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Scandinavian Journal of Clinical and Laboratory Investigation Volume 68, 2008 - Issue 5
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Original Article

The reduced folate carrier (RFC1) 80G>A and folate hydrolase 1 (FOLH1) 1561C>T polymorphisms and the risk of colorectal cancer: A nested case‐referent study

V. Eklöf Department of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden
,
B. Van Guelpen Department of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden
,
J. Hultdin Department of Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden
,
I. Johansson Department of Odontology, Cariology, Umeå University, Umeå, Sweden
,
G. Hallmans Department of Public Health and Clinical Medicine, Nutrition Research, Umeå University, Umeå, Sweden
&
R. Palmqvist Department of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden
Pages 393-401 | Received 25 Sep 2007, Accepted 12 Nov 2007, Published online: 08 Jul 2009

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Fabio Coppedè, Andrea Stoccoro, Alessandro Lazzarotti, Roberto Spisni & Lucia Migliore. (2018) Investigation of GHSR and GHRL Methylation in Colorectal Cancer. Epigenomics 10:12, pages 1525-1539.
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Articles from other publishers (16)

Xixiang Wang, Ying Wang, Xiaojun Ma, Shaobo Zhou, Jingjing Xu, Yujie Guo, Lu Liu, Yu Liu, Lifang Gao & Linhong Yuan. (2023) Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults. Experimental Gerontology 178, pages 112208.
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Lingyan Xu, Zhiqiang Qin, Feng Wang, Shuhui Si, Lele Li, Peinan Lin, Xiao Han, Xiaomin Cai, Haiwei Yang & Yanhong Gu. (2017) Methylenetetrahydrofolate reductase C677T polymorphism and colorectal cancer susceptibility: a meta-analysis. Bioscience Reports 37:6.
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Daniel Cummings, Kevin Dowling, Noah Silverstein, Alexandra Tanner, Hamdi Eryilmaz, Jordan Smoller & Joshua Roffman. (2017) A Cross-Sectional Study of Dietary and Genetic Predictors of Blood Folate Levels in Healthy Young Adults. Nutrients 9:9, pages 994.
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Robin Myte, Björn Gylling, Jenny Häggström, Jörn Schneede, Per Magne Ueland, Göran Hallmans, Ingegerd Johansson, Richard Palmqvist & Bethany Van Guelpen. (2017) Untangling the role of one-carbon metabolism in colorectal cancer risk: a comprehensive Bayesian network analysis. Scientific Reports 7:1.
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Donghong Zhang, Xuemei Wen, Wei Wu, Ye Guo & Wei Cui. (2015) Elevated Homocysteine Level and Folate Deficiency Associated with Increased Overall Risk of Carcinogenesis: Meta-Analysis of 83 Case-Control Studies Involving 35,758 Individuals. PLOS ONE 10:5, pages e0123423.
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JONG WOO KIM, YOUNG JOO JEON, MOON JU JANG, JUNG O KIM, SO YOUNG CHONG, KWANG HYUN KO, SEONG GYU HWANG, DOYEUN OH, JISU OH & NAM KEUN KIM. (2015) Association between folate metabolism-related polymorphisms and colorectal cancer risk. Molecular and Clinical Oncology 3:3, pages 639-648.
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Fabio Coppedè, Pierpaola Tannorella, Gloria Tognoni, Silvia Bagnoli, Paolo Bongioanni, Benedetta Nacmias, Gabriele Siciliano, Sandro Sorbi, Ubaldo Bonuccelli & Lucia Migliore. (2014) A Pilot Study Evaluating the Contribution of SLC19A1 ( RFC-1 ) 80G>A Polymorphism to Alzheimer’s Disease in Italian Caucasians . BioMed Research International 2014, pages 1-6.
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MENGMENG ZHAO, XUELIAN LI, CHENGZHONG XING & BAOSEN ZHOU. (2013) Association of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms with colorectal cancer risk: A meta-analysis. Biomedical Reports 1:5, pages 781-791.
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Lynnette FergusonPeter Eck. 2013. Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition. Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition 25 82 .
Jane C. Figueiredo, A. Joan Levine, Jimmy W. Crott, James Baurley & Robert W. Haile. (2013) Folate‐genetics and colorectal neoplasia: What we know and need to know next. Molecular Nutrition & Food Research 57:4, pages 607-627.
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Zan Teng, Lei Wang, Shuang Cai, Ping Yu, Jin Wang, Jing Gong & Yunpeng Liu. (2013) The 677C>T (rs1801133) Polymorphism in the MTHFR Gene Contributes to Colorectal Cancer Risk: A Meta-Analysis Based on 71 Research Studies. PLoS ONE 8:2, pages e55332.
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Diana T. Lau, Luke B. Hesson, Murray D. Norris, Glenn M. Marshall, Michelle Haber & Lesley J. Ashton. (2012) Prognostic Significance of Promoter DNA Methylation in Patients with Childhood Neuroblastoma. Clinical Cancer Research 18:20, pages 5690-5700.
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Xuewen Sheng, Yanxi Zhang, Erjiang Zhao, Su Lu, Xiaoli Zheng, Hong Ge & Weiquan Lu. (2012) MTHFR C677T polymorphism contributes to colorectal cancer susceptibility: evidence from 61 case–control studies. Molecular Biology Reports 39:10, pages 9669-9679.
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Ana Lívia Silva Galbiatti, Mariangela Torreglosa Ruiz, José Victor Maniglia, Luis Sérgio Raposo, Érika Cristina Pavarino-Bertelli & Eny Maria Goloni-Bertollo. (2012) Head and neck cancer: genetic polymorphisms and folate metabolism. Brazilian Journal of Otorhinolaryngology 78:1, pages 132-139.
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A. Joan Levine, Won Lee, Jane C. Figueiredo, David V. Conti, David J. Vandenberg, Brian D. Davis, Christopher K. Edlund, Susanne M. Henning, David Heber, Mariana C. Stern & Robert W. Haile. (2011) Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case–control study. Cancer Causes & Control 22:4, pages 541-552.
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Dong Yong Kil, Brittany M. Vester Boler, Carolyn J. Apanavicius, Lawrence B. Schook & Kelly S. Swanson. (2010) Gene Expression Profiles of Colonic Mucosa in Healthy Young Adult and Senior Dogs. PLoS ONE 5:9, pages e12882.
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