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Research Article

Comparison of iohexol and lactulose-mannitol tests as markers of disease activity in patients with inflammatory bowel disease

Pages 695-701 | Published online: 08 Jul 2009

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Lotta Luiskari, Hanna Launonen, Jere Lindén, Markku Lehto, Heikki Vapaatalo, Hanne Salmenkari & Riitta Korpela. (2023) Ketogenic Diet High in Saturated Fat Promotes Colonic Claudin Expression without Changes in Intestinal Permeability to Iohexol in Healthy Mice. Nutrients 16:1, pages 18.
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Melissa McGilloway, Shannon Manley, Alyssa Aho, Keisha N. Heeringa, Yanping Lou, Eli James Squires & Wendy Pearson. (2022) The combination of trailer transport and exercise increases gastrointestinal permeability and markers of systemic inflammation in horses. Equine Veterinary Journal 55:5, pages 853-861.
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Katrien Rysman, Venessa Eeckhaut, Siska Croubels, Brecht Maertens & Filip Van Immerseel. (2023) Iohexol is an intestinal permeability marker in broilers under coccidiosis challenge. Poultry Science 102:6, pages 102690.
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Jekaterina Rodina & Aleksejs Derovs. (2022) Establishing the cut-offs of leaky gut syndrome diagnostic: where are we now?. Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 76:5-6, pages 569-577.
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Luiz Augusto Cardoso LACOMBE, Camila MATIOLLO, Julia Salvan da ROSA, Mariano FELISBERTO, Eduardo Monguilhott DALMARCO & Leonardo de Lucca SCHIAVON. (2022) FACTORS ASSOCIATED WITH CIRCULATING ZONULIN IN INFLAMMATORY BOWEL DISEASE. Arquivos de Gastroenterologia 59:2, pages 238-243.
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Lauren W. Kaminsky, Rana Al-Sadi & Thomas Y. Ma. (2021) IL-1β and the Intestinal Epithelial Tight Junction Barrier. Frontiers in Immunology 12.
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Victoria Ortín-Piqueras, Tobias L Freitag, Leif C Andersson, Sanna H Lehtonen, Seppo K Meri, Thomas Spillmann & Rafael Frias. (2021) Urinary Excretion of Iohexol as a Permeability Marker in a Mouse Model of Intestinal Inflammation: Time Course, Performance and Welfare Considerations. Animals 11:1, pages 79.
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Sarah Chantler, Alex Griffiths, Jamie Matu, Glen Davison, Ben Jones & Kevin Deighton. (2020) The Effects of Exercise on Indirect Markers of Gut Damage and Permeability: A Systematic Review and Meta-analysis. Sports Medicine 51:1, pages 113-124.
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Elisa Karhu, Richard A. Forsgård, Lauri Alanko, Henrik Alfthan, Pirkko Pussinen, Esa Hämäläinen & Riitta Korpela. (2017) Exercise and gastrointestinal symptoms: running-induced changes in intestinal permeability and markers of gastrointestinal function in asymptomatic and symptomatic runners. European Journal of Applied Physiology 117:12, pages 2519-2526.
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Richard A. Forsgård, Riitta Korpela, Reetta Holma, Jere Lindén, Rafael Frias, Thomas Spillmann & Pia Österlund. (2016) Intestinal permeability to iohexol as an in vivo marker of chemotherapy-induced gastrointestinal toxicity in Sprague–Dawley rats. Cancer Chemotherapy and Pharmacology 78:4, pages 863-874.
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Lirui Wang, Cristina Llorente, Phillipp Hartmann, An-Ming Yang, Peng Chen & Bernd Schnabl. (2015) Methods to determine intestinal permeability and bacterial translocation during liver disease. Journal of Immunological Methods 421, pages 44-53.
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Ivana R. Sequeira, Roger G. Lentle, Marlena C. Kruger & Roger D. Hurst. (2014) Standardising the Lactulose Mannitol Test of Gut Permeability to Minimise Error and Promote Comparability. PLoS ONE 9:6, pages e99256.
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Neil Dalton, Susie Chandler, Charles Turner, Tony Charman, Andrew Pickles, Tom Loucas, Emily Simonoff, Peter Sullivan & Gillian Baird. (2013) Gut Permeability in Autism Spectrum Disorders. Autism Research 7:3, pages 305-313.
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Rafael Frias, Katrin Strube, Waldemar Ternes, M. Carmen Collado, Thomas Spillmann, Satu Sankari & Elias Westermarck. (2012) Comparison of 51Chromium-labeled ethylenediamine tetra-acetic acid and iohexol as blood markers for intestinal permeability testing in Beagle dogs. The Veterinary Journal 192:1, pages 123-125.
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Vanya A Gerova, Simeon G Stoynov, Dimitar S Katsarov & Dobrin A Svinarov. (2011) Increased intestinal permeability in inflammatory bowel diseases assessed by iohexol test. World Journal of Gastroenterology 17:17, pages 2211-2215.
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Merja Pöytäkangas, Elise Saario-Paunio, Tiina Putkonen, Ilkka Saastamoinen, Rafael Frias, Thomas Spillmann & Hannu Saloniemi. (2010) Rapid LC-UV Analysis of Iohexol in Canine Plasma for Glomerular Filtration Rate Determination. Chromatographia 71:3-4, pages 211-216.
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Stefanie Klenner, Manfred Coenen, Klaus Failing, Marion Hewicker‐Trautwein, Waldemar Ternes, Jutta Verspohl & Thomas Spillmann. (2009) Estimation of intestinal permeability in healthy dogs using the contrast medium iohexol. Veterinary Clinical Pathology 38:3, pages 353-360.
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S. Klenner, C. Bergmann, K. Strube, W. Ternes & T. Spillmann. (2007) SPE for Endo- and Exo-Iohexol Analysis with HPLC in Canine Serum and Rat Urine. Chromatographia 65:11-12, pages 733-736.
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Saku KOBAYASHI, Koichi OHNO, Koji UETSUKA, Ko NAKASHIMA, Asuka SETOGUCHI, Yasuhito FUJINO & Hajime TSUJIMOTO. (2007) Measurement of Intestinal Mucosal Permeability in Dogs with Lymphocytic-Plasmacytic Enteritis. Journal of Veterinary Medical Science 69:7, pages 745-749.
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Rita Paroni, Isabella Fermo, Laura Molteni, Laura Folini, Matteo Rocco Pastore, Andrea Mosca & Emanuele Bosi. (2006) Lactulose and mannitol intestinal permeability detected by capillary electrophoresis. Journal of Chromatography B 834:1-2, pages 183-187.
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Samir Giuseppe Sukkar, Emanuela Schenone, Luca Foppiani & Maria Teresa Nobile. (2018) Experimental Assessment of Chemotherapy-induced Early Intestinal Damage in Colon Cancer the Lactulose-mannitol Permeability Test. Tumori Journal 90:5, pages 461-463.
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Marieluise Harrer, Walter Reinisch, Clemens Dejaco, Verena Kratzer, Maria Gmeiner, Wolfgang Miehsler, Gary L Norman, Alfred Gangl & Harald Vogelsang. (2003) Do high serum levels of anti-Saccharomyces cerevisiae antibodies result from a leakiness of the gut barrier in Crohn's disease?. European Journal of Gastroenterology & Hepatology 15:12, pages 1281-1285.
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Frank A. Wollheim. (2001) Enteropathic arthritis: how do the joints talk with the gut?. Current Opinion in Rheumatology 13:4, pages 305-309.
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