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Original Articles

Large Scale Preparation of Myelin Basic Protein from Central Nervous Tissue of Several Mammalian Species

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Pages 139-165 | Published online: 06 Dec 2006

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Galina V. Seledtsova, Irina P. Ivanova, Alexey A. Shishkov & Victor I. Seledtsov. (2016) Immune responses to polyclonal T-cell vaccination in patients with progressive multiple sclerosis. Journal of Immunotoxicology 13:6, pages 879-884.
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C. L. Yasuda, A. Al-sabbagh, E. C. Oliveira, B. M. Diaz-Bardales, C. A. A. Garcia & L. M-B Santos. (1999) Interferon β Modulates Experimental Autoimmune Encephalomyelitis by Altering the Pattern of Cytokine Secretion. Immunological Investigations 28:2-3, pages 115-126.
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K. Guo & H.H. Berlet. (1997) Isolation of Myelin Basic Protein from Whole Tissue Extracts by Selective pH-Dependent Solubilization. Preparative Biochemistry & Biotechnology 27:4, pages 289-304.
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Roland Martin, Henry F. McFarland & J. M. Boggs. (1995) Immunological Aspects of Experimental Allergic Encephalomyelitis and Multiple Sclerosis. Critical Reviews in Clinical Laboratory Sciences 32:2, pages 121-182.
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Cris S. Constantinescu, Elvira Ventura, Brendan Hilliard & Abdolmohamad Rostami. (1995) Effects of the Angiotensin Converting Enzyme Inhibitor Captopril on Experimental Autoimmune Encephalomyelitis. Immunopharmacology and Immunotoxicology 17:3, pages 471-491.
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Rhonda R. Voskuhl, Roland Martin, Cheryl Bergman, Mira Dalal, Nancy H. Ruddle & Henry F. Mcfarland. (1993) T Helper 1 (TH1) Functional Phenotype of Human Myelin Basic Protein-Specific T Lymphocytes. Autoimmunity 15:2, pages 137-143.
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Zhang Jingwu, Ying Chin, Paula Henderikx, Robert Medaer, C-H. Chou & Jef Cm. Raus. (1991) Antibodies to Myelin Basic Protein and Measles Virus in Multiple Sclerosis: Precursor Frequency Analysis of the Antibody Producing B Cells. Autoimmunity 11:1, pages 27-34.
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A. F. Walls, A. J. Suckling & M. G. Rumsby. (1989) The Origin and Specificity of Intrathecal Igg in Chronic Relapsing Experimental Allergic Encephalomyelitis. Autoimmunity 2:2, pages 123-132.
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Tadashi Hamada, Bernard F. Driscoll, Marian W. Kies & Ellsworth C. Alvord. (1989) LPS Augments Adoptive Transfer of Experimental Allergic Encephalomyelitis in the Lewis Rat. Autoimmunity 2:4, pages 275-284.
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Manjula K. Gupta. (1986) Myelin Basic Protein and Demyelinating Diseases. CRC Critical Reviews in Clinical Laboratory Sciences 24:4, pages 287-314.
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V. Wicher & R. Holub. (1982) Cellular Response to Basic Protein and T Suppressor Cells in Multiple Sclerosis. Immunological Communications 11:6, pages 495-507.
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O.M. Pitts, A.A. Barrows & E.D. Day. (1976) An Evaluation of a Procedure for the Isolation of Myelin Basic Protein (BP). Preparative Biochemistry 6:4, pages 239-264.
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Kalliopi Pitarokoili, Bjoern Ambrosius & Ralf Gold. (2018) Lewis Rat Model of Experimental Autoimmune Encephalomyelitis. Current Protocols in Neuroscience 81:1.
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W. Knoll, J. Peters, P. Kursula, Y. Gerelli & F. Natali. (2014) Influence of myelin proteins on the structure and dynamics of a model membrane with emphasis on the low temperature regime. The Journal of Chemical Physics 141:20.
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Marielle Thewissen, Veerle Somers, Niels Hellings, Judith Fraussen, Jan Damoiseaux & Piet Stinissen. (2007) CD4+CD28null T Cells in Autoimmune Disease: Pathogenic Features and Decreased Susceptibility to Immunoregulation. The Journal of Immunology 179:10, pages 6514-6523.
