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Clinical Features - Original Research

Physical frailty and cognitive impairment is associated with diabetes and adversely impact functional status and mortality

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Pages 561-567 | Received 05 Mar 2018, Accepted 19 Jun 2018, Published online: 26 Jul 2018

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Read on this site (7)

Yinhui Deng, Na Li, Yaru Wang, Chen Xiong & Xiaofang Zou. (2023) Risk Factors and Prediction Nomogram of Cognitive Frailty with Diabetes in the Elderly. Diabetes, Metabolic Syndrome and Obesity 16, pages 3175-3185.
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Ahmed H Abdelhafiz. (2023) Effects of glycemic control on frailty: a multidimensional perspective. Hospital Practice 51:3, pages 124-134.
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Ahmed H Abdelhafiz. (2023) Effects of hypoglycaemic therapy on frailty: a multi-dimensional perspective. Expert Review of Endocrinology & Metabolism 18:1, pages 53-65.
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Ahmet Cigiloglu, Eyyup Murat Efendioglu & Zeynel Abidin Ozturk. (2022) A retrospective study of diabetes treatment in older adults: what should we AIM for?. Postgraduate Medicine 134:7, pages 693-697.
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Xiao-Ming Zhang, Jing Jiao, Chen Zhu, Na Guo, Ying Liu, Dongmei Lv, Hui Wang, Jingfen Jin, Xianxiu Wen, Shengxiu Zhao, Xin-Juan Wu & Tao Xu. (2021) Cognitive Frailty and 30-Day Mortality in a National Cohort of Older Chinese Inpatients. Clinical Interventions in Aging 16, pages 389-401.
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Kwong Hsia Yap, Narelle Warren, Pascale Allotey & Daniel D. Reidpath. (2020) Chronic disease profiles of subjective memory complaints: a latent class analysis of older people in a rural Malaysian community. Aging & Mental Health 24:5, pages 709-716.
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Laure Sayyed Kassem & David C. Aron. (2020) The assessment and management of quality of life of older adults with diabetes mellitus. Expert Review of Endocrinology & Metabolism 15:2, pages 71-81.
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Articles from other publishers (46)

Takaharu Goto, Takahiro Kishimoto, Shinji Fujiwara, Yasuhiko Shirayama & Tetsuo Ichikawa. (2024) Social frailty as a predictor of all-cause mortality and functional disability: a systematic review and meta-analysis. Scientific Reports 14:1.
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Yi-Yin Hu & Ronnell D. Dela Rosa. (2023) Cognitive frailty in the elderly: a concept analysis. Frontiers of Nursing 10:4, pages 393-398.
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Taewha Lee, Jane Chung, Kijun Song & Yoonjung Ji. (2023) Prevalence and associated factors of cognitive frailty in community‐dwelling older adults: Results from the Korean longitudinal study of aging. International Journal of Older People Nursing 18:6.
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Yu-Nan Qin & Xiao-Pu Zheng. (2023) Association of frailty index with congestive heart failure, all-cause and cardiovascular mortality among individuals with type 2 diabetes: a study from National Health and Nutrition Examination Surveys (NHANES), 1999–2018. Diabetology & Metabolic Syndrome 15:1.
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Junjie Peng, Limei Ming, Jiaming Wu, Yunchuan Li, Shuhua Yang & Qin Liu. (2023) Prevalence and related factors of cognitive frailty in diabetic patients in China: a systematic review and meta-analysis. Frontiers in Public Health 11.
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Abrar-Ahmad Zulfiqar, Ibrahima Amadou Dembélé, Nouroudine Amadou & Emmanuel Andrès. (2023) Étude des liens entre diabète de type 2 et critères gériatriques. Soins Gérontologie 28:163, pages 43-45.
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Yu Zhang, Jing‐Jing Zhou, Xu‐Ming Zhang, Jing‐Ting Liu, Min‐Rui Li, Jia‐Yi Liang & Yu‐Lin Gao. (2023) Management of cognitive frailty: A network meta‐analysis of randomized controlled trials. International Journal of Geriatric Psychiatry 38:9.
