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Original Article

A Method for Semiquantitative Determination of 1-Methyl-4-Imidazoleacetic Acid in Human Urine

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Pages 483-490 | Received 11 Feb 1965, Published online: 28 Aug 2009

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Read on this site (14)

Steve L. Taylor & Ronald R. Eitenmiller. (1986) Histamine Food Poisoning: Toxicology and Clinical Aspects. CRC Critical Reviews in Toxicology 17:2, pages 91-128.
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Goran Granerus, Jan Bergmark & John G. Kral. (1979) Histamine metabolism in severe obesity before and after jejuno-ileostomy. Scandinavian Journal of Clinical and Laboratory Investigation 39:7, pages 671-675.
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G. Granerus, B. Gillbrand & H. Wetterqvist. (1977) Histamine Metabolism in Normal Pregnancy and in Toxaemia of Pregnancy. Acta Obstetricia et Gynecologica Scandinavica 56:2, pages 81-86.
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F. Jonassen, H. Wetterqvist & G. Granerus. (1976) Histamine Metabolism and Female Sex Hormones in Women. Acta Obstetricia et Gynecologica Scandinavica 55:5, pages 387-394.
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F. Jonassen, G. Granerus & H. Wetterqvist. (1976) Histamine Metabolism During the Menstrual Cycle. Acta Obstetricia et Gynecologica Scandinavica 55:4, pages 297-304.
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P. Agrup, G. Granerus, S. Jacobsson, H. Wetterqvist & T. White. (1974) Histamine Metabolism in Burn Injuries. Scandinavian Journal of Plastic and Reconstructive Surgery 8:3, pages 198-201.
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J. Bergmark & G. Granerus. (1974) Ion Exchange Chromatography for Quantitative Analysis of Radioactive Histamine Metabolites in Human Urine. Scandinavian Journal of Clinical and Laboratory Investigation 34:4, pages 365-373.
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H. Westling. (1969) Editorial: Evaluation of Histamine Metabolism in Man. Scandinavian Journal of Clinical and Laboratory Investigation 23:1, pages 1-4.
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G. Granerus. (1968) Urinary Excretion of Histamine, Methylhistamine and Methylimidazoleacetic Acids in Man under Standardized Dietary Conditions. Scandinavian Journal of Clinical and Laboratory Investigation 21:sup104, pages 59-68.
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G. Granerus. (1968) Effects of Oral Histamine, Histidine and Diet on Urinary Excretion of Histamine, Methylhistamine and 1-Methyl-4-imidazoleacetic Acid in Man. Scandinavian Journal of Clinical and Laboratory Investigation 21:sup104, pages 49-58.
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G. Granerus, H. Wetterqvist & T. White. (1968) Histamine Metabolism in Healthy Subjects before and during Treatment with Aminoguanidine. Scandinavian Journal of Clinical and Laboratory Investigation 21:sup104, pages 39-48.
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H. Wetterqvist & T. White. (1968) Urinary Excretion of Histamine and Methylhistamine in Male and Female Rats. Scandinavian Journal of Clinical and Laboratory Investigation 21:sup104, pages 3-12.
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Arend Bouhuys, A. Barbero, S.-E. Lindell, S. A. Roach & R. S. F. Schilling. (1967) Byssinosis in Hemp Workers. Archives of Environmental Health: An International Journal 14:4, pages 533-543.
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R. Tham. (1966) Liberation of Histamine in Man Gas Chromatography of Ring Methylated Imidazoleacetic Acids in Urine. Scandinavian Journal of Clinical and Laboratory Investigation 18:6, pages 603-616.
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Articles from other publishers (35)