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Dannie E.M. Hallal-LongoSandra R. MirandolaElaine C. OliveiraAlessandro S. FariasFernanda G. PereiraIrene L. MetzeCarlos Otavio BrandãoHeloísa H. RuoccoBenito P. DamascenoLeonilda M.B. Santos. (2007) Diminished Myelin-Specific T Cell Activation Associated with Increase in CTLA4 and Fas Molecules in Multiple Sclerosis Patients Treated with IFN- β . Journal of Interferon & Cytokine Research 27:10, pages 865-874.
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Yue-Shi Mao, Chuan-Zhen Lu, Xin Wang & Bao-Guo Xiao. (2007) Induction of experimental autoimmune encephalomyelitis in Lewis rats by a viral peptide with limited homology to myelin basic protein. Experimental Neurology 206:2, pages 231-239.
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Guifang Cai & David A. Hafler. (2007) Multispecific responses by T cells expanded by endogenous self‐peptide/MHC complexes. European Journal of Immunology 37:3, pages 602-612.
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Wenjie Chen, Hong Li, Yi Jia, Meili Lv, Mingyuan Li, Ping Feng, Huaizhong Hu & Lin Zhang. (2007) In vivo administration of plasmid DNA encoding recombinant immunotoxin DT390-IP-10 attenuates experimental autoimmune encephalomyelitis. Journal of Autoimmunity 28:1, pages 30-40.
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Anne H. Cross, Jennifer L. Stark, Joanne Lauber, Michael J. Ramsbottom & Jeri-Anne Lyons. (2006) Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patients. Journal of Neuroimmunology 180:1-2, pages 63-70.
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Hiroshi Sakuma, Il‐Kwon Park, Kuniko Kohyama, Dongyun Feng & Yoh Matsumoto. (2006) Quantitation of myelin oligodendrocyte glycoprotein and myelin basic protein in the thymus and central nervous system and its relationship to the clinicopathologic features of autoimmune encephalomyelitis. Journal of Neuroscience Research 84:3, pages 606-613.
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S.L.G. Antunes, L.M. Chimelli, E.T. Rabello, V.C. Valentim, S. Corte-Real, E.N. Sarno & M.R. Jardim. (2006) An immunohistochemical, clinical and electroneuromyographic correlative study of the neural markers in the neuritic form of leprosy. Brazilian Journal of Medical and Biological Research 39:8, pages 1071-1081.
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Fabrizio G. Mastronardi & Mario A. Moscarello. (2005) Molecules affecting myelin stability: A novel hypothesis regarding the pathogenesis of multiple sclerosis. Journal of Neuroscience Research 80:3, pages 301-308.
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Caroline D. Pointer-Keenan, Dong-Kuk Lee, Kevin Hallok, Anmin Tan, Robert Zand & Ayyalusamy Ramamoorthy. (2004) Investigation of the interaction of myelin basic protein with phospholipid bilayers using solid-state NMR spectroscopy. Chemistry and Physics of Lipids 132:1, pages 47-54.
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Hans‐Christian von Büdingen, Stephen L. Hauser, Jean‐Christophe Ouallet, Naoyuki Tanuma, Til Menge & Claude P. Genain. (2004) Frontline: Epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune demyelination. European Journal of Immunology 34:8, pages 2072-2083.
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G Cavaletti, E Cavalletti, L Crippa, E Di Luccio, N Oggioni, B Mazzanti, T Biagioli, F Sala, V Sala, M Frigo, S Rota, E Tagliabue, L Stanzani, S Galbiati, R Rigolio, C Zoia, G Tredici, P Perseghin, M Dassi, P Riccio & F Lolli. (2004) Pixantrone (BBR2778) reduces the severity of experimental allergic encephalomyelitis. Journal of Neuroimmunology 151:1-2, pages 55-65.
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Judith M. Greer, Peter A. Csurhes, Michael P. Pender & Pamela A. McCombe. (2004) Effect of gender on T-cell proliferative responses to myelin proteolipid protein antigens in patients with multiple sclerosis and controls. Journal of Autoimmunity 22:4, pages 345-352.
