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Original Article

Metformin has no major effects on glucose homeostasis in pregnant women with PCOS: results of a randomized double‐blind study

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Pages 771-776 | Received 07 Mar 2008, Accepted 01 Jun 2008, Published online: 08 Jul 2009

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Torstein B. Rø, Heidi V. Ludvigsen, Sven M. Carlsen & Eszter Vanky. (2012) Growth, body composition and metabolic profile of 8-year-old children exposed to metformin in utero. Scandinavian Journal of Clinical and Laboratory Investigation 72:7, pages 570-575.
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Articles from other publishers (26)

Christine Newman, Louise Rabbitt, Adesuwa Ero & Fidelma P. Dunne. (2023) Focus on Metformin: Its Role and Safety in Pregnancy and Beyond. Drugs 83:11, pages 985-999.
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Hui Yu, Jinling Sun & Honglei Hu. (2023) Prophylactic administration of metformin reduces gestational diabetes mellitus incidence in the high-risk populations: a meta-analysis. Irish Journal of Medical Science (1971 -).
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Ketil Arne Espnes, Arne Hønnås, Tone S. Løvvik, Per Ole M. Gundersen, Audhild Naavik, Eirik Skogvoll, Andreas A. Westin, Olav Spigset & Eszter Vanky. (2022) Metformin serum concentrations during pregnancy and post partum – A clinical study in patients with polycystic ovary syndrome. Basic & Clinical Pharmacology & Toxicology 130:3, pages 415-422.
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Qi Cao, Yuanyuan Hu, Jing Fu, Xin Huang, Lukanxuan Wu, Jiani Zhang & Wei Huang. (2021) Gestational metformin administration in women with polycystic ovary syndrome: A systematic review and meta‐analysis of randomized control studies. Journal of Obstetrics and Gynaecology Research 47:12, pages 4148-4157.
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Yongjie Liu, Mengyang Du, Yuexin Gan, Shihua Bao, Liping Feng & Jun Zhang. (2021) Triglyceride Induced Metabolic Inflammation: Potential Connection of Insulin Resistance and Recurrent Pregnancy Loss. Frontiers in Endocrinology 12.
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G. Zito, L. Della Corte, P. Giampaolino, M. Terzic, S. Terzic, F. Di Guardo, G. Ricci, I. Della Pietà, G. Maso & S. Garzon. (2020) Gestational diabetes mellitus: Prevention, diagnosis and treatment. A fresh look to a busy corner. Journal of Neonatal-Perinatal Medicine 13:4, pages 529-541.
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Iramar Baptistella do Nascimento, Willian Barbosa Sales, Guilherme Dienstmann, Matheus Leite Ramos de Souza, Raquel Fleig & Jean Carl Silva. (2020) Metformin for prevention of cesarean delivery and large-for-gestational-age newborns in non-diabetic obese pregnant women: a randomized clinical trial. Archives of Endocrinology and Metabolism 64:3, pages 290-297.
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Suhail A.R. Doi, Luis Furuya‐Kanamori, Egon Toft, Omran A.H. Musa, Nazmul Islam, Justin Clark & Lukman Thalib. (2019) Metformin in pregnancy to avert gestational diabetes in women at high risk: Meta‐analysis of randomized controlled trials. Obesity Reviews 21:1.
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Razieh Bidhendi Yarandi, Samira Behboudi-Gandevani, Mina Amiri & Fahimeh Ramezani Tehrani. (2019) Metformin therapy before conception versus throughout the pregnancy and risk of gestational diabetes mellitus in women with polycystic ovary syndrome: a systemic review, meta-analysis and meta-regression. Diabetology & Metabolic Syndrome 11:1.
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Tone S Løvvik, Sven M Carlsen, Øyvind Salvesen, Berglind Steffensen, Marie Bixo, Francisco Gómez-Real, Marianne Lønnebotn, Kristin V Hestvold, Renata Zabielska, Angelica L Hirschberg, Anastasia Trouva, Solveig Thorarinsdottir, Sissel Hjelle, Ann Hilde Berg, Frida Andræ, Inger S Poromaa, Johanna Mohlin, Maria Underdal & Eszter Vanky. (2019) Use of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial. The Lancet Diabetes & Endocrinology 7:4, pages 256-266.
