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Research Article

Novel serum inflammatory markers in acute appendicitis

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Pages 579-584 | Published online: 08 Jul 2009

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Sandra Lorena de Oliveira Machado, Margarete Dulce Bagatini, Pauline da Costa, Jucimara Baldissarelli, Karine Paula Reichert, Lizielle Souza de Oliveira, Jéssica Gonçalves Lemos, Thiago Duarte, Maria Rosa Chitolina Schetinger & Vera Maria Morsch. (2016) Evaluation of mediators of oxidative stress and inflammation in patients with acute appendicitis. Biomarkers 21:6, pages 530-537.
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M. Groselj‐Grenc, S. Repše, Z. Dolenc‐Stražar, S. Hojker & M. Derganc. (2007) Interleukin‐6 and lipopolysaccharide‐binding protein in acute appendicitis in children. Scandinavian Journal of Clinical and Laboratory Investigation 67:2, pages 197-206.
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Osman Yildirim, Cem Solak, Belma Koçer, Bülent Ünal, Melih Karabeyoğlu, Betül Bozkurt, Sabahat Aksaray & Ömer Cengiz. (2006) The Role of Serum Inflammatory Markers in Acute Appendicitis and Their Success in Preventing Negative Laparotomy. Journal of Investigative Surgery 19:6, pages 345-352.
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Z. Türkyilmaz, K. Sönmez, R. Karabulut, Ş. Elbeğ, S. Moralioğlu, A. Demirtola, B. Demiroğullari, İ. O. Özen, A. C. Başaklar & N. Kale. (2006) Sequential cytokine levels in the diagnosis of appendicitis. Scandinavian Journal of Clinical and Laboratory Investigation 66:8, pages 723-732.
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Articles from other publishers (48)

Binyamin Sikander, Jacob Rosenberg & Siv Fonnes. (2023) Individual biomarkers in the blood are not yet applicable in diagnosing complicated appendicitis: A scoping review. The American Journal of Emergency Medicine 67, pages 100-107.
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春雪 付. (2023) Research Status and Progress of the Diagnostic Value of Multiple Experimental Indexes in Different Degrees of Acute Appendicitis. Advances in Clinical Medicine 13:02, pages 1968-1973.
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Gaurav KhanageDr.Dr., Juthikaa DeherkarDr.Dr. & Pravin BorkarDr.Dr.. (2022) EVALUATION OF CRP (C-REACTIVE PROTEIN) AND PROCALCITONIN AS DIAGNOSTIC MARKERS IN ACUTE APPENDICITIS. GLOBAL JOURNAL FOR RESEARCH ANALYSIS, pages 26-29.
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Sefa Sag, Levent Elemen, Kaan Masrabaci, Selenay Furat Recber, Yagmur Sonmez, Seval Aydin, Karolin Yanar, Esmanur Seker & Yusufhan Yazir. (2022) Potential therapeutic effects of ethyl pyruvate in an experimental rat appendicitis model. Journal of Pediatric Surgery 57:10, pages 457-462.
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Javier Arredondo Montero, Carlos Bardají Pascual, Mónica Bronte Anaut, Natalia López-Andrés, Giuseppa Antona & Nerea Martín-Calvo. (2022) Diagnostic performance of serum interleukin-6 in pediatric acute appendicitis: a systematic review. World Journal of Pediatrics 18:2, pages 91-99.
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Ąžuolas Algimantas Kaminskas, Raminta Lukšaitė-Lukštė, Eugenijus Jasiūnas, Artūras Samuilis, Vytautas Augustinavičius, Marius Kryžauskas, Kęstutis Strupas & Tomas Poškus. (2021) The Dynamics of Inflammatory Markers in Patients with Suspected Acute Appendicitis. Medicina 57:12, pages 1384.
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Shahab Hajibandeh, Shahin Hajibandeh, Morwena J Marshall, Neil J Smart, Paul Graham Winyard, Chris Hyde, Andrew M Shaw & Ian R Daniels. (2021) Biomarkers for diagnosis of acute appendicitis in adults. Cochrane Database of Systematic Reviews 2021:10.
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Sarah VL Hodge, Beata Mickiewicz, Matthew Lau, Craig N Jenne & Graham C Thompson. (2021) Novel molecular biomarkers and diagnosis of acute appendicitis in children. Biomarkers in Medicine 15:12, pages 1055-1065.
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Ahmet ERTÜRK, Can ÖZTORUN, Süleyman Arif BOSTANCI, Gökhan DEMİRTAŞ, Rabia DEMİR, Doğuş GÜNEY, Emine YURT, Özcan EREL, Cüneyt KARAGÖL, Müjdem AZILI & Emrah ŞENEL. (2021) The role of thiol-disulfide and ischemia-modified albumin levels in the diagnosis of childhood appendicitis. Anatolian Current Medical Journal 3:3, pages 214-219.
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Natalia Gryzunova, Igor Keri & Olga Romanchenko. (2021) Financial engineering of business processes and investment of industrial companies in the innovation system of megacity. SHS Web of Conferences 92, pages 04009.