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McKayla Massey, YunYing Zhong, Jacqueline B. LaManna & Boon Peng Ng. (2023) Food Insecurity Among Medicare Beneficiaries With Type 2 Diabetes: Implications for Diabetes Care and Education Specialists. The Science of Diabetes Self-Management and Care 49:4, pages 291-302.
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Shih-Tsung Huang, Liang-Kung Chen & Fei-Yuan Hsiao. (2023) Clinical impacts of frailty on 123,172 people with diabetes mellitus considering the age of onset and drugs of choice: a nationwide population-based 10-year trajectory analysis. Age and Ageing 52:7.
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Ahmed H. Abdelhafiz, Grace L. Keegan & Alan J. Sinclair. (2023) Metabolic Characteristics of Frail Older People with Diabetes Mellitus—A Systematic Search for Phenotypes. Metabolites 13:6, pages 705.
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Olufemi O Oyewole, Ayotunde O Ale, Michael O Ogunlana & Thavanesi Gurayah. (2023) Burden of disability in type 2 diabetes mellitus and the moderating effects of physical activity. World Journal of Clinical Cases 11:14, pages 3128-3139.
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Qiong Lyu, Chi‐Xun Guan, Ling‐Na Kong & Jia‐Lu Zhu. (2022) Prevalence and risk factors of cognitive frailty in community‐dwelling older adults with diabetes: A systematic review and meta‐analysis. Diabetic Medicine 40:1.
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Alan J. Sinclair & Ahmed H. Abdelhafiz. (2022) Multimorbidity, Frailty and Diabetes in Older People–Identifying Interrelationships and Outcomes. Journal of Personalized Medicine 12:11, pages 1911.
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Zhiqiang Li, Shengshu Wang, Shaohua Liu, Xinran Gong, Yanding Wang, Di Wu, Meitao Yang, Rongrong Li, Haowei Li, Xuehang Li, Shimin Chen, Ruizhong Jia, Jinpeng Guo, Jianhua Wang, Miao Liu, Yao He & Yong Wang. (2022) Synergistic impact of diabetes and cognitive impairment on all-cause and cause-specific mortality in Chinese older adults: A prospective population-based cohort study. Frontiers in Endocrinology 13.
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Phap Tran Ngoc Hoang, Aya Kadota, Yuichiro Yano, Akiko Harada, Takehito Hayakawa, Shohei Okamoto, Naoko Miyagawa, Keiko Kondo, Nagako Okukda, Yoshiuni Kita, Akira Okayama, Yukihiro Fujita, Hiroshi Maegawa, Katsuyuki Miura, Tomonori Okamura & Hirotsugu Ueshima. (2022) Effect of diabetes and prediabetes on the development of disability and mortality among middle‐aged Japanese adults: A 22‐year follow up of NIPPON DATA90 . Journal of Diabetes Investigation 13:11, pages 1897-1904.
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Yael Sela, Keren Grinberg, Tali Cukierman-Yaffe & Rachel Natovich. (2022) Relationship between cognitive function in individuals with diabetic foot ulcer and mortality. Diabetology & Metabolic Syndrome 14:1.
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Carla Ferreira do Nascimento, Alejandra Andrea Roman Lay, Yeda Aparecida Oliveira Duarte & Alexandre Dias Porto Chiavegatto Filho. (2022) Functional mobility and 10-year all-cause and cause-specific mortality in older people from São Paulo, Brazil. Brazilian Journal of Physical Therapy 26:4, pages 100431.
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Alan J. Sinclair, Daniel Pennells & Ahmed H. Abdelhafiz. (2022) Hypoglycaemic therapy in frail older people with type 2 diabetes mellitus—a choice determined by metabolic phenotype. Aging Clinical and Experimental Research 34:9, pages 1949-1967.
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Chia‐Ling Lin, Neng‐Chun Yu, Hsueh‐Ching Wu & Yuan‐Ching Liu. (2021) Risk factors associated with frailty in older adults with type 2 diabetes: A cross‐sectional study. Journal of Clinical Nursing 31:7-8, pages 967-974.
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A.H. Abdelhafiz & A.J. Sinclair. (2022) Metabolic phenotypes explain the relationship between dysglycaemia and frailty in older people with type 2 diabetes. Journal of Diabetes and its Complications 36:4, pages 108144.