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Marco E.F Melo, David B Stevens, Eli E Sercarz & Claudia Raja Gabaglia. (2004) Nasal instillation of gpMBP can exacerbate murine EAE: effect of mucosal priming is an age-dependent phenomenon. Journal of Autoimmunity 22:1, pages 13-20.
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Karen M. Palaszynski, Kyi Kyi Loo, Judith F. Ashouri, Hong-biao Liu & Rhonda R. Voskuhl. (2004) Androgens are protective in experimental autoimmune encephalomyelitis: implications for multiple sclerosis. Journal of Neuroimmunology 146:1-2, pages 144-152.
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Catharina B.M. Maassen, Jon D. Laman, Conny van Holten-Neelen, Linsy Hoogteijling, Lizet Groenewegen, Lizette Visser, Marc M. Schellekens, Wim J.A. Boersma & Eric Claassen. (2003) Reduced experimental autoimmune encephalomyelitis after intranasal and oral administration of recombinant lactobacilli expressing myelin antigens. Vaccine 21:32, pages 4685-4693.
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Jacqueline Harness, Alice Cavanagh, Halle Morton & Pamela McCombe. (2003) A protective effect of early pregnancy factor on experimental autoimmune encephalomyelitis induced in Lewis rats by inoculation with myelin basic protein. Journal of the Neurological Sciences 216:1, pages 33-41.
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Stavrosia Athanasas-Platsis, Bing Zhang, Narelle C. Hillyard, Alice C. Cavanagh, Peter A. Csurhes, Halle Morton & Pamela A. McCombe. (2003) Early pregnancy factor suppresses the infiltration of lymphocytes and macrophages in the spinal cord of rats during experimental autoimmune encephalomyelitis but has no effect on apoptosis. Journal of the Neurological Sciences 214:1-2, pages 27-36.
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G. Sireci, F. Dieli, N. Caccamo, A. Barera, P. Carta, C. Di Sano, S. Meraviglia, C. T. Bonanno & A. Salerno. (2003) A Human Leucocyte Antigen‐DR1 Transgene Confers Susceptibility to Experimental Allergic Encephalomyelitis Elicited by an Epitope of Myelin Basic Protein. Scandinavian Journal of Immunology 58:2, pages 188-194.
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F. Natali, A. Relini, A. Gliozzi, R. Rolandi, P. Cavatorta, A. Deriu, A. Fasano & P. Riccio. (2003) Protein–membrane interaction: effect of myelin basic protein on the dynamics of oriented lipids. Chemical Physics 292:2-3, pages 455-464.
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Akira Miyakoshi, Won Kee Yoon, Youngheun Jee & Yoh Matsumoto. (2003) Characterization of the Antigen Specificity and TCR Repertoire, and TCR-Based DNA Vaccine Therapy in Myelin Basic Protein-Induced Autoimmune Encephalomyelitis in DA Rats. The Journal of Immunology 170:12, pages 6371-6378.
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Jan Sedzik, Giulia Carlone, Anna Fasano, Grazia Maria Liuzzi & Paolo Riccio. (2003) Crystals of P2 myelin protein in lipid-bound form. Journal of Structural Biology 142:2, pages 292-300.
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Kevin C O'Connor, Tanuja Chitnis, Diane E Griffin, Sucheep Piyasirisilp, Amit Bar-Or, Samia Khoury, Kai W Wucherpfennig & David A Hafler. (2003) Myelin basic protein-reactive autoantibodies in the serum and cerebrospinal fluid of multiple sclerosis patients are characterized by low-affinity interactions. Journal of Neuroimmunology 136:1-2, pages 140-148.
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TOSHIE YONEHARA, YOKO YAMADA, HARUHIKO KANASAKI, HIDEYUKI YAMAMOTO, KOHJI FUKUNAGA, KOHJI MIYAZAKI & EISHICHI MIYAMOTO. (2003) Characterization of .ALPHA.T3-1 Cells Stably Transfected with Luteininzing Hormone .BETA.-Subunit Complementary Deoxyribonucleic Acid. Endocrine Journal 50:3, pages 341-354.
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P.A Muraro, M Kalbus, G Afshar, H.F McFarland & R Martin. (2002) T cell response to 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) in multiple sclerosis patients. Journal of Neuroimmunology 130:1-2, pages 233-242.
