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Original

Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment

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Pages 31-44 | Received 29 Jun 2005, Accepted 14 Oct 2005, Published online: 08 Jul 2009

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Mercè Brunet & Olga Millán. (2021) Getting immunosuppression just right: the role of clinical biomarkers in predicting patient response post solid organ transplantation. Expert Review of Clinical Pharmacology 14:12, pages 1467-1479.
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Brenda CM de Winter, Ron AA Mathôt, Reinier M van Hest & Teun van Geler. (2007) Therapeutic drug monitoring of mycophenolic acid: does it improve patient outcome?. Expert Opinion on Drug Metabolism & Toxicology 3:2, pages 251-261.
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Articles from other publishers (23)

Wolfgang Winnicki, Andreas Fichtenbaum, Goran Mitulovič, Harald Herkner, Florina Regele, Michael Baier, Sieglinde Zelzer, Ludwig Wagner & Guerkan Sengoelge. (2022) Individualization of Mycophenolic Acid Therapy through Pharmacogenetic, Pharmacokinetic and Pharmacodynamic Testing. Biomedicines 10:11, pages 2882.
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Petra GlanderJohannes WaiserPia HambachFriederike BachmannKlemens BuddeKai-Uwe EckardtFrank FriedersdorffJens GaedekeSusanne KronChristine LorkowskiMarco MaiHans-H. NeumayerRobert PetersBirgit RudolphDanilo SchmidtKaiyin WuLutz Liefeldt. (2020) Inosine 5′-Monophosphate Dehydrogenase Activity for the Longitudinal Monitoring of Mycophenolic Acid Treatment in Kidney Allograft Recipients. Transplantation 105:4, pages 916-927.
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Stein BerganMercè BrunetDennis A. HesselinkKamisha L. Johnson-DavisPaweł K. KunickiFlorian LemaitrePierre MarquetMariadelfina MolinaroOfelia NocetiSmita PattanaikTomasz PawinskiChristoph SegerMaria ShipkovaJesse J. SwenTeun van GelderRaman VenkataramananEberhard WielandJean-Baptiste WoillardTom C. ZwartMarkus J. BartenKlemens BuddeMaja-Theresa DieterlenLaure ElensVincent HaufroidSatohiro MasudaOlga MillanTomoyuki MizunoDirk J. A. R. MoesMichael OellerichNicolas PicardLinda SalzmannBurkhard TönshoffRon H. N. van SchaikNils Tore VetheAlexander A. VinksPierre WallemacqAnders Åsberg & Loralie J. Langman. (2021) Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Therapeutic Drug Monitoring 43:2, pages 150-200.
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Rolf Anton Klaasen, Stein Bergan, Sara Bremer, Kristine Hole, Christine Berg Nordahl, Anders Mikal Andersen, Karsten Midtvedt, Morten Heier Skauby & Nils Tore Vethe. (2020) Pharmacodynamic assessment of mycophenolic acid in resting and activated target cell population during the first year after renal transplantation. British Journal of Clinical Pharmacology 86:6, pages 1100-1112.
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Yasuaki Mino, Takafumi Naito, Kumiko Shimoyama, Noriyoshi Ogawa & Junichi Kawakami. (2016) Mycophenolic acid exposure and complement fraction C3 influence inosine 5′-monophosphate dehydrogenase activity in systemic lupus erythematosus. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 54:4, pages 490-494.
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Stein Bergan, Sara Bremer & Nils Tore Vethe. (2016) Drug target molecules to guide immunosuppression. Clinical Biochemistry 49:4-5, pages 411-418.
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Petra Glander, Pia Hambach, Lutz Liefeldt & Klemens Budde. (2012) Inosine 5′-monophosphate dehydrogenase activity as a biomarker in the field of transplantation. Clinica Chimica Acta 413:17-18, pages 1391-1397.
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Isabelle Laverdière, Patrick Caron, Félix Couture, Chantal Guillemette & Éric Lévesque. (2011) Liquid Chromatography–Coupled Tandem Mass Spectrometry Based Assay to Evaluate Inosine-5′-monophosphate Dehydrogenase Activity in Peripheral Blood Mononuclear Cells from Stem Cell Transplant Recipients. Analytical Chemistry 84:1, pages 216-223.
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Michael Oellerich, Gunnar Brandhorst, Maria Shipkova & Eberhard Wieland. 2012. Therapeutic Drug Monitoring. Therapeutic Drug Monitoring 349 372 .
