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Clinical Focus: Cardiovascular Disease - Practice Pearl

Canagliflozin and cardiovascular and renal events in type 2 diabetes

Pages 149-153 | Received 16 Oct 2017, Accepted 02 Jan 2018, Published online: 12 Jan 2018

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Genya Aharon-Hananel & Itamar Raz. (2019) An evaluation of the efficacy and safety of Tofogliflozin for the treatment of type II diabetes. Expert Opinion on Pharmacotherapy 20:7, pages 781-790.
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Jiayu Lv, Yumeng Li, Shuqing Shi, Shixu Liu, Xia xu, Huaqin Wu, Bingxuan Zhang & Qingqiao Song. (2023) Frontier and Hotspot Evolution in Cardiorenal Syndrome: A Bibliometric Analysis From 2003 to 2022. Current Problems in Cardiology 48:8, pages 101238.
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Xianghong Wang, Niujian Wu, Chuanchuan Sun, Donghua Jin & Hongyun Lu. (2023) Effects of SGLT-2 inhibitors on adipose tissue distribution in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. Diabetology & Metabolic Syndrome 15:1.
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Daniel Edmonston, Matthew Sparks, Sudarshan Rajagopal & Myles Wolf. (2023) Sildenafil and Kidney Function in Heart Failure with Preserved Ejection Fraction. Kidney360 4:5, pages 631-640.
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Guoqing Huang, Mingcai Li, Yan Li & Yushan Mao. (2022) Metabolomics: A New Tool to Reveal the Nature of Diabetic Kidney Disease. Laboratory Medicine 53:6, pages 545-551.
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Xin Cao, Xiaojing Du, Heng Jiao, Quanlin An, Ruoxue Chen, Pengfei Fang, Jing Wang & Biao Yu. (2022) Carbohydrate-based drugs launched during 2000−2021. Acta Pharmaceutica Sinica B 12:10, pages 3783-3821.
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Xie Lingli & Xia Wenfang. (2022) Characteristics and molecular mechanisms through which SGLT2 inhibitors improve metabolic diseases: A mechanism review. Life Sciences 300, pages 120543.
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Ran Wei, Weihao Wang, Qi Pan & Lixin Guo. (2022) Effects of SGLT-2 Inhibitors on Vascular Endothelial Function and Arterial Stiffness in Subjects With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in Endocrinology 13.
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Eiji Kutoh, Alexandra N. Kuto, Askuka Wada, Rumi Kurihara & Rina Kojima. (2021) Regulations of Free Fatty Acids and Diabetic Parameters in Drug Naïve Subjects with Type 2 Diabetes Treated with Canagliflozin Monotherapy. Drug Research 72:02, pages 86-93.
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Suiyuan Hu, Chu Lin, Xiaoling Cai, Xingyun Zhu, Fang Lv, Lin Nie & Linong Ji. (2022) The Urinary Glucose Excretion by Sodium–Glucose Cotransporter 2 Inhibitor in Patients With Different Levels of Renal Function: A Systematic Review and Meta-Analysis. Frontiers in Endocrinology 12.
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Mariana Tilinca, Robert Tiuca, Ioan Tilea & Andreea Varga. (2021) The SGLT-2 Inhibitors in Personalized Therapy of Diabetes Mellitus Patients. Journal of Personalized Medicine 11:12, pages 1249.
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Michaele B. Manigrasso, Piul Rabbani, Lander Egaña-Gorroño, Nosirudeen Quadri, Laura FryeBoyan Zhou, Sergey Reverdatto, Lisa S. Ramirez, Stephen DansereauJinhong PanHuilin Li, Vivette D. D’AgatiRavichandran Ramasamy, Robert J. DeVitaAlexander Shekhtman & Ann Marie Schmidt. (2021) Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice. Science Translational Medicine 13:621.
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Miaobo Zhai, Xin Du, Changmei Liu & Huipu Xu. (2021) The Effects of Dapagliflozin in Patients With Heart Failure Complicated With Type 2 Diabetes: A Meta-Analysis of Placebo-Controlled Randomized Trials. Frontiers in Clinical Diabetes and Healthcare 2.
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Patrick Meagher, Robert Civitarese, Xavier Lee, Mark Gordon, Antoinette Bugyei-Twum, Jean-Francois Desjardins, Golam Kabir, Yanling Zhang, Hari Kosanam, Aylin Visram, Howard Leong-Poi, Andrew Advani & Kim A. Connelly. (2021) The Goto Kakizaki rat: Impact of age upon changes in cardiac and renal structure, function. PLOS ONE 16:6, pages e0252711.