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H.J. Kim, J.P. Antel, P. Duquette, D.G. Alleva, P.J. Conlon & A. Bar-Or. (2002) Persistence of Immune Responses to Altered and Native Myelin Antigens in Patients with Multiple Sclerosis Treated with Altered Peptide Ligand. Clinical Immunology 104:2, pages 105-114.
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G MAZZA, M PONSFORD, P LOWREY, M J CAMPBELL, J ZAJICEK & D C WRAITH. (2002) Diversity and dynamics of the T-cell response to MBP in DR2 + ve individuals . Clinical and Experimental Immunology 128:3, pages 538-547.
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Caishu Deng, Alfredo Minguela, Rehana Z. Hussain, Amy E. Lovett-Racke, Caius Radu, E. Sally Ward & Michael K. Racke. (2002) Expression of the Tyrosine Phosphatase Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 Determines T Cell Activation Threshold and Severity of Experimental Autoimmune Encephalomyelitis. The Journal of Immunology 168:9, pages 4511-4518.
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Ruth Maron, Anthony J. Slavin, Ethan Hoffmann, Yoshinori Komagata & Howard L. Weiner. (2002) Oral tolerance to copolymer 1 in myelin basic protein (MBP) TCR transgenic mice: cross-reactivity with MBP-specific TCR and differential induction of anti-inflammatory cytokines. International Immunology 14:2, pages 131-138.
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M Ponsford, G Mazza, J Coad, M J Campbell, J Zajicek & D C Wraith. (2001) Differential responses of CD45+ve T-cell subsets to MBP in multiple sclerosis. Clinical and Experimental Immunology 124:2, pages 315-322.
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E Traggiai, T Biagioli, E Rosati, C Ballerini, B Mazzanti, A Ben Nun, L Massacesi & M Vergelli. (2001) IL-7-enhanced T-cell response to myelin proteins in multiple sclerosis. Journal of Neuroimmunology 121:1-2, pages 111-119.
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M. Vergelli, B. Mazzanti, E. Traggiai, T. Biagioli, C. Ballerini, A. Parigi, A. Konse, G. Pellicanò & L. Massacesi. (2001) Short‐term evolution of autoreactive T cell repertoire in multiple sclerosis. Journal of Neuroscience Research 66:3, pages 517-524.
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Heinrich Haas, Gianrico Lamura & Alessandra Gliozzi. (2001) Improvement of the quality of self assembled bilayer lipid membranes by using a negative potential. Bioelectrochemistry 54:1, pages 1-10.
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F Natali, A Gliozzi, R Rolandi, P Cavatorta, A Deriu, A Fasano & P Riccio. (2001) Myelin basic protein reduces molecular motions in DMPA, an elastic neutron scattering study. Physica B: Condensed Matter 301:1-2, pages 145-149.
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Hai-Tao Yang, Kristin Bergsteinsdottir, Patrik Wernhoff, Christopher Linington, Ulf Pettersson & Rikard Holmdahl. (2001) Genetic linkage analysis of the antibody responses to myelin basic protein and myelin oligodendrocyte glycoprotein in rats immunized with rat spinal cord homogenate. Journal of Neuroimmunology 117:1-2, pages 21-29.
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Judith M. Greer, Bérangère Denis, Raymond A. Sobel & Elisabeth Trifilieff. (2001) Thiopalmitoylation of Myelin Proteolipid Protein Epitopes Enhances Immunogenicity and Encephalitogenicity. The Journal of Immunology 166:11, pages 6907-6913.
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Anthony J. Slavin, Ruth Maron & Howard L. Weiner. (2001) Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes. International Immunology 13:6, pages 825-833.
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Jackie Harness, Michael P Pender & Pamela A McCombe. (2001) Cyclosporin A treatment modulates cytokine mRNA expression by inflammatory cells extracted from the spinal cord of rats with experimental autoimmune encephalomyelitis induced by inoculation with myelin basic protein. Journal of the Neurological Sciences 187:1-2, pages 7-16.
