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Parveen Salahuddin, Rizwan Hasan Khan & Vladimir N. Uversky. (2020) Comprehensive analysis of the molecular docking of small molecule inhibitors to the Aβ1–40 peptide and its Osaka-mutant: insights into the molecular mechanisms of Aβ-peptide inhibition. Journal of Biomolecular Structure and Dynamics 38:15, pages 4536-4566.
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Chi-Hua Yen, Cheng-Hsin Wang, Wen-Tzu Wu & Hsiao-Ling Chen. (2017) Fructo-oligosaccharide improved brain β-amyloid, β-secretase, cognitive function, and plasma antioxidant levels in D-galactose-treated Balb/cJ mice. Nutritional Neuroscience 20:4, pages 228-237.
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Patricia Regina Manzine, Matheus da Silva Souza & Márcia Regina Cominetti. (2016) Bace1 Levels Are Increased in Plasma Of Alzheimer’S Disease Patients Compared with Matched Cognitively Healthy Controls. Personalized Medicine 13:6, pages 531-540.
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Hezekiel M. Kumalo, Soumendranath Bhakat & Mahmoud E. Soliman. (2016) Investigation of flap flexibility of β-secretase using molecular dynamic simulations. Journal of Biomolecular Structure and Dynamics 34:5, pages 1008-1019.
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Articles from other publishers (50)
Nikolay V. Shcherbakov, Polina F. Kotikova, Elena I. Chikunova, Dmitry V. Dar'in, Vadim Yu. Kukushkin & Alexey Yu. Dubovtsev. (2023)
Gold‐Catalyzed Annulation of Ynamides with Aminocarbonyls as a Route to 2‐Aminoquinolines Diversely Substituted at the 4
th
‐Position
. Advanced Synthesis & Catalysis 365:14, pages 2428-2434.
Crossref
Crossref
Dasom Kong, Ki Hoon Park, Da-Hyun Kim, Nam Gyo Kim, Seung-Eun Lee, Nari Shin, Myung Geun Kook, Young Bong Kim & Kyung-Sun Kang. (2023) Cortical-blood vessel assembloids exhibit Alzheimer’s disease phenotypes by activating glia after SARS-CoV-2 infection. Cell Death Discovery 9:1.
Crossref
Crossref
X Wang, M Li & Y Hu. (2023) miR-29c-3p Attenuates β-Amyloid-Induced Neurotoxicity in Alzheimer’s Disease Through Regulating β-Site Amyloid Precursor Protein-Cleaving Enzyme 1. Physiological Research, pages 833-841.
Crossref
Crossref
Giovanni Pagni, Claudia Tagliarini, Manuel Glauco Carbone, Bruno Pietro Imbimbo, Donatella Marazziti & Nunzio Pomara. (2022) Different Sides of Depression in the Elderly: An In-depth View on the Role of Aβ Peptides. Current Medicinal Chemistry 29:36, pages 5731-5757.
Crossref
Crossref
Yi Zhang, Xiaoqin Gao, Xue Bai, Shanshan Yao, Yan-Zhong Chang & Guofen Gao. (2022) The emerging role of furin in neurodegenerative and neuropsychiatric diseases. Translational Neurodegeneration 11:1.
Crossref
Crossref
John Galvin, Elizabeth Curran, Francisco Arteaga, Alicia Goossens, Nicki Aubuchon-Endsley, Michael A McMurray, Jeffrey Moore, Kirk C Hansen, Heidi J Chial, Huntington Potter, Jeffrey L Brodsky & Christina M Coughlan. (2022) Proteasome activity modulates amyloid toxicity. FEMS Yeast Research 22:1.
Crossref
Crossref
Linbin Dai & Yong Shen. (2021) Insights into T‐cell dysfunction in Alzheimer's disease. Aging Cell 20:12.
Crossref
Crossref
Bradley J. Baranowski, Grant C. Hayward, Daniel M. Marko & Rebecca E. K. MacPherson. (2021) Examination of BDNF Treatment on BACE1 Activity and Acute Exercise on Brain BDNF Signaling. Frontiers in Cellular Neuroscience 15.
Crossref
Crossref
Donovan A. McGrowder, Fabian Miller, Kurt Vaz, Chukwuemeka Nwokocha, Cameil Wilson-Clarke, Melisa Anderson-Cross, Jabari Brown, Lennox Anderson-Jackson, Lowen Williams, Lyndon Latore, Rory Thompson & Ruby Alexander-Lindo. (2021) Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease: Current Evidence and Future Perspectives. Brain Sciences 11:2, pages 215.
