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INVITED REVIEWS

CSF spectrophotometry for bilirubin – why and how?

Pages 1-7 | Received 06 Aug 2008, Accepted 12 Nov 2008, Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Musa China, Samir A. Matloob, Joan P. Grieve & Ahmed K. Toma. (2021) The value of repeated lumbar puncture to test for xanthochromia, in patients with clinical suspicion of subarachnoid haemorrhage, with CT-negative and initial traumatic tap. British Journal of Neurosurgery 35:4, pages 476-479.
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Carlos Emilio Rodríguez. (2020) New method for the determination of the net bilirubin absorbance in cerebrospinal fluid that minimizes the interference of oxyhaemoglobin and biliverdin. Scandinavian Journal of Clinical and Laboratory Investigation 80:1, pages 81-86.
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Articles from other publishers (15)

Rozerin Kevci, Anders Lewén, Elisabeth Ronne-Engström, Fartein Velle, Per Enblad & Teodor Svedung Wettervik. (2023) Lumbar puncture-verified subarachnoid hemorrhage: bleeding sources, need of radiological examination, and functional recovery. Acta Neurochirurgica.
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Marcus Clarin, Annika Petersson, Henrik Zetterberg & Kim Ekblom. (2022) Detection of subarachnoid haemorrhage with spectrophotometry of cerebrospinal fluid – a comparison of two methods. Clinical Chemistry and Laboratory Medicine (CCLM) 60:7, pages 1053-1057.
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Wan Yung Siu, William Thomas, Rikin Trivedi, Alexandra Hogan, Umbareen Siddiqi, Anita Sarker & Martin Wolfgang Besser. (2020) Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?. Clinical Case Reports 8:5, pages 894-899.
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Sophie Bittermann, Christof Schild, Eliane Marti, Jelena Mirkovitch, Daniela Schweizer & Diana Henke. (2019) Analysis of blood degradation products and ferritin in the cerebrospinal fluid of dogs with acute thoracolumbar intervertebral disk extrusion, a prospective pilot study. BMC Veterinary Research 15:1.
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Perrin T. Considine, Levi Filler & Murtaza Akhter. 2018. Neurologic Emergencies. Neurologic Emergencies 143 173 .
Anne Gangloff, Linda Nadeau, Jeffrey J. Perry, Pierre Baril & Marcel Émond. (2015) Ruptured aneurysmal subarachnoid hemorrhage in the emergency department: Clinical outcome of patients having a lumbar puncture for red blood cell count, visual and spectrophotometric xanthochromia after a negative computed tomography. Clinical Biochemistry 48:10-11, pages 634-639.
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Kevin H Chu, Roderick O Bishop & Anthony FT Brown. (2015) Spectrophotometry, not visual inspection for the detection of xanthochromia in suspected subarachnoid haemorrhage: A debate. Emergency Medicine Australasia 27:3, pages 267-272.
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Angus Hann, Kevin Chu, Jaimi Greenslade, Julian Williams & Anthony Brown. (2015) Benefit of cerebrospinal fluid spectrophotometry in the assessment of CT scan negative suspected subarachnoid haemorrhage: A diagnostic accuracy study. Journal of Clinical Neuroscience 22:1, pages 173-179.
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Kevin Chu, Angus Hann, Jaimi Greenslade, Julian Williams & Anthony Brown. (2014) Spectrophotometry or Visual Inspection to Most Reliably Detect Xanthochromia in Subarachnoid Hemorrhage: Systematic Review. Annals of Emergency Medicine 64:3, pages 256-264.e5.
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Andrew Smith, Alan H.B. Wu, Kara L. Lynch, Nerissa Ko & David G. Grenache. (2013) Multi-wavelength spectrophotometric analysis for detection of xanthochromia in cerebrospinal fluid and accuracy for the diagnosis of subarachnoid hemorrhage. Clinica Chimica Acta 424, pages 231-236.
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I. M. E. Alons, R. J. Verheul, G. A. E. Ponjee & K. Jellema. (2012) Optimizing blood pigment analysis in cerebrospinal fluid for the diagnosis of subarachnoid haemorrhage – a practical approach. European Journal of Neurology 20:1, pages 193-197.
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Ben L. C. Wright, James T. F. Lai & Alexandra J. Sinclair. (2012) Cerebrospinal fluid and lumbar puncture: a practical review. Journal of Neurology 259:8, pages 1530-1545.
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P. J. Lindsberg. (2011) Ruling out subarachnoid hemorrhage. European Journal of Neurology 18:2, pages 205-206.
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Clementine YF Yap & Tar Choon Aw. (2010) Revisting Cerebrospinal Fluid (CSF) Examination. Proceedings of Singapore Healthcare 19:4, pages 355-359.
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O Muhammed, D Teubner, DN Jones & JP Slavotinek. (2010) ORIGINAL ARTICLE: Retrospective audit of the investigation of patients with suspected acute subarachnoid haemorrhage. Journal of Medical Imaging and Radiation Oncology 54:4, pages 339-346.
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