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Mustafa Onur Oztan, Aysegul Aksoy Gokmen, Fatma Demet Arslan, Ebru Cakir, Ali Sayan, Elif Abay, Selçuk Kaya & Gokhan Koyluoglu. (2020) Diagnostic Value of Serum Urokinase-Type Plasminogen Activator Receptor in Children With Acute Appendicitis. Pediatric Emergency Care 36:7, pages 332-337.
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Sabri DEMİR, Yasemin DERE GÜNAL, İsmail ÖZMEN, Nermin DİNDAR BADEM, Salim NEŞELİOĞLU & Özcan EREL. (2020) Tiyol / Disülfit dengesinin değerlendirilmesi çocuklarda apandisitin ayırıcı tanısında yardımcı olabilir mi?. Turkish Journal of Pediatric Disease, pages 1-8.
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FawazM Aldhafiri, FahadM Aldhafiri, Mubarak Alshahrani, AdelD Almaymuni, MohammedRidha Algethami, AshrafA Maghrabi, HishamA Rizk & WisamH Jamal. (2020) Correlation of serum C-reactive protein, white blood count, and neutrophil percentage with histopathological findings in acute appendicitis. Saudi Surgical Journal 8:4, pages 167.
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Nikola Stankovic, Maja Surbatovic, Ivan Stanojevic, Radoje Simić, Slavisa Djuricic, Maja Milickovic, Blagoje Grujic, Djordje Savic, Vesna Milojkovic Marinovic, Miona Stankovic & Danilo Vojvodic. (2019) Possible cytokine biomarkers in pediatric acute appendicitis. Italian Journal of Pediatrics 45:1.
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S. Ali Naqvi, Graham C. Thompson, Ari R. Joffe, Jaime Blackwood, Dori-Ann Martin, Mary Brindle, Herman W. Barkema & Craig N. Jenne. (2019) Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators. Mediators of Inflammation 2019, pages 1-13.
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Ekaterina Orlova, Andrew Yeh, Min Shi, Brian Firek, Sarangarajan Ranganathan, David C. Whitcomb, David N. Finegold, Robert E. Ferrell, M. Michael Barmada, Mary L. Marazita, David A. Hinds, John R. Shaffer & Michael J. Morowitz. (2018) Genetic association and differential expression of PITX2 with acute appendicitis. Human Genetics 138:1, pages 37-47.
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Mohamed Amine Msolli, Kaouther Beltaief, Wahid Bouida, Nahla Jerbi, Mohamed Habib Grissa, Hamdi Boubaker, Riadh Boukef & Semir Nouira. (2018) Value of early change of serum C reactive protein combined to modified Alvarado score in the diagnosis of acute appendicitis. BMC Emergency Medicine 18:1.
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Nusrat S. Shommu, Craig N. Jenne, Jaime Blackwood, Ari R. Joffe, Dori-Ann Martin, Graham C. Thompson & Hans J. Vogel. (2018) Metabolomic and inflammatory mediator based biomarker profiling as a potential novel method to aid pediatric appendicitis identification. PLOS ONE 13:3, pages e0193563.
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Nusrat S. Shommu, Craig N. Jenne, Jaime Blackwood, Dori-Ann Martin, Ari R. Joffe, Robin Eccles, Mary Brindle, Ijab Khanafer, Hans J. Vogel & Graham C. Thompson. (2018) The Use of Metabolomics and Inflammatory Mediator Profiling Provides a Novel Approach to Identifying Pediatric Appendicitis in the Emergency Department. Scientific Reports 8:1.
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S.A. Kabir, S.I. Kabir, R. Sun, Sadaf Jafferbhoy & Ahmed Karim. (2017) How to diagnose an acutely inflamed appendix; a systematic review of the latest evidence. International Journal of Surgery 40, pages 155-162.
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Amish Acharya, Sheraz R. Markar, Melody Ni & George B. Hanna. (2016) Biomarkers of acute appendicitis: systematic review and cost–benefit trade-off analysis. Surgical Endoscopy 31:3, pages 1022-1031.
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Concepci?n M?guez, Cristina Tomatis Souverbielle, Ana Haro, Gloria Guerrero, Laura P?rez-Egido, Mercedes Garc?a-Gamiz & Rafael Mara?on. (2016) Evaluation of proadrenomedullin as a diagnostic or prognostic biomarker of acute appendicitis in children. The American Journal of Emergency Medicine 34:12, pages 2298-2305.
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Elina Lietzén, Imre Ilves, Paulina Salminen, Hannu Paajanen, Tero Rautio, Pia Nordström, Markku Aarnio, Tuomo Rantanen, Tommi Kauko, Airi Jartti, Juhani Sand, Jukka-Pekka Mecklin & Juha M. Grönroos. (2016) Clinical and laboratory findings in the diagnosis of right lower quadrant abdominal pain: outcome analysis of the APPAC trial. Clinical Chemistry and Laboratory Medicine (CCLM) 54:10, pages 1691-1697.