A S Kelvin. (1968) Determination of methylimidazoleacetic acids in human urine by gas chromatography. Journal of Pharmacy and Pharmacology 20:8, pages 659-661.
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W. A. Fogel, K. A. Michelsen, G. Granerus, K. Sasiak, W. Andrzejewski, P. Panula & C. Maslinski. (2002) Neuronal storage of histamine in the brain and tele ‐methylimidazoleacetic acid excretion in portocaval shunted rats . Journal of Neurochemistry 80:3, pages 375-382.
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S. Vind, I. Søndergaard, L. Kergaard Poulsen, U. Gerner Svendsen & B. Weeke. (2007) Comparison of methods for intestinal histamine application: histamine in enterosoluble capsules or via a duodeno‐jenunal tube. Allergy 46:3, pages 191-195.
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Göran Granerus & Urban Wass. (1984) Urinary excretion of histamine, methylhistamine (1-MeHi) and methylimidazoleacetic acid (MeImAA) in mastocytosis: Comparison of new HPLC methods with other present methods. Agents and Actions 14:3-4, pages 341-345.
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D.E. Duggan, K.F. Hooke & H.G. Ramjit. (1984) Sensitive gas—liquid chromatographic procedure for urinary Nτ-methylimidazole acetic acid, an index of histamine turnover. Journal of Chromatography B: Biomedical Sciences and Applications 306, pages 69-77.
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Julia Y. Hui & Steve L. Taylor. (1984) Reversed-phase ion-pair high-performance liquid chromatographic procedure for determination of histamine and its metabolites in rat urine. Journal of Chromatography A 312, pages 443-449.
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Göran Granerus, Jon H. Olafsson & Gösta Roupe. (1983) Studies on Histamine Metabolism in Mastocytosis. Journal of Investigative Dermatology 80:5, pages 410-416.
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Göran Granerus, Aleksander Weinfeld & Jan Westin. (1983) Histamine symptoms and histamine metabolism in chronic granulocytic leukaemia. Agents and Actions 13:2-3, pages 251-255.
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Ib Søndergaard. (2007) Quantitative Determination of 1,4‐Methyl‐Imidazoleacetic Acid in Urine by High Performance Liquid Chromatography. Allergy 37:8, pages 581-586.
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J.J. Keyzer, B.G. Wolthers, H. Breukelman, H.F. Kauffman & J.G.R. de Monchy. (1982) Determination of Nτ-methylimidazoleacetic acid (a histamine metabolite) in urine by gas chromatography using nitrogen-phosphorus detection. Clinica Chimica Acta 121:3, pages 379-387.
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Michael A. Beaven, Nancy B. Roderick, Richard E. Shaff & Andrew H. Soll. (1982) Histamine synthesis in intact and disrupted rat mast cells. Biochemical Pharmacology 31:7, pages 1189-1195.
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Göran Granerus & Gösta Roupe. (1982) Increased urinary methylimidazoleacetic acid (MelmAA) as an indicator of systemic mastocytosis. Agents and Actions 12:1-2, pages 29-31.
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Göran Granerus, Gösta Roupe & Gunnar Swanbeck. (1981) Decreased Urinary Histamine Metabolite after Successful PUVA Treatment of Urticaria Pigmentosa. Journal of Investigative Dermatology 76:1, pages 1-3.
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O. Löwhagen, G. Granerus & H. Wetterqvist. (2007) Studies on Histamine Metabolism in Allergen‐Induced Asthma. Allergy 35:6, pages 521-529.
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O. Löwhagen, G. Granerus & H. Wetterqvist. (2007) Studies on Histamine Metabolism in Intrinsic Bronchial Asthma. Allergy 34:6, pages 395-404.
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R. W. Schayer, H. Wetterqvist, Mauricio A. Beaven & Z. Horakova. 1978. Histamine II and Anti-Histaminics. Histamine II and Anti-Histaminics 109 173 .