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Ahmed Elmaraezy, Abdelrahman Ibrahim Abushouk, Amany Emara, Omar Elshahat, Hussien Ahmed & Magdy I. Mostafa. (2017) Effect of metformin on maternal and neonatal outcomes in pregnant obese non-diabetic women: A meta-analysis. International Journal of Reproductive BioMedicine 15:8, pages 461-470.
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Enton Kaculini, lma Idrizi, Marsida Duli, Alketa Koroshi, Alma Shehu, Nereida Spahia & Myftar Barbullushi. (2016) Preeclampsia: from Pathophysiology to Treatment. BANTAO Journal 14:2, pages 53-59.
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Xian-Ling Zeng, Ya-Fei Zhang, Quan Tian, Yan Xue & Rui-Fang An. (2016) Effects of metformin on pregnancy outcomes in women with polycystic ovary syndrome. Medicine 95:36, pages e4526.
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Jens H. Stupin. (2016) Weniger Gewichtszunahme bei adipösen Schwangeren mit Metformin. Info Diabetologie 10:3, pages 14-15.
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Argyro Syngelaki, Kypros H. Nicolaides, Jyoti Balani, Steve Hyer, Ranjit Akolekar, Reena Kotecha, Alice Pastides & Hassan Shehata. (2016) Metformin versus Placebo in Obese Pregnant Women without Diabetes Mellitus. New England Journal of Medicine 374:5, pages 434-443.
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Ingrid Hov Odsæter, Arne Åsberg, Eszter Vanky & Sven Magnus Carlsen. (2015) HbA1c as screening for gestational diabetes mellitus in women with polycystic ovary syndrome. BMC Endocrine Disorders 15:1.
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Yadava B. Jeve, Justin C. Konje & Anjum Doshani. (2015) Placental dysfunction in obese women and antenatal surveillance strategies. Best Practice & Research Clinical Obstetrics & Gynaecology 29:3, pages 350-364.
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Ragnhild Helseth, Eszter Vanky, Solhild Stridsklev, Christina Vogt & Sven M Carlsen. (2014) Maternal and fetal insulin levels at birth in women with polycystic ovary syndrome: data from a randomized controlled study on metformin. European Journal of Endocrinology 170:5, pages 769-775.
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Zhihong Zhuo, Aiming Wang & Huimin Yu. (2014) Effect of Metformin Intervention during Pregnancy on the Gestational Diabetes Mellitus in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Journal of Diabetes Research 2014, pages 1-13.
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Scott M. Nelson & Lucilla Poston. 2012. Maternal Obesity. Maternal Obesity 179 198 .
GHINA S. GHAZEERI, ANWAR H. NASSAR, ZEINA YOUNES & JOHNNY T. AWWAD. (2012) Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview. Acta Obstetricia et Gynecologica Scandinavica 91:6, pages 658-678.
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Nicolette OostdamMireille N.M. van PoppelMaurice G.A.J. WoutersWillem van Mechelen. (2011) Interventions for Preventing Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis. Journal of Women's Health 20:10, pages 1551-1563.
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Richard S. Legro. (2010) Metformin during Pregnancy in Polycystic Ovary Syndrome: Another Vitamin Bites the Dust. The Journal of Clinical Endocrinology & Metabolism 95:12, pages 5199-5202.
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O. Verier-Mine. (2010) Outcomes in women with a history of gestational diabetes. Screening and prevention of type 2 diabetes. Literature review. Diabetes & Metabolism 36:6, pages 595-616.
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O. Vérier-Mine. (2010) Devenir maternel après un diabète gestationnel. Dépistage et prévention du diabète de type 2. Revue de la littérature. Journal de Gynécologie Obstétrique et Biologie de la Reproduction 39:8, pages S299-S321.
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S. M. Nelson, P. Matthews & L. Poston. (2009) Maternal metabolism and obesity: modifiable determinants of pregnancy outcome. Human Reproduction Update 16:3, pages 255-275.
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