Crossref
Crossref
Seyedeh Nazanin Hajjri, Saeed Sadigh-Eteghad, Masoud Mehrpour, Fatemeh Moradi, Dariush Shanehbandi & Mehdi Mehdizadeh. (2020) Beta-Amyloid-Dependent miRNAs as Circulating Biomarkers in Alzheimer’s Disease: a Preliminary Report. Journal of Molecular Neuroscience 70:6, pages 871-877.
Crossref
Crossref
Xiaolu Liu, Zhitao Feng, Lipeng Du, Yaguang Huang, Jinwen Ge, Yihui Deng & Zhigang Mei. (2019) The Potential Role of MicroRNA-124 in Cerebral Ischemia Injury. International Journal of Molecular Sciences 21:1, pages 120.
Crossref
Crossref
Marc D. Tambini, Wen Yao & Luciano D'Adamio. (2019)
Facilitation of glutamate, but not
GABA
, release in Familial Alzheimer's
APP
mutant Knock‐in rats with increased β‐cleavage of
APP
. Aging Cell 18:6.
Crossref
Crossref
Inmaculada Lopez-Font, Claudia P. Boix, Henrik Zetterberg, Kaj Blennow & Javier Sáez-Valero. (2019) Characterization of Cerebrospinal Fluid BACE1 Species. Molecular Neurobiology 56:12, pages 8603-8616.
Crossref
Crossref
Yaqi Wang, Yi Zhang, Xiaomin Zhang, Tingting Yang, Chengeng Liu & Peichang Wang. (2019) Alcohol Dehydrogenase 1B Suppresses β-Amyloid-Induced Neuron Apoptosis. Frontiers in Aging Neuroscience 11.
Crossref
Crossref
Alex J. Yang, Grant C. Hayward & Rebecca E. K. MacPherson. (2019)
Acute exercise and brain
BACE
1 protein content: a time course study
. Physiological Reports 7:8, pages e14084.
Crossref
Crossref
Rizwan Hasan Khan, Mohammad Khursheed Siddiqi, Vladimir N. Uversky & Parveen Salahuddin. (2019) Molecular docking of Aβ1–40 peptide and its Iowa D23N mutant using small molecule inhibitors: Possible mechanisms of Aβ-peptide inhibition. International Journal of Biological Macromolecules 127, pages 250-270.
Crossref
Crossref
Li-Ge Zhao, Ying Tang, Jia-Ze Tan, Jing-Wen Wang, Guo-Jun Chen & Bing-Lin Zhu. (2018) The effect of NR4A1 on APP metabolism and tau phosphorylation. Genes & Diseases 5:4, pages 342-348.
Crossref
Crossref
Zhigang Zhong, Kui Yuan, Xiaoxin Tong, Jun Hu, Zubiao Song, Guogao Zhang, Xiaobo Fang & Weixi Zhang. (2018) MiR-16 attenuates β-amyloid-induced neurotoxicity through targeting β-site amyloid precursor protein-cleaving enzyme 1 in an Alzheimer’s disease cell model. NeuroReport 29:16, pages 1365-1372.
Crossref
Crossref
Wataru Araki, Yumiko M Araki & Hidehiro Mizusawa. (2018)
Potential value of soluble APP
α
and APP
β
in CSF as biomarkers of dementia disorders: Unresolved issues and perspectives
. Neurology and Clinical Neuroscience 6:4, pages 89-93.
Crossref
Crossref
Bradley J. Baranowski, Kirsten N. Bott & Rebecca E. K. MacPherson. (2018) Evaluation of neuropathological effects of a high-fat high-sucrose diet in middle-aged male C57BL6/J mice. Physiological Reports 6:11, pages e13729.
Crossref
Crossref
Yong Shen, Haibo Wang, Qiying Sun, Hailan Yao, Andrew P. Keegan, Mike Mullan, Jeffrey Wilson, Simone Lista, Thomas Leyhe, Christoph Laske, Dan Rujescu, Allan Levey, Anders Wallin, Kaj Blennow, Rena Li & Harald Hampel. (2018) Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer’s Disease Dementia in Individuals With Mild Cognitive Impairment. Biological Psychiatry 83:5, pages 447-455.