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Iwona Bonikowska, Katarzyna Szwamel & Izabella Uchmanowicz. (2022) Adherence to Medication in Older Adults with Type 2 Diabetes Living in Lubuskie Voivodeship in Poland: Association with Frailty Syndrome. Journal of Clinical Medicine 11:6, pages 1707.
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Raffaele Antonelli Incalzi. (2021) Surgery in older patients with diabetes. Journal of Gerontology and Geriatrics 69:4, pages 292-295.
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Alexandra M Wennberg, Mozhu Ding, Marcus Ebeling, Niklas Hammar & Karin Modig. (2021) Blood-Based Biomarkers and Long-term Risk of Frailty—Experience From the Swedish AMORIS Cohort. The Journals of Gerontology: Series A 76:9, pages 1643-1652.
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Linglin Kong, Huimin Zhao, Junyao Fan, Quan Wang, Jie Li, Jinbing Bai & Jing Mao. (2021) Predictors of frailty among Chinese community-dwelling older adults with type 2 diabetes: a cross-sectional survey. BMJ Open 11:3, pages e041578.
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Fabio Castellana, Luisa Lampignano, Ilaria Bortone, Roberta Zupo, Madia Lozupone, Chiara Griseta, Antonio Daniele, Giovanni De Pergola, Gianluigi Giannelli, Rodolfo Sardone & Francesco Panza. (2021) Physical Frailty, Multimorbidity, and All-Cause Mortality in an Older Population From Southern Italy: Results from the Salus in Apulia Study. Journal of the American Medical Directors Association 22:3, pages 598-605.
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Anna Brzecka, Natalia Madetko, Vladimir N. Nikolenko, Ghulam M. Ashraf, Maria Ejma, Jerzy Leszek, Cyryl Daroszewski, Karolina Sarul, Liudmila M. Mikhaleva, Siva G. Somasundaram, Cecil E. Kirkland, Sergey O. Bachurin & Gjumrakch Aliev. (2020) Sleep Disturbances and Cognitive Impairment in the Course of Type 2 Diabetes-A Possible Link. Current Neuropharmacology 19:1, pages 78-91.
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Si-Min Yao, Pei-Pei Zheng, Yao-Dan Liang, Yu-Hao Wan, Ning Sun, Yao Luo, Jie-Fu Yang & Hua Wang. (2020) Predicting non-elective hospital readmission or death using a composite assessment of cognitive and physical frailty in elderly inpatients with cardiovascular disease. BMC Geriatrics 20:1.
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Peter Hanlon, Isabella Fauré, Neave Corcoran, Elaine Butterly, Jim Lewsey, David McAllister & Frances S Mair. (2020) Frailty measurement, prevalence, incidence, and clinical implications in people with diabetes: a systematic review and study-level meta-analysis. The Lancet Healthy Longevity 1:3, pages e106-e116.
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Yoshiaki Tamura, Takuya Omura, Kenji Toyoshima & Atsushi Araki. (2020) Nutrition Management in Older Adults with Diabetes: A Review on the Importance of Shifting Prevention Strategies from Metabolic Syndrome to Frailty. Nutrients 12:11, pages 3367.
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Peter Hanlon, Isabella Fauré, Neave Corcoran, Elaine Butterly, Jim Lewsey, David A McAllister & Frances S Mair. (2020) Identification and prevalence of frailty in diabetes mellitus and association with clinical outcomes: a systematic review protocol. BMJ Open 10:9, pages e037476.
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Shuangling Xiu, Zhijing Mu, Lei Zhao & Lina Sun. (2020) Low free triiodothyronine levels are associated with risk of frailty in older adults with type 2 diabetes mellitus. Experimental Gerontology 138, pages 111013.
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Alan J. Sinclair & Ahmed H. Abdelhafiz. (2020) Challenges and Strategies for Diabetes Management in Community-Living Older Adults. Diabetes Spectrum 33:3, pages 217-227.
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Javier Angulo, Mariam El Assar, Alejandro Álvarez-Bustos & Leocadio Rodríguez-Mañas. (2020) Physical activity and exercise: Strategies to manage frailty. Redox Biology 35, pages 101513.
