dynamic of gadolinium based contrast agent (GBCA) hypersensitivity: Acquisition, persistence and disappearance. Magnetic Resonance Imaging 49, pages 1-3.
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Ingrid Böhm. (2018) Iodinated X-ray contrast media in aquatic environment in general and in drinking water in particular: A possible source for the primary sensitization of patients. Chemosphere 194, pages 28-29.
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Pedro Giavina-Bianchi, Marcelo V. Aun & Jorge Kalil. (2018) Drug-induced anaphylaxis: is it an epidemic?. Current Opinion in Allergy & Clinical Immunology 18:1, pages 59-65.
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Miguel Ramalho & Joana Ramalho. (2017) Gadolinium-Based Contrast Agents. Magnetic Resonance Imaging Clinics of North America 25:4, pages 755-764.
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Ingrid Boehm, John Morelli, Knud Nairz, Patricia Silva Hasembank Keller & Johannes T. Heverhagen. (2017) Risks of contrast media applied via the gastrointestinal route. European Journal of Internal Medicine 42, pages e19-e21.
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Daniel Bell & Bruno Di Muzio. 2005. Radiopaedia.org. Radiopaedia.org.

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