Crossref
Crossref
Wataru Araki, Kotaro Hattori, Kazutomi Kanemaru, Yuma Yokoi, Yoshie Omachi, Harumasa Takano, Masuhiro Sakata, Sumiko Yoshida, Tadashi Tsukamoto, Miho Murata, Yuko Saito, Hiroshi Kunugi, Yu-ichi Goto, Utako Nagaoka, Masahiro Nagao, Takashi Komori, Kunimasa Arima, Kenji Ishii, Shigeo Murayama, Hiroshi Matsuda, Hisateru Tachimori, Yumiko M. Araki & Hidehiro Mizusawa. (2017) Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders. Biomarker Research 5:1.
Crossref
Crossref
Rebecca E. K. MacPherson. (2017) Filling the void: a role for exercise-induced BDNF and brain amyloid precursor protein processing. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 313:5, pages R585-R593.
Crossref
Crossref
Ho-Chen Lin, Ming-Yi Ho, Chao-Ming Tsen, Chien-Chu Huang, Chin-Ching Wu, Yuh-Jeen Huang, I-Lun Hsiao & Chun-Yu Chuang. (2017) From the Cover: Comparative Proteomics Reveals Silver Nanoparticles Alter Fatty Acid Metabolism and Amyloid Beta Clearance for Neuronal Apoptosis in a Triple Cell Coculture Model of the Blood–Brain Barrier. Toxicological Sciences 158:1, pages 151-163.
Crossref
Crossref
Cui Hao, Wei Wang, Shuyao Wang, Lijuan Zhang & Yunliang Guo. (2017) An Overview of the Protective Effects of Chitosan and Acetylated Chitosan Oligosaccharides against Neuronal Disorders. Marine Drugs 15:4, pages 89.
Crossref
Crossref
Wataru Araki. (2016) Post-translational regulation of the β-secretase BACE1. Brain Research Bulletin 126, pages 170-177.
Crossref
Crossref
MINA KAZEMZADEH, REZA SAFARALIZADEH & AYLA VALINEZHAD ORANG. (2015) LncRNAs: emerging players in gene regulation and disease pathogenesis. Journal of Genetics 94:4, pages 771-784.
Crossref
Crossref
R. E. K. MacPherson, P. Baumeister, W. T. Peppler, D. C. Wright & J. P. Little. (2015) Reduced cortical BACE1 content with one bout of exercise is accompanied by declines in AMPK, Akt, and MAPK signaling in obese, glucose-intolerant mice. Journal of Applied Physiology 119:10, pages 1097-1104.
Crossref
Crossref
Yaoqian Pan, Ruizhu Liu, Erin Terpstra, Yanqing Wang, Fangfang Qiao, Jin Wang, Yigang Tong & Bo Pan. (2015) Dysregulation and Diagnostic Potential of microRNA in Alzheimer’s Disease. Journal of Alzheimer's Disease 49:1, pages 1-12.
Crossref
Crossref
Yongyao Fu, Deming Zhao, Bo Pan, Jihong Wang, Yongyong Cui, Fushan Shi, Chunyu Wang, Xiaoming Yin, Xiangmei Zhou & Lifeng Yang. (2015) Proteomic Analysis of Protein Expression Throughout Disease Progression in a Mouse Model of Alzheimer’s Disease. Journal of Alzheimer's Disease 47:4, pages 915-926.
Crossref
Crossref
Simone Lista, Sid E. O’Bryant, Kaj Blennow, Bruno Dubois, Jacques Hugon, Henrik Zetterberg & Harald Hampel. (2015) Biomarkers in Sporadic and Familial Alzheimer’s Disease. Journal of Alzheimer's Disease 47:2, pages 291-317.
Crossref
Crossref
Yongyao Fu, Deming Zhao & Lifeng Yang. (2014) Protein-Based Biomarkers in Cerebrospinal Fluid and Blood for Alzheimer’s Disease. Journal of Molecular Neuroscience 54:4, pages 739-747.
Crossref
Crossref
Christopher LaustedInyoul LeeYong ZhouShizhen QinJaeyun SungNathan D. PriceLeroy HoodKai Wang. (2014) Systems Approach to Neurodegenerative Disease Biomarker Discovery. Annual Review of Pharmacology and Toxicology 54:1, pages 457-481.
Crossref
Crossref
Jung Kwon Lee, Eunice C. Y. Li-Chan, Joong-Kyun Jeon & Hee-Guk Byun. 2014. Seafood Processing By-Products. Seafood Processing By-Products
35
62
.