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Edgardo Molina-Sotomayor, Wanesa Onetti-Onetti, Alfonso Castillo-Rodríguez & Jose Antonio González-Jurado. (2020) Changes in Cognitive Function and in the Levels of Glycosylated Haemoglobin (HbA1c) in Older Women with Type 2 Diabetes Mellitus Subjected to a Cardiorespiratory Exercise Programme. Sustainability 12:12, pages 5038.
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Satilmis Bilgin, Gulali Aktas, Ozge Kurtkulagi, Burcin M. Atak & Tuba T. Duman. (2020) Edmonton frail score is associated with diabetic control in elderly type 2 diabetic subjects. Journal of Diabetes & Metabolic Disorders 19:1, pages 511-514.
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Rodrigo Pérez-Rodríguez, Tania Guevara-Guevara, Pedro A. Moreno-Sánchez, Elena Villalba-Mora, Myriam Valdés-Aragonés, Myriam Oviedo-Briones, José A. Carnicero & Leocadio Rodríguez-Mañas. (2020) Monitoring and Intervention Technologies to Manage Diabetic Older Persons: The CAPACITY Case—A Pilot Study. Frontiers in Endocrinology 11.
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Javad Razjouyan, Bijan Najafi, Molly Horstman, Amir Sharafkhaneh, Mona Amirmazaheri, He Zhou, Mark E. Kunik & Aanand Naik. (2020) Toward Using Wearables to Remotely Monitor Cognitive Frailty in Community-Living Older Adults: An Observational Study. Sensors 20:8, pages 2218.
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A.H. Abdelhafiz, P.C. Davies & A.J. Sinclair. (2020) Triad of impairment in older people with diabetes-reciprocal relations and clinical implications. Diabetes Research and Clinical Practice 161, pages 108065.
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Nurul Fatin Malek Rivan, Suzana Shahar, Nor Fadilah Rajab, Devinder Kaur Ajit Singh, Normah Che Din, Hazlina Mahadzir, Noor Ibrahim Mohamed Sakian, Wan Syafira Ishak, Mohd Harimi Abd. Rahman, Zainora Mohammed & Yee Xing You. (2020) Incidence and Predictors of Cognitive Frailty Among Older Adults: A Community-based Longitudinal Study. International Journal of Environmental Research and Public Health 17:5, pages 1547.
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C.Y. Cheong, M.S.Z. Nyunt, Q. Gao, X. Gwee, R.W.M. Choo, K.B. Yap, S.L. Wee & Tze-Pin Ng. (2020) Risk Factors of Progression to Frailty: Findings from the Singapore Longitudinal Ageing Study. The Journal of nutrition, health and aging 24:1, pages 98-106.
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J. A. Vaccaro, T. Gaillard, F. G. Huffman & E. R. Vieira. (2019) Motivational Strategies to Prevent Frailty in Older Adults with Diabetes: A Focused Review. Journal of Aging Research 2019, pages 1-8.
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Vera E R Asscher, Felicia V Y Lee-Kong, Esther D Kort, Floor J van Deudekom, Simon P Mooijaart & P W Jeroen Maljaars. (2019) Systematic Review: Components of a Comprehensive Geriatric Assessment in Inflammatory Bowel Disease—A Potentially Promising but Often Neglected Risk Stratification. Journal of Crohn's and Colitis 13:11, pages 1418-1432.
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Anna Picca, Hélio José Coelho-Junior, Matteo Cesari, Federico Marini, Alfredo Miccheli, Jacopo Gervasoni, Maurizio Bossola, Francesco Landi, Roberto Bernabei, Emanuele Marzetti & Riccardo Calvani. (2019) The metabolomics side of frailty: Toward personalized medicine for the aged. Experimental Gerontology 126, pages 110692.
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A. H. Abdelhafiz & A. J. Sinclair. (2019) Cognitive Frailty in Older People with Type 2 Diabetes Mellitus: the Central Role of Hypoglycaemia and the Need for Prevention. Current Diabetes Reports 19:4.
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Kristin K. Clemens, Niamh O’Regan & Jinnie J. Rhee. (2019) Diabetes Management in Older Adults With Chronic Kidney Disease. Current Diabetes Reports 19:3.
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Mariam El Assar, Olga Laosa & Leocadio Rodríguez Mañas. (2019) Diabetes and frailty. Current Opinion in Clinical Nutrition & Metabolic Care 22:1, pages 52-57.
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