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Yuya Itano, Hiroshi Sobajima, Norimi Ohashi, Taiga Shibata, Atsushi Fujiya, Takanobu Nagata, Masahiko Ando, Takahiro Imaizumi, Yoko Kubo, Takaya Ozeki, Takayuki Katsuno, Sawako Kato, Yoshinari Yasuda & Shoichi Maruyama. (2020) High urinary glucose is associated with improved renal prognosis in patients with diabetes mellitus. Journal of Diabetes Investigation 12:6, pages 998-1006.
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Zsolt Szekeres, Kalman Toth & Eszter Szabados. (2021) The Effects of SGLT2 Inhibitors on Lipid Metabolism. Metabolites 11:2, pages 87.
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Ichraf Slimani, Lamjed Mansour, Ismail Özdemir, Nevin Gürbüz & Naceur Hamdi. (2021) Synthesis, characterization and catalytic activity of PEPPSI-type palladium–NHC complexes. Inorganica Chimica Acta 515, pages 120043.
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Carina Kirstine Klarskov, Helga Holm Schultz, Frederik Persson, Tomas Møller Christensen, Thomas Peter Almdal, Ole Snorgaard, Katrine Bagge Hansen, Ulrik Pedersen-Bjergaard & Peter Lommer Kristensen. (2020) Study rationale and design of the EANITIATE study (EmpAgliflozin compared to NPH Insulin for sTeroId diAbeTEs) - a randomized, controlled, multicenter trial of safety and efficacy of treatment with empagliflozin compared with NPH-insulin in patients with newly onset diabetes following initiation of glucocorticoid treatment. BMC Endocrine Disorders 20:1.
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K. Melissa Hallow, David W. Boulton, Robert C. Penland, Gabriel Helmlinger, Emily H. Nieves, Daniël H. van Raalte, Hiddo L. Heerspink & Peter J. Greasley. (2020) Renal Effects of Dapagliflozin in People with and without Diabetes with Moderate or Severe Renal Dysfunction: Prospective Modeling of an Ongoing Clinical Trial. Journal of Pharmacology and Experimental Therapeutics 375:1, pages 76-91.
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Xiu Yang, Yuqian Li, Chongjian Wang, Zhenxing Mao, Wen Zhou, Lulu Zhang, Mengying Fan, Songyang Cui & Linlin Li. (2020) Meat and fish intake and type 2 diabetes: Dose–response meta-analysis of prospective cohort studies. Diabetes & Metabolism 46:5, pages 345-352.
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M.C. Gómez García, J. Franch-Nadal, J.M. Millaruelo Trillo, F.X. Cos-Claramunt, L. Avila Lachica & P. Buil Cosiales. (2020) Control glucémico y de los factores de riesgo cardiovascular en los pacientes con diabetes tipo 2 con enfermedad cardiovascular en España, y su patrón de tratamiento, en función del género: Estudio CODICE. Medicina de Familia. SEMERGEN 46:2, pages 125-135.
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Canan ERSOY. (2020) SGLT 2 inhibitors: Antidiabetic agents with promising effects beyond glucose control. Turkish Journal of Internal Medicine 2:1, pages 1-4.
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Andrew Smith, Vadim Iablokov, Mariafrancesca Mazza, Sonia Guarnerio, Vanna Denti, Mariia Ivanova, Martina Stella, Isabella Piga, Clizia Chinello, Bram Heijs, Peter A. van Veelen, Hallgrimur Benediktsson, Daniel A. Muruve & Fulvio Magni. (2020) Detecting Proteomic Indicators to Distinguish Diabetic Nephropathy from Hypertensive Nephrosclerosis by Integrating Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging with High-Mass Accuracy Mass Spectrometry. Kidney and Blood Pressure Research 45:2, pages 233-248.
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Ikaro Breder & Andrei C. Sposito. 2020. Obesity and Diabetes. Obesity and Diabetes 695 704 .
Daniela Stols-Gonçalves, G. Kees Hovingh, Max Nieuwdorp & Adriaan G. Holleboom. (2019) NAFLD and Atherosclerosis: Two Sides of the Same Dysmetabolic Coin?. Trends in Endocrinology & Metabolism 30:12, pages 891-902.
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Mikkel Jürgens, Morten Schou, Philip Hasbak, Andreas Kjær, Emil Wolsk, Bo Zerahn, Mikkel Wiberg, Niels Høgh Brandt, Peter Haulund Gæde, Peter Rossing, Jens Faber, Silvio Inzucchi, Finn Gustafsson & Caroline Michaela Kistorp. (2019) Design of a randomised controlled trial of the effects of empagliflozin on myocardial perfusion, function and metabolism in type 2 diabetes patients at high cardiovascular risk (the SIMPLE trial). BMJ Open 9:11, pages e029098.
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