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Elina Lietz?n, Jari M?llinen, Juha M. Gr?nroos, Tero Rautio, Hannu Paajanen, Pia Nordstr?m, Markku Aarnio, Tuomo Rantanen, Juhani Sand, Jukka-Pekka Mecklin, Airi Jartti, Johanna Virtanen, Pasi Ohtonen & Paulina Salminen. (2016) Is preoperative distinction between complicated and uncomplicated acute appendicitis feasible without imaging?. Surgery 160:3, pages 789-795.
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Morwena Jane Marshall, Neil J Smart, Chris Hyde, Paul Graham Winyard, Andrew M Shaw & Ian R Daniels. (2015) Biomarkers for diagnosis of acute appendicitis in adults. Cochrane Database of Systematic Reviews.
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Manne Andersson, Marie Rubér, Christina Ekerfelt, Hanna Björnsson Hallgren, Gunnar Olaison & Roland E. Andersson. (2014) Can New Inflammatory Markers Improve the Diagnosis of Acute Appendicitis?. World Journal of Surgery 38:11, pages 2777-2783.
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Efstratios Saliakellis, Osvaldo Borrelli & Nikhil Thapar. (2013) Paediatric GI emergencies. Best Practice & Research Clinical Gastroenterology 27:5, pages 799-817.
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Zuhoor K Al-gaithy. (2012) Clinical value of total white blood cells and neutrophil counts in patients with suspected appendicitis: retrospective study. World Journal of Emergency Surgery 7:1, pages 32.
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Angela M. Mills, David S. Huckins, Heemun Kwok, Brigitte M. Baumann, Richard M. Ruddy, Richard E. Rothman, Jon W. Schrock, Frank Lovecchio, William I. Krief, Aaron Hexdall, Robert Caspari, Beth Cohen & Roger J. Lewis. (2012) Diagnostic Characteristics of S100A8/A9 in a Multicenter Study of Patients With Acute Right Lower Quadrant Abdominal Pain. Academic Emergency Medicine 19:1, pages 48-55.
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David J. Humes & John Simpson. 2012. Imaging of Acute Appendicitis in Adults and Children. Imaging of Acute Appendicitis in Adults and Children 13 21 .
Pinar Unverir & Ozgur Karcioglu. (2011) A Review of the Predictive Role of Plasma D-Lactate Level in Acute Appendicitis: A Myth or Truth?. ISRN Toxicology 2011, pages 1-6.
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Jianxin Li, Yan Liu, Weihua Yin, Chuanzhou Zhang, Jinhe Huang, Chaoyu Liao, Liping Nie, Yu Zhou & Ping Xiao. (2011) Alterations of the preoperative coagulation profile in patients with acute appendicitis. Clinical Chemistry and Laboratory Medicine (CCLM) 49:8, pages 1333-1339.
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Anupam B. Kharbanda, Yohaimi Cosme, Khin Liu, Steven L. Spitalnik & Peter S. Dayan. (2011) Discriminative Accuracy of Novel and Traditional Biomarkers in Children With Suspected Appendicitis Adjusted for Duration of Abdominal Pain. Academic Emergency Medicine 18:6, pages 567-574.
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Lauren Allister, Richard Bachur, Jonathan Glickman & Bruce Horwitz. (2011) Serum Markers in Acute Appendicitis. Journal of Surgical Research 168:1, pages 70-75.
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Marie Rubér, Manne Andersson, B. Fredrik Petersson, Gunnar Olaison, Roland E. Andersson & Christina Ekerfelt. (2010) Systemic Th17-like cytokine pattern in gangrenous appendicitis but not in phlegmonous appendicitis. Surgery 147:3, pages 366-372.
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Alex Kentsis, Yin Yin Lin, Kyle Kurek, Monica Calicchio, Yan Yan Wang, Flavio Monigatti, Fabien Campagne, Richard Lee, Bruce Horwitz, Hanno Steen & Richard Bachur. (2010) Discovery and Validation of Urine Markers of Acute Pediatric Appendicitis Using High-Accuracy Mass Spectrometry. Annals of Emergency Medicine 55:1, pages 62-70.e4.
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Ziya Cetinkaya, Suleyman Aydin, Yusuf Z. Cerrahoglu, Refik Ayten, Fazilet Erman & Erhan Aygen. (2009) Changes in appetite hormone (ghrelin) levels of saliva and serum in acute appendicitis cases before and after operation. Appetite 52:1, pages 104-107.
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Han-Ping Wu, Ching-Yuang Lin, Chin-Fu Chang, Yu-Jun Chang & Chin-Yi Huang. (2005) Predictive value of C-reactive protein at different cutoff levels in acute appendicitis. The American Journal of Emergency Medicine 23:4, pages 449-453.
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M. Almagor, A. Mintz, O. Sibirsky & A. Durst. (2004) Preoperative and postoperative levels of interleukin-6 in patients with acute appendicitis: comparison between open and laparoscopic appendectomy. Surgical Endoscopy 19:3, pages 331-333.
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