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Abbie L. Meyer, Jacqueline Benson, Fei Song, Najma Javed, Ingrid E. Gienapp, Joan Goverman, Thea A. Brabb, Leroy Hood & Caroline C. Whitacre. (2001) Rapid Depletion of Peripheral Antigen-Specific T Cells in TCR-Transgenic Mice After Oral Administration of Myelin Basic Protein. The Journal of Immunology 166:9, pages 5773-5781.
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Hong-biao Liu, Allan J. MacKenzie-Graham, Karen Palaszynski, Stephanie Liva & Rhonda R. Voskuhl. (2001) ?Classic? myelin basic proteins are expressed in lymphoid tissue macrophages. Journal of Neuroimmunology 116:1, pages 83-93.
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Hong-biao Liu, Allan J MacKenzie-Graham, Sookhyun Kim & Rhonda R Voskuhl. (2001) Mice resistant to experimental autoimmune encephalomyelitis have increased thymic expression of myelin basic protein and increased MBP specific T cell tolerance. Journal of Neuroimmunology 115:1-2, pages 118-126.
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Andreas Steinbrecher, Dirk Reinhold, Laura Quigley, Ameer Gado, Nancy Tresser, Leonid Izikson, Ilona Born, Jürgen Faust, Klaus Neubert, Roland Martin, Siegfried Ansorge & Stefan Brocke. (2001) Targeting Dipeptidyl Peptidase IV (CD26) Suppresses Autoimmune Encephalomyelitis and Up-Regulates TGF-β1 Secretion In Vivo. The Journal of Immunology 166:3, pages 2041-2048.
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D Karussis, O Abramsky, N Grigoriadis, J Chapman, R Mizrachi-Koll, H Niv & Y Kloog. (2001) The Ras-pathway inhibitor, S-trans-trans-farnesylthiosalicylic acid, suppresses experimental allergic encephalomyelitis. Journal of Neuroimmunology 120:1-2, pages 1-9.
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F.L. Gordon, K.B. Nguyen, C.A. White & M.P. Pender. (2001) Rapid entry and downregulation of T cells in the central nervous system during the reinduction of experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 112:1-2, pages 15-27.
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Rhonda B. Kean, Sergei V. Spitsin, Tatiana Mikheeva, Gwen S. Scott & D. Craig Hooper. (2000) The Peroxynitrite Scavenger Uric Acid Prevents Inflammatory Cell Invasion into the Central Nervous System in Experimental Allergic Encephalomyelitis through Maintenance of Blood-Central Nervous System Barrier Integrity. The Journal of Immunology 165:11, pages 6511-6518.
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Maria V. Tejada-Simon, Ying C. Q. Zang, Deye Yang, Jian Hong, Sufang Li, Rana A. K. Singh, Ella Van den Berg-Loonen, James M. Killian, Victor M. Rivera & Jingwu Z. Zhang. (2000) Aberrant T cell responses to myelin antigens during clinical exacerbation in patients with multiple sclerosis. International Immunology 12:12, pages 1641-1650.
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N Lanteri, R Rolandi, P Cavatorta, E Polverini, P Riccio & A Gliozzi. (2000) Myelin basic protein–lipid complex: an atomic force microscopy study. Colloids and Surfaces A: Physicochemical and Engineering Aspects 175:1-2, pages 3-9.
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Bing Zhang, Jackie Harness, Maria J Somodevilla-Torres, Narelle C Hillyard, Arne W Mould, Dianne Alewood, Stephen G Love, Paul F Alewood, Judith M Greer, Alice C Cavanagh, Pamela A McCombe & Halle Morton. (2000) Early pregnancy factor suppresses experimental autoimmune encephalomyelitis induced in Lewis rats with myelin basic protein and in SJL/J mice with myelin proteolipid protein peptide 139-151. Journal of the Neurological Sciences 182:1, pages 5-15.
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Michael P. Pender, Peter A. Csurhes, Judith M. Greer, Paul D. Mowat, Robert D. Henderson, Kaye D. Cameron, David M. Purdie, Pamela A. McCombe & Michael F. Good. (2000) Surges of Increased T Cell Reactivity to an Encephalitogenic Region of Myelin Proteolipid Protein Occur More Often in Patients with Multiple Sclerosis Than in Healthy Subjects. The Journal of Immunology 165:9, pages 5322-5331.
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