Hideaki Kagaya, Masatomo Miura, Mitsuru Saito, Tomonori Habuchi & Shigeru Satoh. (2010) Correlation of IMPDH1 Gene Polymorphisms with Subclinical Acute Rejection and Mycophenolic Acid Exposure Parameters on Day 28 after Renal Transplantation . Basic & Clinical Pharmacology & Toxicology 107:2, pages 631-636.
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Laurent R. Chiarelli, Mariadelfina Molinaro, Carmelo Libetta, Carmine Tinelli, Laura Cosmai, Giovanna Valentini, Antonio Dal Canton & Mario Regazzi. (2009) Inosine monophosphate dehydrogenase variability in renal transplant patients on long‐term mycophenolate mofetil therapy. British Journal of Clinical Pharmacology 69:1, pages 38-50.
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Sara Bremer, Nils T Vethe, Helge Rootwelt, Pål F Jørgensen, Jean Stenstrøm, Hallvard Holdaas, Karsten Midtvedt & Stein Bergan. (2009) Mycophenolate pharmacokinetics and pharmacodynamics in belatacept treated renal allograft recipients – a pilot study. Journal of Translational Medicine 7:1.
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Yasuaki Mino, Takafumi Naito, Atsushi Otsuka, Seiichiro Ozono, Yoshiyuki Kagawa & Junichi Kawakami. (2009) Inosine monophosphate dehydrogenase activity depends on plasma concentrations of mycophenolic acid and its glucuronides in kidney transplant recipients. Clinica Chimica Acta 409:1-2, pages 56-61.
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Ferdi Sombogaard, Ron H.N. van Schaik, Ron A. Mathot, Klemens Budde, Marloes van der Werf, Arnold G. Vulto, Willem Weimar, Petra Glander, Laurent Essioux & Teun van Gelder. (2009) Interpatient variability in IMPDH activity in MMF-treated renal transplant patients is correlated with IMPDH type II 3757T>C polymorphism. Pharmacogenetics and Genomics 19:8, pages 626-634.
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T. Rath & M. Küpper. (2009) Comparison of Inosine-Monophosphate-Dehydrogenase Activity in Patients With Enteric-Coated Mycophenolate Sodium or Mycophenolate Mofetil After Renal Transplantation. Transplantation Proceedings 41:6, pages 2524-2528.
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Sara Bremer, Nils T. Vethe, Helge Rootwelt & Stein Bergan. (2009) Expression of IMPDH1 is regulated in response to mycophenolate concentration. International Immunopharmacology 9:2, pages 173-180.
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Nils Tore Vethe, Sara Bremer, Helge Rootwelt & Stein Bergan. (2008) Pharmacodynamics of Mycophenolic Acid in CD4+ Cells: A Single-Dose Study of IMPDH and Purine Nucleotide Responses in Healthy Individuals. Therapeutic Drug Monitoring 30:6, pages 647-655.
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Sara Bremer, Randeep Mandla, Nils T. Vethe, Ingrid Rasmussen, Helge Rootwelt, Pål-D Line, Karsten Midtvedt & Stein Bergan. (2008) Expression of IMPDH1 and IMPDH2 After Transplantation and Initiation of Immunosuppression. Transplantation 85:1, pages 55-61.
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David Czock, Franz Maximilian Rasche, Alexander Carius, Petra Glander, Klemens Budde, Steffen Bauer, Frieder Keller & Lutz von Mμller. (2013) Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid After Enteric‐Coated Mycophenolate Versus Mycophenolate Mofetil in Patients With Progressive IgA Nephritis. The Journal of Clinical Pharmacology 47:7, pages 850-859.
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Sara Bremer, Helge Rootwelt & Stein Bergan. (2007) Real-Time PCR Determination of IMPDH1 and IMPDH2 Expression in Blood Cells. Clinical Chemistry 53:6, pages 1023-1029.
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Nicole A Weimert, Maurits DeRotte, Rita R Alloway, E Steve Woodle & Alexander A Vinks. (2007) Monitoring of Inosine Monophosphate Dehydrogenase Activity as a Biomarker for Mycophenolic Acid Effect: Potential Clinical Implications. Therapeutic Drug Monitoring 29:2, pages 141-149.
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J. Michael Tredger, Nigel W. Brown & Anil Dhawan. (2006) Immunosuppression in pediatric solid organ transplantation: Opportunities, risks, and management. Pediatric Transplantation 10:8, pages 879-892.
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J.Y. Kim, S.Y. Yoon, J. Park & Y.S. Kim. (2006) Mycophenolic Acid Induces Islet Apoptosis by Regulating Mitogen-Activated Protein Kinase Activation. Transplantation Proceedings 38:10, pages 3277-3279.
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