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ORIGINAL ARTICLE

Experimental hyperhomocysteinemia disturbs bone metabolism in rats

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Pages 748-756 | Received 11 Jan 2007, Accepted 13 Mar 2007, Published online: 08 Jul 2009

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Read on this site (2)

Neetu Tyagi, Thomas P Vacek, John T Fleming, Jonathan C Vacek & Suresh C Tyagi. (2011) Hyperhomocysteinemia decreases bone blood flow. Vascular Health and Risk Management 7, pages 31-35.
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Wolfgang Herrmann & Markus Herrmann. (2008) Is hyperhomocysteinemia a risk factor for osteoporosis?. Expert Review of Endocrinology & Metabolism 3:3, pages 309-313.
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Articles from other publishers (18)

Asha Bhardwaj, Leena Sapra, Bhupendra Verma & Rupesh K. Srivastava. 2022. Homocysteine Metabolism in Health and Disease. Homocysteine Metabolism in Health and Disease 71 95 .
Roman Pawlak. (2021) Vitamin B12 status is a risk factor for bone fractures among vegans. Medical Hypotheses 153, pages 110625.
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Zhongxin Zhu, Changhua Liu, Xiao’e Li & Xiaocong Yao. (2020) Association between plasma total homocysteine level within normal range and bone mineral density in adults. Journal of Orthopaedic Surgery and Research 15:1.
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Diana Cabrera, Marlena Kruger, Frances M. Wolber, Nicole C. Roy & Karl Fraser. (2020) Effects of short- and long-term glucocorticoid-induced osteoporosis on plasma metabolome and lipidome of ovariectomized sheep. BMC Musculoskeletal Disorders 21:1.
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Alexander Ströhle, Margrit Richter, Marcela González‐Gross, Monika Neuhäuser‐Berthold, Karl‐Heinz Wagner, Eva Leschik‐Bonnet & Sarah Egert. (2019) The Revised D‐A‐CH‐Reference Values for the Intake of Vitamin B 12 : Prevention of Deficiency and Beyond . Molecular Nutrition & Food Research 63:6.
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Mitsuru Saito & Keishi Marumo. (2018) The Effects of Homocysteine on the Skeleton. Current Osteoporosis Reports 16:5, pages 554-560.
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Petar Milovanovic, Dragan Hrncic, Ksenija Radotic, Mira Stankovic, Dragosav Mutavdzic, Danijela Djonic, Aleksandra Rasic-Markovic, Dragan Djuric, Olivera Stanojlovic & Marija Djuric. (2017) Moderate hyperhomocysteinemia induced by short-term dietary methionine overload alters bone microarchitecture and collagen features during growth. Life Sciences 191, pages 9-16.
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Jyotirmaya Behera, Jyoti Bala, Mohammed Nuru, Suresh C. Tyagi & Neetu Tyagi. (2017) Homocysteine as a Pathological Biomarker for Bone Disease. Journal of Cellular Physiology 232:10, pages 2704-2709.
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Eva Feigerlova, Lea Demarquet & Jean-Louis Guéant. (2016) One carbon metabolism and bone homeostasis and remodeling: A review of experimental research and population studies. Biochimie 126, pages 115-123.
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Ari KimJun Hee LeeJi Young LeeYoung Min OhSung-Nam HongHoon ChoiEun-Ae JaeHae-Hyeog LeeHeung Yeol Kim. (2013) Association between Serum Homocysteine Concentrations and Bone Mineral Density in Middle Aged Women. The Journal of Korean Society of Menopause 19:2, pages 81.
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Hanan F. Al-Saeed. (2012) Effects of folic acid supplementation on bone turnover markers in male rats subjected to experimental hyperhomocysteinemia. Medical Research Journal 11:2, pages 48-53.
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Stergios A. Polyzos, Athanasios D. Anastasilakis, Zoe Efstathiadou, Ioannis Litsas, Marina Kita, Athanasios Panagiotou, Athanasios Papatheodorou, Georgios Arsos, Efstratios Moralidis, Georgios Barmpalios, Efthimia Zafeiriadou, Efthimia Triantafillidou, Eleni Makrigiannaki & Evangelos Terpos. (2009) Serum homocysteine, folate and vitamin B12 in patients with Paget’s disease of bone: the effect of zoledronic acid. Journal of Bone and Mineral Metabolism 28:3, pages 314-319.
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Roman Thaler, Silvia Spitzer, Monika Rumpler, Nadja Fratzl-Zelman, Klaus Klaushofer, Eleftherios P. Paschalis & Franz Varga. (2010) Differential effects of homocysteine and beta aminopropionitrile on preosteoblastic MC3T3-E1 cells. Bone 46:3, pages 703-709.
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Joerg H. Holstein, Markus Herrmann, Christina Splett, Wolfgang Herrmann, Patric Garcia, Tina Histing, Moritz Klein, Karsten Kurz, Thomas Siebel, Tim Pohlemann & Michael D. Menger. (2010) Hyperhomocysteinemia is not associated with reduced bone quality in humans with hip osteoarthritis. Clinical Chemistry and Laboratory Medicine 48:6.
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L. Claes, J. Schmalenbach, M. Herrmann, I. Ölkü, P. Garcia, T. Histing, R. Obeid, H. Schorr, W. Herrmann, T. Pohlemann, M. D. Menger & J. H. Holstein. (2009) Hyperhomocysteinemia Is Associated with Impaired Fracture Healing in Mice. Calcified Tissue International 85:1, pages 17-21.
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Bart L. T. Vaes, Carolien Lute, Henk J. Blom, Nathalie Bravenboer, Teun J. de Vries, Vincent Everts, Rosalie A. Dhonukshe-Rutten, Michael Müller, Lisette C. P. G. M. de Groot & Wilma T. Steegenga. (2009) Vitamin B12 Deficiency Stimulates Osteoclastogenesis via Increased Homocysteine and Methylmalonic Acid. Calcified Tissue International 84:5, pages 413-422.
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Wolfgang Herrmann, Rima Obeid, Heike Schorr, Ulrich Hübner, Jürgen Geisel, Marga Sand-Hill, Nayyar Ali & Markus Herrmann. (2009) Enhanced bone metabolism in vegetarians – the role of vitamin B12 deficiency. Clinical Chemistry and Laboratory Medicine 47:11.
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Pooneh Salari, Bagher Larijani & Mohammad Abdollahi. (2008) Association of hyperhomocysteinemia with osteoporosis: a systematic review. Therapy 5:2, pages 215-222.
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