Ottar Sjaastad & Ø. V. Sjaastad. (2009) METABOLISM OF HISTAMINE IN MYOTONIC DYSTROPHY A DUAL PATTERN OF INACTIVATION OF INTESTINAL HISTAMINE. Acta Neurologica Scandinavica 56:5, pages 413-429.
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Ottar Sjaastad & �. V. Sjaastad. (1977) Urinary histamine excretion in migraine and cluster headache. Journal of Neurology 216:2, pages 91-104.
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S.K. Wadman & P.K.dee Bree. 1976. Paper and Thin Layer Chromatography. Paper and Thin Layer Chromatography 122 138 .
Robert M. Schwartzman & R.E.W. Halliwell. (1975) Thin-layer chromatographic assays of histamine and its metabolites in urine of man and dog. Journal of Chromatography A 115:1, pages 129-138.
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Jan Westin, Göran Granerus, Aleksander Weinfeld & Hakon Wetterquist. (2009) Histamine Metabolism in Polycythaemia Vera. Scandinavian Journal of Haematology 15:1, pages 45-57.
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Robert M. Schwartzman. (1973) Quantitative thin-layer chromatography of histamine and its metabolites. Journal of Chromatography A 86, pages 263-268.
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Elizabeth Evans & P.J. Nicholls. (1973) A method for the gas chromatographic determination of urinary 1,4-methyl-imidazoleacetic acid. Journal of Chromatography A 82:2, pages 394-397.
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Knut Arnet Eliassen. (2008) Effect of Histamine Loading on the Metabolism of 14 C‐Histarnine, Administered Intravenously or Orally, in Domestic Animals (Goat and Pig) . Acta Physiologica Scandinavica 88:3, pages 303-316.
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Knut Arnet Eliassen. (2008) Metabolism of 14 C‐Histamine in Goats and Pigs Treated with Aminoguanidine . Acta Physiologica Scandinavica 88:1, pages 1-7.
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B. BERG, G. GRANERUS, MAJ‐BRITT JOHANSSON, H. WESTLING & T. WHITE. (2012) Histamine formation from 14 C‐ l ‐histidine in man . British Journal of Pharmacology 46:2, pages 270-280.
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K. A. Eliassen. (2008) Metabolism of 14 C‐Histamine in Domestic Animals . Acta Physiologica Scandinavica 81:3, pages 289-299.
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Bertel Berg, Göran Granerus, Håkan Westling & Thomas White. (2009) Urinary Excretion of Histamine and Histamine Metabolites in Leukaemia. Scandinavian Journal of Haematology 8:1, pages 63-68.
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G. GRANERUS, S.‐E. SVENSSON, H. WETTERQVIST & T. WHITE. (2007) THE METABOLISM OF HISTAMINE IN A CASE OF COLD URTICARIA. Allergy 24:4-5, pages 258-260.
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Ottar Sjaastad. (2009) INCREASED ENTERIC FORMATION OF HISTAMINE IN CHRONIC PANCREATITIS. Acta Medica Scandinavica 186:1-6, pages 125-133.
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B. Berg, H. Wetterqvist & T. White. (2009) MASTOCYTOSIS TREATED WITH L‐HYOSCYAMINE (EGAZIL®). Acta Medica Scandinavica 184:1-6, pages 383-387.
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G. Granerus, L. Hallberg, A.‐B. Laurell & H. Wetterquist. (2009) Studies on the Histamine Metabolism and the Complement System in Hereditary Angioneurotic Edema. Acta Medica Scandinavica 182:1, pages 11-22.
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G. Granérus, S.E. Lindell, J. Waldenström, H. Westling & T. White. (1966) HISTAMINE METABOLISM IN CARCINOIDOSIS. The Lancet 287:7449, pages 1267-1268.
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H.N. WagnerJR.JR.. (1966) PULMONARY BLOOD-FLOW IN LUNG CANCER. The Lancet 287:7449, pages 1267.
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Georg Kahlson, Elsa Rosengren & R. Thunberg. (1966) ACCELERATED HISTAMINE FORMATION IN HYPERSENSITIVITY REACTIONS. The Lancet 287:7441, pages 782-784.
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