Yong Shen, Libang Yang & Rena Li. (2013) What does complement do in Alzheimer’s disease? Old molecules with new insights. Translational Neurodegeneration 2:1.
Crossref
Crossref
Minzi Deng, Wanxia He, Ya Tan, Hailong Han, Xiangyou Hu, Kun Xia, Zhuohua Zhang & Riqiang Yan. (2013) Increased Expression of Reticulon 3 in Neurons Leads to Reduced Axonal Transport of β Site Amyloid Precursor Protein-cleaving Enzyme 1. Journal of Biological Chemistry 288:42, pages 30236-30245.
Crossref
Crossref
Ratih Pangestuti & Se-Kwon Kim. (2013) Marine-derived bioactive materials for neuroprotection. Food Science and Biotechnology 22:5, pages 1-12.
Crossref
Crossref
Shailendra Kapoor. (2013) Emerging new biomarkers of Alzheimer's disease. International Journal of Geriatric Psychiatry 28:8, pages 880-880.
Crossref
Crossref
Feng Yu, Bo Xu, Chenghui Song, Liu Ji & Xianliang Zhang. (2013) Treadmill exercise slows cognitive deficits in aging rats by antioxidation and inhibition of amyloid production. NeuroReport 24:6, pages 342-347.
Crossref
Crossref
Harald Hampel & S. Lista. (2013) Use of biomarkers and imaging to assess pathophysiology, mechanisms of action and target engagement. The Journal of nutrition, health and aging 17:1, pages 54-63.
Crossref
Crossref
Harald Hampel, Simone Lista & Zaven S. Khachaturian. (2012) Development of biomarkers to chart all Alzheimer's disease stages: The royal road to cutting the therapeutic Gordian Knot. Alzheimer's & Dementia 8:4, pages 312-336.
Crossref
Crossref
Liqin Zhao, Todd E. Morgan, Zisu Mao, Sharon Lin, Enrique Cadenas, Caleb E. Finch, Christian J. Pike, Wendy J. Mack & Roberta D. Brinton. (2012) Continuous versus Cyclic Progesterone Exposure Differentially Regulates Hippocampal Gene Expression and Functional Profiles. PLoS ONE 7:2, pages e31267.
Crossref
Crossref
Jeffrey L. Cummings. (2011) Biomarkers in Alzheimer's disease drug development. Alzheimer's & Dementia 7:3.
Crossref
Crossref
Zhiyou Cai, Yu Zhao, Shengtao Yao & Bin Zhao. (2011) Increases in β-amyloid protein in the hippocampus caused by diabetic metabolic disorder are blocked by minocycline through inhibition of NF-κB pathway activation. Pharmacological Reports 63:2, pages 381-391.
Crossref
Crossref
Yan Cai, Kun Xiong, Xue‐Mei Zhang, Huaibin Cai, Xue‐Gang Luo, Jia‐Chun Feng, Richard W. Clough, Robert G. Struble, Peter R. Patrylo, Yaping Chu, Jeffrey H. Kordower & Xiao‐Xin Yan. (2010) β‐Secretase‐1 elevation in aged monkey and Alzheimer’s disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β‐amyloid accumulation. European Journal of Neuroscience 32:7, pages 1223-1238.
Crossref
Crossref
Walter Maetzler & Daniela Berg. 2010. Biomarkers. Biomarkers
89
117
.
Ratih Pangestuti & Se-Kwon Kim. (2010) Neuroprotective Properties of Chitosan and Its Derivatives. Marine Drugs 8:7, pages 2117-2128.
Crossref
Crossref
Neal R. Cutler, John J. Sramek, Michael F. Murphy, Henry RiordanSrSr, Peter Bieck & Angelico Carta. 2010. Critical Pathways to Success in CNS Drug Development. Critical Pathways to Success in CNS Drug Development
101
166
.
C. F. Wright, A. Hall, F. E. Matthews & C. Brayne. (2009) Biomarkers, Dementia, and Public Health. Annals of the New York Academy of Sciences 1180:1, pages 11-19.
Crossref
Crossref
H. Hampel & K. Broich. (2009) Enrichment of MCI and early Alzheimer's disease treatment trials using neurochemical & imaging candidate biomarkers. The Journal of nutrition, health and aging 13:4, pages 373-375.
Crossref
Crossref